| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6091 |
Name | ROBO1 |
Synonym | DUTT1|SAX3;roundabout, axon guidance receptor, homolog 1 (Drosophila);ROBO1;roundabout, axon guidance receptor, homolog 1 (Drosophila) |
Definition | deleted in U twenty twenty|roundabout homolog 1 |
Position | 3p12 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Inactivation of Cdc42 and Rac;PID Reactome;500094 |
Pathway | Role of Abl in Robo-Slit signaling;PID Reactome;500096 |
Pathway | Axon guidance mediated by Slit/Robo;PANTHER;P00008 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Activation of Rac;PID Reactome;500095 |
Pathway | Netrin-1 signaling;PID Reactome;500088 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Signaling by Robo receptor;PID Reactome;500092 |
Disease | PSYCH;GAD |
Disease | protein quantitative trait loci;GAD |
Disease | Brain imaging in schizophrenia (interaction);GAD |
Disease | Cancer;FunDO |
Disease | Protein quantitative trait loci;NHGRI |
External Links | |
Links to Entrez Gene | 6091 |
Links to all GeneRIF Items | 6091 |
Links to iHOP | 6091 |
Sequence Information | |
Nucleotide Sequence | >6091 : length: 7550 AATTGAGCTGGAGAGGAGGCAGCGTGAGAGCAGAAACTTCAGACGCCGCTGATCCGGGAG GAGCTGGGGTGAGCCGCGGCGGCCGTCTCTCCCACCCGCAGCAGCATCCTCTCTGCCCTT CTCTGCCACCCCGGGGAGAGCCGGGAGCTGCCTCTTTACAGCTTCCACGAGCCAGGGGTG CAGGCAGCTGCCCCCAGGAAGTTTGGGCTTCTGCGTAGTTTAGGGGTGCCTGCGAGCGCC CCAGAGGGCGAGGGGCCGAGGGCGATGTTGGGCGCCGCGCGGGGCTGGGGGCGCCCAGAA GACGTGCGAGTGTCCGCGGTCCTGCTGCTGTCTCCAGTACCCTCCGCATCCCCCAAGTGA TGGGAACAAGGGCCCGCCCAGGCAGCCGCTGTCGCCGCACCGCCCCCTCGCTCGCTCTCT GCGCGCGGAGTCACCCAGTCACACTCCCGGCACCCCGAGCCCTTCCTCCGGAGCTGCTGC TTCTACTTTGGCTGCTATCGCCGCCGCCGCGGGTGGCCCGCTGCTGACTGGGCTCGCCGG GAGACGGAGAAGCACTTTTTGGCCCTCCCTCAGCAGCTCTCACACCCCAACTTTGCCGCC GCCGCCGCGCCTGCCCTCGCAGCGGCGCTCGGCCGCACATTGTGGGGGCGCACGCCGGGA GGCTCCGCAAGACCGTGGAGGCAGGAAACGGCACTACTGCGCTTCTGCCTCGGCTCTTTG TTGTTCGCTTTGGATGGTTCTTGAAAGTGTCTGAGCCTCCTCGGAAATCCTGGGGCCGGA GAAGACAAACCTTGGAATTCTTCCTCTGCAAAAGTCTCTGAGATACTGACAAGCGTCCGG AAAGGTCGACGAGTAATTGCCCTGAAAACTCTTGGCTAATTGACCCACGTTGCTTATATT AAGCCTTTGTGTGTGGTGTGTGGCTTCATACATTTGGGGACCCTATTTCCACTCCCTCCT CTTGGCATGAGACTGTATACAGGATCCACCCGAGGACAATGATTGCGGAGCCCGCTCACT TTTACCTGTTTGGATTAATATGTCTCTGTTCAGGCTCCCGTCTTCGTCAGGAAGATTTTC CACCTCGCATTGTTGAACACCCTTCAGACCTGATTGTCTCAAAAGGAGAACCTGCAACTT TGAACTGCAAAGCTGAAGGCCGCCCCACACCCACTATTGAATGGTACAAAGGGGGAGAGA GAGTGGAGACAGACAAAGATGACCCTCGCTCACACCGAATGTTGCTGCCGAGTGGATCTT TATTTTTCTTACGTATAGTACATGGACGGAAAAGTAGACCTGATGAAGGAGTCTATGTCT GTGTAGCAAGGAATTACCTTGGAGAGGCTGTGAGCCACAATGCATCGCTGGAAGTAGCCA TACTTCGGGATGACTTCAGACAAAACCCTTCGGATGTCATGGTTGCAGTAGGAGAGCCTG CAGTAATGGAATGCCAACCTCCACGAGGCCATCCTGAGCCCACCATTTCATGGAAGAAAG ATGGCTCTCCACTGGATGATAAAGATGAAAGAATAACTATACGAGGAGGAAAGCTCATGA TCACTTACACCCGTAAAAGTGACGCTGGCAAATATGTTTGTGTTGGTACCAATATGGTTG GGGAACGTGAGAGTGAAGTAGCCGAGCTGACTGTCTTAGAGAGACCATCATTTGTGAAGA GACCCAGTAACTTGGCAGTAACTGTGGATGACAGTGCAGAATTTAAATGTGAGGCCCGAG GTGACCCTGTACCTACAGTACGATGGAGGAAAGATGATGGAGAGCTGCCCAAATCCAGAT ATGAAATCCGAGATGATCATACCTTGAAAATTAGGAAGGTGACAGCTGGTGACATGGGTT CATACACTTGTGTTGCAGAAAATATGGTGGGCAAAGCTGAAGCATCTGCTACTCTGACTG TTCAAGTTGGGTCTGAACCTCCACATTTTGTTGTGAAACCCCGTGACCAGGTTGTTGCTT TGGGACGGACTGTAACTTTTCAGTGTGAAGCAACCGGAAATCCTCAACCAGCTATTTTCT GGAGGAGAGAAGGGAGTCAGAATCTACTTTTCTCATATCAACCACCACAGTCATCCAGCC GATTTTCAGTCTCCCAGACTGGCGACCTCACAATTACTAATGTCCAGCGATCTGATGTTG GTTATTACATCTGCCAGACTTTAAATGTTGCTGGAAGCATCATCACAAAGGCATATTTGG AAGTTACAGATGTGATTGCAGATCGGCCTCCCCCAGTTATTCGACAAGGTCCTGTGAATC AGACTGTAGCCGTGGATGGCACTTTCGTCCTCAGCTGTGTGGCCACAGGCAGTCCAGTGC CCACCATTCTGTGGAGAAAGGATGGAGTCCTCGTTTCAACCCAAGACTCTCGAATCAAAC AGTTGGAGAATGGAGTACTGCAGATCCGATATGCTAAGCTGGGTGATACTGGTCGGTACA CCTGCATTGCATCAACCCCCAGTGGTGAAGCAACATGGAGTGCTTACATTGAAGTTCAAG AATTTGGAGTTCCAGTTCAGCCTCCAAGACCTACTGACCCAAATTTAATCCCTAGTGCCC CATCAAAACCTGAAGTGACAGATGTCAGCAGAAATACAGTCACATTATCGTGGCAACCAA ATTTGAATTCAGGAGCAACTCCAACATCTTATATTATAGAAGCCTTCAGCCATGCATCTG GTAGCAGCTGGCAGACCGTAGCAGAGAATGTGAAAACAGAAACATCTGCCATTAAAGGAC TCAAACCTAATGCAATTTACCTTTTCCTTGTGAGGGCAGCTAATGCATATGGAATTAGTG ATCCAAGCCAAATATCAGATCCAGTGAAAACACAAGATGTCCTACCAACAAGTCAGGGGG TGGACCACAAGCAGGTCCAGAGAGAGCTGGGAAATGCTGTTCTGCACCTCCACAACCCCA CCGTCCTTTCTTCCTCTTCCATCGAAGTGCACTGGACAGTAGATCAACAGTCTCAGTATA TACAAGGATATAAAATTCTCTATCGGCCATCTGGAGCCAACCACGGAGAATCAGACTGGT TAGTTTTTGAAGTGAGGACGCCAGCCAAAAACAGTGTGGTAATCCCTGATCTCAGAAAGG GAGTCAACTATGAAATTAAGGCTCGCCCTTTTTTTAATGAATTTCAAGGAGCAGATAGTG AAATCAAGTTTGCCAAAACCCTGGAAGAAGCACCCAGTGCCCCACCCCAAGGTGTAACTG TATCCAAGAATGATGGAAACGGAACTGCAATTCTAGTTAGTTGGCAGCCACCTCCAGAAG ACACTCAAAATGGAATGGTCCAAGAGTATAAGGTTTGGTGTCTGGGCAATGAAACTCGAT ACCACATCAACAAAACAGTGGATGGTTCCACCTTTTCCGTGGTCATTCCCTTTCTTGTTC CTGGAATCCGATACAGTGTGGAAGTGGCAGCCAGCACTGGGGCTGGGTCTGGGGTAAAGA GTGAGCCTCAGTTCATCCAGCTGGATGCCCATGGAAACCCTGTGTCACCTGAGGACCAAG TCAGCCTCGCTCAGCAGATTTCAGATGTGGTGAAGCAGCCGGCCTTCATAGCAGGTATTG GAGCAGCCTGTTGGATCATCCTCATGGTCTTCAGCATCTGGCTTTATCGACACCGCAAGA AGAGAAACGGACTTACTAGTACCTACGCGGGTATCAGAAAAGTAACTTACCAGAGAGGAG GCGAAGCTGTCAGCAGTGGAGGGAGGCCTGGACTTCTCAACATCAGTGAACCTGCCGCGC AGCCATGGCTGGCAGACACGTGGCCTAATACTGGCAACAACCACAATGACTGCTCCATCA GCTGCTGCACGGCAGGCAATGGAAACAGCGACAGCAACCTCACTACCTACAGTCGCCCAG CTGATTGTATAGCAAATTATAACAACCAACTGGATAACAAACAAACAAATCTGATGCTCC CTGAGTCAACTGTTTATGGTGATGTGGACCTTAGTAACAAAATCAATGAGATGAAAACCT TCAATAGCCCAAATCTGAAGGATGGGCGTTTTGTCAATCCATCAGGGCAGCCTACTCCTT ACGCCACCACTCAGCTCATCCAGTCAAACCTCAGCAACAACATGAACAATGGCAGCGGGG ACTCTGGCGAGAAGCACTGGAAACCACTGGGACAGCAGAAACAAGAAGTGGCACCAGTTC AGTACAACATCGTGGAGCAAAACAAGCTGAACAAAGATTATCGAGCAAATGACACAGTTC CTCCAACTATCCCATACAACCAATCATACGACCAGAACACAGGAGGATCCTACAACAGCT CAGACCGGGGCAGTAGTACATCTGGGAGTCAGGGGCACAAGAAAGGGGCAAGAACACCCA AGGTACCAAAACAGGGTGGCATGAACTGGGCAGACCTGCTTCCTCCTCCCCCAGCACATC CTCCTCCACACAGCAATAGCGAAGAGTACAACATTTCTGTAGATGAAAGCTATGACCAAG AAATGCCATGTCCCGTGCCACCAGCAAGGATGTATTTGCAACAAGATGAATTAGAAGAGG AGGAAGATGAACGAGGCCCCACTCCCCCTGTTCGGGGAGCAGCTTCTTCTCCAGCTGCCG TGTCCTATAGCCATCAGTCCACTGCCACTCTGACTCCCTCCCCACAGGAAGAACTCCAGC CCATGTTACAGGATTGTCCAGAGGAGACTGGCCACATGCAGCACCAGCCCGACAGGAGAC GGCAGCCTGTGAGTCCTCCTCCACCACCACGGCCGATCTCCCCTCCACATACCTATGGCT ACATTTCAGGACCCCTGGTCTCAGATATGGATACGGATGCGCCAGAAGAGGAAGAAGACG AAGCCGACATGGAGGTAGCCAAGATGCAAACCAGAAGGCTTTTGTTACGTGGGCTTGAGC AGACACCTGCCTCCAGTGTTGGGGACCTGGAGAGCTCTGTCACGGGGTCCATGATCAACG GCTGGGGCTCAGCCTCAGAGGAGGACAACATTTCCAGCGGACGCTCCAGTGTTAGTTCTT CGGACGGCTCCTTTTTCACTGATGCTGACTTTGCCCAGGCAGTCGCAGCAGCGGCAGAGT ATGCTGGTCTGAAAGTAGCACGACGGCAAATGCAGGATGCTGCTGGCCGTCGACATTTTC ATGCGTCTCAGTGCCCTAGGCCCACAAGTCCCGTGTCTACAGACAGCAACATGAGTGCCG CCGTAATGCAGAAAACCAGACCAGCCAAGAAACTGAAACACCAGCCAGGACATCTGCGCA GAGAAACCTACACAGATGATCTTCCACCACCTCCTGTGCCGCCACCTGCTATAAAGTCAC CTACTGCCCAATCCAAGACACAGCTGGAAGTACGACCTGTAGTGGTGCCAAAACTCCCTT CTATGGATGCAAGAACAGACAGATCATCAGACAGAAAAGGAAGCAGTTACAAGGGGAGAG AAGTGTTGGATGGAAGACAGGTTGTTGACATGCGAACAAATCCAGGTGATCCCAGAGAAG CACAGGAACAGCAAAATGACGGGAAAGGACGTGGAAACAAGGCAGCAAAACGAGACCTTC CACCAGCAAAGACTCATCTCATCCAAGAGGATATTCTACCTTATTGTAGACCTACTTTTC CAACATCAAATAATCCCAGAGATCCCAGTTCCTCAAGCTCAATGTCATCAAGAGGATCAG GAAGCAGACAAAGAGAACAAGCAAATGTAGGTCGAAGAAATATTGCAGAAATGCAGGTAC TTGGAGGATATGAAAGAGGAGAAGATAATAATGAAGAATTAGAGGAAACTGAAAGCTGAA GACAACCAAGAGGCTTATGAGATCTAATGTGAAAATCATCACTCAAGATGCCTCCTGTCA GATGACACATGACGCCAGATAAAATGTTCAGTGCAATCAGAGTGTACAAATTGTCGTTTT TATTCCTCTTATTGGGATATCATTTTAAAAACTTTATTGGGTTTTTATTGTTGTTGTTTG ATCCCTAACCCTACAAAGAGCCTTCCTATTCCCCTCGCTGTTGGAGCAAACCATTATACC TTACTTCCAGCAAGCAAAGTGCTTTGACTTCTTGCTTCAGTCATCAGCCAGCAAGAGGGA ACAAAACTGTTCTTTTGCATTTTGCCGCTGAGATATGGCATTGCACTGCTTATATGCCAA GCTAATTTATAGCAAGATATTGATCAAATATAGAAAGTTGATATTCAACCTCACAAGGGC TCTCAAAGTATAATCTTTCTATAGCCAACTGCTAATGCAAATTAAAACATATTTCATTTT AACATGATTTCAAAATCAGTTTTTCATACTACCCTTTGCTGGAAGAAACTAAAAATATAG CAAATGCAGAACCACAAACAATTCGAATGGGGTAGAAACATTGTAAATATTTACTCTTTG CAAACCCTGGTGGTATTTTATTTTGGCTTCATTTCAATCATTGAAGTATATTCTTATTGG AAATGTACTTTTGGATAAGTAGGGCTAAGCCAGTTGGATCTCTGGTTGTCTAGTCATTGT CATAAGTAAACCTAGTAAAACCTTGTTCTATTTTTCAATCATCAAAAAGTAATTATAAAT ACGTATTACAAACAAGTGGATGTTTTTAATGACCAATTGAGTAAGAACATCCCTGTCTTA ACTGGCCTAAATTTCTTCTGGTAGTGTCAGTTCAACTTTCAGAAGTGCCACTTAAGGAAG TTTGATTTTTGTTTTTGTAATGCACTGTTTTTAATCTCTCTCTCTTTTTTTTTTTTTTTT TGGTTTTAAAAGCACAATCACTAAACTTTATTTGTAAACCATTGTAACTATTAACCTTTT TTGTCTTATTGAAAAAAAAAATGTTGAGAAGCGTTTTTAACCTGTTTTGTTAATGCTCTA TGTTTGTATTTGGAATATTTGAATAATGACAGATGGTGAAGTAACATGCATACTTTATTG TGGGCCATGAACCAAATGGTTCTTACTTTTCCTGGACTTAAAGAAAAAAAGAGGTTTAAG TTTGTTGTGGCCAATGTCGAAACCTACAAGATTTCCTTAAAATCTCTAATAGAGGCATTA CTTGCTTTCAATTGACAAATGATGCCCTCTGACTAGTAGATTTCTATGATCCTTTTTTGT CATTTTATGAATATCATTGATTTTATAATTGGTGCTATTTGAAGAAAAAAATGTACATTT ATTCATAGATAGATAAGTATCAGGTCTGACCCCAGTGGAAAACAAAGCCAAACAAAACTG AACCACAAAAAAAAAGGCTGGTGTTCACCAAAACCAAACTTGTTCATTTAGATAATTTGA AAAAGTTCCATAGAAAAGGCGTGCAGTACTAAGGGAACAATCCATGTGATTAATGTTTTC ATTATGTTCATGTAAGAAGCCCCTTATTTTTAGCCATAATTTTGCATACTGAAAATCCAA TAATCAGAAAAGTAATTTTGTCACATTATTTATTAAAAATGTTCTCAAATACATAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >6091 : length: 1654 MKWKHVPFLVMISLLSLSPNHLFLAQLIPDPEDVERGNDHGTPIPTSDNDDNSLGYTGSR LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVM VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC VGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDG ELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKP RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITN VQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCV ATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWS AYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIE AFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDV LPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGAN HGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSA PPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSV VIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSLAQQISDVVKQP AFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIRKVPSFTFTPTVTYQRGGEAVS SGGRPGLLNISEPAAQPWLADTWPNTGNNHNDCSISCCTAGNGNSDSNLTTYSRPADCIA NYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQ LIQSNLSNNMNNGSGDSGEKHWKPLGQQKQEVAPVQYNIVEQNKLNKDYRANDTVPPTIP YNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHS NSEEYNISVDESYDQEMPCPVPPARMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSH QSTATLTPSPQEELQPMLQDCPEETGHMQHQPDRRRQPVSPPPPPRPISPPHTYGYISGP LVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSA SEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDAAGRRHFHASQC PRPTSPVSTDSNMSAAVMQKTRPAKKLKHQPGHLRRETYTDDLPPPPVPPPAIKSPTAQS KTQLEVRPVVVPKLPSMDARTDRSSDRKGSSYKGREVLDGRQVVDMRTNPGDPREAQEQQ NDGKGRGNKAAKRDLPPAKTHLIQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQR EQANVGRRNIAEMQVLGGYERGEDNNEELEETES |