| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7054 |
Name | TH |
Synonym | DYT14|DYT5b|TYH;tyrosine hydroxylase;TH;tyrosine hydroxylase |
Definition | dystonia 14|tyrosine 3-hydroxylase|tyrosine 3-monooxygenase |
Position | 11p15.5 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | p38 signaling mediated by MAPKAP kinases;PID Curated;200135 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | Tyrosine metabolism;KEGG PATHWAY;hsa00350 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Alpha-synuclein signaling;PID Curated;200187 |
Pathway | Metabolism of amino acids and derivatives;Reactome;REACT:13 |
Pathway | ATF-2 transcription factor network;PID Curated;200116 |
Pathway | AP-1 transcription factor network;PID Curated;200118 |
Pathway | Adrenaline and noradrenaline biosynthesis;PANTHER;P00001 |
Pathway | catecholamine biosynthesis;BioCyc;PWY66-301 |
Pathway | Parkinson's disease;KEGG PATHWAY;hsa05012 |
Pathway | Hormone biosynthesis;Reactome;REACT:15314 |
Disease | Tobacco Use Disorder;GAD |
Disease | alcohol-withdrawal delirium;GAD |
Disease | Segawa syndrome, recessive;OMIM |
Disease | obesity;GAD |
Disease | triglycerides;GAD |
Disease | hypertension;GAD |
Disease | mood disorder.;GAD |
Disease | prostate cancer;GAD |
Disease | catecholamine turnover;GAD |
Disease | blood pressure;GAD |
Disease | alcoholism;GAD |
Disease | METABOLIC;GAD |
Disease | Insulin Resistance;GAD |
Disease | PSYCH;GAD |
Disease | CHEMDEPENDENCY;GAD |
Disease | left ventricular structure;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | insulin;GAD |
Disease | CANCER;GAD |
Disease | nicotine dependence;GAD |
Disease | left ventricular function;GAD |
Disease | blood pressure, arterial;GAD |
Disease | body mass;GAD |
Disease | schizophrenia;GAD |
External Links | |
Links to Entrez Gene | 7054 |
Links to all GeneRIF Items | 7054 |
Links to iHOP | 7054 |
Sequence Information | |
Nucleotide Sequence | >7054 : length: 2161 TGCCAGAAAGCCCCTCCCTGTGTGCTCTCTTGAGGGCTGTGGGGCCAAGGGGACCCTGGC TGTCTCAGCCCCCCGCAGAGCACGAGCCCCTGGTCCCCGCAAGCCCGCGGGCTGAGGATG ATTCAGACAGGGCTGGGGAGTGAAGGCAATTAGATTCCACGGACGAGCCCTTTCTCCTGC GCCTCCCTCCTTCCTCACCCACCCCCGCCTCCATCAGGCACAGCAGGCAGGGGTGGGGGA TGTAAGGAGGGGAAGGTGGGGGACCCAGAGGGGGCTTTGACGTCAGCTCAGCTTATAAGA GGCTGCTGGGCCAGGGCTGTGGAGACGGAGCCCGGACCTCCACACTGAGCCATGCCCACC CCCGACGCCACCACGCCACAGGCCAAGGGCTTCCGCAGGGCCGTGTCTGAGCTGGACGCC AAGCAGGCAGAGGCCATCATGGTAAGAGGGCAGTCCCCGCGGTTCATTGGGCGCAGGCAG AGCCTCATCGAGGACGCCCGCAAGGAGCGGGAGGCGGCGGTGGCAGCAGCGGCCGCTGCA GTCCCCTCGGAGCCCGGGGACCCCCTGGAGGCTGTGGCCTTTGAGGAGAAGGAGGGGAAG GCCGTGCTAAACCTGCTCTTCTCCCCGAGGGCCACCAAGCCCTCGGCGCTGTCCCGAGCT GTGAAGGTGTTTGAGACGTTTGAAGCCAAAATCCACCATCTAGAGACCCGGCCCGCCCAG AGGCCGCGAGCTGGGGGCCCCCACCTGGAGTACTTCGTGCGCCTCGAGGTGCGCCGAGGG GACCTGGCCGCCCTGCTCAGTGGTGTGCGCCAGGTGTCAGAGGACGTGCGCAGCCCCGCG GGGCCCAAGGTCCCCTGGTTCCCAAGAAAAGTGTCAGAGCTGGACAAGTGTCATCACCTG GTCACCAAGTTCGACCCTGACCTGGACTTGGACCACCCGGGCTTCTCGGACCAGGTGTAC CGCCAGCGCAGGAAGCTGATTGCTGAGATCGCCTTCCAGTACAGGCACGGCGACCCGATT CCCCGTGTGGAGTACACCGCCGAGGAGATTGCCACCTGGAAGGAGGTCTACACCACGCTG AAGGGCCTCTACGCCACGCACGCCTGCGGGGAGCACCTGGAGGCCTTTGCTTTGCTGGAG CGCTTCAGCGGCTACCGGGAAGACAATATCCCCCAGCTGGAGGACGTCTCCCGCTTCCTG AAGGAGCGCACGGGCTTCCAGCTGCGGCCTGTGGCCGGCCTGCTGTCCGCCCGGGACTTC CTGGCCAGCCTGGCCTTCCGCGTGTTCCAGTGCACCCAGTATATCCGCCACGCGTCCTCG CCCATGCACTCCCCTGAGCCGGACTGCTGCCACGAGCTGCTGGGGCACGTGCCCATGCTG GCCGACCGCACCTTCGCGCAGTTCTCGCAGGACATTGGCCTGGCGTCCCTGGGGGCCTCG GATGAGGAAATTGAGAAGCTGTCCACGCTGTACTGGTTCACGGTGGAGTTCGGGCTGTGT AAGCAGAACGGGGAGGTGAAGGCCTATGGTGCCGGGCTGCTGTCCTCCTACGGGGAGCTC CTGCACTGCCTGTCTGAGGAGCCTGAGATTCGGGCCTTCGACCCTGAGGCTGCGGCCGTG CAGCCCTACCAAGACCAGACGTACCAGTCAGTCTACTTCGTGTCTGAGAGCTTCAGTGAC GCCAAGGACAAGCTCAGGAGCTATGCCTCACGCATCCAGCGCCCCTTCTCCGTGAAGTTC GACCCGTACACGCTGGCCATCGACGTGCTGGACAGCCCCCAGGCCGTGCGGCGCTCCCTG GAGGGTGTCCAGGATGAGCTGGACACCCTTGCCCATGCGCTGAGTGCCATTGGCTAGGTG CACGGCGTCCCTGAGGGCCCTTCCCAACCTCCCCTGGTCCTGCACTGTCCCGGAGCTCAG GCCCTGGTGAGGGGCTGGGTCCCGGGTGCCCCCCATGCCCTCCCTGCTGCCAGGCTCCCA CTGCCCCTGCACCTGCTTCTCAGCGCAACAGCTGTGTGTGCCCGTGGTGAGGTTGTGCTG CCTGTGGTGAGGTCCTGTCCTGGCTCCCAGGGTCCTGGGGGCTGCTGCACTGCCCTCCGC CCTTCCCTGACACTGTCTGCTGCCCCAATCACCGTCACAATAAAAGAAACTGTGGTCTCT A |
Protein Sequence | >7054 : length: 528 MPTPDATTPQAKGFRRAVSELDAKQAEAIMVRGQGAPGPSLTGSPWPGTAAPAASYTPTP RSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPR ATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVR QVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEI AFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNI PQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCC HELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYG AGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYAS RIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG |