| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6548 |
Name | SLC9A1 |
Synonym | APNH|LIKNS|NHE-1|NHE1|PPP1R143;solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1;SLC9A1;solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
Definition | Na(+)/H(+) exchanger 1|Na-Li countertransporter|protein phosphatase 1, regulatory subunit 143|sodium/hydrogen exchanger 1|solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive)|solute carrier family 9 (sod |
Position | 1p36.1-p35 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Pancreatic secretion;KEGG PATHWAY;hsa04972 |
Pathway | Endothelins;PID Curated;200004 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | RhoA signaling pathway;PID Curated;200007 |
Pathway | Signaling mediated by p38-alpha and p38-beta;PID Curated;200154 |
Pathway | Transmembrane transport of small molecules;Reactome;REACT:15518 |
Pathway | Salivary secretion;KEGG PATHWAY;hsa04970 |
Pathway | Cardiac muscle contraction;KEGG PATHWAY;hsa04260 |
Pathway | Gastric acid secretion;KEGG PATHWAY;hsa04971 |
Disease | Ischemia;FunDO |
Disease | diabetes, type 1;GAD |
Disease | IMMUNE;GAD |
Disease | Melanoma;FunDO |
Disease | Rabies;FunDO |
Disease | Breast cancer;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Cervical cancer;FunDO |
External Links | |
Links to Entrez Gene | 6548 |
Links to all GeneRIF Items | 6548 |
Links to iHOP | 6548 |
Sequence Information | |
Nucleotide Sequence | >6548 : length: 4757 GCTTCAGTCTGCTGCCGCCGGGGCCGGGGCTAGGGTTAGTTCTGGAGCTGGACCAGGAGG AGCTGCAGCTGGGCCGGGGCGGAGCGCCGCGTCGCGCCAGGGCCGCGAGGAGGGGCGTGT TGCTGCTGGCCCACCGCGAGCCGCCCCCAGCCCGCGCCGAGGCGCCTTCCCGCCAGGCCG CCTGCCTTCCGCCTCTTTCCATTTCCCCGGAATCTCAGCCCGGCGCGCCTGGACCCCTGC CCCTCTCTGGGTGGAGAAGCTCCCGGCCGCTTCCCGGTTTCACTCCTTCTCAGCCTGGGC TCCCAGCCCCCTCTCTCCTTTTCCTGGACTGGCTCTCACCCCCTTCGGTCCCCTTCCTTT AGCTCAGGCTCCCTACCCCTTCCTTTAGCCCACAGCCCAGAGTCCCAGCTCCTCAGTCAC TTTCCTCAGCCAAAGGTCCCAGCCTTCCTTCTTCCTTTCCTTTGCACTATCCCTATCCTG CCCCTTCCTCTATCCCTAGGGCTCAGTTTCCCACATCCGTCCTCCCCCTTCCCAGGCCCG GAGTTCCAGACCTTTTGGTCTCCTTTCGTGGTCGTTCCTGGGTCCTTGCCCCCTTTCCCC ACTTTGGAGTTCCAGATTGCAAACCCAGCCTCCCTCCACCCCCAGAAAATTGCTTCCATG GAAATGCCTCTCTAAAACATGAACTTTTCCTAGAGACTACGCCAGTCTCTCTTCCCACTT GCTGACCCTTTGCTACCTATGTGCCCGGTTTTACTCTCATTTGGGTAAGGTCGAGGCTGG CTCTGGAAGCAGCACCATGGTTCTGCGGTCTGGCATCTGTGGCCTCTCTCCACATCGGAT CTTCCCTTCCTTACTCGTGGTGGTTGCTTTGGTGGGGCTGCTGCCTGTTCTCAGGAGCCA TGGCCTCCAGCTCAGCCCAACTGCCAGCACCATTCGAAGCTCAGAGCCACCACGAGAACG CTCGATTGGGGATGTCACCACCGCTCCACCGGAGGTCACCCCAGAGAGCCGCCCTGTTAA TCATTCCGTCACTGATCATGGCATGAAGCCGCGCAAGGCCTTTCCAGTCCTGGGCATCGA CTACACACACGTGCGCACCCCCTTCGAGATCTCCCTCTGGATCCTTCTGGCCTGCCTCAT GAAGATAGGTTTCCATGTGATCCCCACTATCTCAAGCATCGTCCCGGAGAGCTGCCTGCT GATCGTGGTGGGGCTGCTGGTGGGGGGCCTGATCAAGGGTGTAGGCGAGACACCCCCCTT CCTGCAGTCCGACGTCTTCTTCCTCTTCCTGCTGCCGCCCATCATCCTGGATGCGGGCTA CTTCCTGCCACTGCGGCAGTTCACAGAAAACCTGGGCACCATCCTGATCTTTGCCGTGGT GGGCACGCTGTGGAACGCCTTCTTCCTGGGCGGCCTCATGTACGCCGTGTGCCTGGTGGG CGGTGAGCAGATCAACAACATCGGCCTCCTGGACAACCTGCTCTTCGGCAGCATCATCTC GGCCGTGGACCCCGTGGCGGTTCTGGCTGTCTTTGAGGAAATTCACATCAATGAGCTGCT GCACATCCTTGTTTTTGGGGAGTCCTTGCTCAATGACGCCGTCACTGTGGTCCTGTATCA CCTCTTTGAGGAGTTTGCCAACTACGAACACGTGGGCATCGTGGACATCTTCCTCGGCTT CCTGAGCTTCTTCGTGGTGGCCCTGGGCGGGGTGCTTGTGGGCGTGGTCTACGGGGTCAT CGCAGCCTTCACCTCCCGATTTACCTCCCACATCCGGGTCATCGAGCCGCTCTTCGTCTT CCTCTACAGCTACATGGCCTACTTGTCAGCCGAGCTCTTCCACCTGTCAGGCATCATGGC GCTCATAGCCTCAGGAGTGGTGATGCGCCCCTATGTGGAGGCCAACATCTCCCACAAGTC CCACACCACCATCAAATACTTCCTGAAGATGTGGAGCAGCGTCAGCGAGACCCTCATCTT CATCTTCCTCGGCGTCTCCACGGTGGCCGGCTCCCACCACTGGAACTGGACCTTCGTCAT CAGCACCCTGCTCTTCTGCCTCATCGCCCGCGTGCTGGGGGTGCTGGGCCTGACCTGGTT CATCAACAAGTTCCGTATCGTGAAGCTGACCCCCAAGGACCAGTTCATCATCGCCTATGG GGGCCTGCGAGGGGCCATCGCCTTCTCTCTGGGCTACCTCCTGGACAAGAAGCACTTCCC CATGTGTGACCTGTTCCTCACTGCCATCATCACTGTCATCTTCTTCACCGTCTTTGTGCA GGGCATGACCATTCGGCCCCTGGTAGACCTGTTGGCTGTGAAGAAAAAGCAAGAGACGAA GCGCTCCATCAACGAAGAGATCCACACACAGTTCCTGGACCACCTTCTGACAGGCATCGA AGACATCTGTGGCCACTACGGTCACCACCACTGGAAGGACAAGCTCAACCGGTTTAATAA GAAATATGTGAAGAAGTGTCTGATAGCTGGCGAGCGCTCCAAGGAGCCCCAGCTCATTGC CTTCTACCACAAGATGGAGATGAAGCAGGCCATCGAGCTGGTGGAGAGCGGGGGCATGGG CAAGATCCCCTCTGCCGTCTCCACCGTCTCCATGCAGAACATCCACCCCAAGTCCCTGCC TTCCGAGCGCATCCTGCCAGCACTGTCCAAGGACAAGGAGGAGGAGATCCGCAAAATCCT GAGGAACAACTTGCAGAAGACCAGGCAGCGGCTGCGGTCCTACAACAGACACACGCTGGT GGCAGACCCCTACGAGGAAGCCTGGAACCAGATGCTGCTCCGGAGGCAGAAGGCCCGGCA GCTGGAGCAGAAGATCAACAACTACCTGACGGTGCCAGCCCACAAGCTGGACTCACCCAC CATGTCTCGGGCCCGCATCGGCTCAGACCCACTGGCCTATGAGCCGAAGGAGGACCTGCC TGTCATCACCATCGACCCGGCTTCCCCGCAGTCACCCGAGTCTGTGGACCTGGTGAATGA AGAGCTGAAGGGCAAAGTCTTAGGGTTGAGCCGGGATCCTGCAAAGGTGGCTGAGGAGGA CGAGGACGACGATGGGGGCATCATGATGCGGAGCAAGGAGACTTCGTCCCCAGGAACCGA CGATGTCTTCACCCCCGCGCCCAGTGACAGCCCCAGCTCCCAGAGGATACAGCGCTGCCT CAGTGACCCAGGCCCACACCCTGAGCCTGGGGAGGGAGAACCGTTCTTCCCCAAGGGGCA GTAACACCAGGGCCAGCAGGCAGCGCCTGTCCCCTCACAGACTCTTCCACCAGAGCAGGG GCTGCTGGGGGCTCCCCTTGCCCTTCCTGACCCGGATTGGCCCTGCCCCTCCCCCTACCG CATGGCAGCTGGGCCCACAGCCCCCACCCCAGCACAGCTCCTCCCCTGCCGCCTCCCGGG AAGCATCCTCCCCACCAGAGCTGCCTCCCCAATCCATTTGGCAGAACTGCTGGGGCTGGT GAGGCCGGCCCTGCCCCTCCCTAGATCCAGGCTTCTCCCGGACCTGGACTAGGGCCTCGG AGGCTCCTCCCTCTGCCTCATCCTCCTCCTCATTCAGACCAATCTTAGTTTCTAACCAAA GAGTCTCTGGCTCAGCTGTGGTCCCACCCAGGAAGGGAGGGAGCTGAGGCCTCCCTTGAG TAGGCCCTGCTTTATCAGGGGACAAACCAGGGGTACCAGGCACATGGCTGGGGGAGGGAC TGCTGACCCACCAAGGTCTCACACTCCTCCTGCCAGCTCTGTCACCCTGGCCACCACCCA ACCTGTCCTTACTCAGAGCTGCGGGCTGAGGGCATCTCTGAGTGTCTCTGCCTGGAGCAG GGGTGGTTTCTACGGTGACAGTGACGTGACTCAGAGCTTTTCGAACTGTGCTCCCACGGG GACCACTGGGCCCCTCAGGGGAAGCTGCTAGGGGAAGGACTGGCCGTGGCTCCAGAATGT GCTGCCTTTTTAAGTTTTGTTTGTTCACACTCCTATATATGATTGTTTGCACAGAGGGCG CTCCTGTTTTTAAAACATTTTGAAAACCCCTGGCTGAACAGTGCTCTGCCTCTAACTCCC TCCTCACACTCCAGAATTACCCTTCCTCATCTGTGCCTGTCTGTCCAACCCCTCCCCCAC GTCTCTCTGCCTGCTGGGCTCTTAACTGTTGCTCGAAGACTGTGACATCAGAAGTAACTC CCACTCCTAATCAAGAGTCTCTCCAGCCTCACAGATGCTGGCCTCTTGGCACCTGCCTAG CTCTTGGGCCTGACCTCCAGTCCTGCTGGCCTGCTCTTACTTCCCCCACCCTGGGTTTGG CCCCTGGAACCTTTCCCTTGTGTGTACCACACCCTGCCTGCTGTGGAGCCCATTGTGGAG GCGGTGGGGGGGAGAAGGCCTCCCCTGAGGATCCCCTGTCCCCTGGGGCTGGTGGATTGG GCAGAATCCTGGGCCCCCAGAGACCTTTGCCCACACACACTCCTTCCCCTTGTCCCTGGG GCACTCCCCCAGGATTGTGCAATAGTCAGAGTGTCCCTTTTTGCAGGGGACTGGGCCATG GGTCCTCGGCCCATCTGTCCATCCTCCTCTCCATGCAAGTGCTGTTTGGGCAGGAGTCAC CATGCAAGGGTGACATCGACAACCACGTACCAAGCCACCGCAGCTGCTGCCACTCTGCTG CCTGTACAGAAGAAACTGAATCTTTTTCATATTCTAATAAATCAATGTGAGTTTTTAATA GAAAAAAAAAAAAAAAA |
Protein Sequence | >6548 : length: 815 MVLRSGICGLSPHRIFPSLLVVVALVGLLPVLRSHGLQLSPTASTIRSSEPPRERSIGDV TTAPPEVTPESRPVNHSVTDHGMKPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFH VIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLR QFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPV AVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFFV VALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASG VVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLF CLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLF LTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGH YGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSA VSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYE EAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITID PASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTP APSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ |