| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 80243 |
Name | PREX2 |
Synonym | 6230420N16Rik|DEP.2|DEPDC2|P-REX2|PPP1R129;phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2;PREX2;phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
Definition | DEP domain-containing protein 2|PtdIns(3,4,5)-dependent Rac exchanger 2|phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein|protein phosphatase 1, regulatory subunit 129 |
Position | 8q13.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Regulation of RAC1 activity;PID Curated;200165 |
External Links | |
Links to Entrez Gene | 80243 |
Links to all GeneRIF Items | 80243 |
Links to iHOP | 80243 |
Sequence Information | |
Nucleotide Sequence | >80243 : length: 5132 GCGCCGCGCTGCGCACCGCCGCCGACCATGAGCGAGGACAGCCGCGGAGACAGCCGCGCC GAGAGCGCCAAGGACCTGGAGAAGCAGCTTCGCCTGCGCGTGTGCGTGCTCAGCGAGCTC CAGAAGACCGAGCGGGACTATGTGGGCACGCTGGAGTTCCTGGTGTCGGCATTCTTACAC AGAATGAACCAGTGTGCAGCATCAAAAGTTGACAAAAATGTGACAGAAGAAACAGTGAAG ATGTTGTTCTCAAACATTGAAGACATCCTTGCAGTACATAAAGAATTCTTAAAAGTCGTG GAAGAATGCTTACACCCCGAACCTAATGCTCAACAAGAAGTGGGAACCTGCTTTCTTCAC TTTAAAGACAAGTTTCGTATCTATGATGAATATTGTAGTAACCATGAGAAGGCACAAAAA TTACTTCTTGAACTCAACAAAATAAGAACAATCCGGACATTTCTTTTGAACTGCATGCTG CTTGGAGGACGGAAGAACACAGATGTTCCCTTGGAAGGATATTTAGTAACACCAATACAA AGAATATGCAAGTACCCTCTTATTTTGAAGGAGTTGCTGAAGCGGACTCCACGGAAACAC AGTGACTATGCAGCAGTGATGGAAGCCCTCCAAGCCATGAAAGCTGTCTGTTCCAACATA AACGAGGCCAAGAGACAGATGGAGAAGTTAGAAGTTTTAGAGGAATGGCAGTCTCACATT GAAGGCTGGGAGGGGTCCAACATCACTGACACCTGCACTGAAATGCTAATGTGTGGAGTC TTACTGAAAATTTCTTCTGGAAATATTCAAGAACGGGTGTTTTTTCTTTTCGATAATCTT TTGGTGTACTGCAAAAGAAAACACAGACGGTTGAAGAACAGCAAGGCATCTACAGATGGA CATCGGTACCTTTTTCGTGGCCGGATCAACACGGAGGTGATGGAAGTGGAGAATGTGGAT GATGGCACCGCTGATTTCCATAGCAGTGGACACATTGTTGTTAATGGATGGAAGATACAT AACACAGCAAAAAATAAATGGTTTGTTTGTATGGCAAAAACACCTGAAGAGAAGCATGAA TGGTTTGAAGCTATTTTGAAAGAAAGAGAACGGCGGAAAGGTTTAAAATTAGGAATGGAG CAAGATACCTGGGTCATGATCTCTGAACAGGGTGAGAAACTTTATAAAATGATGTGCAGA CAAGGAAATCTGATCAAAGACCGAAAGAGAAAACTGACTACGTTCCCTAAATGCTTTCTT GGAAGCGAATTTGTGTCATGGCTGTTGGAAATTGGAGAGATTCACAGGCCTGAGGAAGGC GTGCACTTGGGACAAGCATTATTAGAAAATGGAATCATTCACCATGTTACTGATAAACAT CAATTCAAACCAGAACAGATGTTATATAGATTTCGCTATGATGATGGAACATTTTATCCA AGAAATGAGATGCAGGACGTGATTTCAAAGGGTGTAAGATTATATTGTCGTCTTCATAGC CTTTTTACTCCAGTGATAAGAGATAAAGATTACCATTTAAGGACCTACAAATCTGTGGTC ATGGCCAACAAACTGATAGACTGGTTAATTGCACAGGGAGATTGCCGCACCAGAGAAGAG GCAATGATATTTGGCGTTGGACTCTGTGACAATGGATTTATGCACCATGTCCTTGAAAAA AGCGAATTCAAAGATGAACCCCTACTTTTCCGTTTTTTTTCGGATGAGGAAATGGAGGGA TCAAATATGAAACATCGACTTATGAAACATGACTTAAAAGTTGTGGAAAATGTTATAGCT AAGTCATTATTGATTAAATCCAATGAAGGCAGCTATGGCTTTGGATTAGAAGACAAAAAT AAAGTTCCAATAATAAAGTTGGTAGAAAAGGGATCTAATGCTGAGATGGCTGGCATGGAA GTCGGGAAAAAGATTTTTGCTATTAATGGTGACCTAGTTTTTATGAGACCTTTCAATGAA GTGGATTGCTTCCTGAAATCGTGTTTAAACAGCAGAAAACCTCTAAGAGTTCTTGTGAGC ACAAAGCCAAGAGAGACAGTGAAAATTCCAGATTCAGCTGATGGACTTGGCTTCCAGATC CGGGGATTTGGCCCTTCTGTTGTGCATGCTGTAGGAAGAGGAACTGTGGCTGCAGCAGCT GGTCTTCACCCTGGACAGTGCATTATCAAGGTGAATGGAATCAATGTCAGCAAAGAGACA CATGCCAGTGTCATTGCACACGTTACAGCCTGCAGGAAGTACAGGCGGCCAACGAAGCAA GATTCCATACAATGGGTTTATAATAGCATTGAGAGTGCTCAAGAAGACCTTCAAAAATCT CACTCCAAGCCCCCTGGAGATGAAGCAGGGGATGCTTTTGACTGTAAAGTAGAAGAGGTT ATTGACAAATTCAACACTATGGCCATCATTGATGGGAAGAAGGAGCATGTGAGTCTGACA GTGGACAATGTCCACCTGGAATATGGTGTCGTGTATGAGTACGACAGCACAGCTGGCATC AAGTGCAATGTGGTGGAAAAGATGATTGAGCCCAAAGGTTTCTTCAGCTTAACTGCCAAG ATTCTTGAAGCCCTGGCTAAAAGTGATGAGCATTTTGTACAAAACTGTACCAGCCTAAAT TCTCTAAATGAAGTGATTCCTACTGACCTTCAGAGTAAATTCAGTGCCCTTTGCAGTGAA AGAATTGAACACCTATGTCAGAGAATATCCAGTTATAAAAAGTTTTCTCGTGTACTGAAG AATAGGGCCTGGCCTACTTTTAAACAGGCCAAATCTAAAATCTCCCCACTGCACAGCAGT GATTTCTGCCCTACCAACTGCCATGTCAATGTGATGGAAGTTTCTTATCCCAAAACATCA ACCTCTTTGGGAAGTGCATTTGGTGTTCAGTTGGATAGCAGGAAGCATAATTCTCATGAT AAAGAAAACAAATCTTCGGAGCAAGGGAAACTGAGCCCTATGGTGTACATTCAGCACACC ATCACAACCATGGCGGCCCCTTCAGGTCTGTCTCTGGGACAGCAGGATGGCCATGGTCTC AGGTATCTGCTAAAAGAAGAAGACTTAGAAACCCAAGACATCTATCAGAAACTGCTGGGC AAACTTCAGACTGCACTGAAAGAGGTGGAGATGTGTGTTTGTCAAATAGATGACCTTCTG TCTTCAATAACATATTCTCCTAAATTAGAACGTAAGACATCAGAGGGCATAATACCAACA GACAGTGACAATGAGAAGGGAGAAAGAAACAGCAAACGGGTATGTTTTAATGTAGCAGGA GATGAACAGGAAGATTCTGGTCATGACACCATCAGCAACAGAGACTCTTACAGTGACTGC AACAGCAATAGGAATTCCATCGCCTCCTTCACCAGCATCTGCAGCAGCCAGTGCAGCTCG TATTTCCACAGTGATGAAATGGACTCAGGTGATGAACTTCCCTTAAGTGTTCGCATATCT CATGATAAACAGGACAAGATACATAGTTGCCTTGAGCATCTTTTCAGCCAGGTGGATTCA ATTACCAATCTCCTAAAAGGGCAGGCTGTTGTGAGGGCCTTTGACCAAACCAAGTATCTC ACTCCAGGCCGAGGATTGCAAGAATTTCAACAGGAAATGGAACCAAAGCTGAGTTGTCCA AAAAGGCTACGGCTTCATATCAAGCAAGATCCTTGGAATCTTCCCAGCAGCGTCCGGACT CTTGCTCAGAACATCAGGAAATTTGTTGAAGAGGTAAAGTGTAGGCTACTCCTGGCTCTT CTTGAATATTCAGATAGTGAGACACAGCTCCGTAGAGACATGGTTTTCTGCCAGACTCTT GTGGCCACTGTCTGTGCCTTCTCTGAGCAGCTCATGGCGGCCTTGAACCAGATGTTTGAC AACAGCAAGGAAAATGAGATGGAAACTTGGGAAGCCAGCAGGAGGTGGCTGGACCAGATA GCGAATGCAGGTGTTCTTTTTCACTTTCAGTCACTTCTGTCACCAAACTTGACAGATGAA CAAGCCATGTTAGAAGATACACTGGTTGCACTATTTGATTTGGAAAAGGTTTCCTTTTAC TTTAAACCATCAGAAGAGGAACCTCTGGTTGCAAATGTTCCTCTTACATATCAAGCAGAA GGAAGTCGGCAAGCTCTGAAAGTTTACTTCTACATTGATAGTTATCATTTTGAACAACTT CCTCAACGGCTGAAAAATGGAGGAGGGTTTAAAATTCATCCTGTTCTTTTTGCACAAGCA CTAGAGAGCATGGAAGGATATTATTACAGAGACAATGTTTCTGTGGAAGAATTTCAAGCT CAGATAAATGCAGCCTCACTGGAAAAGGTCAAACAGTACAACCAGAAGCTCAGGGCATTC TACTTGGACAAGTCAAATTCACCACCAAACTCCACATCCAAAGCTGCCTATGTAGATAAG CTAATGAGGCCTCTCAACGCTTTGGATGAACTTTACCGACTGGTAGCCTCGTTTATCAGA TCCAAGCGCACAGCTGCCTGTGCAAACACAGCTTGCAGTGCTTCTGGGGTTGGACTGCTG TCAGTTTCCTCGGAGCTGTGCAACAGGCTGGGCGCCTGCCACATCATCATGTGCAGCAGC GGTGTGCATCGGTGCACCCTGAGCGTGACGCTGGAGCAAGCCATCATTCTGGCCAGAAGC CACGGACTGCCACCTCGTTACATCATGCAGGCTACAGATGTGATGCGGAAGCAGGGAGCA AGAGTTCAGAACACAGCGAAGAATTTGGGAGTCAGAGACCGGACTCCACAGTCTGCACCA AGGCTGTACAAGCTGTGCGAGCCACCTCCCCCAGCTGGAGAAGAATGAAAAGAACTCCCA AGAAACCAGGCAGGCAGAAGCTCCTGAATGCTGGACTAGACAAACTACATGCTGGCTAAA CATTCTCCACTGAAGATACATCAATGCTTTTTTTTTTTTTTTTTTCTGTAAATCTTTCTT CCCATTGCAAACAAGTAGTGATCAGTTTATACTTTGATATTTATGCTGGAAATGGATAGA AGTTCAATCAGACAGTTCAGCTTCACGAACTGATGTCTCTCTGTATTGACATTAAGTATT CACTTTTAGAGTAAAATCCATCCCTGGGACAT |
Protein Sequence | >80243 : length: 1606 MSEDSRGDSRAESAKDLEKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASK VDKNVTEETVKMLFSNIEDILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYD EYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLIL KELLKRTPRKHSDYAAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQSHIEGWEGSNIT DTCTEMLMCGVLLKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYLFRGRI NTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKTPEEKHEWFEAILKER ERRKGLKLGMEQDTWVMISEQGEKLYKMMCRQGNLIKDRKRKLTTFPKCFLGSEFVSWLL EIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRNEMQDVIS KGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLC DNGFMHHVLEKSEFKDEPLLFRFFSDEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNE GSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFMRPFNEVDCFLKSCL NSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCII KVNGINVSKETHASVIAHVTACRKYRRPTKQDSIQWVYNSIESAQEDLQKSHSKPPGDEA GDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGIKCNVVEKMI EPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQSKFSALCSERIEHLCQRI SSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGV QLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTMAAPSGLSLGQQDGHGLRYLLKEEDL ETQDIYQKLLGKLQTALKEVEMCVCQIDDLLSSITYSPKLERKTSEGIIPTDSDNEKGER NSKRVCFNVAGDEQEDSGHDTISNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDS GDELPLSVRISHDKQDKIHSCLEHLFSQVDSITNLLKGQAVVRAFDQTKYLTPGRGLQEF QQEMEPKLSCPKRLRLHIKQDPWNLPSSVRTLAQNIRKFVEEVKCRLLLALLEYSDSETQ LRRDMVFCQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHF QSLLSPNLTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLTYQAEGSRQALKVY FYIDSYHFEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYRDNVSVEEFQAQINAASLEK VKQYNQKLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLVASFIRSKRTAACAN TACSASGVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAIILARSHGLPPRYIM QATDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPAGEE |