| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7057 |
Name | THBS1 |
Synonym | THBS|THBS-1|TSP|TSP-1|TSP1;thrombospondin 1;THBS1;thrombospondin 1 |
Definition | thrombospondin-1|thrombospondin-1p180 |
Position | 15q15 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Malaria;KEGG PATHWAY;hsa05144 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | Integrin cell surface interactions;PID Reactome;500004 |
Pathway | Integrin cell surface interactions;Reactome;REACT:13552 |
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | Syndecan-4-mediated signaling events;PID Curated;200115 |
Pathway | ECM-receptor interaction;KEGG PATHWAY;hsa04512 |
Pathway | p53 signaling pathway;KEGG PATHWAY;hsa04115 |
Pathway | TGF-beta signaling pathway;KEGG PATHWAY;hsa04350 |
Pathway | Phagosome;KEGG PATHWAY;hsa04145 |
Pathway | Bladder cancer;KEGG PATHWAY;hsa05219 |
Disease | brain hemorrhage;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Stroke;GAD |
Disease | myocardial infarct;GAD |
Disease | stroke, lacunar;GAD |
External Links | |
Links to Entrez Gene | 7057 |
Links to all GeneRIF Items | 7057 |
Links to iHOP | 7057 |
Sequence Information | |
Nucleotide Sequence | >7057 : length: 7253 AGCCGCTGCGCCCGAGCTGGCCTGCGAGTTCAGGGCTCCTGTCGCTCTCCAGGAGCAACC TCTACTCCGGACGCACAGGCATTCCCCGCGCCCCTCCAGCCCTCGCCGCCCTCGCCACCG CTCCCGGCCGCCGCGCTCCGGTACACACAGGATCCCTGCTGGGCACCAACAGCTCCACCA TGGGGCTGGCCTGGGGACTAGGCGTCCTGTTCCTGATGCATGTGTGTGGCACCAACCGCA TTCCAGAGTCTGGCGGAGACAACAGCGTGTTTGACATCTTTGAACTCACCGGGGCCGCCC GCAAGGGGTCTGGGCGCCGACTGGTGAAGGGCCCCGACCCTTCCAGCCCAGCTTTCCGCA TCGAGGATGCCAACCTGATCCCCCCTGTGCCTGATGACAAGTTCCAAGACCTGGTGGATG CTGTGCGGGCAGAAAAGGGTTTCCTCCTTCTGGCATCCCTGAGGCAGATGAAGAAGACCC GGGGCACGCTGCTGGCCCTGGAGCGGAAAGACCACTCTGGCCAGGTCTTCAGCGTGGTGT CCAATGGCAAGGCGGGCACCCTGGACCTCAGCCTGACCGTCCAAGGAAAGCAGCACGTGG TGTCTGTGGAAGAAGCTCTCCTGGCAACCGGCCAGTGGAAGAGCATCACCCTGTTTGTGC AGGAAGACAGGGCCCAGCTGTACATCGACTGTGAAAAGATGGAGAATGCTGAGTTGGACG TCCCCATCCAAAGCGTCTTCACCAGAGACCTGGCCAGCATCGCCAGACTCCGCATCGCAA AGGGGGGCGTCAATGACAATTTCCAGGGGGTGCTGCAGAATGTGAGGTTTGTCTTTGGAA CCACACCAGAAGACATCCTCAGGAACAAAGGCTGCTCCAGCTCTACCAGTGTCCTCCTCA CCCTTGACAACAACGTGGTGAATGGTTCCAGCCCTGCCATCCGCACTAACTACATTGGCC ACAAGACAAAGGACTTGCAAGCCATCTGCGGCATCTCCTGTGATGAGCTGTCCAGCATGG TCCTGGAACTCAGGGGCCTGCGCACCATTGTGACCACGCTGCAGGACAGCATCCGCAAAG TGACTGAAGAGAACAAAGAGTTGGCCAATGAGCTGAGGCGGCCTCCCCTATGCTATCACA ACGGAGTTCAGTACAGAAATAACGAGGAATGGACTGTTGATAGCTGCACTGAGTGTCACT GTCAGAACTCAGTTACCATCTGCAAAAAGGTGTCCTGCCCCATCATGCCCTGCTCCAATG CCACAGTTCCTGATGGAGAATGCTGTCCTCGCTGTTGGCCCAGCGACTCTGCGGACGATG GCTGGTCTCCATGGTCCGAGTGGACCTCCTGTTCTACGAGCTGTGGCAATGGAATTCAGC AGCGCGGCCGCTCCTGCGATAGCCTCAACAACCGATGTGAGGGCTCCTCGGTCCAGACAC GGACCTGCCACATTCAGGAGTGTGACAAGAGATTTAAACAGGATGGTGGCTGGAGCCACT GGTCCCCGTGGTCATCTTGTTCTGTGACATGTGGTGATGGTGTGATCACAAGGATCCGGC TCTGCAACTCTCCCAGCCCCCAGATGAACGGGAAACCCTGTGAAGGCGAAGCGCGGGAGA CCAAAGCCTGCAAGAAAGACGCCTGCCCCATCAATGGAGGCTGGGGTCCTTGGTCACCAT GGGACATCTGTTCTGTCACCTGTGGAGGAGGGGTACAGAAACGTAGTCGTCTCTGCAACA ACCCCACACCCCAGTTTGGAGGCAAGGACTGCGTTGGTGATGTAACAGAAAACCAGATCT GCAACAAGCAGGACTGTCCAATTGATGGATGCCTGTCCAATCCCTGCTTTGCCGGCGTGA AGTGTACTAGCTACCCTGATGGCAGCTGGAAATGTGGTGCTTGTCCCCCTGGTTACAGTG GAAATGGCATCCAGTGCACAGATGTTGATGAGTGCAAAGAAGTGCCTGATGCCTGCTTCA ACCACAATGGAGAGCACCGGTGTGAGAACACGGACCCCGGCTACAACTGCCTGCCCTGCC CCCCACGCTTCACCGGCTCACAGCCCTTCGGCCAGGGTGTCGAACATGCCACGGCCAACA AACAGGTGTGCAAGCCCCGTAACCCCTGCACGGATGGGACCCACGACTGCAACAAGAACG CCAAGTGCAACTACCTGGGCCACTATAGCGACCCCATGTACCGCTGCGAGTGCAAGCCTG GCTACGCTGGCAATGGCATCATCTGCGGGGAGGACACAGACCTGGATGGCTGGCCCAATG AGAACCTGGTGTGCGTGGCCAATGCGACTTACCACTGCAAAAAGGATAATTGCCCCAACC TTCCCAACTCAGGGCAGGAAGACTATGACAAGGATGGAATTGGTGATGCCTGTGATGATG ACGATGACAATGATAAAATTCCAGATGACAGGGACAACTGTCCATTCCATTACAACCCAG CTCAGTATGACTATGACAGAGATGATGTGGGAGACCGCTGTGACAACTGTCCCTACAACC ACAACCCAGATCAGGCAGACACAGACAACAATGGGGAAGGAGACGCCTGTGCTGCAGACA TTGATGGAGACGGTATCCTCAATGAACGGGACAACTGCCAGTACGTCTACAATGTGGACC AGAGAGACACTGATATGGATGGGGTTGGAGATCAGTGTGACAATTGCCCCTTGGAACACA ATCCGGATCAGCTGGACTCTGACTCAGACCGCATTGGAGATACCTGTGACAACAATCAGG ATATTGATGAAGATGGCCACCAGAACAATCTGGACAACTGTCCCTATGTGCCCAATGCCA ACCAGGCTGACCATGACAAAGATGGCAAGGGAGATGCCTGTGACCACGATGATGACAACG ATGGCATTCCTGATGACAAGGACAACTGCAGACTCGTGCCCAATCCCGACCAGAAGGACT CTGACGGCGATGGTCGAGGTGATGCCTGCAAAGATGATTTTGACCATGACAGTGTGCCAG ACATCGATGACATCTGTCCTGAGAATGTTGACATCAGTGAGACCGATTTCCGCCGATTCC AGATGATTCCTCTGGACCCCAAAGGGACATCCCAAAATGACCCTAACTGGGTTGTACGCC ATCAGGGTAAAGAACTCGTCCAGACTGTCAACTGTGATCCTGGACTCGCTGTAGGTTATG ATGAGTTTAATGCTGTGGACTTCAGTGGCACCTTCTTCATCAACACCGAAAGGGACGATG ACTATGCTGGATTTGTCTTTGGCTACCAGTCCAGCAGCCGCTTTTATGTTGTGATGTGGA AGCAAGTCACCCAGTCCTACTGGGACACCAACCCCACGAGGGCTCAGGGATACTCGGGCC TTTCTGTGAAAGTTGTAAACTCCACCACAGGGCCTGGCGAGCACCTGCGGAACGCCCTGT GGCACACAGGAAACACCCCTGGCCAGGTGCGCACCCTGTGGCATGACCCTCGTCACATAG GCTGGAAAGATTTCACCGCCTACAGATGGCGTCTCAGCCACAGGCCAAAGACGGGTTTCA TTAGAGTGGTGATGTATGAAGGGAAGAAAATCATGGCTGACTCAGGACCCATCTATGATA AAACCTATGCTGGTGGTAGACTAGGGTTGTTTGTCTTCTCTCAAGAAATGGTGTTCTTCT CTGACCTGAAATACGAATGTAGAGATCCCTAATCATCAAATTGTTGATTGAAAGACTGAT CATAAACCAATGCTGGTATTGCACCTTCTGGAACTATGGGCTTGAGAAAACCCCCAGGAT CACTTCTCCTTGGCTTCCTTCTTTTCTGTGCTTGCATCAGTGTGGACTCCTAGAACGTGC GACCTGCCTCAAGAAAATGCAGTTTTCAAAAACAGACTCAGCATTCAGCCTCCAATGAAT AAGACATCTTCCAAGCATATAAACAATTGCTTTGGTTTCCTTTTGAAAAAGCATCTACTT GCTTCAGTTGGGAAGGTGCCCATTCCACTCTGCCTTTGTCACAGAGCAGGGTGCTATTGT GAGGCCATCTCTGAGCAGTGGACTCAAAAGCATTTTCAGGCATGTCAGAGAAGGGAGGAC TCACTAGAATTAGCAAACAAAACCACCCTGACATCCTCCTTCAGGAACACGGGGAGCAGA GGCCAAAGCACTAAGGGGAGGGCGCATACCCGAGACGATTGTATGAAGAAAATATGGAGG AACTGTTACATGTTCGGTACTAAGTCATTTTCAGGGGATTGAAAGACTATTGCTGGATTT CATGATGCTGACTGGCGTTAGCTGATTAACCCATGTAAATAGGCACTTAAATAGAAGCAG GAAAGGGAGACAAAGACTGGCTTCTGGACTTCCTCCCTGATCCCCACCCTTACTCATCAC CTGCAGTGGCCAGAATTAGGGAATCAGAATCAAACCAGTGTAAGGCAGTGCTGGCTGCCA TTGCCTGGTCACATTGAAATTGGTGGCTTCATTCTAGATGTAGCTTGTGCAGATGTAGCA GGAAAATAGGAAAACCTACCATCTCAGTGAGCACCAGCTGCCTCCCAAAGGAGGGGCAGC CGTGCTTATATTTTTATGGTTACAATGGCACAAAATTATTATCAACCTAACTAAAACATT CCTTTTCTCTTTTTTCCTGAATTATCATGGAGTTTTCTAATTCTCTCTTTTGGAATGTAG ATTTTTTTTAAATGCTTTACGATGTAAAATATTTATTTTTTACTTATTCTGGAAGATCTG GCTGAAGGATTATTCATGGAACAGGAAGAAGCGTAAAGACTATCCATGTCATCTTTGTTG AGAGTCTTCGTGACTGTAAGATTGTAAATACAGATTATTTATTAACTCTGTTCTGCCTGG AAATTTAGGCTTCATACGGAAAGTGTTTGAGAGCAAGTAGTTGACATTTATCAGCAAATC TCTTGCAAGAACAGCACAAGGAAAATCAGTCTAATAAGCTGCTCTGCCCCTTGTGCTCAG AGTGGATGTTATGGGATTCTTTTTTTCTCTGTTTTATCTTTTCAAGTGGAATTAGTTGGT TATCCATTTGCAAATGTTTTAAATTGCAAAGAAAGCCATGAGGTCTTCAATACTGTTTTA CCCCATCCCTTGTGCATATTTCCAGGGAGAAGGAAAGCATATACACTTTTTTCTTTCATT TTTCCAAAAGAGAAAAAAATGACAAAAGGTGAAACTTACATACAAATATTACCTCATTTG TTGTGTGACTGAGTAAAGAATTTTTGGATCAAGCGGAAAGAGTTTAAGTGTCTAACAAAC TTAAAGCTACTGTAGTACCTAAAAAGTCAGTGTTGTACATAGCATAAAAACTCTGCAGAG AAGTATTCCCAATAAGGAAATAGCATTGAAATGTTAAATACAATTTCTGAAAGTTATGTT TTTTTTCTATCATCTGGTATACCATTGCTTTATTTTTATAAATTATTTTCTCATTGCCAT TGGAATAGATATCTCAGATTGTGTAGATATGCTATTTAAATAATTTATCAGGAAATACTG CCTGTAGAGTTAGTATTTCTATTTTTATATAATGTTTGCACACTGAATTGAAGAATTGTT GGTTTTTTCTTTTTTTTGTTTTGTTTTTTTTTTTTTTTTTTTTTGCTTTTGACCTCCCAT TTTTACTATTTGCCAATACCTTTTTCTAGGAATGTGCTTTTTTTTGTACACATTTTTATC CATTTTACATTCTAAAGCAGTGTAAGTTGTATATTACTGTTTCTTATGTACAAGGAACAA CAATAAATCATATGGAAATTTATATTTATACTTACTGTATCCATGCTTATTTGTTCTCTA CTGGCTTTATGTCATGAAGTATATGCGTAAATACCATTCATAAATCAATATAGCATATAC AAAAATAAATTACAGTAAGTCATAGCAACATTCACAGTTTGTATGTGATTGAGAAAGACT GAGTTGCTCAGGCCTAGGCTTAGAATTTGCTGCGTTTGTGGAATAAAAGAACAAAATGAT ACATTAGCCTGCCATATCAAAAACATATAAAAGAGAAATTATCCCTAAGTCAAGGGCCCC CATAAGAATAAAATTTCTTATTAAGGTCATTAGATGTCATTGAATCCTTTTCAAAGTGCA GTATGAAAACAAAGGGAAAAACACTGAAGCACACGCAACTCTCACAGCGACATTTTCTGA CCCACGAATGATGCCTTGGGTGGGCAACACGATTGCATGTTGTGGAGACACTTCGGAAGT AAATGTGGATGAGGGAGGAGCTGTCCTTGCAATGTTGAGCCAAGCATTACAGATACCTCC TCTTGAAGAAGGAATAATAAGTTTAATCAAAAAAGAAGACTAAAAAATGTAAAATTTGGA AGGAATCCATAAATGCGTGTGTGTCTAAATACAAATTATCATGTGAAGAAAAGGCCCAAG TGTACCAATAAGCAGACCTTGATTTTTGGATGGGCTAATTATGAATGTGGAATACTGACC AGTTAATTTCCAGTTTTAATGAAAACAGATCAAAGAAGAAATTTTATGAGTAGGTTAAAG GTCTGGCTTTGAGGTCTATTAAACACTAGAAAGGACTGGCTGGGTGAGATAAAATCTTCC TTGTTGATTTTCACTCTCATTCTATAAATACTCATCTTTCTGAGTAGCCATGATCACATA CAAATGTAAATTGCCAAATCATTTTATAGTACCAAGGTGAAGAAGCAGGAACTAGAAAGT GTTGATAATAGCTGTGGAGTTAGGAAAACTGATGTGAAGGAAATAATTCTTTGAAATGGC AAAGAATTAAATACCATCATTCATTATCAGAAGAGTTCAACGTTTGAAGTGCTGGGAGAT AATTCTAATTCATTCTTGGATAGTGAAGCAAAACTGATTGAAAATACCAAGATAAGACAG AAAAAGTGACTGGAAAGAGGAGCTTTTCTTCCAGGCATGTTCCAGTTTCACCCTAAGACT GACCTTCAAATAATCAGGTTGTACTGAAATAAAGGACTTGTTAAAAATTAAAATTATGTC ATCGAGATGATAGCTTTTTTCCTCCTCCAACAGTTTATTGTCATGTGTTGTGGGAGAGCT CGAGTGAAGAGCAATAAACTCCAGGTCTTATAAGAATGTACATACAATAAAGGTGGTGCC AGCAGTTTTTTTTTTTCTAAAGAGTCACATGTAGAAAAGCCTCCAGTATTAAGCTCCTGA ATTCATTCCTTAAATAAATTGGCTCTCTCTCTCTTCTATAAAAAAAAAAAAAA |
Protein Sequence | >7057 : length: 1170 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD VPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLL TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK VTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQT RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQI CNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACF NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKN AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN DGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRF QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD KTYAGGRLGLFVFSQEMVFFSDLKYECRDP |