| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 840 |
Name | CASP7 |
Synonym | CASP-7|CMH-1|ICE-LAP3|LICE2|MCH3;caspase 7, apoptosis-related cysteine peptidase;CASP7;caspase 7, apoptosis-related cysteine peptidase |
Definition | ICE-like apoptotic protease 3|apoptotic protease MCH-3|caspase 7, apoptosis-related cysteine protease|caspase-7 |
Position | 10q25 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | apoptotic signaling in response to dna damage;PID BioCarta;100204 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | fas signaling pathway (cd95);PID BioCarta;100167 |
Pathway | Caspase cascade in apoptosis;PID Curated;200148 |
Pathway | b cell survival pathway;PID BioCarta;100228 |
Pathway | Apoptotic cleavage of cellular proteins;PID Reactome;500270 |
Pathway | hiv-1 nef: negative effector of fas and tnf;PID BioCarta;100144 |
Pathway | induction of apoptosis through dr3 and dr4/5 death receptors;PID BioCarta;100189 |
Pathway | HIV-1 Nef: Negative effector of Fas and TNF-alpha;PID Curated;200133 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | caspase cascade in apoptosis;PID BioCarta;100218 |
Pathway | Alzheimer's disease;KEGG PATHWAY;hsa05010 |
Pathway | apoptotic dna-fragmentation and tissue homeostasis;PID BioCarta;100187 |
Pathway | west nile virus;PID BioCarta;100001 |
Pathway | Activation of caspases through apoptosome-mediated cleavage;PID Reactome;500267 |
Pathway | FAS signaling pathway;PANTHER;P00020 |
Pathway | trefoil factors initiate mucosal healing;PID BioCarta;100018 |
Pathway | regulation of cell cycle progression by plk3;PID BioCarta;100068 |
Disease | diabetes, type 1;GAD |
Disease | CHEMDEPENDENCY;GAD |
Disease | IMMUNE;GAD |
Disease | smoking cessation;GAD |
Disease | Lymphoma;FunDO |
Disease | Periodontitis;FunDO |
Disease | Melanoma;FunDO |
Disease | Stomach cancer;FunDO |
External Links | |
Links to Entrez Gene | 840 |
Links to all GeneRIF Items | 840 |
Links to iHOP | 840 |
Sequence Information | |
Nucleotide Sequence | >840 : length: 2714 CCCGCGCGCGGGCTCAACTTTGTAGAGCGAGGGGCCAACTTGGCAGAGCGCGCGGCCAGC TTTGCAGAGAGCGCCCTCCAGGGACTATGCGTGCGGGGACACGGGTCGCTTTGGGCTCTT CCACCCCTGCGGAGCGCACTACCCCGAGCCAGGGGCGGTGCAAGCCCCGCCCGGCCCTAC CCAGGGCGGCTCCTCCCTCCGCAGCGCCGAGACTTTTAGTTTCGCTTTCGCTAAAGGGGC CCCAGACCCTTGCTGCGGAGCGACGGAGAGAGACTGTGCCAGTCCCAGCCGCCCTACCGC CGTGGGAACGATGCTGTAATGGACTGTGTTGGTTGGCCTCCAGGCAGGAAGTGGCACTTG GAAAAGAACACCAGCTGCGGTGGTAGCAGTGGGATTTGTGCTTCTTATGTTACCCAGATG GCAGATGATCAGGGCTGTATTGAAGAGCAGGGGGTTGAGGATTCAGCAAATGAAGATTCA GTGGATGCTAAGCCAGACCGGTCCTCGTTTGTACCGTCCCTCTTCAGTAAGAAGAAGAAA AATGTCACCATGCGATCCATCAAGACCACCCGGGACCGAGTGCCTACATATCAGTACAAC ATGAATTTTGAAAAGCTGGGCAAATGCATCATAATAAACAACAAGAACTTTGATAAAGTG ACAGGTATGGGCGTTCGAAACGGAACAGACAAAGATGCCGAGGCGCTCTTCAAGTGCTTC CGAAGCCTGGGTTTTGACGTGATTGTCTATAATGACTGCTCTTGTGCCAAGATGCAAGAT CTGCTTAAAAAAGCTTCTGAAGAGGACCATACAAATGCCGCCTGCTTCGCCTGCATCCTC TTAAGCCATGGAGAAGAAAATGTAATTTATGGGAAAGATGGTGTCACACCAATAAAGGAT TTGACAGCCCACTTTAGGGGGGATAGATGCAAAACCCTTTTAGAGAAACCCAAACTCTTC TTCATTCAGGCTTGCCGAGGGACCGAGCTTGATGATGGCATCCAGGCCGACTCGGGGCCC ATCAATGACACAGATGCTAATCCTCGATACAAGATCCCAGTGGAAGCTGACTTCCTCTTC GCCTATTCCACGGTTCCAGGCTATTACTCGTGGAGGAGCCCAGGAAGAGGCTCCTGGTTT GTGCAAGCCCTCTGCTCCATCCTGGAGGAGCACGGAAAAGACCTGGAAATCATGCAGATC CTCACCAGGGTGAATGACAGAGTTGCCAGGCACTTTGAGTCTCAGTCTGATGACCCACAC TTCCATGAGAAGAAGCAGATCCCCTGTGTGGTCTCCATGCTCACCAAGGAACTCTACTTC AGTCAATAGCCATATCAGGGGTACATTCTAGCTGAGAAGCAATGGGTCACTCATTAATGA ATCACATTTTTTTATGCTCTTGAAATATTCAGAAATTCTCCAGGATTTTAATTTCAGGAA AATGTATTGATTCAACAGGGAAGAAACTTTCTGGTGCTGTCTTTTGTTCTCTGAATTTTC AGAGACTTTTTTTATAATGTTATTCATTTGGTGACTGTGTAACTTTCTCTTAAGATTAAT TTTCTCTTTGTATGTCTGTTACCTTGTTAATAGACTTAATACATGCAACAGAAGTGACTT CTGGAGAAAGCTCATGGCTGTGTCCACTGCAATTGGTGGTAACAGTGGTAGAGTCATGTT TGCACTTGGCAAAAAGAATCCCAATGTTTGACAAAACACAGCCAAGGGGATATTTACTGC TCTTTATTGCAGAATGTGGGTATTGAGTGTGATTTGAATGATTTTTCATTGGCTTAGGGC AGATTTTCATGCAAAAGTTCTCATATGAGTTAGAGGAGAAAAAGCTTAATGATTCTGATA TGTATCCATCAGGATCCAGTCTGGAAAACAGAAACCATTCTAGGTGTTTCAACAGAGGGA GTTTAATACAGGAAATTGACTTACATAGATGATAAAAGAGAAGCCAAACAGCAAGAAGCT GTTACCACACCCAGGGCTATGAGGATAATGGGAAGAGGTTTGGTTTCCTGTGTCCAGTAG TGGGATCATCCAGAGGAGCTGGAACCATGGTGGGGGCTGCCTAGTGGGAGTTAGGACCAC CAATGGATTGTGGAAAATGGAGCCATGACAAGAACAAAGCCACTGACTGAGATGGAGTGA GCTGAGACAGATAAGAGAATACCTTGGTCTCACCTATCCTGCCCTCACATCTTCCACCAG CACCTTACTGCCCAGGCCTATCTGGAAGCCACCTCACCAAGGACCTTGGAAGAGCAAGGG ACAGTGAGGCAGGAGAAGAACAAGAAATGGATGTAAGCCTGGCCCATAATGTGAACATAA GTAATCACTAATGCTCAACAATTTATCCATTCAATCATTTATTCATTGGGTTGTCAGATA GTCTATGTATGTGTAAAACAATCTGTTTTGGCTTTATGTGCAAAATCTGTTATAGCTTTA AAATATATCTGGAACTTTTTAGATTATTCCAAGCCTTATTTTGAGTAAATATTTGTTACT TTTAGTTCTATAAGTGAGGAAGAGTTTATGGCAAAGATTTTTGGCACTTTGTTTTCAAGA TGGTGTTATCTTTTGAATTCTTGATAAATGACTGTTTTTTTCTGCCTAATAGTAACTGGT TAAAAAACAAATGTTCATATTTATTGATTAAAAATGTGGTTGCTTAATTCCTAACCAGAA AAAAAAAAAAAAAA |
Protein Sequence | >840 : length: 388 MRAGTRVALGSSTPAERTTPSQGRCKPRPALPRAAPPSAAPRLLVSLSLKGPQTLAAERR RETVPVPAALPPWERWQMIRAVLKSRGLRIQQMKIQWMLSQTGPRLYRPSSAPDSGTLYF TSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAE ALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDG VTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPV EADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFES QSDDPHFHEKKQIPCVVSMLTKELYFSQ |