| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 80781 |
Name | COL18A1 |
Synonym | KNO|KNO1|KS;collagen, type XVIII, alpha 1;COL18A1;collagen, type XVIII, alpha 1 |
Definition | antiangiogenic agent|collagen alpha-1(XVIII) chain|endostatin|multi-functional protein MFP |
Position | 21q22.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | FOXA1 transcription factor network;PID Curated;200194 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | Protein digestion and absorption;KEGG PATHWAY;hsa04974 |
Disease | REPRODUCTION;GAD |
Disease | Knobloch syndrome, type 1;OMIM |
Disease | endometriosis;GAD |
Disease | breast cancer;GAD |
Disease | Diabetes Mellitus, Type 2;GAD |
Disease | CANCER;GAD |
Disease | METABOLIC;GAD |
Disease | obesity;GAD |
External Links | |
Links to Entrez Gene | 80781 |
Links to all GeneRIF Items | 80781 |
Links to iHOP | 80781 |
Sequence Information | |
Nucleotide Sequence | >80781 : length: 6615 AGCTCCAGCCGCACTGCCCCGATGGCTCCCTACCCCTGTGGCTGCCACATCCTGCTGCTG CTCTTCTGCTGCCTGGCGGCTGCCCGGGCCAACCTGCTGAACCTGAACTGGCTTTGGTTC AATAATGAGGACACCAGCCATGCAGCTACCACGATCCCTGAGCCCCAGGGGCCCCTGCCT GTGCAGCCCACAGCAGATACCACCACACACGTGACCCCCCGGAATGGTTCCACAGAGCCA GCGACAGCCCCTGGCAGCCCTGAGCCACCCTCAGAGCTGCTGGAAGATGGCCAGGACACC CCCACTTCTGCCGAGAGCCCGGACGCGCCAGAGGAGAACATTGCCGGTGTCGGAGCCGAG ATCCTGAACGTGGCCAAAGGCATCCGGAGCTTCGTCCAGCTGTGGAATGACACTGTCCCC ACTGAGAGCTTGGCCAGGGCGGAAACCCTGGTCCTGGAGACTCCTGTGGGCCCCCTTGCC CTCGCTGGGCCTTCCAGCACCCCCCAGGAGAATGGGACCACTCTCTGGCCCAGCCGTGGC ATTCCTAGCTCTCCGGGCGCCCACACAACCGAGGCTGGCACCTTGCCTGCACCCACCCCA TCGCCTCCCTCCCTGGGCAGGCCCTGGGCACCACTCACGGGGCCCTCAGTGCCACCACCA TCTTCAGGTAGAGCTTCTCTCTCCTCCTTGCTGGGCGGGGCCCCTCCCTGGGGAAGCCTG CAGGACCCAGACAGCCAAGGACTCTCGCCCGCCGCAGCCGCTCCCAGCCAGCAGCTCCAA CGCCCTGACGTCCGCCTGCGCACGCCACTTCTGCACCCCCTGGTGATGGGCTCCCTGGGC AAGCACGCGGCCCCCTCCGCCTTCTCCTCTGGGCTCCCGGGCGCACTGTCTCAGGTCGCA GTCACCACTTTAACCAGGGACAGCGGTGCTTGGGTCTCCCACGTGGCTAACTCTGTGGGG CCGGGTCTTGCTAATAACTCTGCCCTGCTCGGGGCTGACCCCGAGGCCCCCGCCGGTCGC TGCCTGCCCCTGCCACCCTCCCTGCCAGTCTGCGGCCACCTGGGCATCTCACGCTTCTGG CTGCCCAACCACCTCCACCACGAGAGCGGCGAGCAGGTGCGGGCCGGGGCACGGGCGTGG GGGGGCCTGCTGCAGACGCACTGCCACCCCTTCCTCGCCTGGTTCTTCTGCCTGCTGCTG GTCCCCCCATGCGGCAGCGTCCCGCCGCCCGCCCCGCCACCCTGCTGCCAGTTCTGCGAG GCCCTGCAGGATGCGTGTTGGAGCCGCCTGGGCGGGGGCCGGCTGCCCGTCGCCTGTGCC TCGCTCCCGACCCAGGAGGATGGGTACTGTGTGCTCATTGGGCCGGCTGCAGAGCGCATC AGCGAGGAGGTGGGGCTGCTGCAGCTCCTTGGGGACCCCCCGCCCCAGCAGGTCACCCAG ACGGATGACCCCGACGTCGGGCTGGCCTACGTCTTTGGGCCAGATGCCAACAGTGGCCAA GTGGCCCGGTACCACTTCCCCAGCCTCTTCTTCCGTGACTTCTCACTGCTGTTCCACATC CGGCCAGCCACAGAGGGCCCAGGGGTGCTGTTCGCCATCACGGACTCGGCGCAGGCCATG GTCTTGCTGGGCGTGAAGCTCTCTGGGGTGCAGGACGGGCACCAGGACATCTCCCTGCTC TACACAGAACCAGGTGCAGGCCAGACCCACACAGCCGCCAGCTTCCGGCTCCCCGCCTTC GTCGGCCAGTGGACACACTTAGCCCTCAGTGTGGCAGGTGGCTTTGTGGCCCTCTACGTG GACTGTGAGGAGTTCCAGAGAATGCCGCTTGCTCGGTCCTCACGGGGCCTGGAGCTGGAG CCTGGCGCCGGGCTCTTCGTGGCTCAGGCGGGGGGAGCGGACCCTGACAAGTTCCAGGGG GTGATCGCTGAGCTGAAGGTGCGCAGGGACCCCCAGGTGAGCCCCATGCACTGCCTGGAC GAGGAAGGCGATGACTCAGATGGGGCATCCGGAGACTCTGGCAGCGGGCTCGGGGACGCC CGGGAGCTTCTCAGGGAGGAGACGGGCGCGGCCCTAAAACCCAGGCTCCCCGCGCCACCC CCCGTCACCACGCCACCCTTGGCTGGAGGCAGCAGCACGGAAGATTCCAGAAGTGAAGAA GTCGAGGAGCAGACCACGGTGGCTTCGTTAGGAGCTCAGACACTTCCTGGCTCAGATTCT GTCTCCACGTGGGACGGGAGTGTCCGGACCCCTGGGGGCCGCGTGAAAGAGGGCGGCCTG AAGGGGCAGAAAGGGGAGCCAGGTGTTCCGGGCCCACCTGGCCGGGCAGGCCCCCCAGGA TCCCCATGCCTACCTGGTCCCCCGGGTCTCCCGTGCCCAGTGAGTCCCCTGGGTCCTGCA GGCCCAGCGTTGCAAACTGTCCCCGGACCACAAGGACCCCCAGGGCCTCCGGGGAGGGAC GGCACCCCTGGAAGGGACGGCGAGCCGGGCGACCCCGGTGAAGACGGAAAGCCGGGCGAC ACCGGGCCACAAGGCTTCCCCGGGACTCCAGGGGACGTAGGTCCCAAGGGCGACAAGGGA GACCCTGGGGTTGGAGAGAGAGGGCCCCCAGGACCCCAAGGGCCTCCAGGGCCCCCAGGA CCCTCCTTCAGACACGACAAGCTGACCTTCATTGACATGGAGGGATCTGGCTTCGGGGGC GATCTGGAGGCCCTGCGGGGTCCTCGAGGCTTCCCTGGACCTCCCGGACCCCCCGGTGTC CCAGGCCTGCCCGGCGAGCCAGGCCGCTTTGGGGTGAACAGCTCCGACGTCCCAGGACCC GCCGGCCTTCCTGGTGTGCCTGGGCGCGAGGGTCCCCCCGGGTTTCCTGGCCTCCCGGGA CCCCCAGGCCCTCCGGGAAGAGAGGGGCCCCCAGGAAGGACTGGGCAGAAAGGCAGCCTG GGTGAAGCAGGCGCCCCAGGACATAAGGGGAGCAAGGGAGCCCCCGGTCCTGCTGGTGCT CGTGGGGAGAGCGGCCTGGCAGGAGCCCCCGGACCTGCTGGACCACCAGGCCCCCCTGGG CCCCCTGGGCCCCCAGGACCAGGACTCCCCGCTGGATTTGATGACATGGAAGGCTCCGGG GGGCCCTTCTGGTCAACAGCCCGAAGCGCTGATGGGCCACAGGGACCTCCCGGCCTGCCG GGACTTAAGGGGGATCCTGGCGTGCCTGGGCTGCCGGGGGCGAAGGGAGAAGTTGGAGCA GATGGAGTCCCCGGGTTCCCCGGCCTCCCTGGCAGAGAGGGCATTGCTGGGCCCCAGGGG CCAAAGGGAGACAGAGGCAGCCGGGGAGAAAAGGGAGATCCAGGGAAGGACGGAGTCGGG CAGCCGGGCCTCCCTGGCCCCCCCGGACCCCCGGGACCTGTGGTCTACGTGTCGGAGCAG GACGGATCCGTCCTGAGCGTGCCGGGACCTGAGGGCCGGCCGGGTTTCGCAGGCTTTCCC GGACCTGCAGGACCCAAGGGCAACCTGGGCTCTAAGGGCGAACGAGGCTCCCCGGGACCC AAGGGTGAGAAGGGTGAACCGGGCAGCATCTTCAGCCCCGACGGCGGTGCCCTGGGCCCT GCCCAGAAAGGAGCCAAGGGAGAGCCGGGCTTCCGAGGACCCCCGGGTCCATACGGACGG CCGGGGTACAAGGGAGAGATTGGCTTTCCTGGACGGCCGGGTCGCCCCGGGATGAACGGA TTGAAAGGAGAGAAAGGGGAGCCGGGAGATGCCAGCCTTGGATTTGGCATGAGGGGAATG CCCGGCCCCCCAGGACCTCCAGGGCCCCCAGGCCCTCCAGGGACTCCTGTTTACGACAGC AATGTGTTTGCTGAGTCCAGCCGCCCCGGGCCTCCAGGATTGCCAGGGAATCAGGGCCCT CCAGGACCCAAGGGCGCCAAAGGAGAAGTGGGCCCCCCCGGACCACCAGGGCAGTTTCCG TTTGACTTTCTTCAGTTGGAGGCTGAAATGAAGGGGGAGAAGGGAGACCGAGGTGATGCA GGACAGAAAGGCGAAAGGGGGGAGCCCGGGGGCGGCGGTTTCTTCGGCTCCAGCCTGCCC GGCCCCCCCGGCCCCCCAGGCCCACGTGGCTACCCTGGGATTCCAGGTCCCAAGGGAGAG AGCATCCGGGGCCAGCCCGGCCCACCTGGACCTCAGGGACCCCCCGGCATCGGCTACGAG GGGCGCCAGGGCCCTCCCGGCCCCCCAGGCCCCCCAGGGCCCCCTTCATTTCCTGGCCCT CACAGGCAGACTATCAGCGTTCCCGGCCCTCCGGGCCCCCCTGGGCCCCCTGGGCCCCCT GGAACCATGGGCGCCTCCTCAGGGGTGAGGCTCTGGGCTACACGCCAGGCCATGCTGGGC CAGGTGCACGAGGTTCCCGAGGGCTGGCTCATCTTCGTGGCCGAGCAGGAGGAGCTCTAC GTCCGCGTGCAGAACGGGTTCCGGAAGGTCCAGCTGGAGGCCCGGACACCACTCCCACGA GGGACGGACAATGAAGTGGCCGCCTTGCAGCCCCCCGTGGTGCAGCTGCACGACAGCAAC CCCTACCCGCGGCGGGAGCACCCCCACCCCACCGCGCGGCCCTGGCGGGCAGATGACATC CTGGCCAGCCCCCCTCGCCTGCCCGAGCCCCAGCCCTACCCCGGAGCCCCGCACCACAGC TCCTACGTGCACCTGCGGCCGGCGCGACCCACAAGCCCACCCGCCCACAGCCACCGCGAC TTCCAGCCGGTGCTCCACCTGGTTGCGCTCAACAGCCCCCTGTCAGGCGGCATGCGGGGC ATCCGCGGGGCCGACTTCCAGTGCTTCCAGCAGGCGCGGGCCGTGGGGCTGGCGGGCACC TTCCGCGCCTTCCTGTCCTCGCGCCTGCAGGACCTGTACAGCATCGTGCGCCGTGCCGAC CGCGCAGCCGTGCCCATCGTCAACCTCAAGGACGAGCTGCTGTTTCCCAGCTGGGAGGCT CTGTTCTCAGGCTCTGAGGGTCCGCTGAAGCCCGGGGCACGCATCTTCTCCTTTGACGGC AAGGACGTCCTGAGGCACCCCACCTGGCCCCAGAAGAGCGTGTGGCATGGCTCGGACCCC AACGGGCGCAGGCTGACCGAGAGCTACTGTGAGACGTGGCGGACGGAGGCTCCCTCGGCC ACGGGCCAGGCCTCCTCGCTGCTGGGGGGCAGGCTCCTGGGGCAGAGTGCCGCGAGCTGC CATCACGCCTACATCGTGCTCTGCATTGAGAACAGCTTCATGACTGCCTCCAAGTAGCCA CCGCCTGGATGCGGATGGCCGGAGAGGACCGGCGGCTCGGAGGAAGCCCCCACCGTGGGC AGGGAGCGGCCGGCCAGCCCCTGGCCCCAGGACCTGGCTGCCATACTTTCCTGTATAGTT CACGTTTCATGTAATCCTCAAGAAATAAAAGGAAGCCAAAGAGTGTATTTTTTTAAAAGT TTAAAACAGAAGCCTGATGCTGACATTCACCTGCCCCAACTCTCCCCTGACCTGTGAGCC CAGCTGGGTCAGGCAGGGTGCAGTATCATGCCCTGTGCAACCTCTTGGCCTGATCAGACC ACGGCTCGATTTCTCCAGGATTTCCTGCTTTGGGAAGCCGTGCTCGCCCCAGCAGGTGCT GACTTCATCTCCCACCTAGCAGCACCGTTCTGTGCACAAAACCCAGACCTGTTAGCAGAC AGGCCCCGTGAGGCAATGGGAGCTGAGGCCACACTCAGCACAAGGCCATCTGGGCTCCTC CAGGGTGTGTGCTCGCCCTGCGGTAGATGGGAGGGAGGCTCAGGTCCCTGGGGCTAGGGG GAGCCCCTTCTGCTCAGCTCTGGGCCATTCTCCACAGCAACCCCAGGCTGAAGCAGGTTC CCAAGCTCAGAGGCGCACTGTGACCCCCAGCTCCGGCCTGTCCTCCAACACCAAGCACAG CAGCCTGGGGCTGGCCTCCCAAATGAGCCATGAGATGATACATCCAAAGCAGACAGCTCC ACCCTGGCCGAGTCCAAGCTGGGAGATTCAAGGGACCCATGAGTTGGGGTCTGGCAGCCT CCCATCCAGGGCCCCCATCTCATGCCCCTGGCTGGGACGTGGCTCAGCCAGCACTTGTCC AGCTGAGCGCCAGGATGGAACACGGCCACATCAAAGAGGCTGAGGCTGGCACAGGACATG CGGTAGCCAGCACACAGGGCAGTGAGGGAGGGCTGTCATCTGTGCACTGCCCATGGACAG GCTGGCTCCAGATGCAGGGCAGTCATTGGCTGTCTCCTAGGAAACCCATATCCTTACCCT CCTTGGGACTGAAGGGGAACCCCGGGGTGCCCACAGGCCGCCCTGCGGGTGAACAAAGCA GCCACGAGGTGCAACAAGGTCCTCTGTCAGTCACAGCCACCCCTGAGATCCGGCAACATC AACCCGAGTCATTCGTTCTGTGGAGGGACAAGTGGACTCAGGGCAGCGCCAGGCTGACCA CAGCACAGCCAACACGCACCTGCCTCAGGACTGCGACGAAACCGGTGGGGCTGGTTCTGT AATTGTGTGTGATGTGAAGCCAATTCAGACAGGCAAATAAAAGTGACCTTTTACACTGAA AAAAAAAAAAAAAAA |
Protein Sequence | >80781 : length: 1751 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSGRASLSSLLGGAPPWGSLQDPDSQG LSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSSGLPGALSQVAVTTLTRD SGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPVCGHLGISRFWLPNHLHH ESGEQVRAGARAWGGLLQTHCHPFLAWFFCLLLVPPCGSVPPPAPPPCCQFCEALQDACW SRLGGGRLPVACASLPTQEDGYCVLIGPAAERISEEVGLLQLLGDPPPQQVTQTDDPDVG LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQR MPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSD GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP GTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP GLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSV PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKG EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP GPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLE AEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPG PPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASS GVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVA ALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRP ARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSS RLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHP TWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVL CIENSFMTASK |