| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9353 |
Name | SLIT2 |
Synonym | SLIL3|Slit-2;slit homolog 2 (Drosophila);SLIT2;slit homolog 2 (Drosophila) |
Definition | slit homolog 2 protein |
Position | 4p15.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Axon guidance mediated by Slit/Robo;PANTHER;P00008 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Glypican 1 network;PID Curated;200021 |
Pathway | Regulation of Commissural axon pathfinding by Slit and Robo;PID Reactome;500093 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Signaling by Robo receptor;PID Reactome;500092 |
Disease | Pulmonary fibrosis;FunDO |
Disease | Echocardiographic traits;NHGRI |
Disease | Cancer;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | Echocardiographic traits;GAD |
External Links | |
Links to Entrez Gene | 9353 |
Links to all GeneRIF Items | 9353 |
Links to iHOP | 9353 |
Sequence Information | |
Nucleotide Sequence | >9353 : length: 8045 GAAGCGCCCGGACGGCGGAGCTTGGCGGCGGCGGTGGTGGTGGCTGCCGCAGACTGTGGT TAAAAAAAAGAAGGCGGCGGCGGCGGCGGCGGCGGAGGCGGAGGCAGCTGCGAGGCATGG GAGCGCCGAAGCGCCCAGGCGCAGGCCGAAGCTGCCGCGCTTTCTGGGCACGGCGGGAGT GCTGAGCAGAAAGGGGAGCGCCGGGGGCCCGCAGCCGGCTCCGGAGGCGCGGGCCGGGTT TTTGTTTGGCTACGCTGAGCGCCAGTCAGCCCCAGCGAACAACTCCAGTTACGACAACAA CCCACCTTCCTTCCAGACAAGCGAGACTTGGGCTGCTGCGTCCGTCCTATTGTTTAGACA CTTGCCAGGGGCTCCGGAGTCGGCAGAGCCACCGAGTCCCCGCTCTGAGTCGTCGCCCTC CCTCTCCCCGACCTCGCTCCCTGGAGCGGGAGGCCAGGAAAGCAGCGGGAGAGGGGAAGG GGCTAGAAGGAGAAGGACTACCCGGGACTGCGGCCGCCGCGTCAGGTGCAGCGCCAGGAG CCGGGCGGCGTCGCCACGCCGGCAGGGGTACCGCCACTGTGGCCTTGGGGGACGGAATTC AAAGCCTGGGAAAAGTTGCTGCACTTTGAGAAGGACGAACCACTAGTGGGAGACCGCCGG GGGCCGGCCGTGGCTCTGCGCCCTCCGGAACCCGGCTCTTGTTTCTTCTACCTTTGCCAT CAGGTGTCTGCCGCGGAGCTGCGGCTTATCTGGGAGACGAGCGGGGTTGACACGCGCGCA CACACTACTGCCATTCAGCTGCCGCCTGGCTCTGCCTGGAGTAGTGGATCCCACCCGCCC ACCTGCCACCGAGCCATTCTCCAGTACGCCCCAGCAGGACGCTGACACCTCCAACCTTGG CCTTTGCCTTTCCACTCCTTCCGGTCTGCCTGGTTTTTAAGTCCGCCCCCAGTCAGTCCC CACTCAGTCTTCGCAGCAGCTCTCATCCTCCACTTGGCCTCTTGGAGTTCCTCGCCGGAG TGCTGACTAGTGGATATTTCTGCCCGGCTGCGGCGGCCCGACTGCCCTTTTGTCTTTTCT GCGTGACCTCGGGGCAGGTCCTGGTGCAGAGCGTCGCCAAGGACGCCGAGCGGGAGGCGG GATTGCCCAGACATCCTTCAGCGAAGTGCATGTGTGTTTGTAAACCATCGTTGGCTGTCG