| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 64127 |
Name | NOD2 |
Synonym | ACUG|BLAU|CARD15|CD|CLR16.3|IBD1|NLRC2|NOD2B|PSORAS1;nucleotide-binding oligomerization domain containing 2;NOD2;nucleotide-binding oligomerization domain containing 2 |
Definition | NLR family, CARD domain containing 2|NOD-like receptor C2|caspase recruitment domain family, member 15|caspase recruitment domain protein 15|caspase recruitment domain-containing protein 15|inflammatory bowel disease protein 1|nucleotide-binding oligomeri |
Position | 16q21 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Canonical NF-kappaB pathway;PID Curated;200026 |
Pathway | NOD-like receptor signaling pathway;KEGG PATHWAY;hsa04621 |
Pathway | Shigellosis;KEGG PATHWAY;hsa05131 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Disease | inflammatory bowel disease;GAD |
Disease | Mycobacterium infection, Atypical;FunDO |
Disease | Sarcoidosis, early-onset;OMIM |
Disease | Lung cancer;FunDO |
Disease | Periodontitis;FunDO |
Disease | Psoriasis;FunDO |
Disease | Psoriatic arthritis, susceptibility to;OMIM |
Disease | Lung disease;FunDO |
Disease | Breast cancer;FunDO |
Disease | Ulcerative colitis;FunDO |
Disease | Crohn's disease ulcerative colitis;GAD |
Disease | Dermatitis;FunDO |
Disease | graft-versus-host disease;GAD |
Disease | Inflammatory bowel disease;NHGRI |
Disease | IMMUNE;GAD |
Disease | Rheumatoid arthritis;FunDO |
Disease | Leprosy;GAD |
Disease | Leukemia;FunDO |
Disease | Systemic infection;FunDO |
Disease | Sarcoidosis;FunDO |
Disease | Stomach Diseases;GAD |
Disease | INFECTION;GAD |
Disease | Colon cancer;FunDO |
Disease | psoriatic arthritis;GAD |
Disease | colorectal cancer;GAD |
Disease | Pre-Eclampsia;FunDO |
Disease | Tuberculosis;FunDO |
Disease | Bronchiolitis obliterans;FunDO |
Disease | Crohn Disease;GAD |
Disease | Multiple sclerosis;FunDO |
Disease | Blau syndrome;KEGG DISEASE;H00285 |
Disease | CANCER;GAD |
Disease | allergies;GAD |
Disease | Crohn's disease;GAD |
Disease | Blau syndrome;OMIM |
Disease | Crohn's disease;NHGRI |
Disease | Crohn disease, susceptibility to;OMIM |
Disease | Crohn's disease;KEGG DISEASE;H00286 |
Disease | Behcet syndrome;FunDO |
Disease | Abortion;FunDO |
Disease | Asthma;GAD |
Disease | Immune system diseases;KEGG DISEASE |
Disease | sarcoidosis;GAD |
Disease | neonatal sepsis;GAD |
Disease | Other immune system disease;KEGG DISEASE |
Disease | Congenital abnormality;FunDO |
Disease | Leprosy;NHGRI |
Disease | Spondylarthropathies;FunDO |
Disease | Duodenal Diseases;GAD |
Disease | ulcerative colitis;GAD |
Disease | Uveitis;FunDO |
Disease | Enteritis;FunDO |
Disease | Arthritis;FunDO |
External Links | |
Links to Entrez Gene | 64127 |
Links to all GeneRIF Items | 64127 |
Links to iHOP | 64127 |
Sequence Information | |
Nucleotide Sequence | >64127 : length: 4499 GTAGACAGATCCAGGCTCACCAGTCCTGTGCCACTGGGCTTTTGGCGTTCTGCACAAGGC CTACCCGCAGATGCCATGCCTGCTCCCCCAGCCTAATGGGCTTTGATGGGGGAAGAGGGT GGTTCAGCCTCTCACGATGAGGAGGAAAGAGCAAGTGTCCTCCTCGGACATTCTCCGGGT TGTGAAATGTGCTCGCAGGAGGCTTTTCAGGCACAGAGGAGCCAGCTGGTCGAGCTGCTG GTCTCAGGGTCCCTGGAAGGCTTCGAGAGTGTCCTGGACTGGCTGCTGTCCTGGGAGGTC CTCTCCTGGGAGGACTACGAGGGCTTCCACCTCCTGGGCCAGCCTCTCTCCCACTTGGCC AGGCGCCTTCTGGACACCGTCTGGAATAAGGGTACTTGGGCCTGTCAGAAGCTCATCGCG GCTGCCCAAGAAGCCCAGGCCGACAGCCAGTCCCCCAAGCTGCATGGCTGCTGGGACCCC CACTCGCTCCACCCAGCCCGAGACCTGCAGAGTCACCGGCCAGCCATTGTCAGGAGGCTC CACAGCCATGTGGAGAACATGCTGGACCTGGCATGGGAGCGGGGTTTCGTCAGCCAGTAT GAATGTGATGAAATCAGGTTGCCGATCTTCACACCGTCCCAGAGGGCAAGAAGGCTGCTT GATCTTGCCACGGTGAAAGCGAATGGATTGGCTGCCTTCCTTCTACAACATGTTCAGGAA TTACCAGTCCCATTGGCCCTGCCTTTGGAAGCTGCCACATGCAAGAAGTATATGGCCAAG CTGAGGACCACGGTGTCTGCTCAGTCTCGCTTCCTCAGTACCTATGATGGAGCAGAGACG CTCTGCCTGGAGGACATATACACAGAGAATGTCCTGGAGGTCTGGGCAGATGTGGGCATG GCTGGACCCCCGCAGAAGAGCCCAGCCACCCTGGGCCTGGAGGAGCTCTTCAGCACCCCT GGCCACCTCAATGACGATGCGGACACTGTGCTGGTGGTGGGTGAGGCGGGCAGTGGCAAG AGCACGCTCCTGCAGCGGCTGCACTTGCTGTGGGCTGCAGGGCAAGACTTCCAGGAATTT CTCTTTGTCTTCCCATTCAGCTGCCGGCAGCTGCAGTGCATGGCCAAACCACTCTCTGTG CGGACTCTACTCTTTGAGCACTGCTGTTGGCCTGATGTTGGTCAAGAAGACATCTTCCAG TTACTCCTTGACCACCCTGACCGTGTCCTGTTAACCTTTGATGGCTTTGACGAGTTCAAG TTCAGGTTCACGGATCGTGAACGCCACTGCTCCCCGACCGACCCCACCTCTGTCCAGACC CTGCTCTTCAACCTTCTGCAGGGCAACCTGCTGAAGAATGCCCGCAAGGTGGTGACCAGC CGTCCGGCCGCTGTGTCGGCGTTCCTCAGGAAGTACATCCGCACCGAGTTCAACCTCAAG GGCTTCTCTGAACAGGGCATCGAGCTGTACCTGAGGAAGCGCCATCATGAGCCCGGGGTG GCGGACCGCCTCATCCGCCTGCTCCAAGAGACCTCAGCCCTGCACGGTTTGTGCCACCTG CCTGTCTTCTCATGGATGGTGTCCAAATGCCACCAGGAACTGTTGCTGCAGGAGGGGGGG TCCCCAAAGACCACTACAGATATGTACCTGCTGATTCTGCAGCATTTTCTGCTGCATGCC ACCCCCCCAGACTCAGCTTCCCAAGGTCTGGGACCCAGTCTTCTTCGGGGCCGCCTCCCC ACCCTCCTGCACCTGGGCAGACTGGCTCTGTGGGGCCTGGGCATGTGCTGCTACGTGTTC TCAGCCCAGCAGCTCCAGGCAGCACAGGTCAGCCCTGATGACATTTCTCTTGGCTTCCTG GTGCGTGCCAAAGGTGTCGTGCCAGGGAGTACGGCGCCCCTGGAATTCCTTCACATCACT TTCCAGTGCTTCTTTGCCGCGTTCTACCTGGCACTCAGTGCTGATGTGCCACCAGCTTTG CTCAGACACCTCTTCAATTGTGGCAGGCCAGGCAACTCACCAATGGCCAGGCTCCTGCCC ACGATGTGCATCCAGGCCTCGGAGGGAAAGGACAGCAGCGTGGCAGCTTTGCTGCAGAAG GCCGAGCCGCACAACCTTCAGATCACAGCAGCCTTCCTGGCAGGGCTGTTGTCCCGGGAG CACTGGGGCCTGCTGGCTGAGTGCCAGACATCTGAGAAGGCCCTGCTCCGGCGCCAGGCC TGTGCCCGCTGGTGTCTGGCCCGCAGCCTCCGCAAGCACTTCCACTCCATCCCGCCAGCT GCACCGGGTGAGGCCAAGAGCGTGCATGCCATGCCCGGGTTCATCTGGCTCATCCGGAGC CTGTACGAGATGCAGGAGGAGCGGCTGGCTCGGAAGGCTGCACGTGGCCTGAATGTTGGG CACCTCAAGTTGACATTTTGCAGTGTGGGCCCCACTGAGTGTGCTGCCCTGGCCTTTGTG CTGCAGCACCTCCGGCGGCCCGTGGCCCTGCAGCTGGACTACAACTCTGTGGGTGACATT GGCGTGGAGCAGCTGCTGCCTTGCCTTGGTGTCTGCAAGGCTCTGTATTTGCGCGATAAC AATATCTCAGACCGAGGCATCTGCAAGCTCATTGAATGTGCTCTTCACTGCGAGCAATTG CAGAAGTTAGCTCTATTCAACAACAAATTGACTGACGGCTGTGCACACTCCATGGCTAAG CTCCTTGCATGCAGGCAGAACTTCTTGGCATTGAGGCTGGGGAATAACTACATCACTGCC GCGGGAGCCCAAGTGCTGGCCGAGGGGCTCCGAGGCAACACCTCCTTGCAGTTCCTGGGA TTCTGGGGCAACAGAGTGGGTGACGAGGGGGCCCAGGCCCTGGCTGAAGCCTTGGGTGAT CACCAGAGCTTGAGGTGGCTCAGCCTGGTGGGGAACAACATTGGCAGTGTGGGTGCCCAA GCCTTGGCACTGATGCTGGCAAAGAACGTCATGCTAGAAGAACTCTGCCTGGAGGAGAAC CATCTCCAGGATGAAGGTGTATGTTCTCTCGCAGAAGGACTGAAGAAAAATTCAAGTTTG AAAATCCTGAAGTTGTCCAATAACTGCATCACCTACCTAGGGGCAGAAGCCCTCCTGCAG GCCCTTGAAAGGAATGACACCATCCTGGAAGTCTGGCTCCGAGGGAACACTTTCTCTCTA GAGGAGGTTGACAAGCTCGGCTGCAGGGACACCAGACTCTTGCTTTGAAGTCTCCGGGAG GATGTTCGTCTCAGTTTGTTTGTGAGCAGGCTGTGAGTTTGGGCCCCAGAGGCTGGGTGA CATGTGTTGGCAGCCTCTTCAAAATGAGCCCTGTCCTGCCTAAGGCTGAACTTGTTTTCT GGGAACACCATAGGTCACCTTTATTCTGGCAGAGGAGGGAGCATCAGTGCCCTCCAGGAT AGACTTTTCCCAAGCCTACTTTTGCCATTGACTTCTTCCCAAGATTCAATCCCAGGATGT ACAAGGACAGCCCCTCCTCCATAGTATGGGACTGGCCTCTGCTGATCCTCCCAGGCTTCC GTGTGGGTCAGTGGGGCCCATGGATGTGCTTGTTAACTGAGTGCCTTTTGGTGGAGAGGC CCGGCCTCTCACAAAAGACCCCTTACCACTGCTCTGATGAAGAGGAGTACACAGAACACA TAATTCAGGAAGCAGCTTTCCCCATGTCTCGACTCATCCATCCAGGCCATTCCCCGTCTC TGGTTCCTCCCCTCCTCCTGGACTCCTGCACACGCTCCTTCCTCTGAGGCTGAAATTCAG AATATTAGTGACCTCAGCTTTGATATTTCACTTACAGCACCCCCAACCCTGGCACCCAGG GTGGGAAGGGCTACACCTTAGCCTGCCCTCCTTTCCGGTGTTTAAGACATTTTTGGAAGG GGACACGTGACAGCCGTTTGTTCCCCAAGACATTCTAGGTTTGCAAGAAAAATATGACCA CACTCCAGCTGGGATCACATGTGGACTTTTATTTCCAGTGAAATCAGTTACTCTTCAGTT AAGCCTTTGGAAACAGCTCGACTTTAAAAAGCTCCAAATGCAGCTTTAAAAAATTAATCT GGGCCAGAATTTCAAACGGCCTCACTAGGCTTCTGGTTGATGCCTGTGAACTGAACTCTG ACAACAGACTTCTGAAATAGACCCACAAGAGGCAGTTCCATTTCATTTGTGCCAGAATGC TTTAGGATGTACAGTTATGGATTGAAAGTTTACAGGAAAAAAAATTAGGCCGTTCCTTCA AAGCAAATGTCTTCCTGGATTATTCAAAATGATGTATGTTGAAGCCTTTGTAAATTGTCA GATGCTGTGCAAATGTTATTATTTTAAACATTATGATGTGTGAAAACTGGTTAATATTTA TAGGTCACTTTGTTTTACTGTCTTAAGTTTATACTCTTATAGACAACATGGCCGTGAACT TTATGCTGTAAATAATCAGAGGGGAATAAACTGTTGAGTCAAAACAAAAAAAAAAAAAA |
Protein Sequence | >64127 : length: 1040 MGEEGGSASHDEEERASVLLGHSPGCEMCSQEAFQAQRSQLVELLVSGSLEGFESVLDWL LSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLH GCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQR ARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTY DGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGE AGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQ EDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNAR KVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALH GLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLL RGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLE FLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVA ALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFH SIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECA ALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECAL HCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTS LQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEEL CLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRG NTFSLEEVDKLGCRDTRLLL |