| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7173 |
Name | TPO |
Synonym | MSA|TDH2A|TPX;thyroid peroxidase;TPO;thyroid peroxidase |
Definition | thyroid microsomal antigen|thyroperoxidase |
Position | 2p25 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Tyrosine metabolism;KEGG PATHWAY;hsa00350 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Metabolism of amino acids and derivatives;Reactome;REACT:13 |
Pathway | Hematopoietic cell lineage;KEGG PATHWAY;hsa04640 |
Pathway | thyroid hormone biosynthesis;BioCyc;PWY-6241 |
Pathway | Autoimmune thyroid disease;KEGG PATHWAY;hsa05320 |
Pathway | Hormone biosynthesis;Reactome;REACT:15314 |
Disease | Embryoma;FunDO |
Disease | hypothyroidism;GAD |
Disease | Thrombocytosis;FunDO |
Disease | Thyroid dyshormonogenesis 2A;OMIM |
Disease | Infection;FunDO |
Disease | Hypothyroidism;FunDO |
Disease | Leukemia;FunDO |
Disease | Thyroid gland disease;FunDO |
Disease | METABOLIC;GAD |
Disease | Kidney disease;FunDO |
Disease | Neoplasm metastasis;FunDO |
External Links | |
Links to Entrez Gene | 7173 |
Links to all GeneRIF Items | 7173 |
Links to iHOP | 7173 |
Sequence Information | |
Nucleotide Sequence | >7173 : length: 3889 AATGAGAGCGCTCGCTGTGCTGTCTGTCACGCTGGTTATGGCCTGCACAGAAGCCTTCTT CCCCTTCATCTCGAGAGGGAAAGAACTCCTTTGGGGAAAGCCTGAGGAGTCTCGTGTCTC TAGCGTCTTGGAGGAAAGCAAGCGCCTGGTGGACACCGCCATGTACGCCACGATGCAGAG AAACCTCAAGAAAAGAGGAATCCTTTCTCCAGCTCAGCTTCTGTCTTTTTCCAAACTTCC TGAGCCAACAAGCGGAGTGATTGCCCGAGCAGCAGAGATAATGGAAACATCAATACAAGC GATGAAAAGAAAAGTCAACCTGAAAACTCAACAATCACAGCATCCAACGGATGCTTTATC AGAAGATCTGCTGAGCATCATTGCAAACATGTCTGGATGTCTCCCTTACATGCTGCCCCC AAAATGCCCAAACACTTGCCTGGCGAACAAATACAGGCCCATCACAGGAGCTTGCAACAA CAGAGACCACCCCAGATGGGGCGCCTCCAACACGGCCCTGGCACGATGGCTCCCTCCAGT CTATGAGGACGGCTTCAGTCAGCCCCGAGGCTGGAACCCCGGCTTCTTGTACAACGGGTT CCCACTGCCCCCGGTCCGGGAGGTGACAAGACATGTCATTCAAGTTTCAAATGAGGTTGT CACAGATGATGACCGCTATTCTGACCTCCTGATGGCATGGGGACAATACATCGACCACGA CATCGCGTTCACACCACAGAGCACCAGCAAAGCTGCCTTCGGGGGAGGGGCTGACTGCCA GATGACTTGTGAGAACCAAAACCCATGTTTTCCCATACAACTCCCGGAGGAGGCCCGGCC GGCCGCGGGCACCGCCTGTCTGCCCTTCTACCGCTCTTCGGCCGCCTGCGGCACCGGGGA CCAAGGCGCGCTCTTTGGGAACCTGTCCACGGCCAACCCGCGGCAGCAGATGAACGGGTT GACCTCGTTCCTGGACGCGTCCACCGTGTATGGCAGCTCCCCGGCCCTAGAGAGGCAGCT GCGGAACTGGACCAGTGCCGAAGGGCTGCTCCGCGTCCACGCGCGCCTCCGGGACTCCGG CCGCGCCTACCTGCCCTTCGTGCCGCCACGCGCGCCTGCGGCCTGTGCGCCCGAGCCCGG CATCCCCGGAGAGACCCGCGGGCCCTGCTTCCTGGCCGGAGACGGCCGCGCCAGCGAGGT CCCCTCCCTGACGGCACTGCACACGCTGTGGCTGCGCGAGCACAACCGCCTGGCCGCGGC GCTCAAGGCCCTCAATGCGCACTGGAGCGCGGACGCCGTGTACCAGGAGGCGCGCAAGGT CGTGGGCGCTCTGCACCAGATCATCACCCTGAGGGATTACATCCCCAGGATCCTGGGACC CGAGGCCTTCCAGCAGTACGTGGGTCCCTATGAAGGCTATGACTCCACCGCCAACCCCAC TGTGTCCAACGTGTTCTCCACAGCCGCCTTCCGCTTCGGCCATGCCACGATCCACCCGCT GGTGAGGAGGCTGGACGCCAGCTTCCAGGAGCACCCCGACCTGCCCGGGCTGTGGCTGCA CCAGGCTTTCTTCAGCCCATGGACATTACTCCGTGGAGGTGGTTTGGACCCACTAATACG AGGCCTTCTTGCAAGACCAGCCAAACTGCAGGTGCAGGATCAGCTGATGAACGAGGAGCT GACGGAAAGGCTCTTTGTGCTGTCCAATTCCAGCACCTTGGATCTGGCGTCCATCAACCT GCAGAGGGGCCGGGACCACGGGCTGCCAGGTTACAATGAGTGGAGGGAGTTCTGCGGCCT GCCTCGCCTGGAGACCCCCGCTGACCTGAGCACAGCCATCGCCAGCAGGAGCGTGGCCGA CAAGATCCTGGACTTGTACAAGCATCCTGACAACATCGATGTCTGGCTGGGAGGCTTAGC TGAAAACTTCCTCCCCAGGGCTCGGACAGGGCCCCTGTTTGCCTGTCTCATTGGGAAGCA GATGAAGGCTCTGCGGGACGGTGACTGGTTTTGGTGGGAGAACAGCCACGTCTTCACGGA TGCACAGAGGCGTGAGCTGGAGAAGCACTCCCTGTCTCGGGTCATCTGTGACAACACTGG CCTCACCAGGGTGCCCATGGATGCCTTCCAAGTCGGCAAATTCCCCGAAGACTTTGAGTC TTGTGACAGCATCACTGGCATGAACCTGGAGGCCTGGAGGGAAACCTTTCCTCAAGACGA CAAGTGTGGCTTCCCAGAGAGCGTGGAGAATGGGGACTTTGTGCACTGTGAGGAGTCTGG GAGGCGCGTGCTGGTGTATTCCTGCCGGCACGGGTATGAGCTCCAAGGCCGGGAGCAGCT CACTTGCACCCAGGAAGGATGGGATTTCCAGCCTCCCCTCTGCAAAGATGTGAACGAGTG TGCAGACGGTGCCCACCCCCCCTGCCACGCCTCTGCGAGGTGCAGAAACACCAAAGGCGG CTTCCAGTGTCTCTGCGCGGACCCCTACGAGTTAGGAGACGATGGGAGAACCTGCGTAGA TCCTGCCCCCGCCAAGGGCGTCCGAGAGAGCCCCTGAGCCCGGCCCGGACCAGCGCCCGT GCTCAGGGCAGCTGTGCGCTCCGCGCTGCCTTCTGGTTCTGTGTGATGGATGTGATGCTT GCATGGTGCTGTCCCTGCCCCGCTCCGCCCCTGCTGGGCTCCTGGCTGCCGAACCTGAAG TCAGGGTCCGCCGCAGAACACGTCTTCCCGCTGAGCCCTGCAGCCCCTCAAGCAGCTGGC TGCCTCCGAGGAGCTTCCTCTCCGACAGCTGCCGTGTACCTCCCTGACCTCCCTGGCTGT GACTCAGGCCCTCCGGAGGCACTGGGCCAGGCCGCCGGTGGAGCCTGATGGTGGACGATG GTGGACAGTGACCTTCTCCTTCTAAGGAAGGGACTGAGGGAGGGAAAGTGCCCCCAGAGC ATCTCAGGAGCTGGGAGGTGAACAGCTGGGGATGCTGGCTTCAGTGCTTCCCCCACCACC AGCACCCTTATGATTATACTGCTGCCCCTGCAAAAATGACCATGGAAAATTAGGATGCTG GGCATGACCTTTCTGCATCCCTGACGCACAAGCCTAACTGTTGTTGCACGGAGGCCACAC ACGTCCCTGATGAAAGAGCCCTGCTCCCGTGCAAGCAGCCGTCAGTGCCCTCTCCGTACA GATGGCGCAGCCATCAGTGCCCTCTCTGTACAGACGGAGCAGGCCAGCAGGACCCAGCAC TGTCCCTGGATGCACCAGCTCTGTCACTGCTGGCTGGAACACCCAAAAGGGTGATGGACA TGGCTGTCCCTCAGTTTTCAGAATGACAGCGTGAAACCCAAGCCTGCCTGCATGAGGAAG GGTGGACACAGACAGCAGCAGAGGCCTCGGCTGAGTGGACATGCGCTCAGGTGCTGAGGG CTGAGAGTGACCCAGGAGCAACAGCTGAGCCATATTTACAGCCCCTCCTACGAGCCCTGG CTGGAGGCCAGAGGTTCCAGGGAAGGTGGGCACCAGGGCCCATGTCTGAGAGATTCATAA ACAGGTGCCACGGCTTCTCCTTCCGTCCTCACAGTGACTCACAGACAAGGATGCCAAGGC CTGGAAGATGAGGCATGGCTGTGAGAGGAGCTCACACTCCCCTGGCCTGCGAGAGCTCTG GCCCCGGCCAGCCCGTGTGCTGATCGTATTAGACGGAGTCTCCAGAGAAACAGGAGCAAT CAGAGATGCAGATACTCCGGGAGGCTCCCTCGGGTGACTTGGATCTCCATGTCGCTGGCT GCTCTGCTGATCGGAGGCTTCGCAGGTCTCACCTCGACGGTGATTTGCAGGTGGAGAGTG CTGGGATGGAAGGCCGGGATACTCACAGGCTGCCGAGAGCCCTCTGAGG |
Protein Sequence | >7173 : length: 935 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL TCTQEGWDFQPPLCKDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPI SETGGGTPELRCGKHQAVGTSPQRAAAQDSEQVGHTMPHVSSCHRSGWTGSGCRSSSAGA PCIFLFTPCFLVRSAPSSGRFYLQANDSEPECEPA |