| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 84876 |
Name | ORAI1 |
Synonym | CRACM1|IMD9|ORAT1|TAM2|TMEM142A;ORAI calcium release-activated calcium modulator 1;ORAI1;ORAI calcium release-activated calcium modulator 1 |
Definition | calcium release-activated calcium channel protein 1|calcium release-activated calcium modulator 1|protein orai-1|transmembrane protein 142A |
Position | 12q24.31 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | TCR signaling in naive CD4+ T cells;PID Curated;200022 |
Pathway | TCR signaling in naive CD8+ T cells;PID Curated;200062 |
Pathway | Hemostasis;Reactome;REACT:604 |
Disease | Immune dysfunction with T-cell inactivation due to calcium entry defect 1;OMIM |
External Links | |
Links to Entrez Gene | 84876 |
Links to all GeneRIF Items | 84876 |
Links to iHOP | 84876 |
Sequence Information | |
Nucleotide Sequence | >84876 : length: 1496 GCCGCCCGGGGGCTTTTGCCAGCGGCGCCGCGGGCCTGCGTGCTGGGGCAGCGGGCACTT CTTCGACCTCGTCCTCCTCGTCCTGTGCGGCCGGCCGGGTGAGGCCGGGCCCGCGTAGGG GGCAGTCGGCGGCTGCCTCCGGCGGAGGTGCCTCGCGGCGCCCGGGCCGGCCCGCGCCTC GGCGGCGTGCTCCATGCATCCGGAGCCCGCCCCGCCCCCGAGCCGCAGCAGTCCCGAGCT TCCCCCAAGCGGCGGCAGCACCACCAGCGGCAGCCGCCGGAGCCGCCGCCGCAGCGGGGA CGGGGAGCCCCCGGGGGCCCCGCCACCGCCGCCGTCCGCCGTCACCTACCCGGACTGGAT CGGCCAGAGTTACTCCGAGGTGATGAGCCTCAACGAGCACTCCATGCAGGCGCTGTCCTG GCGCAAGCTCTACTTGAGCCGCGCCAAGCTTAAAGCCTCCAGCCGGACCTCGGCTCTGCT CTCCGGCTTCGCCATGGTGGCAATGGTGGAGGTGCAGCTGGACGCTGACCACGACTACCC ACCGGGGCTGCTCATCGCCTTCAGTGCCTGCACCACAGTGCTGGTGGCTGTGCACCTGTT TGCGCTCATGATCAGCACCTGCATCCTGCCCAACATCGAGGCGGTGAGCAACGTGCACAA TCTCAACTCGGTCAAGGAGTCCCCCCATGAGCGCATGCACCGCCACATCGAGCTGGCCTG GGCCTTCTCCACCGTCATCGGCACGCTGCTCTTCCTAGCTGAGGTGGTGCTGCTCTGCTG GGTCAAGTTCTTGCCCCTCAAGAAGCAGCCAGGCCAGCCAAGGCCCACCAGCAAGCCCCC CGCCAGTGGCGCAGCAGCCAACGTCAGCACCAGCGGCATCACCCCGGGCCAGGCAGCTGC CATCGCCTCGACCACCATCATGGTGCCCTTCGGCCTGATCTTTATCGTCTTCGCCGTCCA CTTCTACCGCTCACTGGTTAGCCATAAGACTGACCGACAGTTCCAGGAGCTCAACGAGCT GGCGGAGTTTGCCCGCTTACAGGACCAGCTGGACCACAGAGGGGACCACCCCCTGACGCC CGGCAGCCACTATGCCTAGGCCCATGTGGTCTGGGCCCTTCCAGTGCTTTGGCCTTACGC CCTTCCCCTTGACCTTGTCCTGCCCCAGCCTCACGGACAGCCTGCGCAGGGGGCTGGGCT TCAGCAAGGGGCAGAGCATGGAGGGAAGAGGATTTTTATAAGAGAAATTTCTGCACTTTG AAACTGTCCTCTAAGAGAATAAGCATTTCCTGTTCTTCCAGCTCCAGGTCCACCTCCTGT TGGGAGGCGGTGGGGGGCCAAAGTGGGGCCACACACTCGCTGTGTCCCCTCTCCTCCCCT GTGCCAGTGCCACCTGGGTGCCTCCTCCTGTCCTGTCCGTCTCAACCTCCCTCCCGTCCA GCATTGAGTGTGTACATGTGTGTGTGACACATAAATATACTCATAAGGACACCTCC |
Protein Sequence | >84876 : length: 301 MHPEPAPPPSRSSPELPPSGGSTTSGSRRSRRRSGDGEPPGAPPPPPSAVTYPDWIGQSY SEVMSLNEHSMQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDADHDYPPGLL IAFSACTTVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFST VIGTLLFLAEVVLLCWVKFLPLKKQPGQPRPTSKPPASGAAANVSTSGITPGQAAAIAST TIMVPFGLIFIVFAVHFYRSLVSHKTDRQFQELNELAEFARLQDQLDHRGDHPLTPGSHY A |