| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8454 |
Name | CUL1 |
Synonym | cullin 1;CUL1;cullin 1 |
Definition | CUL-1|cullin-1 |
Position | 7q36.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Pathway | Degradation of beta-catenin by the destruction complex;PID Reactome;500310 |
Pathway | Regulation of Wnt-mediated beta catenin signaling and target gene transcription;PID Curated;200106 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | Canonical Wnt signaling pathway;PID Curated;200064 |
Pathway | e2f1 destruction pathway;PID BioCarta;100034 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | SCF-beta-TrCP mediated degradation of Emi1;PID Reactome;500393 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Signaling by Wnt;Reactome;REACT:11045 |
Pathway | Interleukin-1 signaling;PID Reactome;500490 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Pathway | cyclin e destruction pathway;PID BioCarta;100166 |
Pathway | TGF-beta signaling pathway;KEGG PATHWAY;hsa04350 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Pathway | Circadian rhythm - mammal;KEGG PATHWAY;hsa04710 |
Pathway | Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141 |
Pathway | regulation of p27 phosphorylation during cell cycle progression;PID BioCarta;100087 |
External Links | |
Links to Entrez Gene | 8454 |
Links to all GeneRIF Items | 8454 |
Links to iHOP | 8454 |
Sequence Information | |
Nucleotide Sequence | >8454 : length: 3245 AGGTAGAAGCTTCCCCACGCGAGCGGGGGCCTCGGCCGCGGAAGGGGCGCCCCCGGGGCC GCCGGCAGCGGCGAGCGGGCGGGAGGGAGCTTTCCGGGCCCCTCCCGCGCCTCGGGCTGG CGGGGCGATGGCGACGACGGTTTCCCGGCTCCCCCGCCCCGGACGCCGATGGCGGTGCGT TCCGGCCCTCCCCCAACAGCTTCTCCCCCGCGGTCGCCGGAGCCGGTTTGCCTGCAATGA GATTTCATTCTCTACATTTAAAGGACATCCTTTCTGAGCTGCTGTGAATAAATTTGGAAT GGTACTGTATATTTTCATCTAATGGAGAACTAGCTGTACTTTGAATAAGGATTGCTGCAC TGGACGACTTTAGAACATCCCTCACAATGTCGTCAACCCGGAGCCAGAACCCCCACGGCC TGAAGCAGATTGGCCTGGACCAGATCTGGGACGACCTCAGAGCCGGCATCCAGCAGGTGT ACACACGGCAGAGCATGGCCAAGTCCAGATATATGGAGCTCTACACTCATGTTTATAACT ACTGTACTAGTGTTCACCAGTCAAACCAAGCACGAGGAGCTGGAGTTCCTCCTTCTAAGT CGAAAAAGGGGCAGACACCTGGAGGAGCTCAGTTTGTTGGCCTGGAATTATATAAACGAC TTAAGGAATTTTTGAAGAATTACTTGACAAATCTTCTTAAGGATGGAGAAGATTTGATGG ATGAGAGTGTACTGAAATTCTACACTCAACAATGGGAAGATTATCGATTTTCAAGCAAAG TGCTGAATGGAATTTGTGCCTACCTCAATAGACATTGGGTTCGCCGTGAATGTGACGAAG GACGAAAAGGAATATATGAAATCTATTCGCTTGCATTGGTGACTTGGAGAGACTGTCTGT TCAGGCCACTGAATAAACAGGTAACAAATGCTGTTTTAAAGCTGATTGAAAAGGAAAGGA ATGGTGAAACCATCAATACAAGATTGATTAGTGGAGTTGTACAGTCTTACGTGGAATTGG GGCTGAATGAAGATGATGCATTTGCAAAGGGCCCTACGTTAACAGTGTATAAAGAATCCT TTGAATCTCAATTTTTGGCTGACACAGAGAGATTTTATACCAGAGAGAGTACTGAATTCT TGCAGCAGAACCCAGTTACTGAATATATGAAAAAGGCAGAGGCTCGTCTGCTTGAGGAAC AACGAAGAGTTCAGGTTTACCTTCATGAAAGCACACAAGATGAATTAGCAAGGAAATGTG AACAAGTCCTCATTGAAAAACACTTGGAAATTTTCCACACAGAATTTCAGAATTTATTGG ATGCTGACAAAAATGAAGATTTGGGACGCATGTATAATCTTGTATCTAGAATCCAGGATG GCCTAGGAGAATTGAAAAAACTGTTGGAGACACACATTCATAATCAGGGTCTTGCAGCCA TTGAAAAGTGTGGAGAAGCTGCTTTAAATGACCCCAAAATGTATGTACAGACAGTGCTTG ATGTTCATAAAAAATACAATGCCCTGGTAATGTCTGCATTCAACAATGACGCTGGCTTTG TGGCTGCTCTTGATAAGGCTTGTGGTCGCTTCATAAACAACAACGCGGTTACCAAGATGG CCCAATCATCCAGTAAATCCCCTGAGTTGCTGGCTCGATACTGTGACTCCTTGTTGAAGA AAAGTTCCAAGAACCCAGAGGAGGCAGAACTAGAAGACACACTCAATCAAGTGATGGTTG TCTTCAAGTACATAGAAGACAAAGACGTATTTCAGAAGTTCTATGCGAAGATGCTCGCCA AGAGGCTCGTCCACCAGAACAGTGCAAGTGACGATGCCGAAGCCAGCATGATCTCCAAGT TAAAGCAAGCTTGCGGGTTCGAGTACACCTCTAAACTTCAGCGCATGTTTCAAGACATTG GCGTGAGCAAAGATCTGAACGAGCAATTCAAAAAGCACTTGACAAACTCAGAACCCCTAG ACTTGGATTTCAGCATTCAAGTGCTGAGCTCCGGGTCCTGGCCCTTCCAGCAGTCTTGTA CATTTGCCTTGCCGTCAGAGTTGGAACGTAGTTATCAGCGATTCACAGCTTTCTACGCCA GCCGCCACAGTGGCCGAAAATTGACGTGGTTATATCAGTTGTCTAAAGGAGAATTGGTAA CTAACTGCTTCAAAAACAGATATACTTTGCAGGCGTCGACATTCCAGATGGCTATCCTGC TTCAGTACAACACGGAAGATGCCTACACTGTGCAGCAGCTGACCGACAGCACTCAAATTA AAATGGACATTTTGGCGCAAGTTTTACAGATTTTATTAAAGTCGAAGCTATTGGTCTTGG AAGATGAAAATGCAAATGTTGATGAGGTGGAATTGAAGCCAGATACCTTAATAAAATTAT ATCTTGGTTATAAAAATAAGAAATTAAGGGTTAACATCAATGTGCCAATGAAAACCGAAC AGAAGCAGGAACAAGAAACCACACACAAAAACATCGAGGAAGACCGCAAACTACTGATTC AGGCGGCCATCGTGAGAATCATGAAGATGAGGAAGGTTCTGAAACACCAGCAGTTACTTG GCGAGGTCCTCACTCAGCTGTCCTCCAGGTTCAAACCTCGAGTCCCTGTGATCAAGAAAT GCATTGACATTCTAATTGAGAAAGAATATTTGGAGCGAGTGGATGGTGAAAAGGACACCT ACAGTTACTTGGCTTAACCCTTCTGGAAGGGTCTGACTGTGTGACCCGCAGCAAATAGTT CATGTTGGAAAGAATGAAAACAACTCAAGTTCATAGCAGCCAGCCTGCCGCCATTGGACC TCCCTTTTAAAAACTGAGACCAAGACTCCCATCAGCTGGTCTCGGATTTACATCGGAACT GCTCAGGATTGATACATTTCAAGTCTGTAAATACGGACACCAACGCCATTTACCCTAATT TAAGAACAGCGGGGACTGACCCTCCGTGCCGAGGGCTGCATGCTACCGCACTAAGTCAAT ACATGGGCTCCCCGATTCGCAGCTGTCGTCTTGGCAGCACTTGTCACGTTGGCAGCACTT TGAGAGCAAGTCTGAGTGGACCCACATGTAACCTGCTATGAAAACCATTTGTATAGTGTG TTTCATTTTTTAATGTGTGAAAATAAAGAAAATTAAAGGATTTCTGTACAAGTCGCATTG GGTTTTGTTTTAAGTTTTACTAATTTCTATATGTAAATAAAAGATATAATGATTGTGCAA ATTTA |
Protein Sequence | >8454 : length: 776 MSSTRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSN QARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLKFYT QQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVT NAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADT ERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHL EIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAAL NDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPE LLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSA SDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVL SSGSWPFQQSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYT LQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDE VELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMK MRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA |