| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7372 |
Name | UMPS |
Synonym | OPRT;uridine monophosphate synthetase;UMPS;uridine monophosphate synthetase |
Definition | OMPdecase|OPRTase|UMP synthase|orotate phosphoribosyltransferase|orotidine 5'-phosphate decarboxylase|uridine 5'-monophosphate synthase |
Position | 3q13 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Pyrimidine biosynthesis;PID Reactome;500230 |
Pathway | pyrimidine ribonucleotides de novo biosynthesis;BioCyc;PWY0-162 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Pyrimidine metabolism;KEGG PATHWAY;hsa00240 |
Pathway | uridine-5'-phosphate biosynthesis;BioCyc;PWY-5686 |
Pathway | Drug metabolism - other enzymes;KEGG PATHWAY;hsa00983 |
Pathway | Metabolism of nucleotides;Reactome;REACT:1698 |
Disease | Inherited disorders of nucleotide metabolism;KEGG DISEASE |
Disease | Orotic aciduria;KEGG DISEASE;H00198 |
Disease | Oroticaciduria;OMIM |
Disease | Genetic disorders;KEGG DISEASE |
External Links | |
Links to Entrez Gene | 7372 |
Links to all GeneRIF Items | 7372 |
Links to iHOP | 7372 |
Sequence Information | |
Nucleotide Sequence | >7372 : length: 6837 CTGCAGACGAGGCAGGCGGAAGAGGCGGGACTTCGCGGGTGACGTCATCGGGGCGCCGGA GGCCCGGGGCGCCTGGGAATTTGAAGCAAACAGGCAGCGCGCGACAATGGCGGTCGCTCG TGCAGCTTTGGGGCCATTGGTGACGGGTCTGTACGACGTGCAGGCTTTCAAGTTTGGGGA CTTCGTGCTGAAGAGCGGGCTTTCCTCCCCCATCTACATCGATCTGCGGGGCATCGTGTC TCGACCGCGTCTTCTGAGTCAGATGGGATCTCTCTTACGTCACCCAGGCTGGAGTGCAGC TCTGTGATCATAGCTCACTGCAGCCTGGAACTCCTGGGCTTAAGAGATCTTCTTGCCTCG GGTTGCAGATATTTTATTCCAAACTGCCCAAAATGCAGGCATCAGTTTTGACACCGTGTG TGGAGTGCCTTATACAGCTTTGCCATTGGCTACAGTTATCTGTTCAACCAATCAAATTCC AATGCTTATTAGAAGGAAAGAAACAAAGGATTATGGAACTAAGCGTCTTGTAGAAGGAAC TATTAATCCAGGAGAAACCTGTTTAATCATTGAAGATGTTGTCACCAGTGGATCTAGTGT TTTGGAAACTGTTGAGGTTCTTCAGAAGGAGGGCTTGAAGGTCACTGATGCCATAGTGCT GTTGGACAGAGAGCAGGGAGGCAAGGACAAGTTGCAGGCGCACGGGATCCGCCTCCACTC AGTGTGTACATTGTCCAAAATGCTGGAGATTCTCGAGCAGCAGAAAAAAGTTGATGCTGA GACAGTTGGGAGAGTGAAGAGGTTTATTCAGGAGAATGTCTTTGTGGCAGCGAATCATAA TGGTTCTCCCCTTTCTATAAAGGAAGCACCCAAAGAACTCAGCTTCGGTGCACGTGCAGA GCTGCCCAGGATCCACCCAGTTGCATCGAAGCTTCTCAGGCTTATGCAAAAGAAGGAGAC CAATCTGTGTCTATCTGCTGATGTTTCACTGGCCAGAGAGCTGTTGCAGCTAGCAGATGC TTTAGGACCTAGTATCTGCATGCTGAAGACTCATGTAGATATTTTGAATGATTTTACTCT GGATGTGATGAAGGAGTTGATAACTCTGGCAAAATGCCATGAGTTCTTGATATTTGAAGA CCGGAAGTTTGCAGATATAGGAAACACAGTGAAAAAGCAGTATGAAGGAGGTATCTTTAA AATAGCTTCCTGGGCAGATCTAGTAAATGCTCACGTGGTGCCAGGCTCAGGAGTTGTGAA AGGCCTGCAAGAAGTGGGCCTGCCTTTGCATCGGGGGTGCCTCCTTATTGCGGAAATGAG CTCCACCGGCTCCCTGGCCACTGGGGACTACACTAGAGCAGCGGTTAGAATGGCTGAGGA GCACTCTGAATTTGTTGTTGGTTTTATTTCTGGCTCCCGAGTAAGCATGAAACCAGAATT TCTTCACTTGACTCCAGGAGTTCAGTTGGAAGCAGGAGGAGATAATCTTGGCCAACAGTA CAATAGCCCACAAGAAGTTATTGGCAAACGAGGTTCCGATATCATCATTGTAGGTCGTGG CATAATCTCAGCAGCTGATCGTCTGGAAGCAGCAGAGATGTACAGAAAAGCTGCTTGGGA AGCGTATTTGAGTAGACTTGGTGTTTGAGTGCTTCAGATACATTTTTCAGATACAATGTG AAGACATTGAAGATATGTGGTCCTCCTGAAAGTCACTGGCTGGAAATAATCCAATTATTC CTGCTTGGATTCTTCCACAGGGCCTGTGTAAGAATGGGTTCTGGAGTTCTCATGGTCTTT AGGAAATATTGAGTAATTTGTAATCACCGCATTGATACTATAATAAGTTCATTCTTAAGC TTGCTTTTTTTGAGACTGGTGTTTGTTAGACAGCCACAGTCCTGTCTGGGTTAGGGTCTT CCACATTTGAGGATCCTTCCTATCTCTCCATGGGACTAGACTGCTTTGTTATTCTATTTA TTTTTTAATTTTTTTCGAGACAGGATCTCACTCTGTTGCCCAGGATGGAGTGCAGTGGTG AGATCACGGCTCATTGCAGCCTCGACCTCCCAGGTGATCCTCCCACCTCAGCTTCCAGAT TAGCTGGTGCTATAGGCATGCACCACCACGTCCATCTAAATTTCTTTATTATTTGTAGAG ATGAGGTCTTGCCATGTTACCCAGGCTGGTCTCAACTCCTGGGCTCAAGCGATCCTCCTG CCTCAGTCTCTCAAAGTGCTGGGATTACAGGTGTGAGCCACTGTGCCCAGCCTAATTGCA GTAAGACAAAAATTCTAGGGCACCAAGAGGCTAAAGTCAGCACAGCTTTTCTTGTGTCCT GTATTCTCTGTCTAATGTGTTGCCCAAATAATACCTAATTGTTAGCCATTCCCCTCCATC TCTGGCCTAAAAGTGATAGTCCAGGTATCCACATGGGCTGGTTCCCAGAACTGCCATTGC TCACTCTCCAAAGAGGGGAAGGTGGGGAAGGGGAAGGTGACTATAGCTCAGCTCCTGAGC TAGTATCTGGCTGTTATTTCAACAACCGGAGTTGGGGTTTGGGCTCATTTTTTCCCCTAG CCAGCAATTATGGACCAGTAGTAACACAAGTGACAGCTTCCTGTGACTGACTTCACAATT AGGAGGTCTAAGATTCCATTTGGGTATTTGCTTAAGGATCCCACATAATTGTCCCAACGG TCATTAGTAGAGGGGAGGTAAGCCTTCATTAATAATAAAGAGAAAGCCCACATTCAAGGT GGTGTTTGAGCAGGGGCAGGGTGAGGGCTGTCCCGGTGCTCATTGCACCAGCACACTCAC ATTCCTTCTCATTTGGGGCCCACCTGCAGGAAGTGGCACAGGATCAGCCATTTCCCCACC CTTGTCAGCTGATGGCCCACTGTTCTTTAATGACTCAGAGGAATGCCTAGGATTTTTTTT TTTTTTTGAGACAGAATCTCACTGTCGCCCAGGCTGGAGTTCAGTGGCACGATCTCGGCT CACTGCAACTTCTGCCTCTCTGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCCGAGTAGCT GGGACTACAAGCCTAGGATTTTTAACTCAGGTTTTTATTATATTCCCTCCTGAAGTTTTT ACTTCAAGAGCTTCTGCTCTAAAGTCCAATTTGGGCTTCATGTCCCCAGTGCTGCATCTC CAGGGAAATGCTGTCTGTGGGAGAGACCAACTCTCAAGGAAGAAGTGGCCACAGAAGGAG CAGGAAGGGAGTTGGCCCTCAGGGCTACTCTGGGGAAGCCAAAAGTCATGAAGGGGAGAA GAATTTTCTGACAAAAACTTGCAGGAATCTCTTAGGTGTCTTCAGTGTTGGAGTGATATG TTGAGAGGCCTTTGGAGTGATGTGCTGAGGTCTCAGGCGCCCACCTCCCTGGCTGTCACT TCCATGTGTCAGTGGTTCTCCCACTTTAGCAGGTATCAGAGTCACCTGGAGTCTTGTCAA AACAGGTACCAGCCCCACCCGCAGCGTTTCTGACTCTGGGTAGCTCTGGGATGGGGCTTG AGAATTTGCGTTTCCAAAAAGGTCCCAGGTGATGCTGCGGTTGCCTGCGCAGGGACTGGA CTTTGAGAACCACTTCACTGGTTATTCACATTTCTGCCTCTGCAGTGAGACAGCCTTGAG GTCTGCCTCCTGCTAAGAGTCACATGCTCCTGTCCTTTAGAAATGTGGGCTCCTGCCATC TCCAGGACGCAGGCACTGTTCCTGTTGATGAACCCTATTTCACAGGACCCCTGCTAAGGT GATTTGAGGGGAAATGAGAGGAGGCTCAAATAATCACCCAGCCCCTGCCACTTACTGAAA GTGTAGGTCCTTGTGCCCCACACCATCAGAGTTTCTGCGTTAGCAGATTTGTGGTTTGCC CAGCAGCCTGGGCGTGTGCATTTCTAATGGGTGCCTCAAGTGATCTGTTTCTGATTTGTA TTTCTATTGTGAAGAGTCAGCCCAGTACTGCAGGCCTCTTACCTAAGCAGAATCCCAGTC TGGCATCAAAGCTTTAGAGGACAAGTTGATTCAGGCAGAGAAGAACTTGGGCTATACAAG CGCTGTTCTTCAGCATTGAAGTATTTTGGAGGCATTAGATAGTTTAACCCTTTCTCAGTC AAGGAATATTTACAGAACATGATCTCTGGGCATTGTAACTCCTGGTCTTAGTGGGGAATA TAGGGACCCCATGTCTCCATGGGGTGCACAGAATGTCTGTGAGACTGATGGAGTGGAGAA CGCCATCCCCCAGCCTCTCCAGCTACTCGAGGCATTCTGTAGAACATAAGCCCATAGATT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCATGCGCGCGCGTGCGCAC TGGAGGAACCTAAGAAACTATTTGGTGCACTTCCTCTTATTTTAGAGCTCCCAAAGTGTA GCTCCAGAATCGTAAAGGGATATGCTCAGTCTCACAGCCAGCCTGTGGATCTCAGTCCCA ACACTCACCCTTGTGCTACTGAGTCAGCTCTAAGAAAATCTGCCAAAAGTAGGCCGAGGG CTGGTTTTTTGTTTTGTTTTGTTTGTTTGATACAGGGTCTTCACTCTGTTGCCCAGGCTG GAGTATATCATGGCTCACTGCAACCTTGACTTGGGCTCAAGCGATCCGCTCAAGTAGCTG GAACTACTCTCAAGTAGCTCTCAAGAGCCTCTCGAGTGGCTGGAACTACAGGCGTGCACC ACCACAGCTGGTTAATTTTTAAAATTTTTTGTAGAGACGGTGGAGGAGGTTCTCACTGTG ACTCAGTGTGTGCCCGACAGCAGAGCCCACACCACTCCAGTTGCAGTGGTTGCCATCTGG GTCATCAGACCTGGCTGTCAGGGGTGCAGCCACAGGAGAGCCAACAGCAGAGGGTGCTGG CCGCTGAGCTAGCTGCTAATGCTGGCCTGGGTGCAGTTCTCATCCAAAGTACCCGGTGGG TGGGAGTCACTCAGTACCAGTTCCGAGCCTGAACCCAAACTCTCGTGTTTCTGCTCACCC CTCTCTGGCTTCTGCCACCACATGGGAAGAATATGCCCTGGTTAGCCCATGGCTTCTGAA GAGCAAGAGAAAGTAGAGCAGAGCCTACTCCAGCCTCCCCCGTCCAATGTATGAAAGCCC CAGCTGATCTGTAAGCCTGGGAGCGTGATAAATGCTTAGTAGTGCATGCCATGGAGTTCC