| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5978 |
Name | REST |
Synonym | NRSF|XBR;RE1-silencing transcription factor;REST;RE1-silencing transcription factor |
Definition | RE1-silencing transcription factor variant E1a/E2/E3/E4c|RE1-silencing transcription factor variant E1a/E2/E3/E5|RE1-silencing transcription factor variant E1a/E2/E3/N3a/E4i|RE1-silencing transcription factor variant E1a/E2/E3/N3c/E4|RE1-silencing transcr |
Position | 4q12 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Huntington's disease;KEGG PATHWAY;hsa05016 |
Disease | Down syndrome;FunDO |
Disease | Mental retardation;FunDO |
Disease | Cerebellar disease;FunDO |
Disease | NEUROLOGICAL;GAD |
Disease | cognitive ability;GAD |
External Links | |
Links to Entrez Gene | 5978 |
Links to all GeneRIF Items | 5978 |
Links to iHOP | 5978 |
Sequence Information | |
Nucleotide Sequence | >5978 : length: 7333 GGCGGCGGCGGCGGCGCGGACTGGGTGCGCGGCGCAGCGTCCTGTGTTGGAATGTGCGGC TGCCGCGAGCTCGCGGCGCAGCAGCGGAGCGAGCGCCGCCGAGGCCCGGGGCCCCAGACC CTGGCGGCGGCTGCCGCAGCCGAGACGGCAGGGCGAGGCCCGGAGGCCTGAGCACCCTCT GCAGCCCCACTCCTGGGCCTTCTTGGTCCACGACGGCCCCAGCACCCAACTTTACCACCC TCCCCCACCTCTCCCCCGAAACTCCAGCAACAAAGAAAAGTAGTCGGAGAAGGAGCGGCG ACTCAGGGTCGCCCGCCCCTCCTCACCGAGGAAGGCCGAATACAGTTATGGCCACCCAGG TAATGGGGCAGTCTTCTGGAGGAGGAGGGCTGTTTACCAGCAGTGGCAACATTGGAATGG CCCTGCCTAACGACATGTATGACTTGCATGACCTTTCCAAAGCTGAACTGGCCGCACCTC AGCTTATTATGCTGGCAAATGTGGCCTTAACTGGGGAAGTAAATGGCAGCTGCTGTGATT ACCTGGTCGGTGAAGAAAGACAGATGGCAGAACTGATGCCGGTTGGGGATAACAACTTTT CAGATAGTGAAGAAGGAGAAGGACTTGAAGAGTCTGCTGATATAAAAGGTGAACCTCATG GACTGGAAAACATGGAACTGAGAAGTTTGGAACTCAGCGTCGTAGAACCTCAGCCTGTAT TTGAGGCATCAGGTGCTCCAGATATTTACAGTTCAAATAAAGATCTTCCCCCTGAAACAC CTGGAGCGGAGGACAAAGGCAAGAGCTCGAAGACCAAACCCTTTCGCTGTAAGCCATGCC AATATGAAGCAGAATCTGAAGAACAGTTTGTGCATCACATCAGAGTTCACAGTGCTAAGA AATTTTTTGTGGAAGAGAGTGCAGAGAAGCAGGCAAAAGCCAGGGAATCTGGCTCTTCCA CTGCAGAAGAGGGAGATTTCTCCAAGGGCCCCATTCGCTGTGACCGCTGCGGCTACAATA CTAATCGATATGATCACTATACAGCACACCTGAAACACCACACCAGAGCTGGGGATAATG AGCGAGTCTACAAGTGTATCATTTGCACATACACAACAGTGAGCGAGTATCACTGGAGGA AACATTTAAGAAACCATTTTCCAAGGAAAGTATACACATGTGGAAAATGCAACTATTTTT CAGACAGAAAAAACAATTATGTTCAGCATGTTAGAACTCATACAGGAGAACGCCCATATA AATGTGAACTTTGTCCTTACTCAAGTTCTCAGAAGACTCATCTAACTAGACATATGCGTA CTCATTCAGGTGAGAAGCCATTTAAATGTGATCAGTGCAGTTATGTGGCCTCTAATCAAC ATGAAGTAACCCGCCATGCAAGACAGGTTCACAATGGGCCTAAACCTCTTAATTGCCCAC ACTGTGATTACAAAACAGCAGATAGAAGCAACTTCAAAAAACATGTAGAGCTACATGTGA ACCCACGGCAGTTCAATTGCCCTGTATGTGACTATGCAGCTTCCAAGAAGTGTAATCTAC AGTATCACTTCAAATCTAAGCATCCTACTTGTCCTAATAAAACAATGGATGTCTCAAAAG TGAAACTAAAGAAAACCAAAAAACGAGAGGCTGACTTGCCTGATAATATTACCAATGAAA AAACAGAAATAGAACAAACAAAAATAAAAGGGGATGTGGCTGGAAAGAAAAATGAAAAGT CCGTCAAAGCAGAGAAAAGAGATGTCTCAAAAGAGAAAAAGCCTTCTAATAATGTGTCAG TGATCCAGGTGACTACCAGAACTCGAAAATCAGTAACAGAGGTGAAAGAGATGGATGTGC ATACAGGAAGCAATTCAGAAAAATTCAGTAAAACTAAGAAAAGCAAAAGGAAGCTGGAAG TTGACAGCCATTCTTTACATGGTCCTGTGAATGATGAGGAATCTTCAACAAAAAAGAAAA AGAAGGTAGAAAGCAAATCCAAAAATAATAGTCAGGAAGTGCCAAAGGGTGACAGCAAAG TGGAGGAGAATAAAAAGCAAAATACTTGCATGAAAAAAAGTACAAAGAAGAAAACTCTGA AAAATAAATCAAGTAAGAAAAGCAGTAAGCCTCCTCAGAAGGAACCTGTTGAGAAGGGAT CTGCTCAGATGGACCCTCCTCAGATGGGGCCTGCTCCCACAGAGGCGGTTCAGAAGGGGC CCGTTCAGGTGGAGCCGCCACCTCCCATGGAGCATGCTCAGATGGAGGGTGCCCAGATAC GGCCTGCTCCTGACGAGCCTGTTCAGATGGAGGTGGTTCAGGAGGGGCCTGCTCAGAAGG AGCTGCTGCCTCCCGTGGAGCCTGCTCAGATGGTGGGTGCCCAAATTGTACTTGCTCACA TGGAGCTGCCTCCTCCCATGGAGACTGCTCAGACGGAGGTTGCCCAAATGGGGCCTGCTC CCATGGAACCTGCTCAGATGGAGGTTGCCCAGGTAGAATCTGCTCCCATGCAGGTGGTCC AGAAGGAGCCTGTTCAGATGGAGCTGTCTCCTCCCATGGAGGTGGTCCAGAAGGAGCCTG TTCAGATAGAGCTGTCTCCTCCCATGGAGGTGGTCCAGAAGGAACCTGTTAAGATAGAGC TGTCTCCTCCCATAGAGGTGGTCCAGAAGGAGCCTGTTCAGATGGAGTTGTCTCCTCCCA TGGGGGTGGTTCAGAAGGAGCCTGCTCAGAGGGAGCCACCTCCTCCCAGAGAGCCTCCCC TTCACATGGAGCCAATTTCCAAAAAGCCTCCTCTCCGAAAAGATAAAAAGGAAAAGTCTA ACATGCAGAGTGAAAGGGCACGGAAGGAGCAAGTCCTTATTGAAGTTGGCTTAGTGCCTG TTAAAGATAGCTGGCTTCTAAAGGAAAGTGTAAGCACAGAGGATCTCTCACCACCATCAC CACCACTGCCAAAGGAAAATTTAAGAGAAGAGGCATCAGGAGACCAAAAATTACTCAACA CAGGTGAAGGAAATAAAGAAGCCCCTCTTCAGAAAGTAGGAGCAGAAGAGGCAGATGAGA GCCTACCTGGTCTTGCTGCTAATATCAACGAATCTACCCATATTTCATCCTCTGGACAAA ACTTGAATACGCCAGAGGGTGAAACTTTAAATGGTAAACATCAGACTGACAGTATAGTTT GTGAAATGAAAATGGACACTGATCAGAACACAAGAGAGAATCTCACTGGTATAAATTCAA CAGTTGAAGAACCAGTTTCACCAATGCTTCCCCCTTCAGCAGTAGAAGAACGTGAAGCAG TGTCCAAAACTGCACTGGCATCACCTCCTGCTACAATGGCAGCAAATGAGTCTCAGGAAA TTGATGAAGATGAAGGCATCCACAGCCATGAAGGAAGTGACCTAAGTGACAACATGTCAG AGGGTAGTGATGATTCTGGATTGCATGGGGCTCGGCCAGTTCCACAAGAATCTAGCAGAA AAAATGCAAAGGAAGCCTTGGCAGTCAAAGCGGCTAAGGGAGATTTTGTTTGTATCTTCT GTGATCGTTCTTTCAGAAAGGGAAAAGATTACAGCAAACACCTCAATCGCCATTTGGTTA ATGTGTACTATCTTGAAGAAGCAGCTCAAGGGCAGGAGTAATGAAACTTTGAACAAGGTT TCAGTTCTTAGTTTGTAAGGTATATTACATTTTATATTCATTTATGATAGCAGACAACCT TTTAAGATTGCTTTAATTAGTATCTGATGTTGATTTTTAAGTGGCATTCTTTTCCTTAGG ACTTTTTATGTATACCTGTTGATTGTTGTGTAAATTTTAGTAAATCTAAGAGAGTGTACT AAACCAGCAGGTATCTGTTAGCTTATGTGTTTAATTGAAATTAGAAGGCTAAGATGGTAT AACAGCATTTTATTGCTTTGTCCAGCTACAACTTGTCATTTTTTTCTCCATGTCTTATCT TCCTGTTTCACTTTAGTTTATTCTTCGTTTTTTATTGAGATCTATAAAAAATTGGCTTAC TTAATAGCAAATTACTTGAAGAATTTGCCTGCTTTATATAAAGTTAGCACTTTAAGATTT TTTTTTTTAGAGATGAGAAGACATTTAAATTGAAGAAAAATTCCCCCAGCAATAGACAGT CTATCAGTCCAAGTATTTACTTCCTGAGTTTTGATCAATATTTTTTATTTGTGTATGTTA ATCGTCATAAAAACAGTGATTTTGGTGTGTTTTTTATTTTGGTGCTTTAATGGCTTAAGA TGTTGCACATTTTTTTTTTCTTTTGGTTTCTGTTTATGTTTTTTTGCCTATGCAGTTAAA TTTTTCCTAGAAATAGCATTTGTGTTGAACAGTAACACTTTATACATATATATATGCATG TTTATTTTGTTTGGCGTCTTTGGAGGGATGCTTTTAGACTTGTTTGCAAAAGGGCAGTTT TCTTTTTCTTTGCTGCAGTTGTCTATTTTGCAGAATAATAGTGTGTGCAAGTTTGTGAGC AAATGAAATATGCAGGTTCAATCTATTGATTTTGATTTTTACATCTTATATCTATGCCAG AATCTGTATTTCATATAACTTATTTATTTCGAATGGATGTAGTAAATTCACAGCTATCAG TTTTGATTTTGCAATAAATAAACCACTAGGTTGCATGTCGAACAAATTTTTATCTCAAAT ACCAACCATCAGTTTTTTTTTTCATGTGTTTTGGTACAGCTAATTCCTAATTGTAGAGTG TTAAATGTTTGAGGAGAACCTTTTCTCATAGATGGTTGGTGTTCATATGGCTACTTTACA ATAAAGAGAACTGTAAGTGATATTTGGAAACTACAAACCTGGAATTAGGAGATATAATTA TTCCTTCAAGTTTTATAGAATATCACTTGGGAGATTCCAAAGCCATAGCTATTACGCGGC AAACCTAGGATAAGAAAGGTAGTATGAGTGCTGGTAGACCAGCTGCAACTTTCCTATACA GTGAAAAAGGCTGGTGAAACAAGTACAGTCCAGATTTTTTAAAATCATACTTTCTCAGGG ATCTCCACAAACTGGTGGGTGTCCTGGCTGTCTGTGTGATAGCCTCTTTCTATAGGTGAG GCCTCAAATGAATTGCAGCTATCCTGGTGTTCCTATGAGGGCACTTTGTATGAAAAAGGG CATGTACTCCAAAACATTTTTGTAGGTTCTTTGGCCAGTTGCCAAAGAGTGTGAAAGAAT CCAATAGAGGATTTTTCTTACTGATAGCAGTCATTCATTGCAGTAAAATAAAATATGATC CCATTAGGGAATCTTGAATTCTGACCTCCCATACTCCGTTTTGAAATAACCACTTTATAT TTCATTTTTTAAAAATCTGATGATCTCTTTGAGGCAGGTTTCAGATTTGGCAGTACAACA TGAAAGATTAGGAAAAGCATTAATAACGTGTGGGTGGAAAGCTTGTTAAAAATCTGAGAG TGAAGTTTGAGTTAAAAGTTGTTTGAACATGGCATTGACTGGGAGGCCAAAGATTTAAAG AAGCGGAAGATTCTTCTCTTAAGACATGAGGAGTAAGTTGTGTGATAATGGTATGTGTTT TGTGTGCATGAATGGACATTGTAAATGTTGAATTCTAGGCTCCGACAATCATTGTCAACA GAAGATCAAGCTGCAAATATTTATGTTTTAAAACTTAAATTATAAAGCTAGTTAAGTCTT TCTAATGACTAGTTTTAATGTTCATGGGTACATTTTACCTAAGTTACCGTTTACATTGTA TAGAAAAAGATACATCTTAAGCACAGATTGGTTATTAGGAATTAGTTTGGGGAAGAGGTT TTTTTGTGGATTCTTTCATACTGCAAAGAAAAACCATTTGCCTTTTGGGGAATTGAGCTA ACTTCTAATCTAGTCTTAAGACTAGAATGCTAAAAACAAAAACATGAAGGAAATTAAAAC CCCTTATTATTAAATTGATTTGTAAAAACATTGTTACTGGAAATTTATTGGACTTGAGGC CTTCCTCCAGAAAATAAGGACTTGATTGTCAGGCCTATATTAGGTTCTGAACCTTAATGC CATGTATTTGTACTTACTAAAAATTGTTTCAATGAAAAGTACATTAGCAGTATGAACTTC TGGTCCAGTTGGAAGTTTTTCCATTTGAAAAATGTGATGTTTGCATGGAACTGTTTGAAA CTTTTTTATTTTCTAGTCCCCCTCCCCCACACTGGATAGAATTTAGCCTAGAATTTTCCC TTTGGATAAAAGAACAAAAATTGAACATGTTATTTGTAAATTGATGTTTAGTAATTAGTG ATAAACTTGAAATACTAGCATATATTATAAGCCTTAATCTTAGGTAGTCTTATGAAAATG AATCTCTTAACTATCTTTTGAACCTGTATTCACATTGGTTTTCAAGATATTTTAAGTTAT ATTTTTTCCTCTTTTCAGAGCTGCTTCTTATTCTGGGGCTACTTTTTTTTTTAGTTGTGT AATTCACAAAGGGCTGCATTTTTTTTTTTTTTTAATAAGGCTTATAACTATGGCTGGATC TTTTGCTCTAGTCTTCTAAGAAGGGCCATTTTATTTTTTAGAGTCACTTCTAAAGTCATG TGGTAATTAACTTTGGAGACTGTTTTGCGTATGAGTGCTGATACAAATTAAAACCCAAGT AGACCTCATTGCATGTCACCCTATGAATGTTGACAATGGAAGGAATACCTTGCCTGTAGT ATACTGTCACTTCTGGATTGATAAGCTGAGGAAGAAAGTTAAGTTTCTTTTTTACATAAG TCAGAAAAACTTACAGCTGGTGTTCCTAGTTTCCTGGTTGACCTCAGCAGATGAAGTGAA CAGATAGTGTTAATTCAGATTGAAGAAATTATCTGAATCTTGGTTTGTGTAGATTTACAA TCTACATGCAATATTAACTAAATCAGATAGCTTTTACAGTTTCACATGTGTACATAGGTT CCCTCCCGGTCCCTTCCATATCCATTAGTTATTGAACTTTCTAAACTGGCATTGAAACAT TACAACAATGTTTTGTTGCACCAATTTTATAAACTTAAGCAGTGCAATACGTGTTACTTT TCTGAGGCAAACCAAAGGTAAATTTCTCAAGGTTCTTGCTGCCTTCTTTAGCAGCATTTG ATGGAAGATCTTTTATACATTTGTAATAGATAAAAATAAACCAGATTGCAAATCCTTTTT TAAAATCCTAAACCATGTACCAAGTTTTTGGTCCAAATTATGTAGGATAAGTTAAACTTA AATTGCATTCTATTAACCAATATGAGTGTATTTCTGTAAGCATAGTTATGTTGAAATAAA GTTTTAAAAACCA |
Protein Sequence | >5978 : length: 1097 MATQVMGQSSGGGGLFTSSGNIGMALPNDMYDLHDLSKAELAAPQLIMLANVALTGEVNG SCCDYLVGEERQMAELMPVGDNNFSDSEEGEGLEESADIKGEPHGLENMELRSLELSVVE PQPVFEASGAPDIYSSNKDLPPETPGAEDKGKSSKTKPFRCKPCQYEAESEEQFVHHIRV HSAKKFFVEESAEKQAKARESGSSTAEEGDFSKGPIRCDRCGYNTNRYDHYTAHLKHHTR AGDNERVYKCIICTYTTVSEYHWRKHLRNHFPRKVYTCGKCNYFSDRKNNYVQHVRTHTG ERPYKCELCPYSSSQKTHLTRHMRTHSGEKPFKCDQCSYVASNQHEVTRHARQVHNGPKP LNCPHCDYKTADRSNFKKHVELHVNPRQFNCPVCDYAASKKCNLQYHFKSKHPTCPNKTM DVSKVKLKKTKKREADLPDNITNEKTEIEQTKIKGDVAGKKNEKSVKAEKRDVSKEKKPS NNVSVIQVTTRTRKSVTEVKEMDVHTGSNSEKFSKTKKSKRKLEVDSHSLHGPVNDEESS TKKKKKVESKSKNNSQEVPKGDSKVEENKKQNTCMKKSTKKKTLKNKSSKKSSKPPQKEP VEKGSAQMDPPQMGPAPTEAVQKGPVQVEPPPPMEHAQMEGAQIRPAPDEPVQMEVVQEG PAQKELLPPVEPAQMVGAQIVLAHMELPPPMETAQTEVAQMGPAPMEPAQMEVAQVESAP MQVVQKEPVQMELSPPMEVVQKEPVQIELSPPMEVVQKEPVKIELSPPIEVVQKEPVQME LSPPMGVVQKEPAQREPPPPREPPLHMEPISKKPPLRKDKKEKSNMQSERARKEQVLIEV GLVPVKDSWLLKESVSTEDLSPPSPPLPKENLREEASGDQKLLNTGEGNKEAPLQKVGAE EADESLPGLAANINESTHISSSGQNLNTPEGETLNGKHQTDSIVCEMKMDTDQNTRENLT GINSTVEEPVSPMLPPSAVEEREAVSKTALASPPATMAANESQEIDEDEGIHSHEGSDLS DNMSEGSDDSGLHGARPVPQESSRKNAKEALAVKAAKGDFVCIFCDRSFRKGKDYSKHLN RHLVNVYYLEEAAQGQE |