| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6916 |
Name | TBXAS1 |
Synonym | BDPLT14|CYP5|CYP5A1|GHOSAL|THAS|TS|TXAS|TXS;thromboxane A synthase 1 (platelet);TBXAS1;thromboxane A synthase 1 (platelet) |
Definition | TXA synthase|cytochrome P450 5A1|cytochrome P450, family 5, subfamily A, polypeptide 1|platelet, cytochrome P450, subfamily V|thromboxane-A synthase |
Position | 7q34-q35 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Eicosanoids;PID Reactome;500201 |
Pathway | Prostanoid metabolism;PID Reactome;500770 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | eicosanoid metabolism;PID BioCarta;100180 |
Pathway | aspirin blocks signaling pathway involved in platelet activation;PID BioCarta;100030 |
Pathway | Biological oxidations;Reactome;REACT:13433 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | prostanoid biosynthesis;BioCyc;PWY66-374 |
Pathway | Hormone biosynthesis;Reactome;REACT:15314 |
Pathway | Arachidonic acid metabolism;KEGG PATHWAY;hsa00590 |
Disease | Thromboxane synthase deficiency;OMIM |
Disease | CANCER;GAD |
Disease | Ghosal syndrome;OMIM |
Disease | ER positive;GAD |
External Links | |
Links to Entrez Gene | 6916 |
Links to all GeneRIF Items | 6916 |
Links to iHOP | 6916 |
Sequence Information | |
Nucleotide Sequence | >6916 : length: 2801 CTCTTTATAGGGAGACACTCTGAGAAAGAGCACATTGTGGGGGCCCACTCCATGTGATGT TTGCTTGGTTGCCTGTTCCCTTTTCTACCTGCAGAGCACGGTTCCCATAAGGGCGGCGAG ATCAGCCTCCTGTCTCATCTGGAAGACCACCACTCTGGGGTCTCAGAGGAATGATGGAAG CCTTGGGGTTTCTAAAATTGGAAGTGAATGGCCCCATGGTGACGGTGGCCCTGTCAGTGG CTCTCTTGGCCCTCCTGAAATGGTACTCCACATCAGCATTCTCAAGACTGGAGAAGTTAG GCCTCAGACATCCCAAGCCTTCTCCTTTCATTGGAAACTTGACATTTTTCCGCCAGGGTT TTTGGGAAAGCCAAATGGAGCTCAGAAAGCTGTATGGACCTCTGTGTGGGTACTATCTTG GTCGTCGGATGTTTATTGTTATTTCTGAGCCAGACATGATCAAGCAGGTGTTGGTTGAGA ACTTCAGTAACTTTACCAACAGAATGGCGTCGGGTTTGGAGTTCAAGTCGGTAGCCGACA GCGTTCTGTTTTTACGTGACAAAAGATGGGAAGAGGTCAGAGGTGCCCTGATGTCTGCTT TCAGTCCTGAAAAGCTGAACGAGATGGTTCCCCTCATCAGCCAAGCCTGCGACCTTCTCC TGGCTCATTTAAAACGCTATGCGGAATCTGGGGACGCATTTGACATCCAGAGGTGCTACT GCAATTACACCACAGATGTGGTTGCCAGCGTCGCCTTTGGCACCCCGGTGGACTCCTGGC AGGCCCCTGAGGATCCCTTTGTGAAACACTGCAAGCGTTTCTTCGAATTCTGCATCCCCA GACCTATCCTGGTTTTACTCTTATCATTTCCATCCATAATGGTCCCACTGGCCCGGATTT TGCCCAATAAGAACCGAGACGAACTGAATGGCTTTTTTAACAAACTCATTAGGAATGTGA TTGCCTTGCGGGACCAGCAAGCTGCCGAAGAGAGGCGGAGAGACTTCCTCCAAATGGTCC TGGATGCCCGACATTCTGCAAGTCCCATGGGCGTGCAAGACTTTGACATCGTCAGAGACG TTTTCTCCTCTACTGGGTGCAAGCCGAACCCTTCCCGGCAACACCAGCCCAGCCCTATGG CCAGGCCTTTGACTGTGGATGAGATTGTGGGCCAGGCCTTCATCTTCCTCATCGCTGGCT ATGAAATCATCACCAACACACTTTCTTTTGCCACCTACCTACTGGCCACCAACCCTGACT GCCAAGAGAAGCTTCTGAGAGAGGTAGACGTTTTTAAGGAGAAACACATGGCCCCTGAGT TCTGCAGCCTCGAGGAAGGCCTGCCCTATCTGGACATGGTGATTGCAGAGACGCTGAGGA TGTACCCGCCAGCTTTCAGATTCACACGGGAGGCAGCTCAGGACTGCGAGGTGCTGGGGC AGCGCATCCCCGCAGGCGCTGTGCTAGAGATGGCCGTGGGTGCCCTGCACCATGACCCTG AGCACTGGCCAAGCCCGGAGACCTTCAACCCTGAAAGGTCCAAACTGAATCCAGAGATTT AGCATTTCAGCAGCCCTGCATGCAAGGAACAAGGCAATTTCAAATGATTGTCTTCCATTC ATTCAAGCCAGGACATGGGATACAGGATTGTATTTCAGGTCTGCACTGGAAAGTAACGGA ACATCATTTCCTTTTTAAAAAACGGGCATCTATGCCAAAACAACAGCTTCAGCTGATGTC TCCATGAATCTAAATTCACGTGATCCACTGGTTGACCTGGGTCCCCGCCTTCCACCACCT GGCTTTGGTTCATTGTCTCCTTTCATTTCTGGGCTCTGTGATTGGAAACATCTGAGCAGG CGGCCCACACTCTGGTCCTCATCAGAACCAGTCAATATCCTGTGTGTGTGATCTGGCAAG GGAAGGGCTGGCCCGGCACCAGTTGTGTTTTCACCTTTCATGGCTCCAACTGAGTTCAGC CCAAGCCTACGACCCAGTCACTGGGAAAACGTGAGCAATGGGATCTACACAACAATATTC CACAGTCAGCAGCTCCTGAACGTGCCGCAGCCACAGGGCTTACAGCCTCACAATAAAGCC CAGGGGTAGTAAAAAGTGAGCTCGCTGTTACAGAACAGTGAGTGCCACCTAGCTTCACTG TCATGGGACACACGCTGCAGGCAAATGCACTACTTGGTAGGAGATTCAGCAGTTCTGAGG AAGGGCCTCCAGCTCTCCAGGTACTGCAGCTTCCAGTGGTTCAAGTGTCCAGTGCAGGGG CCTGCAAAGCAAACACGGGCAGGAGAGGGGCTGCCAGTGTGGCCCAAGAGACCTGCAGGG CAAGCCAGCAGGACACGCCCCCCAGGGAGGGCCCAGGAGGTGCTGAGGTGCCCGGTACCC TGCCAAGGAAGCAGGTGGCGGCTGGGTCATCCTATGGGAGGGGAGGTGGCGCCATGGGCC CAGGTGAGGGTGATCACCAAACCCTGGGGTTCAGGGATGCCGTGTTTAGACTCTGATTGT GGGTGGCGGTGAGTCTGTGGGCTTATTAGCCACACACTGAATTCCTAAGGAGAGGCAGGG AGGGAGCTGTGGACATTCCAGGTGATTCTGCGAATTCAGCTCTGCCTCTGGGGCTGTGCA GGAAGACAGGAGGCCAGGAGCAGAGAGGGACTGAGGCTCAGGAATGAGCAGCCATCAGCT CCCAGAGCCTTGGAGACATCCTTGTCTCAGATGCAGGGGTGGCTCAGCTGGAGCACAGGG CTGCAGAGGGGAGGGAGCGGGTGTTCTGGGCCAGCCCTGAC |
Protein Sequence | >6916 : length: 580 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS VADSVLFLRDKRWEEVRGALMSAFSPEKLNELGLLIMQERIKGHMGGQQAPQRIPPTRLS KPSGIYVNLHYATLPFCMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASV AFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNG FFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNP SRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDV FKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEM AVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTL LHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR |