| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8644 |
Name | AKR1C3 |
Synonym | DD3|DDX|HA1753|HAKRB|HAKRe|HSD17B5|PGFS|hluPGFS;aldo-keto reductase family 1, member C3;AKR1C3;aldo-keto reductase family 1, member C3 |
Definition | 3-alpha hydroxysteroid dehydrogenase, type II|3-alpha-HSD type II, brain|aldo-keto reductase family 1 member C3|aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)|chlordecone reductase homolog HAKRb|dihydrodiol dehydro |
Position | 10p15-p14 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Steroid hormone biosynthesis;KEGG PATHWAY;hsa00140 |
Pathway | estrogen biosynthesis;BioCyc;PWY66-380 |
Pathway | Metabolism of xenobiotics by cytochrome P450;KEGG PATHWAY;hsa00980 |
Pathway | androgen biosynthesis;BioCyc;PWY66-378 |
Pathway | Arachidonic acid metabolism;KEGG PATHWAY;hsa00590 |
Disease | lung cancer;GAD |
Disease | CANCER;GAD |
Disease | METABOLIC;GAD |
Disease | testosterone;GAD |
External Links | |
Links to Entrez Gene | 8644 |
Links to all GeneRIF Items | 8644 |
Links to iHOP | 8644 |
Sequence Information | |
Nucleotide Sequence | >8644 : length: 1251 GCCCATTGTTTTTGTAATCTCTGAGGAGAAGCAGCAGCAAACATTTGCTAGTCAGACAAG TGACAGGGAATGGATTCCAAACACCAGTGTGTAAAGCTAAATGATGGCCACTTCATGCCT GTATTGGGATTTGGCACCTATGCACCTCCAGAGGTTCCGAGAAGTAAAGCTTTGGAGGTC ACAAAATTAGCAATAGAAGCTGGGTTCCGCCATATAGATTCTGCTCATTTATACAATAAT GAGGAGCAGGTTGGACTGGCCATCCGAAGCAAGATTGCAGATGGCAGTGTGAAGAGAGAA GACATATTCTACACTTCAAAGCTTTGGTCCACTTTTCATCGACCAGAGTTGGTCCGACCA GCCTTGGAAAACTCACTGAAGAAAGCTCAATTGGACTATGTTGACCTCTATCTTATTCAT TCTCCAATGTCTCTAAAGCCAGGTGAGGAACTTTCACCAACAGATGAAAATGGAAAAGTA ATATTTGACATAGTGGATCTCTGTACCACCTGGGAGGCCATGGAGAAGTGTAAGGATGCA GGATTGGCCAAGTCCATTGGGGTGTCAAACTTCAACCGCAGGCAGCTGGAGATGATCCTC AACAAGCCAGGACTCAAGTACAAGCCTGTCTGCAACCAGGTAGAATGTCATCCGTATTTC AACCGGAGTAAATTGCTAGATTTCTGCAAGTCGAAAGATATTGTTCTGGTTGCCTATAGT GCTCTGGGATCTCAACGAGACAAACGATGGGTGGACCCGAACTCCCCGGTGCTCTTGGAG GACCCAGTCCTTTGTGCCTTGGCAAAAAAGCACAAGCGAACCCCAGCCCTGATTGCCCTG CGCTACCAGCTGCAGCGTGGGGTTGTGGTCCTGGCCAAGAGCTACAATGAGCAGCGCATC AGACAGAACGTGCAGGTTTTTGAGTTCCAGTTGACTGCAGAGGACATGAAAGCCATAGAT GGCCTAGACAGAAATCTCCACTATTTTAACAGTGATAGTTTTGCTAGCCACCCTAATTAT CCATATTCAGATGAATATTAACATGGAGGGCTTTGCCTGATGTCTACCAGAAGCCCTGTG TGTGGATGGTGACGCAGAGGACGTCTCTATGCCGGTGACTGGACATATCACCTCTACTTA AATCCGTCCTGTTTAGCGACTTCAGTCAACTACAGCTGAGTCCATAGGCCAGAAAGACAA TAAATTTTTATCATTTTGAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >8644 : length: 323 MDSKHQCLKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD RNLHYFNSDSFASHPNYPYSDEY |