GGAGACCGCGAGGACCGGTCCAGGCTGCGGCGGAGTCGAGGGCGAGGGAGAGGCCGCGTG AGTGAGCAGAGTCCAGAGCCGTGCGCCCCCAGAACTGCGCGTCCGCCCCGTGCACCCCCG CGCGCCATGCCCAGTTGCCCCGCGCGCTCTGCTACGGGCCCGCTGGGCTTCCGCGCCTTC TAGCTTCCGGAGCCCACTTTGATCGGGGCCATAATACCTATTGAGATCCCCTCTTCTGTC TTGTACCTTCGCCACTGGCATCGGATTTGCAGAAGCGTGCGTGGGATCAGAGGACCGCCC TCCCCACAACAACCGGCCCCTGCATCTTAGCAGCCGTTGGAAGCCCCAGCTCTTTTACCG CCAAGTTCATCCTTGGGAGACAGAAGACGCGTGATCTCCTCTCCGCTGCTCTTGGGGTCT CCTTGCAGCCCTGGCCAGGCGGATTCATCCTCAGGACCTAAAGTTGCCCAAGGAGCTCCT GCTCTGCCAGAGGAGGGTGGAGAGGGCGGTGGGAGGCGTGTGCCTGAGTGGGCTCTACTG CCTTGTTCCATATTATTTGGTGCACATTTTCCCTGGCACTCTGGGTTGCTAGCCCCGCCG GGCACTGGGCCTCAGACACTGCGCGGTTCCCTCGGAGCAGCAAGCTAAAGAAAGCCCCCA GTGCCGGCGAGGAAGGAGGCGGCGGGGAAAGATGCGCGGCGTTGGCTGGCAGATGCTGTC CCTGTCGCTGGGGTTAGTGCTGGCGATCCTGAACAAGGTGGCACCGCAGGCGTGCCCGGC GCAGTGCTCTTGCTCGGGCAGCACAGTGGACTGTCACGGGCTGGCGCTGCGCAGCGTGCC CAGGAATATCCCCCGCAACACCGAGAGACTGGATTTAAATGGAAATAACATCACAAGAAT TACGAAGACAGATTTTGCTGGTCTTAGACATCTAAGAGTTCTTCAGCTTATGGAGAATAA GATTAGCACCATTGAAAGAGGAGCATTCCAGGATCTTAAAGAACTAGAGAGACTGCGTTT AAACAGAAATCACCTTCAGCTGTTTCCTGAGTTGCTGTTTCTTGGGACTGCGAAGCTATA CAGGCTTGATCTCAGTGAAAACCAAATTCAGGCAATCCCAAGGAAAGCTTTCCGTGGGGC AGTTGACATAAAAAATTTGCAACTGGATTACAACCAGATCAGCTGTATTGAAGATGGGGC ATTCAGGGCTCTCCGGGACCTGGAAGTGCTCACTCTCAACAATAACAACATTACTAGACT TTCTGTGGCAAGTTTCAACCATATGCCTAAACTTAGGACTTTTCGACTGCATTCAAACAA CCTGTATTGTGACTGCCACCTGGCCTGGCTCTCCGACTGGCTTCGCCAAAGGCCTCGGGT TGGTCTGTACACTCAGTGTATGGGCCCCTCCCACCTGAGAGGCCATAATGTAGCCGAGGT TCAAAAACGAGAATTTGTCTGCAGTGATGAGGAAGAAGGTCACCAGTCATTTATGGCTCC TTCTTGTAGTGTTTTGCACTGCCCTGCCGCCTGTACCTGTAGCAACAATATCGTAGACTG TCGTGGGAAAGGTCTCACTGAGATCCCCACAAATCTTCCAGAGACCATCACAGAAATACG TTTGGAACAGAACACAATCAAAGTCATCCCTCCTGGAGCTTTCTCACCATATAAAAAGCT TAGACGAATTGACCTGAGCAATAATCAGATCTCTGAACTTGCACCAGATGCTTTCCAAGG ACTACGCTCTCTGAATTCACTTGTCCTCTATGGAAATAAAATCACAGAACTCCCCAAAAG TTTATTTGAAGGACTGTTTTCCTTACAGCTCCTATTATTGAATGCCAACAAGATAAACTG CCTTCGGGTAGATGCTTTTCAGGATCTCCACAACTTGAACCTTCTCTCCCTATATGACAA CAAGCTTCAGACCATCGCCAAGGGGACCTTTTCACCTCTTCGGGCCATTCAAACTATGCA TTTGGCCCAGAACCCCTTTATTTGTGACTGCCATCTCAAGTGGCTAGCGGATTATCTCCA TACCAACCCGATTGAGACCAGTGGTGCCCGTTGCACCAGCCCCCGCCGCCTGGCAAACAA AAGAATTGGACAGATCAAAAGCAAGAAATTCCGTTGTTCAGCTAAAGAACAGTATTTCAT TCCAGGTACAGAAGATTATCGATCAAAATTAAGTGGAGACTGCTTTGCGGATCTGGCTTG CCCTGAAAAGTGTCGCTGTGAAGGAACCACAGTAGATTGCTCTAATCAAAAGCTCAACAA AATCCCGGAGCACATTCCCCAGTACACTGCAGAGTTGCGTCTCAATAATAATGAATTTAC CGTGTTGGAAGCCACAGGAATCTTTAAGAAACTTCCTCAATTACGTAAAATAAACTTTAG CAACAATAAGATCACAGATATTGAGGAGGGAGCATTTGAAGGAGCATCTGGTGTAAATGA AATACTTCTTACGAGTAATCGTTTGGAAAATGTGCAGCATAAGATGTTCAAGGGATTGGA AAGCCTCAAAACTTTGATGTTGAGAAGCAATCGAATAACCTGTGTGGGGAATGACAGTTT CATAGGACTCAGTTCTGTGCGTTTGCTTTCTTTGTATGATAATCAAATTACTACAGTTGC ACCAGGGGCATTTGATACTCTCCATTCTTTATCTACTCTAAACCTCTTGGCCAATCCTTT TAACTGTAACTGCTACCTGGCTTGGTTGGGAGAGTGGCTGAGAAAGAAGAGAATTGTCAC GGGAAATCCTAGATGTCAAAAACCATACTTCCTGAAAGAAATACCCATCCAGGATGTGGC CATTCAGGACTTCACTTGTGATGACGGAAATGATGACAATAGTTGCTCCCCACTTTCTCG CTGTCCTACTGAATGTACTTGCTTGGATACAGTCGTCCGATGTAGCAACAAGGGTTTGAA GGTCTTGCCGAAAGGTATTCCAAGAGATGTCACAGAGTTGTATCTGGATGGAAACCAATT TACACTGGTTCCCAAGGAACTCTCCAACTACAAACATTTAACACTTATAGACTTAAGTAA CAACAGAATAAGCACGCTTTCTAATCAGAGCTTCAGCAACATGACCCAGCTCCTCACCTT AATTCTTAGTTACAACCGTCTGAGATGTATTCCTCCTCGCACCTTTGATGGATTAAAGTC TCTTCGATTACTTTCTCTACATGGAAATGACATTTCTGTTGTGCCTGAAGGTGCTTTCAA TGATCTTTCTGCATTATCACATCTAGCAATTGGAGCCAACCCTCTTTACTGTGATTGTAA CATGCAGTGGTTATCCGACTGGGTGAAGTCGGAATATAAGGAGCCTGGAATTGCTCGTTG TGCTGGTCCTGGAGAAATGGCAGATAAACTTTTACTCACAACTCCCTCCAAAAAATTTAC CTGTCAAGGTCCTGTGGATGTCAATATTCTAGCTAAGTGTAACCCCTGCCTATCAAATCC GTGTAAAAATGATGGCACATGTAATAGTGATCCAGTTGACTTTTACCGATGCACCTGTCC ATATGGTTTCAAGGGGCAGGACTGTGATGTCCCAATTCATGCCTGCATCAGTAACCCATG TAAACATGGAGGAACTTGCCACTTAAAGGAAGGAGAAGAAGATGGATTCTGGTGTATTTG TGCTGATGGATTTGAAGGAGAAAATTGTGAAGTCAACGTTGATGATTGTGAAGATAATGA CTGTGAAAATAATTCTACATGTGTCGATGGCATTAATAACTACACATGCCTTTGCCCACC TGAGTATACAGGTGAGTTGTGTGAGGAGAAGCTGGACTTCTGTGCCCAGGACCTGAACCC CTGCCAGCACGATTCAAAGTGCATCCTAACTCCAAAGGGATTCAAATGTGACTGCACACC AGGGTACGTAGGTGAACACTGCGACATCGATTTTGACGACTGCCAAGACAACAAGTGTAA AAACGGAGCCCACTGCACAGATGCAGTGAACGGCTATACGTGCATATGCCCCGAAGGTTA CAGTGGCTTGTTCTGTGAGTTTTCTCCACCCATGGTCCTCCCTCGTACCAGCCCCTGTGA TAATTTTGATTGTCAGAATGGAGCTCAGTGTATCGTCAGAATAAATGAGCCAATATGTCA GTGTTTGCCTGGCTATCAGGGAGAAAAGTGTGAAAAATTGGTTAGTGTGAATTTTATAAA CAAAGAGTCTTATCTTCAGATTCCTTCAGCCAAGGTTCGGCCTCAGACGAACATAACACT TCAGATTGCCACAGATGAAGACAGCGGAATCCTCCTGTATAAGGGTGACAAAGACCATAT CGCGGTAGAACTCTATCGGGGGCGTGTTCGTGCCAGCTATGACACCGGCTCTCATCCAGC TTCTGCCATTTACAGTGTGGAGACAATCAATGATGGAAACTTCCACATTGTGGAACTACT TGCCTTGGATCAGAGTCTCTCTTTGTCCGTGGATGGTGGGAACCCCAAAATCATCACTAA CTTGTCAAAGCAGTCCACTCTGAATTTTGACTCTCCACTCTATGTAGGAGGCATGCCAGG GAAGAGTAACGTGGCATCTCTGCGCCAGGCCCCTGGGCAGAACGGAACCAGCTTCCACGG CTGCATCCGGAACCTTTACATCAACAGTGAGCTGCAGGACTTCCAGAAGGTGCCGATGCA AACAGGCATTTTGCCTGGCTGTGAGCCATGCCACAAGAAGGTGTGTGCCCATGGCACATG CCAGCCCAGCAGCCAGGCAGGCTTCACCTGCGAGTGCCAGGAAGGATGGATGGGGCCCCT CTGTGACCAACGGACCAATGACCCTTGCCTTGGAAATAAATGCGTACATGGCACCTGCTT GCCCATCAATGCGTTCTCCTACAGCTGTAAGTGCTTGGAGGGCCATGGAGGTGTCCTCTG TGATGAAGAGGAGGATCTGTTTAACCCATGCCAGGCGATCAAGTGCAAGCATGGGAAGTG CAGGCTTTCAGGTCTGGGGCAGCCCTACTGTGAATGCAGCAGTGGATACACGGGGGACAG CTGTGATCGAGAAATCTCTTGTCGAGGGGAAAGGATAAGAGATTATTACCAAAAGCAGCA GGGCTATGCTGCTTGCCAAACAACCAAGAAGGTGTCCCGATTAGAGTGCAGAGGTGGGTG TGCAGGAGGGCAGTGCTGTGGACCGCTGAGGAGCAAGCGGCGGAAATACTCTTTCGAATG CACTGACGGCTCCTCCTTTGTGGACGAGGTTGAGAAAGTGGTGAAGTGCGGCTGTACGAG GTGTGTGTCCTAAACACACTCCCGGCAGCTCTGTCTTTGGAAAAGGTTGTATACTTCTTG ACCGTGTGGGACTAATGAATGCTTCATAGTGGAAATATTTGAAATATATTGTAAAATACA GAACAGACTTATTTTTATTATGAGAATAAAGACTTTTTTTCTGCATTTGGAAAAAAAAAA AAAGAAATGCTTGAACTAAAGCTTCCCCTATGCTGGAGAAGTATGAAGAAAGATATACCT GGAGACATTAGAACAGCGATGGGAACCATTGCAACTCGGGTCCATCTTTGTAACATGCTG AAGACAAGCAGAAGCACATGCACGAGGGACAGAGGAGCTACTGTGCACTGCTGTGAAATT GCCCAGAGCATAAAACCTGTGTACCCTCCTTCACATCAACCAAGTTCACTAGGACATACC AAGCACATGCGTGTGAATGAGGATGCAAGGCAAGAGAATGGAACTCCAGAATTCACAGAT AGAACAAATGGATGAGAAATATTTCATGCAAAATATAAAGTGTCCTGAGGATCTGGGTTC CATTTACGAGAGGAAATGAAAGTGCTAAAATAAATTTTATCTTCCTTTTAAATGTCAGCA TGTCAGCAGAAGCAGCACACAAAAGTCTTTACCATTTTCCAGTATTAATTTTTTTGTAAT ATAAATGATAAAGGAGATGATAAAGAACCAATAGATTATTGATAAATAAATTAGTAATAA TATGATTTTTTGTTTCTATGAGTTCTAAACAGCCCTATACAGTATTCAGTTTCCATGAGA AATATTTATTGTATCAAAGTACATTGTACTTAACATTTTAGGCCATCCTTTTACTGTTCC TTGATGCTTTAATATATATTAATTTATAATTATCCTGATATTTTTGTACATTTTTCAAAC TTAAAAATCAGGATTTTTTTTTTTTTTTTTTTGGCAATAGTACTAACATAGGGTTTTATC TTGGGATACATATGTATTGGTCTGTTTGTTGACCTTGACATCTGATCACTGATGTCAATG ACCTACTGGCCTCATTCAGGACACCTGCAGAGAGTATGCAAAGTCCGAGAGAGGAAAACA GAAATCTGTATGTGAGATGGTCATTGTACAGAAAGAAGTGGCCCCTCTGCAACATGTCCT CACAGAAACGAAATGGTGTGTAGCAATCAACACTAGAAAGTAGACCTTTTGCAAATTAAT ATGTCCTTGACCTTTTTTGCCCTTTTGTGGGGGTGAGGTGGGGATAAAAAGACTGTCATA TCAAGAACTGTGACTTTTCTTTCCCTCAAACAATAAAACTCCTTTATTATCTTAATGCTC CCATGTTAACATGTTTGCTGCTAAATTACAATGTAGAATTGATAATGGTTTATAGTGAAC TGTGCTCTTCCCTCATTAAAATCCCAGGGTGCCCTGTAAAGATGCAGATGTTTCTTCCTG AAAACTTCTTTTTTTACAAAGAAAATTAGATGTACATGTATAATTCAGTGTGCTTTGTCT TTCTCCAGATTAATATCGGTTACACTGCTGATGTTTGTAAATTAAACAGATATTTACTTC ATTAA |
Protein Sequence | >9353 : length: 1533 MRGVGWQMLSLSLGLVLAILNKVAPQACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERL DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPE LLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVL TLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPS HLRGHNVAEVQKREFVCSDEEEGHQSFMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPT NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLY GNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTF SPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKF RCSAKEQYFIPGTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTA ELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLEN VQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSL STLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGN DDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNY KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGND ISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADKL LLTTPSKKFTCQGPVDVNILAKCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDV PIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDG INNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDID FDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQC IVRINEPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKVRPQTNITLQIATDEDSGI LLYKGDKDHIAVELYRGRVRASYDTGSHPASAIYSVETINDGNFHIVELLALDQSLSLSV DGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSE LQDFQKVPMQTGILPGCEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCL GNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYC ECSSGYTGDSCDREISCRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGGQCCGPLR SKRRKYSFECTDGSSFVDEVEKVVKCGCTRCVS |