| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6494 |
Name | SIPA1 |
Synonym | SPA1;signal-induced proliferation-associated 1;SIPA1;signal-induced proliferation-associated 1 |
Definition | GTPase-activating protein Spa-1|p130 SPA-1|signal-induced proliferation-associated gene 1|signal-induced proliferation-associated protein 1|sipa-1 |
Position | 11q13 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670 |
Disease | Breast cancer;FunDO |
Disease | breast cancer;GAD |
Disease | CANCER;GAD |
Disease | Metastasis efficiency, modification of;OMIM |
External Links | |
Links to Entrez Gene | 6494 |
Links to all GeneRIF Items | 6494 |
Links to iHOP | 6494 |
Sequence Information | |
Nucleotide Sequence | >6494 : length: 3642 GGCAGGGTGACTGGGGTCCCATGACAGCTGCTGTGACCCCAGCACCTTCCTCAGGATGTG GGGGCCTGGCAGAGGGCTGGGCCCACAGTTGGGGCTACTTCCTGTGCTGAAGGAAGTCCT CTTGCCATTCCTGCTGCCCTGCCGCTGCCTCCCTGGGAACCCATGTGTCCTTGTGGCCCC TCTGAGCAGCCCCCTCCTCCTTCAGGGCAGGAACTGCTGCCACAACCTCAGGCTGGGCAC CAAACACCCGTGCCCGCCAATGCGGCCCAGCCCCCGGAGAGTCAGGCCCACAGAGCATGC CCATGTGGGCCGGCGGTGTGGGGAGCCCTCGGCGGGGCATGGCCCCTGCGTCCACAGATG ACCTCTTTGCCCGCAAGCTGCGCCAGCCAGCAAGGCCCCCGCTGACACCGCACACCTTCG AGCCGAGGCCAGTCCGGGGCCCACTCCTGCGCAGCGGCAGCGATGCAGGCGAGGCCAGGC CCCCCACGCCAGCCAGCCCCCGTGCCCGTGCCCACAGCCACGAAGAGGCCAGCCGACCTG CAGCCACTTCCACCCGGCTCTTCACTGACCCGCTGGCACTGCTGGGGCTGCCAGCAGAGG AACCAGAGCCTGCCTTCCCACCAGTGCTTGAGCCTCGATGGTTTGCCCACTATGACGTGC AAAGCCTGCTCTTTGATTGGGCTCCGAGGTCTCAGGGGATGGGGAGCCACTCAGAGGCCA GCTCTGGGACCCTGGCTTCAGCCGAGGACCAGGCTGCCAGCTCGGACCTGCTGCATGGGG CACCTGGCTTTGTGTGTGAGCTCGGGGGTGAGGGTGAGCTAGGCCTGGGTGGACCAGCAT CCCCACCTGTGCCCCCTGCACTGCCCAACGCGGCCGTGTCCATCCTGGAGGAGCCACAGA ACCGAACCTCGGCCTACAGCCTGGAGCACGCAGACCTGGGTGCTGGCTACTACCGCAAAT ACTTCTATGGCAAAGAACATCAGAACTTCTTCGGGATGGACGAGTCGCTGGGCCCGGTGG CAGTGAGCCTGCGGCGGGAGGAGAAGGAGGGCAGCGGAGGGGGCACCCTGCACAGCTACC GCGTCATCGTGCGGACCACGCAGCTCCGGACACTCCGTGGCACCATCTCGGAGGACGCGC TGCCGCCGGGGCCCCCACGGGGTCTGTCCCCAAGGAAACTTCTGGAGCACGTGGCGCCGC AGCTGAGCCCCAGCTGCCTGCGCCTGGGCTCAGCTTCACCCAAGGTACCACGGACGCTGC TCACACTGGATGAGCAAGTGCTGAGCTTCCAACGCAAGGTGGGCATCCTGTACTGCCGGG CGGGCCAGGGCTCGGAGGAGGAGATGTACAACAACCAGGAGGCGGGACCGGCCTTCATGC AGTTTCTCACCTTGCTGGGCGATGTGGTGCGGCTCAAAGGCTTTGAGAGTTACCGGGCCC AGCTAGACACCAAAACGGATTCCACAGGCACGCACTCCCTCTACACCACATACCAGGACC ACGAGATCATGTTCCACGTGTCCACGATGCTGCCTTACACCCCTAATAACCAGCAGCAGC TCCTCCGGAAGCGCCACATTGGCAACGACATTGTGACCATCGTGTTCCAGGAGCCTGGCA GCAAGCCCTTCTGCCCCACCACCATCCGCTCGCACTTCCAGCACGTGTTCCTAGTGGTGC GGGCACACACACCCTGCACGCCACACACCACCTACAGGGTGGCCGTGAGCCGCACCCAGG ACACCCCTGCCTTCGGGCCAGCTCTGCCTGCTGGCGGAGGCCCCTTCGCAGCCAACGCCG ACTTCCGGGCCTTCCTGCTGGCCAAAGCGCTGAATGGTGAGCAGGCGGCCGGCCACGCGC GCCAGTTCCACGCCATGGCCACGCGCACCCGCCAGCAGTACCTGCAAGACCTGGCCACCA ACGAGGTGACCACTACGTCGCTGGACTCGGCTTCACGCTTCGGCCTGCCCTCCCTGGGTG GGAGGCGCCGGGCGGCCCCTCGGGGCCCAGGCGCCGAGCTGCAGGCAGCGGGCTCACTGG TGTGGGGAGTGCGCGCGGCGCCCGGGGCGCGGGTCGCCGCCGGGGCTCAGGCGAGCGGCC CCGAAGGCATCGAGGTGCCCTGCCTGCTGGGCATCTCGGCCGAGGCTCTGGTGCTGGTGG CGCCGCGCGACGGCCGCGTAGTGTTCAATTGCGCCTGTCGCGACGTGCTGGCCTGGACCT TCTCCGAGCAGCAGCTGGACCTGTACCACGGCCGCGGGGAGGCGATCACGCTGCGCTTCG ACGGGTCCCCCGGCCAAGCCGTGGGCGAGGTGGTGGCGCGCCTGCAGCTGGTGAGCCGTG GCTGCGAGACCCGCGAGCTGGCGCTGCCCCGCGACGGTCAAGGCCGCCTGGGCTTCGAGG TGGACGCCGAGGGATTCGTCACGCACGTGGAGCGCTTCACATTCGCCGAGACGGCGGGGC TGCGGCCCGGGGCGCGCCTCCTGCGCGTGTGCGGCCAGACGCTGCCCAGCCTCCGGCCCG AGGCCGCTGCCCAGCTCCTGCGCTCGGCGCCCAAGGTCTGCGTCACCGTCCTGCCCCCCG ACGAGAGCGGCCGGCCCCGCAGGAGTTTTTCGGAGCTGTACACGCTGTCGCTGCAGGAGC CTAGCCGGCGGGGGGCCCCAGATCCTGTGCAGGATGAGGTCCAGGGGGTGACCCTGCTGC CCACCACAAAGCAGCTGCTGCACCTGTGCCTGCAAGATGGTGGCAGTCCTCCAGGGCCTG GGGATCTGGCCGAGGAGAGGACTGAGTTCCTGCACAGCCAGAACTCGCTGTCACCACGCA GCTCTCTGTCGGATGAGGCCCCAGTCCTGCCCAACACCACCCCGGACCTCCTCCTGGCCA CCACAGCCAAGCCATCAGTACCCAGTGCTGACAGTGAGACACCCCTGACCCAGGACAGGC CAGGCAGTCCCAGTGGCTCTGAGGACAAGGGCAACCCGGCGCCGGAGCTGAGGGCCTCCT TTCTGCCACGTACCTTGTCTCTGCGGAACTCCATCAGCAGGATCATGTCGGAGGCGGGCA GTGGGACCCTGGAGGACGAGTGGCAGGCCATCTCGGAGATTGCCTCTACTTGCAACACCA TTCTGGAGTCGCTGTCCCGAGAGGGACAGCCCATCCCAGAGAGTGGAGACCCTAAGGGAA CTCCAAAATCTGATGCTGAGCCAGAGCCTGGGAACCTCTCAGAGAAGGTCTCTCACTTGG AGTCCATGCTCAGGAAGCTGCAGGAGGACCTGCAGAAGGAGAAGGCGGACAGGGCGGCCC TGGAGGAGGAGGTGCGGAGCCTGAGACACAACAACCGGCGGCTGCAGGCGGAGTCTGAGA GTGCAGCCACACGCCTCCTCCTGGCCTCCAAGCAGCTGGGCTCACCCACCGCCGACCTGG CCTGAGCCGTCTGGAACCACCTGGGCCCCTGAGGGCACTGTGGTCACACTGGGCCCTCCT CAGGAACTCTCCCTGCGCAGAGGCGTGTCTTAGCACTGCCCCCCTCCCTAGCCCCTTATT TGGTGGCGGAAGTGGCCTCCACCCCTTCCCTGTTTGTAAATATTCTGTGGAGAAAAGAGG ACTTCAGGGAGTAAAAAAGCCACTGATGTCAAAAAAAAAAAA |
Protein Sequence | >6494 : length: 1042 MPMWAGGVGSPRRGMAPASTDDLFARKLRQPARPPLTPHTFEPRPVRGPLLRSGSDAGEA RPPTPASPRARAHSHEEASRPAATSTRLFTDPLALLGLPAEEPEPAFPPVLEPRWFAHYD VQSLLFDWAPRSQGMGSHSEASSGTLASAEDQAASSDLLHGAPGFVCELGGEGELGLGGP ASPPVPPALPNAAVSILEEPQNRTSAYSLEHADLGAGYYRKYFYGKEHQNFFGMDESLGP VAVSLRREEKEGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVA PQLSPSCLRLGSASPKVPRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAF MQFLTLLGDVVRLKGFESYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQ QLLRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRT QDTPAFGPALPAGGGPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLA TNEVTTTSLDSASRFGLPSLGGRRRAAPRGPGAELQAAGSLVWGVRAAPGARVAAGAQAS GPEGIEVPCLLGISAEALVLVAPRDGRVVFNCACRDVLAWTFSEQQLDLYHGRGEAITLR FDGSPGQAVGEVVARLQLVSRGCETRELALPRDGQGRLGFEVDAEGFVTHVERFTFAETA GLRPGARLLRVCGQTLPSLRPEAAAQLLRSAPKVCVTVLPPDESGRPRRSFSELYTLSLQ EPSRRGAPDPVQDEVQGVTLLPTTKQLLHLCLQDGGSPPGPGDLAEERTEFLHSQNSLSP RSSLSDEAPVLPNTTPDLLLATTAKPSVPSADSETPLTQDRPGSPSGSEDKGNPAPELRA SFLPRTLSLRNSISRIMSEAGSGTLEDEWQAISEIASTCNTILESLSREGQPIPESGDPK GTPKSDAEPEPGNLSEKVSHLESMLRKLQEDLQKEKADRAALEEEVRSLRHNNRRLQAES ESAATRLLLASKQLGSPTADLA |