| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8742 |
Name | TNFSF12 |
Synonym | APO3L|DR3LG|TWEAK;tumor necrosis factor (ligand) superfamily, member 12;TNFSF12;tumor necrosis factor (ligand) superfamily, member 12 |
Definition | APO3 ligand|APO3/DR3 ligand|TNF-related WEAK inducer of apoptosis|tumor necrosis factor ligand superfamily member 12 |
Position | 17p13 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | induction of apoptosis through dr3 and dr4/5 death receptors;PID BioCarta;100189 |
External Links | |
Links to Entrez Gene | 8742 |
Links to all GeneRIF Items | 8742 |
Links to iHOP | 8742 |
Sequence Information | |
Nucleotide Sequence | >8742 : length: 1642 CTCTCCCCGGCCCGATCCGCCCGCCGGCTCCCCCTCCCCCGATCCCTCGGGTCCCGGGAT GGGGGGGCGGTGAGGCAGGCACAGCCCCCCGCCCCCATGGCCGCCCGTCGGAGCCAGAGG CGGAGGGGGCGCCGGGGGGAGCCGGGCACCGCCCTGCTGGTCCCGCTCGCGCTGGGCCTG GGCCTGGCGCTGGCCTGCCTCGGCCTCCTGCTGGCCGTGGTCAGTTTGGGGAGCCGGGCA TCGCTGTCCGCCCAGGAGCCTGCCCAGGAGGAGCTGGTGGCAGAGGAGGACCAGGACCCG TCGGAACTGAATCCCCAGACAGAAGAAAGCCAGGATCCTGCGCCTTTCCTGAACCGACTA GTTCGGCCTCGCAGAAGTGCACCTAAAGGCCGGAAAACACGGGCTCGAAGAGCGATCGCA GCCCATTATGAAGTTCATCCACGACCTGGACAGGACGGAGCGCAGGCAGATGGAGGTTAC ACAACTTGTCTGAGGCCATGAGATACTAAGTGGTGGAGCCAAGATTTGAACCCAGCTAGA ATGTGCCTGTGTACTGGACATGGTCTGCATGAAAGGCGAGGTGGCTGGTGCAGGGGTGAG GGGTCCATGCAGGGGCCACATCCAAAAAGGGGAGAGGGAAGTTTCCAGAAAGAAGAGAGG ACACATCTCCCACCATTACCAGAGGGTCAAAGGAGAACAAGAGACCAGGTGTGGACGGGA CAGTGAGTGGCTGGGAGGAAGCCAGAATCAACAGCTCCAGCCCTCTGCGCTACAACCGCC AGATCGGGGAGTTTATAGTCACCCGGGCTGGGCTCTACTACCTGTACTGTCAGGTGCACT TTGATGAGGGGAAGGCTGTCTACCTGAAGCTGGACTTGCTGGTGGATGGTGTGCTGGCCC TGCGCTGCCTGGAGGAATTCTCAGCCACTGCGGCGAGTTCCCTCGGGCCCCAGCTCCGCC TCTGCCAGGTGTCTGGGCTGTTGGCCCTGCGGCCAGGGTCCTCCCTGCGGATCCGCACCC TCCCCTGGGCCCATCTCAAGGCTGCCCCCTTCCTCACCTACTTCGGACTCTTCCAGGTTC ACTGAGGGGCCCTGGTCTCCCCGCAGTCGTCCCAGGCTGCCGGCTCCCCTCGACAGCTCT CTGGGCACCCGGTCCCCTCTGCCCCACCCTCAGCCGCTCTTTGCTCCAGACCTGCCCCTC CCTCTAGAGGCTGCCTGGGCCTGTTCACGTGTTTTCCATCCCACATAAATACAGTATTCC CACTCTTATCTTACAACTCCCCCACCGCCCACTCTCCACCTCACTAGCTCCCCAATCCCT GACCCTTTGAGGCCCCCAGTGATCTCGACTCCCCCCTGGCCACAGACCCCCAGGGCATTG TGTTCACTGTACTCTGTGGGCAAGGATGGGTCCAGAAGACCCCACTTCAGGCACTAAGAG GGGCTGGACCTGGCGGCAGGAAGCCAAAGAGACTGGGCCTAGGCCAGGAGTTCCCAAATG TGAGGGGCGAGAAACAAGACAAGCTCCTCCCTTGAGAATTCCCTGTGGATTTTTAAAACA GATATTATTTTTATTATTATTGTGACAAAATGTTGATAAATGGATATTAAATAGAATAAG TCATAAAAAAAAAAAAAAAAAA |
Protein Sequence | >8742 : length: 249 MAARRSQRRRGRRGEPGTALLVPLALGLGLALACLGLLLAVVSLGSRASLSAQEPAQEEL VAEEDQDPSELNPQTEESQDPAPFLNRLVRPRRSAPKGRKTRARRAIAAHYEVHPRPGQD GAQAGVDGTVSGWEEARINSSSPLRYNRQIGEFIVTRAGLYYLYCQVHFDEGKAVYLKLD LLVDGVLALRCLEEFSATAASSLGPQLRLCQVSGLLALRPGSSLRIRTLPWAHLKAAPFL TYFGLFQVH |