AGGGTGGTTTATTACACGGCAATATCTAGCTAAATACATTTAACTTGCTGCAGCTCTCTG GATCCAGCCTGGTTACCAGGAAGACAAAAACTGGGCTCCACCAGGAACCAGTCTTCTGCC TTCCCAACCATCACCTCTGGCTGCATCAGCGATCTCTCCCAGCGAAATAGCTGCTTGGTC TTGTGTGAATCCTGTACTTTAACACAGTGGACCAAGTGTCAGTCATTGAAAATGACCATG AGTAACCCTGTGGACTCTCTGCAGCTTGGTTCCTTTGCCCCTTAACAGGTGGGTATGAAT CGTGTCTTCAGTGCCAGGGCTGAATGAGAAAGGGCATTCCTTTTTGAAGGAATCTGATAC TAAACACAAAGCATGAGAAAAATCAGGACTTGTTGGAGTTATATTTTTAAAATATATATT TTAACAGTTATATATATTAGATATAATATATAATAGTATATATAAATAATACTATATTGC CCAGGCTGGTCTCGAACTCCTTAGCTCAAGTGATCCTCCTGCCTTGGCTTCCCAAAGTGC TAGGATTACAGGTGTGAGCCACTGCTCCCGGCCTGTTGGAGTTCTTTACATTTATTTTAT AATCAATGCTGTTTTATTAAATGCGGATTTTATTTTGGATTACAGGATGTAGAATGCCAT ATTTTTCTTAGATCATAGGGCCTTTCACATTTGTAATTTGGCCTTGTATGAGTTACCCTG CAATCCCTTTGTTTTCCCCATAACCCTTCCAAAGGAAGGCCGCAATAGAAATACAAAGAG AAACAAAATAATTAGAATATTTTTTAACTTCTAAAGTTCAAGGTTTTGGCATAAGTCTGG TTTAGAAGCACATTTGCCTAGCCCTTTCCTTCCCACCAAGGGGGAAAGTCTTCCTCTAGA CAAGAGGCAGAGGGCTCCTCAGAGTCAGATCCTGGTGTGGGCTCTCACGTGCTGCTGCTG AATCCCAGGGAAGGAGGGAGGAAGGGCAGTTGACACCCAAAATAAGGGTGGGGAACTGTC AGCAGAGGAGGTCTGTGTCATGTTTTTCAGCGCTGGGGTTGGGGGGAGCCCAGGAGAGCA GGAAGATCCAGAGATCCCTCGCCCCAGCTCGGCCATGTGTGTCTGGGACAGAGCCTGAGG TGGCCTGAGCTTCCTGTGGCTCCAGAGTAACATTATAGAGAAGCTGAATTCTCCTGTTTT TCTGAAAAGGGCATGGGAGTTAGCTGAGAAGCAGACCTGGTGGGCCTGAGAGTCTCAATC GTCAGGTAAGGACAGTCAGTGGGAAGTGGACGGGCCGCACAACCAAGGTTCTCATGAGGA CAACCATGTCTTCGGGGGTGCCCTTGTGCACAGACAGCTCCATAGTCCTGCCTCCAATGT CCCAACACTGCATTGTCTCCCTGCACTTAGCAGCCCTGCAGGGTGAGACTTGGGGAGGAT CCTGAAATGATTGTATTTAACAAGACATGCTGTCCTTGTTTACCTGGAACCTAGCAATGT TGTTTTCTGCCACAACTTGAATAGATACTTGAAGCAGAGATGATGTTGAGTTAAAAAAAA TATATACATAAAAATATGGGTTCTTTTCAACCTGAATAGATGGCCTAAAAATTCAAA |
Protein Sequence | >7372 : length: 480 MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQT AQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCL IIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKML EILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVA SKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELIT LAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLP LHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQ LEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV |