| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8491 |
Name | MAP4K3 |
Synonym | GLK|MAPKKKK3|MEKKK 3|MEKKK3|RAB8IPL1;mitogen-activated protein kinase kinase kinase kinase 3;MAP4K3;mitogen-activated protein kinase kinase kinase kinase 3 |
Definition | MAPK/ERK kinase kinase kinase 3|MEK kinase kinase 3|germinal center kinase-like kinase|germinal center kinase-related protein kinase |
Position | 2p22.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | mapkinase signaling pathway;PID BioCarta;100113 |
External Links | |
Links to Entrez Gene | 8491 |
Links to all GeneRIF Items | 8491 |
Links to iHOP | 8491 |
Sequence Information | |
Nucleotide Sequence | >8491 : length: 4387 AAGGGGAGGGGGAGGAGCGGCGAAAGCGGAAGCCATGTTGGAGTTTCACCCCGAGCGAGG GGCTGCGAGGGTTCTCCTCTCCTTGTGGGTGTGACCAGGTTCGGCGCGGCGGCGGGCCGC GGGGGGCGGGGACGATTGGCCGCTTGTCGTCGTCCGCAGCGGCGTGAGGGGAGCGGCGGC GGCGGCGGCGGCCGCAGCGTGGAGCCGGGTGATTGTGACCGCCGGGGGAGCCGGGAGCCG GCCGCGGCGCCCTCTCTCCGTGTGGCCCCCTGAGCGGCCCCCCTCCCCTGCCCGGGAGGG AGGCGGGGGGCACCTGGGGCCCGCCATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCC GCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTCTACAA GGCACGGAATGTTAACACTGGTGAATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGG AGAAGACTTTGCAGTTGTGCAGCAAGAAATTATTATGATGAAAGACTGTAAACACCCAAA TATTGTTGCTTATTTTGGAAGCTATCTCAGGCGAGATAAGCTTTGGATTTGCATGGAGTT TTGTGGAGGTGGTTCTTTACAGGATATTTATCACGTAACTGGACCTCTGTCAGAACTGCA AATTGCATATGTTAGCAGAGAAACACTGCAGGGATTATATTATCTTCACAGTAAAGGAAA AATGCACAGAGATATAAAGGGAGCTAACATTCTATTAACGGATAATGGTCATGTGAAATT GGCTGATTTTGGAGTATCTGCACAGATAACAGCTACAATTGCCAAACGGAAGTCTTTCAT TGGCACACCATATTGGATGGCTCCAGAAGTTGCAGCTGTTGAGAGGAAGGGGGGTTACAA TCAACTCTGTGATCTCTGGGCAGTGGGAATCACTGCCATAGAACTTGCAGAGCTTCAGCC TCCTATGTTTGACTTACACCCAATGAGAGCATTATTTCTAATGACAAAAAGCAATTTTCA GCCTCCTAAACTAAAGGATAAAATGAAATGGTCAAATAGTTTTCATCACTTTGTGAAAAT GGCACTTACCAAAAATCCGAAAAAAAGACCTACTGCTGAAAAATTATTACAGCATCCTTT TGTAACACAACATTTGACACGGTCTTTGGCAATCGAGCTGTTGGATAAAGTAAATAATCC AGATCATTCCACTTACCATGATTTCGATGATGATGATCCTGAGCCTCTTGTTGCTGTACC ACATAGAATTCACTCAACAAGTAGAAACGTGAGAGAAGAAAAAACACGCTCAGAGATAAC CTTTGGCCAAGTGAAATTTGATCCACCCTTAAGAAAGGAGACAGAACCACATCATGAACT TCCCGACAGTGATGGTTTTTTGGACAGTTCAGAAGAAATATACTACACTGCAAGATCTAA TCTGGATCTGCAACTGGAATATGGACAAGGACACCAAGGTGGTTACTTTTTAGGTGCAAA CAAGAGTCTTCTCAAGTCTGTTGAAGAAGAATTGCATCAGCGAGGACACGTCGCACATTT AGAAGATGATGAAGGAGATGATGATGAATCTAAACACTCAACTCTGAAAGCAAAAATTCC ACCTCCTTTGCCACCAAAGCCTAAGTCTATCTTCATACCACAGGAAATGCATTCTACTGA GGATGAAAATCAAGGAACAATCAAGAGATGTCCCATGTCAGGGAGCCCAGCAAAGCCATC CCAAGTTCCACCTAGACCACCACCTCCCAGATTACCCCCACACAAACCTGTTGCCTTAGG AAATGGAATGAGCTCCTTCCAGTTAAATGGTGAACGAGATGGCTCATTATGTCAACAACA GAATGAACATAGAGGCACAAACCTTTCAAGAAAAGAAAAGAAAGATGTACCAAAGCCTAT TAGTAATGGTCTTCCTCCAACACCTAAAGTGCATATGGGTGCATGTTTTTCAAAAGTTTT TAATGGGTGTCCCTTGAAAATTCACTGTGCATCATCATGGATAAACCCAGATACAAGAGA TCAGTACTTGATATTTGGTGCCGAAGAAGGGATTTATACCCTCAATCTTAATGAACTTCA TGAAACATCAATGGAACAGCTATTCCCTCGAAGGTGTACATGGTTGTATGTAATGAACAA TTGCTTGCTATCAATATCTGGTAAAGCTTCTCAGCTTTATTCCCATAATTTACCAGGGCT TTTTGATTATGCAAGACAAATGCAAAAGTTACCTGTTGCTATTCCAGCACACAAACTCCC TGACAGAATACTGCCAAGGAAATTTTCTGTATCAGCAAAAATCCCTGAAACCAAATGGTG CCAGAAGTGTTGTGTTGTAAGAAATCCTTACACGGGCCATAAATACCTATGTGGAGCACT TCAGACTAGCATTGTTCTATTAGAATGGGTTGAACCAATGCAGAAATTTATGTTAATTAA GCACATAGATTTTCCTATACCATGTCCACTTAGAATGTTTGAAATGCTGGTAGTTCCTGA ACAGGAGTACCCTTTAGTTTGTGTTGGTGTCAGTAGAGGTAGAGACTTCAACCAAGTGGT TCGATTTGAGACGGTCAATCCAAATTCTACCTCTTCATGGTTTACAGAATCAGATACCCC ACAGACAAATGTTACTCATGTAACCCAACTGGAGAGAGATACCATCCTTGTATGCTTGGA CTGTTGTATAAAAATAGTAAATCTCCAAGGAAGATTAAAATCTAGCAGGAAATTGTCATC AGAACTCACCTTTGATTTCCAGATTGAATCAATAGTAATTGAGCTGTTCTTGCCTGCTAG TGTGCCTACAAGACAGTGTGCTAGCTTTCTGGAAACATGGAATGCAAGGTAGAAGTTTTA GATCTAATGAGGTAACACAAGAAATTTCAGATAGCACAAGAATTTTCAGGCTGCTTGGAT CTGACAGGGTCGTGGTTTTGGAAAGTAGGCCAACTGATAACCCCACAGCAAATAGCAATT TGTACATCCTGGCGGGTCATGAAAACAGTTACTGAGAATTGTTGTGCTTTGACAGTTAAC TCTAGAAAGAAAGAACACTACCACTGCAACATTAATGGATGCTTGAAGCTGTACAAAAGC TGCAGTAACCTGTCTTCAGTTACTTTGTAATTTATTGTGGCATGAGATAAGATGGGGAAA ATTTTGTTTTAAGTGGTATGGATATATTTAGCATATTGAACCACACAAGTGCTTAATTCA TTGTTATGTAATCTTTGTACATATAGGCAGTATTTTTTCTGTGAAACTTCATATTGCTGA AGACATACACTAAGAATTTATGTAGATAATGTACTTTTATGAGATGTACAAGTAAGTGTC TTATCTGTACAGATGTAAATGTTGATGAAAATGCAATTGGGGTTAATATTTTAAGAATTC TTTAGTATATTCTTGGGTGTGGCTATATTACAAAATGGGATGCTGGCAATGAAACAATAC ATTTAACACTATTGTATTTTTATTATATGTAATTTAGTAATATGAATATAAATCTTGTAA CTTTTAAAATTGTAATGGAGGCTGTAATCATTTTATAATCTTTTTAATTTTAATGCAAGT ACACTGGTGTTTATATTTGCACAAAGTATTGATATGTGATGTATTAAGTCACAAAAGTAA GCTGTGACATTGTCTATAAGCATTTGGCTCCACAAATGTATTTGGATTGTTTTCTATGTG AAGCAAACCAATTATAATTAACCACATGTTGTAGTAACTGGTCTTTTTATATTTAAGCAG AATCCTGTAAGATTGCTTGTCTTTGCTTAAAAACAATACCTTTGAACATTTTTGAATCAC AGAATAGCGGTACCATGATAGAATACTGCAATTGTGGTCAGAATTACAGTATGCACAAAG AATTAATTAGCATTATTAAAGAGTCCTCACTAAACATTTCATATGATCACACTGAAGAAC TGTAACATTCCATAGAGTGAAGTGGTTCAAATTTCTCTTGGAATTTTTACTTTTGTTGGC CTTATTTTATGATCCTTTTCATATTTCTTTTGACTTAGAGTATTAATACATGGCCAAAAT AATTTAGTTACTACCTCATACAAACAATATAATGGTTACTACACATCACAGGAACTTAGT TTTGGTTTAAGTCATTTTTGATTGCTTTTTTCCAATGGAATATGTATATACCAGGTTTTA GCAAAATGCACACTTTTGGCTCTTTTTGGTATATGTTCTTTATATTTTAATGTGAGTATA TACACTAAGAACAAACTAAATTGTGATTTATGATCTTCATTTATTTTAATGATAATGGTT TTAAAATATGTTCCTGATTGTACATATTGTAAAATAAACATGTTTTTTAACATGCTGTTG TATAGTA |
Protein Sequence | >8491 : length: 894 MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQ EIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRET LQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAP EVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKM KWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDF DDDDPEPLVAVPHRIHSTSRNVREEKTRSEITFGQVKFDPPLRKETEPHHELPDSDGFLD SSEEIYYTARSNLDLQLEYGQGHQGGYFLGANKSLLKSVEEELHQRGHVAHLEDDEGDDD ESKHSTLKAKIPPPLPPKPKSIFIPQEMHSTEDENQGTIKRCPMSGSPAKPSQVPPRPPP PRLPPHKPVALGNGMSSFQLNGERDGSLCQQQNEHRGTNLSRKEKKDVPKPISNGLPPTP KVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLF PRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKF SVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPC PLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDTPQTNVTHVT QLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQG RSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY |