| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 824 |
Name | CAPN2 |
Synonym | CANP2|CANPL2|CANPml|mCANP;calpain 2, (m/II) large subunit;CAPN2;calpain 2, (m/II) large subunit |
Definition | CANP 2|M-calpain|calcium-activated neutral proteinase 2|calpain 2, large [catalytic] subunit|calpain 2, large subunit|calpain M-type|calpain large polypeptide L2|calpain, large polypeptide L2|calpain-2 catalytic subunit|calpain-2 large subunit|millimolar- |
Position | 1q41-q42 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | mcalpain and friends in cell motility;PID BioCarta;100111 |
Pathway | Alzheimer's disease;KEGG PATHWAY;hsa05010 |
Pathway | role of mef2d in t-cell apoptosis;PID BioCarta;100109 |
Pathway | Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141 |
Pathway | Huntington disease;PANTHER;P00029 |
Pathway | Signaling events mediated by focal adhesion kinase;PID Curated;200192 |
Disease | Malaria;FunDO |
Disease | Breast cancer;FunDO |
Disease | Muscular dystrophy;FunDO |
Disease | Neurodegenerative disorder;FunDO |
External Links | |
Links to Entrez Gene | 824 |
Links to all GeneRIF Items | 824 |
Links to iHOP | 824 |
Sequence Information | |
Nucleotide Sequence | >824 : length: 3492 CAGGCCGCAGGATGGCCTGGTCCCGGGCCGGGAGCCCAGCAGGCCGGGAGCGGCTGAGGC CACACCCCGCGGGCCGGGCCGCTTCCCTCCGGTGAATCATCGCTCGCAGCGGCGGCGCCC GCAGTGGCCGCAGCAGCGCGCCGGGCCCTGGCCGCGCCCCAGCCGAGCGCAGCGCGGAGT CGCCCCGACCTTTCTCTGCGCAGTACGGCCGCCGGGACCGCAGCATGGCGGGCATCGCGG CCAAGCTGGCGAAGGACCGGGAGGCGGCCGAGGGGCTGGGCTCCCACGAGAGGGCCATCA AGTACCTCAACCAGGACTACGAGGCGCTGCGGAACGAGTGCCTGGAGGCCGGGACGCTCT TCCAGGACCCGTCCTTCCCGGCCATCCCCTCGGCCCTGGGCTTCAAGGAGTTGGGGCCCT ACTCCAGCAAAACCCGGGGCATCGAGTGGAAGCGCCCCACGGAGATCTGCGCTGACCCCC AGTTTATCATTGGAGGAGCCACCCGCACAGACATCTGCCAAGGAGCCCTGGGTGACTGCT GGCTGCTGGCAGCCATTGCCTCCCTCACCTTGAATGAAGAAATCCTGGCTCGAGTCGTCC CCCTAAACCAGAGCTTCCAGGAAAACTATGCAGGGATCTTTCACTTCCAGTTCTGGCAAT ACGGCGAGTGGGTGGAGGTGGTGGTGGATGACAGGCTGCCCACCAAGGACGGGGAGCTGC TCTTTGTGCATTCAGCCGAAGGGAGCGAGTTCTGGAGCGCCCTGCTGGAGAAGGCATACG CCAAGATCAACGGATGCTATGAAGCGCTATCAGGGGGTGCCACCACTGAGGGCTTCGAAG ACTTCACCGGAGGCATTGCTGAGTGGTATGAGTTGAAGAAGCCCCCTCCCAACCTGTTCA AGATCATCCAGAAAGCTCTGCAAAAAGGCTCTCTCCTTGGCTGCTCCATCGACATCACCA GCGCCGCGGACTCGGAGGCCATCACGTTTCAGAAGCTGGTGAAGGGGCACGCGTACTCGG TCACCGGAGCCGAGGAGGTTGAAAGTAACGGAAGCCTACAGAAACTGATCCGCATCCGAA ATCCCTGGGGAGAAGTGGAGTGGACAGGGCGGTGGAATGACAACTGCCCAAGCTGGAACA CTATAGACCCAGAGGAGAGGGAAAGGCTGACCAGACGGCATGAAGATGGAGAATTCTGGA TGTCTTTCAGTGACTTCCTGAGGCACTATTCCCGCCTGGAGATCTGTAACCTGACCCCAG ACACTCTCACCAGCGATACCTACAAGAAGTGGAAACTCACCAAAATGGATGGGAACTGGA GGCGGGGCTCCACCGCGGGAGGTTGCAGGAACTACCCGAACACATTCTGGATGAACCCTC AGTACCTGATCAAGCTGGAGGAGGAGGATGAGGACGAGGAGGATGGGGAGAGCGGCTGCA CCTTCCTGGTGGGGCTCATTCAGAAGCACCGACGGCGGCAGAGGAAGATGGGCGAGGACA TGCACACCATCGGCTTTGGCATCTATGAGGTTCCAGAGGAGTTAAGTGGGCAGACCAACA TCCACCTCAGCAAAAACTTCTTCCTGACGAATCGCGCCAGGGAGCGCTCAGACACCTTCA TCAACCTCCGGGAGGTGCTCAACCGCTTCAAGCTGCCGCCAGGAGAGTACATTCTCGTGC CTTCCACCTTCGAACCCAACAAGGATGGGGATTTCTGCATCCGGGTCTTTTCTGAAAAGA AAGCTGACTACCAAGCTGTCGATGATGAAATCGAGGCCAATCTTGAAGAGTTCGACATCA GCGAGGATGACATTGATGATGGATTCAGGAGACTGTTTGCCCAGTTGGCAGGAGAGGATG CGGAGATCTCTGCCTTTGAGCTGCAGACCATCCTGAGAAGGGTTCTAGCAAAGCGCCAAG ATATCAAGTCAGATGGCTTCAGCATCGAGACATGCAAAATTATGGTTGACATGCTAGATT CGGACGGGAGTGGCAAGCTGGGGCTGAAGGAGTTCTACATTCTCTGGACGAAGATTCAAA AATACCAAAAAATTTACCGAGAAATCGACGTTGACAGGTCTGGTACCATGAATTCCTATG AAATGCGGAAGGCATTAGAAGAAGCAGGTTTCAAGATGCCCTGTCAACTCCACCAAGTCA TCGTTGCTCGGTTTGCAGATGACCAGCTCATCATCGATTTTGATAATTTTGTTCGGTGTT TGGTTCGGCTGGAAACGCTATTCAAGATATTTAAGCAGCTGGATCCCGAGAATACTGGAA CAATAGAGCTCGACCTTATCTCTTGGCTCTGTTTCTCAGTACTTTGAAGTTATAACTAAT CTGCCTGAAGACTTCTCATGATGGAAAATCAGCCAAGGACTAAGCTTCCATAGAAATACA CTTTGTATCTGGACCTCAAAATTATGGGAACATTTACTTAAACGGATGATCATAGCTGAA AATAATGATACTGTCAATTTGAGATAGCAGAAGTTTCACACATCAAAGTAAAAGATTTGC ATATCATTATACTAAATGCAAATGAGTCGCTTAACCCTTGACAAGGTCAAAGAAAGCTTT AAATCTGTAAATAGTATACACTTTTTACTTTTACACACTTTCCTGTTCATAGCAATATTA AATCAGGAAAAAAAAATGCAGGGAGGTATTTAACAGCTGAGCAAAAACATTGAGTCGCTC TCAAAGGACACGAGGCCCTTGGCAGGGAATATTTAAAGCAACTTCAAGTTTAAAATGCAG CTGTTGATTCTACCAAACAACAGTCCAAGATTACCATTTCCCATGAGCCAACTGGGAAAC ATGGTATATCATGAAGTAATCTTGTCAAGGCATCTGGAGAGTCCAGGAGAGAAGACTCAC CTCTGTCGCTTGGGTTAAACAAGAGACAGGTTTTGTAGAATATTGATTGGTAATAGTAAA TCGTTCTCCTTACAATCAAGTTCTTGACCCTATTCGGCCTTATACATCTGGTCTTACAAA GACCAAAGGGATCCTGCGCTTGATCAACTGAACCAGTATGCCAAAACCAGGCATCCAATT TGTAAACCAATTATGATAAAGGACAAAATAAGCTGTTTGCCACCTCAAAACTTTATGAAC TTCACCACCACTAGTGTCTGTCCATGGAGTTAGAGGGGACATCACTTAGAAGTTCTTATA GAAAGGACACAAGTTTGTTTCCTGGCTTTACCTTGGGAAAATGCTAGCAACATTATAGAA ATTTTGCCTTGTTGCCTTATCTTCTTCCAAATGTACTGTTAAATAAAAATAAAGGGTTAC CCCATGCAATCACACCATGCCATGTTTTCCTTCCTGGAGGGCAGCCCCACAGGACGGTTT ATGAGCACACAATTATAGCTTGTTTCTACTTTAACAAGGTATGCTGCCTCTGTAAATTCA TGTATTCAAAGGAAAAGACACCTTGCCTATAATTAAAATGTGGAACTATAAAATTTTTTA AAATCCAAAAAA |
Protein Sequence | >824 : length: 700 MAGIAAKLAKDREAAEGLGSHERAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGF KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI LARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGC SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDN CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQR KMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPG EYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQ LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFD NFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL |