| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6716 |
Name | SRD5A2 |
Synonym | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2);SRD5A2;steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
Definition | 3-oxo-5-alpha-steroid 4-dehydrogenase 2|5 alpha-SR2|S5AR 2|SR type 2|steroid 5-alpha-reductase 2|type II 5-alpha reductase |
Position | 2p23 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Steroid hormone biosynthesis;KEGG PATHWAY;hsa00140 |
Pathway | Hormone biosynthesis;Reactome;REACT:15314 |
Pathway | Prostate cancer;KEGG PATHWAY;hsa05215 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | androgen biosynthesis;BioCyc;PWY66-378 |
Disease | androgen;GAD |
Disease | micropenis;GAD |
Disease | DEVELOPMENTAL;GAD |
Disease | prostate cancer prostate specific antigen;GAD |
Disease | serum androgen concentrations;GAD |
Disease | breast cancer;GAD |
Disease | clinical parameters and endocrine status in elderly men;GAD |
Disease | prostate cancer;GAD |
Disease | CANCER;GAD |
Disease | METABOLIC;GAD |
Disease | hypospadias;GAD |
Disease | AGING;GAD |
Disease | Pseudovaginal perineoscrotal hypospadias;OMIM |
External Links | |
Links to Entrez Gene | 6716 |
Links to all GeneRIF Items | 6716 |
Links to iHOP | 6716 |
Sequence Information | |
Nucleotide Sequence | >6716 : length: 4909 GCTCAAACATTTAGGCAATAAAAGCTGATGGAAGCCAAAAAGCCACGCCACTGGCATCTG GTGTCAGGGTAGCTGCTGGGGGAGATCTGGCCATGGTGGTGGGGCCCAGCCATATAAACA AGTTCAGAGGTAGAACTGGAGCTGTGTACTGGGTTGAAGCATGTCTCTCCTAAATTCATG TTTTCTCTAGAACCTTAGACTATGACCTTATTTGGAAATAGGGTCTTTGCGATGTCATGC ATTGCTTAACATTGTGGTTACATTCTGAGTAATGTGTTGTTAGGTGATTTCATCATTGTC CAAACATCATAGAGTGTACTCACACAAACCTAGACGGTACAGTCTCCTACACACCTAGAC CATATACTATATCCTATTGTTCCTAGGCTGCAAACCTCTACAGCCTGTTACTGTACTGAC TACTGTAGGCAATTGGGGTACAATAATCTAATGAGACTATAATCATATATTTAGTGTGCC ATTGACCGAAATGTCATTATGATGCATGACTGTAGTTAAGATGAGGTCATACTGGATTAG GTAGGTTCTAAATCCAATGTGACTAGTGTCCTCATAAGAGGAGAGAAACAGACACAAACA CAGGGAAACACCGGGACGATGGCCATCTGAAGACAGAGGCAAACATTGGAGTGATGCAAT GACAAGCCAAGGAATGCCAAGGACTGCAAACCATTGCCAGAAGCTAGGAACACTCAAGAC ATTTGTGTACTCACTGCTCAATCGAGGGAGGCCTTATCCAGCTATACTCATTCTCAGAGG CACTGCCTTCTGCACTGGAAATGGAGTCCTTCAAGGCTACTATCTGATTTACTGTGCTGA ATACCCTGATGGGTGGTACACAGACATACGGTTTAGCTTGGGTGTCTTCTTATTTATTTT GGGAATGGGAATAAACATTCATAGTGACTATATATTGCGCCAGCTCAGGAAGCCTGGAGA AATCAGCTACAGGATTCCACAAGGTGGCTTGTTTACGTATGTTTCTGGAGCCAATTTCCT CGGTGAGATCATTGAATGGATCGGCTATGCCCTGGCCACTTGGTCCCTCCCAGCACTTGC ATTTGCATTTTTCTCACTTTGTTTCCTTGGGCTGCGAGCTTTTCACCACCATAGGTTCTA CCTCAAGATGTTTGAGGACTACCCCAAATCTCGGAAAGCCCTTATTCCATTCATCTTTTA AAGGAACCAAATTAAAAAGGAGCAGAGCTCCCACAATGCTGATGAAAACTGTCAAGCTGC TGAAACTGTAATTTTCATGATATAATAGTCCCGTATATATGTAATAGTAGGTCTCCTGGC GTTCTGCCAGCTGGCCTGGGGATTCTGAGTGGTGTCTGCTTAGAGTTTACTCCTACCCTT CCAGGGACCCCTATCCTGATCCCCAACTGAAGCTTCAAAAAGCCACTTTTCCAAATGGCG ACAGTTGCTTCTTAGCTATTGCTCTGAGAAAGTACAAACTTCTCCTATGTCTTTCACCGG GCAATCCAAGTACATGTGGCTTCATACCCACTCCCTGTCAATGCAGGACAACTCTGTAAT CAAGAATTTTTTGACTTGAAGGCAGTACTTATAGACCTTATTAAAGGTATGCATTTTATA CATGTAACAGAGTAGCAGAAATTTAAACTCTGAAGCCACAAAGACCCAGAGCAAACCCAC TCCCAAATGAAAACCCCAGTCATGGCTTCCTTTTTCTTGGTTAATTAGGAAAGATGAGAA ATTATTAGGTAGACCTTGAATACAGGAGCCCTCTCCTCATAGTGCTGAAAAGATACTGAT GCATTGACCTCATTTCAAATTTGTGCAGTGTCTTAGTTGATGAGTGCCTCTGTTTTCCAG AAGATTTCACAATCCCCGGAAAACTGGTATGGCTATTCTTGAAGGCCAGGTTTTAATAAC CACAAACAAAAAGGCATGAACCTGGGTGGCTTATGAGAGAGTAGAGAACAACATGACCCT GGATGGCTACTAAGAGGATAGAGAACAGTTTTACAATAGACATTGCAAACTCTCATGTTT TTGGAAACTAGTGGCAATATCCAAATAATGAGTAGTGTAAAACAAAGAGAATTAATGATG AGGTTACATGCTGCTTGCCTCCACCAGATGTCCACAACAATATGAAGTACAGCAGAAGCC CCAAGCAACTTTCCTTTCCTGGAGCTTCTTCCTTGTAGTTCTCAGGACCTGTTCAAGAAG GTGTCTCCTAGGGGCAGCCTGAATGCCTCCCTCAAAGGACCTGCAGGCAGAGACTGAAAA TTGCAGACAGAGGGGCACGTCTGGGCAGAAAACCTGTTTTGTTTGGCTCAGACATATAGT TTTTTTTTTTTTTACAAAGTTTCAAAAACTTAAAAATCAGGAGATTCCTTCATAAAACTC TAGCATTCTAGTTTCATTTAAAAAGTTGGAGGATCTGAACATACAGAGCCCACATTTCCA CACCAGAACTGGAACTACGTAGCTAGTAAGCATTTGAGTTTGCAAACTCTTGTGAAGGGG TCACCCCAGCATGAGTGCTGAGATATGGACTCTCTAAGGAAGGGGCCGAACGCTTGTAAT TGGAATACATGGAAATATTTGTCTTCTCAGGCCTATGTTTGCGGAATGCATTGTCAATAT TTAGCAAACTGTTTTGACAAATGAGCACCAGTGGTACTAAGCACAGAAACTCACTATATA AGTCACATAGGAAACTTGAAAGGTCTGAGGATGATGTAGATTACTGAAAAATGCAAATTG CAATCATATAAATAAGTGTTTTTGTTGTTCATTAAATACCTTTAAATCATGGATGTTAAG CAGTTTTGTTTGAATTAAAATATCCTGGGACTTCTGGAGATTTTCACAAGGTATTGGGGT GTGCTTCCCTGTCCCGCCTGTCCCTCATTCCCATTCACCCTGTCTGTAGTGTCGTTTCCT TTCTTCTCTTCTCTCTTCATGAAATTAGGGGCTGTGTGCTGGAAATAAAGAAGTATGACT TATACAGCCTCTCAGCCACAATTCAGAACTACAAGGAAGTACAATAAAGGTGCAGGAAAA CGTCATGAGGTTAGATGCCACTCCTGGTGCTGAGGAATACACAGGGGGAATGAACACACT TGGTGAAGTAAATCTTCAGGTGTAGCTTGAGCTCTGTGACATAAAAGACTTCCAGTTCTC TCCATGACATTGAAAACTACCTTGCTTAAGTCCTTTATTTTACTACCATGTAAAACATCC AGGCCGGTCCTTGAGATGAAATAAATATACAATAAATGGCAGTACTCAGTCTCAGGACAA AACCGCCATTTGGCAATTTCACTTTTTGCCACAAGAGGGCGCTTTCTAAAATAGTATTTA GTCCAACCTTGACTTAATTAGGTCCAACCCCAGTCCTGTTGCCTGATCGTGGACCTTTCA AGTTAGCATGATCGTGGAACTTCTTAATCTGAATATAGGGTAGAGTAGCGTGAACTCTAT GAAAGCTGAAACCTTCCCTTGATAATTCAGGTATTCTCAGTGTTCTAGGGCTGTTGTGTT CAATGACAGTTTGTCATTGTTTAGGGCTAGGATATGTATGTGGATTAAATACAGTAAAGG TCTGAACATGTGCTCATCTCTAAACATATTTCTTCCCACTTTTAAAAATAGGGTGCAACA AAATTATAGTTAATTGAGGTTTCCATGGACTGTTTTTTGGCTAAAATAATCTAACAGTGT CCTAGCTCACAAGATACTCTATCTTGGTCTTGCTGAAGCTTTCACGGAAGAGGCGTTTTC CTGCCAACCTTGAAGAAAATGTTGAGTTTTGTTTGTTTTTCAGAATTTAGACTTAAAGAG CTGAAGCAGACCTCAGACATCAGCTATTCCTACCACTTCACATTATAGGTAGTGACACTG AGACCCACAGAGTTAAAAGGCCTCCTCACAGCTGGTACAGAGCTGGTCAGAGCAGCCATC TCATTTTGTCCCTTTGAGGGTCAGATGTATGCTTCTTCTGCTTAAGGCACAGCCTTTAGG GCTGCCATCTGGATTTCTACAGAGCTCATGCAGGAGAAAAATAGCCAGAGCTTAAGTGCT GTTGCATAGTTCAGTTTATACACCTATTGTCCCATGCCTGTTTGTGTGTGAGGCTTCCCT CGCTCCGTGGGAGCACCAGGCTCATGCCCTTTCATAAACCTATTTGACAGAATAGAGAGT TTTCCCTCATTGGTGTAGTCAAGACAACATGTGTGTTCAGCATGGAAAAAAGGTTTCAGG TCATAAACCCCCTTATCCCTAATGCTTACTTTCATAAAGAACAACAGTGGCTCCACTGTA TTCTAAAAGGAAAAAGGAGCTCTAATGAGAAATACGCAATTAAACAGCTATTTAGGCGGC TTAGACCCTTTCAGGAACAAATAAATAAATCCGTGGTTTTACAACCCTGAAGTTTGATAA TAGCTCTCTTGGATTTTTGTGGTTACCTCATGGCAATCTCACTAAGAAGCAGGGGAGCAA GCTCTTGGCACATGAAGGAATAGGCTCATGAAGATTCATTTCTTTTCCCGCTTGGCCTTT TGGTTCTCTAATAAGCTGTGAGCTGAGGTCCATGCAGGGAAAACAAGGAGGGTAACGGCA AATGTAAAGTGAATTTTTCTGGAGAAGGATGCTGATTATTTTATAGCATCTACACTATCC TATGATGAAAGAGGCATAGAGCCGGGTGGCAATGTGAGTTCTTGGGTGATTTAATAAGCC ATCGAGTGGATTTAATTTCTAAGTAAGACATTTGTTTATTCTTTGTACAAGTCCATGGAG TTGTGATCTTAAAGAGTTCTGTGTTATTTGCATTGTGCCTCATTTCTCCCCATCAACCTT AGCTTGAGATTTGGATGAATAAAATAAATAACTGGAGAAGGTTAAAGTA |
Protein Sequence | >6716 : length: 254 MQVQCQQSPVLAGSATLVALGALALYVAKPSGYGKHTESLKPAATRLPARAAWFLQELPS FAVPAGILARQPLSLFGPPGTVLLGLFCLHYFHRTFVYSLLNRGRPYPAILILRGTAFCT GNGVLQGYYLIYCAEYPDGWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEISYRI PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE DYPKSRKALIPFIF |