| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7068 |
Name | THRB |
Synonym | C-ERBA-2|C-ERBA-BETA|ERBA2|GRTH|NR1A2|PRTH|THR1|THRB1|THRB2;thyroid hormone receptor, beta;THRB;thyroid hormone receptor, beta |
Definition | nuclear receptor subfamily 1 group A member 2|oncogene ERBA2|thyroid hormone nuclear receptor beta variant 1|thyroid hormone receptor beta|thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) |
Position | 3p24.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | map kinase inactivation of smrt corepressor;PID BioCarta;100032 |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | Gene Expression;Reactome;REACT:71 |
Disease | Thyroid hormone resistance;OMIM |
Disease | PSYCH;GAD |
Disease | ADHD;GAD |
Disease | Thyroid hormone resistance, selective pituitary;OMIM |
Disease | IMMUNE;GAD |
Disease | Thyroid hormone resistance, autosomal recessive;OMIM |
Disease | Hematological and biochemical traits;NHGRI |
Disease | METABOLIC;GAD |
Disease | Graves disease;GAD |
Disease | resistance to thyroid hormone;GAD |
Disease | hormone disturbance;GAD |
External Links | |
Links to Entrez Gene | 7068 |
Links to all GeneRIF Items | 7068 |
Links to iHOP | 7068 |
Sequence Information | |
Nucleotide Sequence | >7068 : length: 7651 CGGCGGGGATTAACTTTGCATGAATAATGTGAGTGCGCTTGGAAAAGAGACCTCCTGCTC CGCGGGCTCGGGGCAAGAGCCCGCAGGCTACCTTCCCCGGGCAGGGGCGCTCAACCCAAC CGGCTCCAGGGCACTGGTAATTTGGCTAGAGGACCGCGCGGAGGCAGCGGGATCTGCGAT TTCCTTCTGGTTGGCTGTCCTGCGTGGGTGCCAAGTTCCACACATGATTTAATGAATAAG AAGGGGGCTTGGAGGCTCATAGCAAAGGTCCTTGAAGAGAGCAAGAAAAAGTCTTCCCAG GAAAAGTGGACACCTGAGTGAGTGTTACAACGAGAAGGGGGGCATCCCAGGCAAGGCAGC TACCAAGCACAGGTGTGAAGTGACTTCACTGTAGGAAGAGGAAATGCAGAAAAACAAACG TCTTGAAGACTGAAAGCCTGTTATTCAAAGAGGTTAGCAGTAGACTGTTGGAAGTAAGGA GATGTCAGTGAAAAAAGGGATCCAGAATGATTACTAACCTATGACTCCCAACAGTATGAC AGAAAATGGCCTTACAGCCTGGGACAAACCGAAGCACTGTCCAGACCGAGAACACGACTG GAAGCTAGTAGGAATGTCTGAAGCCTGCCTACATAGGAAGAGCCATTCAGAGAGGCGCAG CACGTTGAAAAATGAACAGTCGTCGCCACATCTCATCCAGACCACTTGGACTAGCTCAAT ATTCCATCTGGACCATGATGATGTGAACGACCAGAGTGTCTCAAGTGCCCAGACCTTCCA AACGGAGGAGAAGAAATGTAAAGGGTACATCCCCAGTTACTTAGACAAGGACGAGCTCTG TGTAGTGTGTGGTGACAAAGCCACCGGGTATCACTACCGCTGTATCACGTGTGAAGGCTG CAAGGGTTTCTTTAGAAGAACCATTCAGAAAAATCTCCATCCATCCTATTCCTGTAAATA TGAAGGAAAATGTGTCATAGACAAAGTCACGCGAAATCAGTGCCAGGAATGTCGCTTTAA GAAATGCATCTATGTTGGCATGGCAACAGATTTGGTGCTGGATGACAGCAAGAGGCTGGC CAAGAGGAAGCTGATAGAGGAGAACCGGGAGAAAAGACGGCGGGAAGAGCTGCAGAAGTC CATCGGGCACAAGCCAGAGCCCACAGACGAGGAATGGGAGCTCATCAAAACTGTCACCGA AGCCCATGTGGCGACCAACGCCCAAGGCAGCCACTGGAAGCAAAAACGGAAATTCCTGCC AGAAGACATTGGACAAGCACCAATAGTCAATGCCCCAGAAGGTGGAAAGGTTGACTTGGA AGCCTTCAGCCATTTTACAAAAATCATCACACCAGCAATTACCAGAGTGGTGGATTTTGC CAAAAAGTTGCCTATGTTTTGTGAGCTGCCATGTGAAGACCAGATCATCCTCCTCAAAGG CTGCTGCATGGAGATCATGTCCCTTCGCGCTGCTGTGCGCTATGACCCAGAAAGTGAGAC TTTAACCTTGAATGGGGAAATGGCAGTGACACGGGGCCAGCTGAAAAATGGGGGTCTTGG GGTGGTGTCAGACGCCATCTTTGACCTGGGCATGTCTCTGTCTTCTTTCAACCTGGATGA CACTGAAGTAGCCCTCCTTCAGGCCGTCCTGCTGATGTCTTCAGATCGCCCGGGGCTTGC CTGTGTTGAGAGAATAGAAAAGTACCAAGATAGTTTCCTGCTGGCCTTTGAACACTATAT CAATTACCGAAAACACCACGTGACACACTTTTGGCCAAAACTCCTGATGAAGGTGACAGA TCTGCGGATGATAGGAGCCTGCCATGCCAGCCGCTTCCTGCACATGAAGGTGGAATGCCC CACAGAACTCTTCCCCCCTTTGTTCTTGGAAGTGTTCGAGGATTAGACTGACTGGATTCA TTCTCATAATTCCTACAGCACTACTGGGTGTCATTTCATTCCATTGCCTAGCTCTTTTTT GTTTGTTTCTTTGTGTTGGGAGGGATTATTTGGGAGGGAAAAGGGAAGTAGTCCTTGGCA TAGACATGGATGAAATTGCCCCTTGAATGCGGGTACTTGAAACTATTGCATTTCGTTCTC CGGTCCTGTGATGTGAATGCTCTGAAGGTTTTATGGTTGTGGAGGTGGGGTGGGGGACAA TCATTAACTCACCAGCACCAAGCATCACCAGCTCCCACCCGTCCCTGGTCCAAGACTTGA GTCAGCAAAATGGCGCCACAGGACACTAAAGAAGCCTTAAAACCAAGATAATACGACCAC CTCCACCCAATCCTGATGTTCGCAGGGCTGAAGTTAACAGAGCACAGACCACCTTTAGTT AGATGTGGCTTTCAGCCTTTTAGGGAAAGACTCGAACAAATTTTCATCTATTCAAGAGCA TGCTGTTTGCAGCACTCTTTATGGTCTCCTAGGAGCATAACTTGGAATGTACAGGAATAT TTGTGTCCTAAAAAAATCAGCTGCCCTTCCAATATCATTTTTATAACGTTATGGTTTAAT TCAAGTTATACAAAGGTGTGACTCAAGGATGTGCAGGTATTGACTGATGGAGGCCAACAA GGAAAATATTTTTTTTCAGTGAGCCCAGAGAAATTAGAAATCTTCACCAATGTCAGTGAC TGCATGGTTTCCAAAAATTCACATAGTATTACCTCACAGTAGGAAGGCTTCTTTCCCATT TAGGCTCAGAGAACACTTTTACAGAAATCAAACCTATTTACAGGGTGGCACCCCTTTTCT GTGGCATCTGATCTGTCATCTCCCAAGCTCCTGAAGTTCTTTATCCAGGTTGTATCTTTG CTGAGCTGACAACAGATTTCTCTATGGATCAAATATTCTAATCAAGGAAAGATACGGTGA AACTTCAGTCTTCTTCTGGAGAAATGCTGAGGCGAGATTAGTGCAGCTACATTCTGAGTT GAAGGAAATGCAGTGTTCTGAGGGCCCCTTTGTGTCCTGATGGCTGGAGGACGCTTCCTC CTGGTTAGATCCTCAAGCTCCTTGCCTCATTGACAAATGTCTCCTAGTCCCCTTTTTCCC TCTGACTCTGAGGAACTAAATAGCTTGACTATCTCTAAACAGAGACTGGCCCTGCCACTG ACCCTCCTGTCCCTCTCATAGCATACCCTGACAGATACTCAATAGAAAACACCTGCAGAC CATGTGCACACTTAACTTTCCTGCCCAACCTGCCTCCCCAACGGCCCATGCTAGAATAGC TTGTGCCCAGAAAACAAACAGTGACACTTCATCTCTTCAGCGTCAGAAAATGGGCATAGA ATGTACCCATGCAATTGAATGTATCTCATTCTCCACTGGCATAGTAGATATAAACTATTC CTTTGCCTACCTTTTACTGCCTTATCCTGGAAATATTGGGGAAAATAAGCCATATCAGTG AGATTTACCTAAAAACAAAGGAAGGAAAGTCACTATGGAAACCAAGTAGATGCTTTTTGT AAGTTTGGTGGAGCATAACTGGCCCAGAAGTCTGGGTGCCTGAGTTCTAGTTCGTGCTCT GTCAACTGGTAGATTTGTAATTCTAGGTCTTGGTTTTCTTACCTGGTGAATAAGTCATGA TCTCTAAAACCCTTCCTGCCCTTAATATTGTCTGAATTTCAAGGGGAAAAAAAAAATCTG GTTCCTTTAATTATTTTTTTTTAACACTTAAATTCCTAACTTTATTAGACAAGAAGTATG GCCCACTTAACAGTTAAGGAACGTAAATTTGTTATTGGCTCGAAATAATAATTTGACACA ATACTAGTCAACCATTTAGAGGCCTTGGAAAAAGAAGAGGAACAGCACTGAAAATTCCAA GTATGATTGGAAATTATCTGGGAGCGGGGAATTAAATATTCAATGCATGAAAGCAATTGT ACTGGCTTCTGGGAAAAAGGAAACAAGAACATTGCTATGGAACTTGTTACCCAGAGAAAG GAAGTGAAAAGATTTACAATTATAAGCACGAAATTCATTGGCAGATTACCTGCTTTATCT ACAGACAGATTGTTTTGGGGTTTGGTTTTGTCTAGGCAGCCTCTGGCCAGGCTCCTTAAT TGCTTGCTCTGCTAATATTTCAGCTTCCTCTCTTGACTCCTTGAGGAACCAACCGCTCTT TGGAAGACAAACACTTAGCCACCTCTGTGCTCCAGGGTAACCCTGAGAAGCTCTGCTGTC TGGGGCAAGCTTTCTTTCCAAAGGGAATGAGAGGAAGGCAAGCAGGCAGGGTCCTGCAGC GTCAGGCCTTCTGGGGAAAGTTTCCTCATTTTGTTTGACAGGGTCCTCAGTACATCAGAC ACCCAGATTTGAATATAAGTTCAGAGCCTGATCTCAAGCTAAATCAGAATGCTTTGGGGA CTAACCATGATCGAGAATTGGCCAAATAGTATGGCATATAAACAGCCATCCAGCCAGCCG CAAGTAAAGGAACGTTTGATCCTTGGCACCTTAAATGATTGATTGCCTTCAATAGGCAAA CTGCTGGTCTGGAAATCTCGTTGAAGGCTGAATACTTCATGCGGAGTAGGACAAGCCTTA GCCCACCTTCAGGTTGAAAGGAAAGGCCATAGGACTCAAAAGATAATGACTCTGAAACTA AACTCCTTCCTTCTGAAGCTGACAGAGGTACTTAGTGCATCTCAAGACTCCATCTCATAA AACTCATTTGTGAGGGATTTGCTCTAGATTTTTCTAAACATTTTTTCATCTATTGTCCAG ACTTGCAAATCCAGTGTGGACCTGATGGAGATACCCTTCACACCTGCGCTCCCACCCCCT CGGCAGGGAGACGTCTCAGTAGAGGAGAACACACCCATTATGCTGGGATTTGTATTTATA AATCACTTCCCTTTTAGGGATGAGCGGTGTGGGGCGTGTGTGCGTGTGAGTGTATGCGCG TGCGTGTGTGACCCTCAAGTGTACTTTGCTCAATTTAGACGTGCAGTATTTCCAGAAACA ATGAAAAAAGTAAGATGTTTTCTTCTTTATGATTCTGCTCAAAACACCACGTGCCGCCTC AGAGCTTTTTCTAGAGCCTCGGTCCTCAATGACGCGCTTGACCTGTTGATGCCTCAGCCC AGCGAAGCCCCTCACCTGTGCCCCGGGCGACAGCTCTTCAGTGTGCAGTGCAGGCCTGGG GTGGACTGCCAGGCCTTCGCTCTGTGCCAGCAACGCCGTTCTTGTTGCTCCTCCATGAAC AGGGGTACAAGCCCTGGCCCCTCCTCGACACTAAGCCCCCCACAGACTCAGCCTCCAAGG AACCGCTGAGCACCCTTGAAGCATGTCATTGTCAGTGATACCTTTTTATTCTATGGAACT CTAACCTATTCGTGTCATATTGACCTTTTGCTGCATGAGTCATAAATTATGAAATCAGTC TTACAGTTTTTGAAATGTAGCCAGCATTTGTAAGGCTAAACCTTTTTCATGAACTGAATT TAAGTGAATAACCAAGCCACAGTTCCTCCTCAAATGGAGAGTGATGATCGACATTTGAAT CTCTTTGCCCTTTCCAACGGCTATGGCATCAGGTTCTAAAATAAGCTCGTAATTTTTCCT GTTATTTTAATAATATGGAAATATTAGCATAGTGTTTCTTTTGATAGTGATAGACTATAA TCCATATTTAAATTTTATAGAGAAGAAATTTTATTGTACTGTGATGTAGATATTTATTAT CCAGGTAAGGATTTGCCCGGTGTGTATTTTTTACAATTGAGACATTTTACTTTAATCTTT AAAAAAAATGCATTAAAAACACACTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCAG ACTGGGGGAAAAAAGGTTTGGCCTTATCACAGAATTTTTACTGTGCTGTATAAATGTTTG CAAATGCGAAAAGTGTGCATTTATAGTGTGTTTCCACATTAATTAATGCCGCCTTCAAGA GCAATATTGTGCAGGTAAAACGCTGTTTGTGGCTTTCTGTTGCACAGTTAAAGCTGACCC ACCCTATGCACAAGACAATCAAATATAAATCTGTCCTCCTCAGGATGCAGATAATACTCA TGTAAATTATGGAGCACAATGTAAGACAAAAGGAGACACTTTACATATGTATTGTTGATA CAGAAATTATCAGGGCATGAATGAGCTGATGTGACATTATGCCACTTCTTTCTTTTGGTT CTCCCTTATTAACTTGGCATTTTTAATTTGACCATAGAGCCAAATTAGTTCTCCATGCTT TCTTCGTAGAAAATCCTTTTTTTTCCCATAATGTTTTCATGCCCTGAGAATCAGAAAAAT ACTACAGAATAGAAAAAGATTTACAGTCATTGGAAGATTTGTGTTTTGCAAACAGTGTTA AGTGATATTGCTAGATGGTGATATTTTTTTCAGCCTAAAACTCTGTTGAAATCTGTGATC AAAATGTTTTAAACTATCCAAAAAAAATTTGTATATTTGGGAAAAATGGATTTTTACATA GCTTTTGTATGCAGATATAAAACTGTAATTATGAATATAGTGGGCGTAGATAAACTCATA AGCTTAAATTCTAAAAAAGAAAAAGCTTATAACAGATATATTTTCCTGTCTCTTTCTTTA AATATTATTATTTTCTACATAGGCAAAGAGTTGCCTGCTCTTCTCACTTCAGCTGCTGCC AAAAGACGGAACCACGGATGTAAGGACATTTATTTCATAAATAAACATCTACTAGAATAA GCAAATTTACTTGAGAAGAAACTATGGAGGGAGAGAAGAAACTAAGTAAAATGCTGATGG GGGGTTACCTCTTTGGAAGGGGCCACAAAGATGAAGGGAGGAGAGAGGTGAAGTTTTGCA GCTCAAGGACAACATTCATCTTCTCATCTCAAATTATTCAGGAATATTACTAATGGAATT ATGTTAACATCAGCTGCCAACATATATCTCAATCTCTGTTGCCCTGAACACATGTTAATT GAGATTCTTTCTATGACAAGTAACAAAAAGCTAACTCAAACTGGCTTAAGCAGAAAGCTA ATTATTGACTTTAATATCTGGGATCTAGGGTATTGCATACCAAAGCTTCAGGCATGGCTG GATCTGGGTGCACTTACTCAGTATTCTCAGGAAGCTCCTTTTTTTGTCATTCATGTAGAC TTAACATTCACATGGCCTTTCACCTTACGGTGGCCTCCAATAGCTCCAGGATGAGCTTTA CAGCTCCAAATATAGTGAAAGGAGAATTTCTTTTCTCCAACAATTCTAATGAAAATTCTG GCCTAATTCTCACTGGCCCAAGTTCAGTCATGTGCCCATTCCTGAGCCAATCACTGTGGT GAGGAAAACAGATGCATAACCAACCTTATCCTCAGGAATCCTGGAACTGGGTGAGGGGAA AGAGGGACAGTCAGCTTCATCTAAACTATGGACTGAGAGTTGAGGCAAGATGATTCCTGA AAGAAAATTCTAAGTCTTGCTGCTATAAGTGGAAGAGAATGGTGGGCAAGCAAAAGCAAC CAGTGCCCACACCAAAGGTAAATCTAAAACAACATCCCATTTCAGTACAGCAAGCGGTTC TCCTTCACACAGAGGAAGCTCATCTCCAAGTTTTTATTTGGCCAGGACATGAACCAAATA AACACCTTCCAAAGAAAAAAAAAAAAAAAAA |
Protein Sequence | >7068 : length: 461 MTPNSMTENGLTAWDKPKHCPDREHDWKLVGMSEACLHRKSHSERRSTLKNEQSSPHLIQ TTWTSSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYR CITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVL DDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWK QKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCED QIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSL SSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPK LLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED |