| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 586 |
Name | BCAT1 |
Synonym | BCATC|BCT1|ECA39|MECA39|PNAS121|PP18;branched chain amino-acid transaminase 1, cytosolic;BCAT1;branched chain amino-acid transaminase 1, cytosolic |
Definition | branched chain aminotransferase 1, cytosolic|branched-chain-amino-acid aminotransferase, cytosolic|placental protein 18 |
Position | 12p12.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Valine, leucine and isoleucine degradation;KEGG PATHWAY;hsa00280 |
Pathway | Pantothenate and CoA biosynthesis;KEGG PATHWAY;hsa00770 |
Pathway | Validated targets of C-MYC transcriptional activation;PID Curated;200045 |
Pathway | Valine, leucine and isoleucine biosynthesis;KEGG PATHWAY;hsa00290 |
Pathway | valine degradation I;BioCyc;VALDEG-PWY |
Pathway | isoleucine biosynthesis I (from threonine);BioCyc;ILEUSYN-PWY |
Pathway | Metabolism of amino acids and derivatives;Reactome;REACT:13 |
Pathway | Valine biosynthesis;PANTHER;P02785 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | isoleucine degradation I;BioCyc;ILEUDEG-PWY |
Pathway | Leucine biosynthesis;PANTHER;P02749 |
Pathway | Isoleucine biosynthesis;PANTHER;P02748 |
Pathway | leucine degradation I;BioCyc;LEU-DEG2-PWY |
Pathway | Alanine biosynthesis;PANTHER;P02724 |
Disease | Advanced cancer;FunDO |
Disease | Colon cancer;FunDO |
Disease | Hyperleucinemia-isoleucinemia or hypervalinemia;OMIM |
Disease | Nasopharyngeal cancer;FunDO |
External Links | |
Links to Entrez Gene | 586 |
Links to all GeneRIF Items | 586 |
Links to iHOP | 586 |
Sequence Information | |
Nucleotide Sequence | >586 : length: 9682 AGTAGGGAGGTGGGCAGGAGCCAGTGATGACGGAATGGCAATCACATTTGACCTCTGATC TGTTTATTTCCTCCTCCTTGACGTCTCCATATAAATGTTACACGGGCATCCCCACACTCG GATACGCACCCACAGTGGCTGATTCGGGGGTAACCGTGTCATTTGCTTGCAACACTGGCA CCTCTGCCCTGCACCCCGGGAGTGAGCAGTGAGTGAGGCTCGGGTCTGGGCGCTGGCTCC GAATCTTCGGGCTGGGAGAGACTCCACCATCTGGGGGCGGCCTGGGGGAGCAGCCTTAGT GTCTTCCTGCTGATGCAATCCGCTAGGTCGCGAGTCTCCGCCGCGAGAGGGCCGGTCTGC AATCCAGCCCGCCACGTGTACTCGCCGCCGCCTCGGGCACTGCCCCAGGTCTTGCTGCAG CCGGGACCGCGCTCTGCAGCCGCAGACCCGGTCCACACGGCCAGGGGCTACGACCCTTGG GATCTGCCCTCCGCTCAGCTCGAGCTTCCCTCGTGGCCGACGGAACAATGAAGGATTGCA GTAACGGATGCTCCGCAGAGTGTACCGGAGAAGGAGGATCAAAAGAGGTGGTGGGGACTT TTAAGGCTAAAGACCTAATAGTCACACCAGCTACCATTTTAAAGGAAAAACCAGACCCCA ATAATCTGGTTTTTGGAACTGTGTTCACGGATCATATGCTGACGGTGGAGTGGTCCTCAG AGTTTGGATGGGAGAAACCTCATATCAAGCCTCTTCAGAACCTGTCATTGCACCCTGGCT CATCAGCTTTGCACTATGCAGTGGAATTATTTGAAGGATTGAAGGCATTTCGAGGAGTAG ATAATAAAATTCGACTGTTTCAGCCAAACCTCAACATGGATAGAATGTATCGCTCTGCTG TGAGGGCAACTCTGCCGGTATTTGACAAAGAAGAGCTCTTAGAGTGTATTCAACAGCTTG TGAAATTGGATCAAGAATGGGTCCCATATTCAACATCTGCTAGTCTGTATATTCGTCCTA CATTCATTGGAACTGAGCCTTCTCTTGGAGTCAAGAAGCCTACCAAAGCCCTGCTCTTTG TACTCTTGAGCCCAGTGGGACCTTATTTTTCAAGTGGAACCTTTAATCCAGTGTCCCTGT GGGCCAATCCCAAGTATGTAAGAGCCTGGAAAGGTGGAACTGGGGACTGCAAGATGGGAG GGAATTACGGCTCATCTCTTTTTGCCCAATGTGAAGCAGTAGATAATGGGTGTCAGCAGG TCCTGTGGCTCTATGGAGAGGACCATCAGATCACTGAAGTGGGAACTATGAATCTTTTTC TTTACTGGATAAATGAAGATGGAGAAGAAGAACTGGCAACTCCTCCACTAGATGGCATCA TTCTTCCAGGAGTGACAAGGCGGTGCATTCTGGACCTGGCACATCAGTGGGGTGAATTTA AGGTGTCAGAGAGATACCTCACCATGGATGACTTGACAACAGCCCTGGAGGGGAACAGAG TGAGAGAGATGTTTGGCTCTGGTACAGCCTGTGTTGTTTGCCCAGTTTCTGATATACTGT ACAAAGGCGAGACAATACACATTCCAACTATGGAGAATGGTCCTAAGCTGGCAAGCCGCA TCTTGAGCAAATTAACTGATATCCAGTATGGAAGAGAAGAGAGCGACTGGACAATTGTGC TATCCTGAATGGAAAATAGAGGATACAATGGAAAATAGAGGATACCAACTGTATGCTACT GGGACAGACTGTTGCATTTGAATTGTGATAGATTTCTTTGGCTACCTGTGCATAATGTAG TTTGTAGTATCAATGTGTTACAAGAGTGATTGTTTCTTCATGCCAGAGAAAATGAATTGC AATCATCAAATGGTGTTTCATAACTTGGTAGTAGTAACTTACCTTACCTTACCTAGAAAA ACATTAATGTAAGCCATATAACATGGGATTTTCCTCAATGATTTTAGTGCCTCCTTTTGT ACTTCACTCAGATACTAAATAGTAGTTTATTCTTTAATATAAGTTACATTCTGCTCCTCA AACAAATGCAATTTTTTGTGTGTGTTTGAAAGCTAATTTGAGAAAATTTCATAGGTTACA TTTCCTGCAGCCTATCTTTATCCACAGAAAGTGTTTTCTTTTTTTTAAATCAAGACTTTT AAAACTGGATTTCCTCCCATCACTGTTTTTTGAAGGTCCTCCAAGTCCGTGTTAAGGTAA ATATCTGTTTTCTTCCTGATGTCACAGCCTGAGCATACTCTGTGCATTAGGAAGACCTGA GTGCATTTCCCACCATTGTCCTTTCCACATTATGTTGTAGCTGGCTGGCTGTCAGGCGAC TACAAGACTGAGGGTCTTGTGCCTTATAGATCTTTGTATCCCCCATGGCTGACATATAGT AGGTACTCAGTAAATGGTTTTATAATGAATCAGTGAACATTTTGCTTCTATAGAAGTGTA CCTTCTTTGTTTCTATATTATGAAACCTCTTTATTAGAATTTGTGATTGATTCTGACAGT GTATAGATTTACCTTATATTGTCTTTATTTTCCATGAGCTACTAAGTCATTAGAGATACT CTGAAGCATAGTTAGTTTAGGAAATCACTTCATATTGATTGTATTAGAATTATCTTGGAA TTGAAGATATATCCCTAGAGCAGGGGACCCCAACCCCCAGGCCATGGGCCACACAGCAGG AAGAGGTGAGTGGTGGGCCATTGAGGAGCTTCATCTGTATTTATGGCTACTTCCCATCAC TCGAATTACCACCTGAACTCCACCTCTTGTCAGCTCAGTGGCAGCATTAGATTCTCATAG GAGCACAAATCCTATTGTGAACTCTGCATGCAAGGGATCTAGGCTATGCGCTCCTTATGA GAATCTAATGCTTGATGACCTGAGGTGTAACAGTTTCATCCTGAAACCACCCTTCACCCT GCAGTCTGTGGAAAAATTGTCTTCCACAAAACTGGTCCCTGGTGCCAAAAATGTTGGGGA CCACTGCTCTAGAGAGAGGTCATGATATCATACCAACCAAATGGAAATGACAAATGTTTT ATGTCAAGTGTTAATTGCAGAAATAAATCTTTTTTTTTTTTTTTTGGTAGAAAACAAAGA GGCATACTCTGATTTTTATACTCTGTTTTTGCAGGTGCTCTTTTCTTTGAATGGAGATTT GATGAGCAAGTGGTTAGGATGCAGGGAGAGCTACTATGGGTGATATTTTCCTTGTTTAGG AGCTGTGAGTTAAAATTGTATCCTTTGTGGTTTATCTAAGGAAAGTCAAATCTTGACAGA AAACATTTTTCCTTGGAAGGTCAACTCTCAGACATTGTATTTTGGTTTCCCTCAGTCCTC ATAACTTCCTTCTTGCTGAACATATTTTATTCTCTTTTCAGAGAAGGAAAATAAAAAGGA TTCTAAAAGTTTGATGCATTGGAAAAATTTCCTTGAGGCATTTAGCAACACATAGAAAAT GGGCTTTGATTCTTTTCCAAAACTTTTAGCCATAGGGTCTTTTATAGACAGGGATAGTAA AATGAAAATTGAGAAATATAAGATGAAAAGGAATGATAAAAATATCTTTTAGGGGGCTTT TAATTGGTGATCTGAAATCTTGGGAGAAGCTGTTCTTTTCAGGCCTGAGGTGCTCTTGAC TGTCGCCTGCGCACTGTGTACCCCGAGCAACATTCTAAGGGTGTGCTTTCGCCTTGGCTA ACTCCTTTGACCTCATTCTTCATATAGTAGTCTAGGAAAAAGTTGCAGGTAATTTAAACT GTCTAGTGGTACATAGTAACTAAATTTCTATTCCTATGAGAAATGAGAATTATTTATTTG CCATCAACACATTTTATACTTTGCATCTCCAAATTTATTGTGGCGAGACTTGTCCATTGT GAAAGTTAGAGAACATTATGTTTGTATCATTTCTTTCATAAAACCTCAAGAGCATTTTTA AGCCCTTTTCATCAGACCCAGTGAAAACTAAGGATAGATGTTTAAAAACTGGAGGTCTCC TGATAAGGAGAACACAATCCACCATTGTCATTTAAGTAATAAGACAGGAAATTGACCTTG ACGCTTTCTTGTTAAATAGATTTAACAGGAACATCTGCACATCTTTTTTCCTTGTGCACT ATTTGTTTAATTGCAGTGGATTAATACAGCAAGAGTGCCACATTATAACTAGGCAATTAT CCATTCTTCAAGACTTAGTTATTGTCACACTAATTGATCGTTTAAGGCATAAGATGGTCT AGCATTAGGAACATGTGAAGCTAATCTGCTCAAAAAGATCAACAAATTAATATTGTTGCT GATATTTGCATAATTGGCTGCAATTATTTAATGTTTAATTGGGTTGATCAAATGAGATTC AGCAATTCACAAGTGCATTAATATAAACAGAACTGGTGGCACTTAAAATGATAATGATTA ACTTATATTGCATGTTCTCTTCCTTTCACTTTTTTCAGTTTCTACATTTCAGACCGAGCT TGTCAGCTTTTTTGAAAACACATCAGTAGAAACCAAGATTTTAAAATGAAGTGTCAAGAC AAAGGCAAAACCTGAGCAGTTCCTAAAAAGATTTGCTGTTAGAAATTTTCTTTGTGGCAG TCATTTATTAAGGATTCAACTCGTGATACACCAAAAGAAGAGTTGACTTCAGAGATGTGT TCCATGCTCTCTAGCACAGGAATGAATAAATTTATAACACCTGCTTTAGCCTTTGTTTTC AAAAGCACAAAGGAAAAGTGAAAGGGAAAGAGAAACAAGTGACTGAGAAGTCTTGTTAAG GAATCAGGTTTTTTCTACCTGGTAAACATTCTCTATTCTTTTCTCAAAAGATTGCTGTAA GAAAAAATGTAAGACAAAAAAAAAAAAAAAAAACAAACAGAGGCAGAGGCAGGCAGTAGC AAGAAAGCAGAGCGTAACATCAGCTAGATGGTAACATGCAATGTCAGCTCTCTTGAAGAC ATGGGAAACCTAAGTTACACCTTGGGTTAAAATTCTTCACCATATTAGTTTTGTTGCTTC ATAAAATTTACCTAAGCAAGTGGTCTTGCTTGCCTCAAATCCAAGCAGTCTTGAACACTT GGAGGCAATTAATGAGTATATCTTAGTCAAAAGAATTGTTGGAGCTTTTTATTAAAGCTA CAGTTTCAGTTCTGCTTTTGGGGAATTGTGCTATGAAAGCAGCTGCCAAAATAAGCTCAT TTATTTTCTTCAATCCCACTCAGTGCTCAGTCACTATATTCTGTTTCCTTTTTTTTTTTC AAGTTGCATATTTGGTTTCCCCTTATGATTGGGAAAGATGAATTTTCAGCAGAAAACATT GTTTGTTCACTTTCAAAGAGTGATAGTTTCTAAAACATTTAGAGCAATAAATATTCATCA GAGGTACCAAGTAAGCCGGCAGAAGAGTTAAGGGTTAGAGAAATCCCTTATTTCATGTCT TGACTCTAAAATTATCAAAGTACTTTTCCTTGTAATGTGGATTTCTTCTTATGCGGATAT GCAAAAACTTCAGTTATACGTAGTAATGCTAGCAGGTAATTTTAGTAGACATTTTATAAC AACTGTCACTTTGTTTCGCCACATGTAGAGTTTGTTCAGCTATTTTCCAGATATCTCCCC ACAAAAGGAGGCAAAGGGTACCAGCTTTTCAATGAGCATTACCTATTACTTGGCAAAGAT GATGAAGACTCTATTAATAGTTCATTTGATAAATGTTGACATAACCAACAATAGAGATTA GGAAGTTAGTTTTAAGAAATCAATGGCATATAGACATTACCCTCATGGAGTTTGTATTCT ACTACTTGAACTGATTGTAGCTATAAAAGCATAGTTAGATAGCTGAATAGTTAGATCATA AGCAAAGAAGGCCAGAACACATCTCTTATCAAGAAATCAATGAATAGTTTATCTCATTTT TAAAGCAACTTTATCCTTCTTTAATTCCTTCCTTTCTTCTAGTGCAAAACTACTTAATAA GGTTGGTGTTTAGGTTAGTGTTCACACCATTCCTCATCTGGTGTGAATTACCTTCTCTTT CTTTACTATTTACTACCAACCTAGTACATGTGTTGACTGAATTCTTTTCAAACAATGTTG AGTTATCATGGTGCACCTAATAAATTAACACCACAGATTACAGCATCCTTGCTGATTTTC TCAGCAAAGCCAGATTAGATGGAAATAAACAAAGAAAATGATCCTAGAGTGAATTTTTCT AGAAAATATCTATTATGAACCATGCTGTTTAAAGTATTAGCTTGAAGGTGATGGATCCAG CTATTCAGAAAATAACTTTCATATAACCATGATTTTGCACAGTATGAGGTCTTAAATGTG TGGAAAGAGATAAATTTTTTATCATTACCACAAACCCCTTTTAAAGATTCAAAGGTGGAA GAAAGTGATTTATTTTTTCTCTTCAGCATACATATATAAAAGACTTGTCAGATGTTTAAT TTGGGGAGGTTGATAATGAAACATATCAACAGAGTATAGTAGTTATAGTAGTGTTTGTGG GTAAATAATTTCCTGGGGTCAGACATATATAAACATATTTGCTTCAAAATGATAAAGGCA TGAAATCAGTCTTAAAAATTGAAATGGGGGTGATGGGGGAGAAAAAGAAGAACAAATTTG AAGTGCCCTTTCAAATCTGCTGGATACAAGTATTGAAGTTTTAAGTCATCTTATTCTGTC TGAAAGTGTATTTTTCATTCTACAATAGACCCAATCAACAAGACGTATAACTTGAGTTGC ATGATGTTCAGTTTATGTAATCTACTGTTGGGATGGTAAGAATTGATGTAGGCTGTGGTG TAAGAATGAATTAAAATATAGTTTCACTGGCTTTTCTCTACATATCCACTATCACAATGG CTAGGTTTCCTGTTGCTCACTATTGGATTCTGGAGAAAAATTTAATGAAAGATGATATCA GAGGAAGAATAAGTGGAGGTAGAGAAGAAAGGAATGATAGAGGAGGGGAAAAAAACAAAA CATATTTTTGTGTTATCCAAAGGAGCTTTTTCCTTATTCTGTCAAGCATTGAGATCTTCT TCAGCTTTCAATGTAGTTGCTAAATACAAATAATGCTACTAGGTAGTGACTAAATATAGC AAACACTTCATCAGATATTAGAATTAGGTCACACTATTGAGGTTATAATCTGAAGGTTGT GTTACATAGAAACCACTTTAGATTATTATCAACTTGGACTAGGCTTTATTTTATAATAGC ATAGTAAGTAATATCTATTGTGTCATTTCTTCAACCATTTTATTCTAAGATCCATGAAGC TTCTTGAGGCCAAATAAAATAATAAGTTTAGACAAGAAGTAGATTGTGACTTTTTTCCCT TAGAGATACTATTTACTATCTCCTATCCTGATAGGTGGAAGGTTTACTGAATTGGAAATT GGTTGACTATTAGTTTTTAACTAAAATGTGCAATAACACATTGCAGTTTCCTCAAACTAG TTTCCTATGATCATTAAACTCATTCTCAGGGTTAAGAAAGGAATGTAAATTTCTGCCTCA ATTTGTACTTCATCAATAAGTTTTTGAAGAGTGCAGATTTTTAGTCAGGTCTTAAAAATA AACTCACAAATCTGGATGCATTTCTAAATTCTGCAAATGTTTCCTGGGGTGACTTAACAA GGAATAATCCCACAATATACCTAGCTACCTAATACATGGAGCTGGGGCTCAACCCACTGT TTTTAAGGATTTGCGCTTACTTGTGGCTGAGGAAAAATAAGTAGTTCGAGGAAGTAGTTT TTAAATGTGAGCTTATAGATAGAAACAGAATATCAACTTAATTATGAAATTGTTAGAACC TGTTCTCTTGTATCTGAATCTGATTGCAATTACTATTGTACTGATAGACTCCAGCCATTG CAAGTCTCAGATATCTTAGCTGTGTAGTGATTCTTGAAATTCTTTTTAAGAAAAATTGAG TAGAAAGAAATAAACCCTTTGTAAATGAGGCTTGGCTTTTGTGAAAGATCATCCGCAGGC TATGTTAAAAGGATTTTAGCTCACTAAAAGTGTAATAATGGAAATGTGGAAAATATCGTA GGTAAAGGAAACTACCTCATGCTCTGAAGGTTTTGTAGAAGCACAATTAAACATCTAAAA TGGCTTTGTTACACCAGAGCCATCTGGTGTGAAGAACTCTATATTTGTATGTTGAGAGGG CATGGAATAATTGTATTTTGCTGGCAATAGACACATTCTTTATTATTTGCAGATTCCTCA TCAAATCTGTAATTATGCACAGTTTCTGTTATCAATAAAACAAAAGAATCCTGTTTGTGT GGTTTCATGAAATCAGCATTGTTGAATGCATGAAGTAATAATGCTAAATTAACATTTTTA TGATGTCTCAAGGTTTCTGGTCAAGGGAAGTAAATGTAGGATAGTATTTTTACACCAAAA TGACACAGAGAGAATTGAGCACACCAGAAAGACCAGAAACCACACCACTGGATAGAGATT CAATATGTTTCTTTTTCAAACATTTGGACAAGAAAAAAATGGGCATTTAAAAATTCTTCC TTCCCCTGGTTATGGATTTATCTGTAGTAAAACTTAGCTTTGTCGTTTGAGATTTGCACA GAATGGGGGGAGTAGATTACCTCTTCCCATTCATTGTCATAATGGATCTACATCACTGAT AAACACCATACTTCTATATGTGGTTAACTAGCTTTAGAATAAAAGACACTTTAAAAAGTA AAAGGCCTAGAGATCTTCAATGAAGTGTCCCTTTTAGCCAAACCAGGCCTTGCAGAAATT GTCCTCAAAAGCACCAAGGGAGAACAAAGCCAAGTGCAGAATTACCCAAGGGTCACACAT TTTGTATTCATTTTCTTATAATTTGCCCAAATGATTTGAAGTACAGCAAAACCTGAAGTT TTGCAAAGAGTTACTGTAAACTGAACTTAAAAATGTCAGAGTGCTCGGTGACCCACTTCT CCAGACCCTGTCAACCTGTGAAAATATTGGCCTTTATTCAGATCTCTCAAGAAGTTACGC GCAGAGTTTGGAAGGTCTAGGCAAAGGTTATTAGTCAAGTGTTCTTACAGTGTCAACGCT CAATTCCCACAAGCGTGAGAAAGAGAGACCTGTCATTCCTGAGGGTGATGACATACATTT ACTGGAGCTTATATAATTTATCAGATAAGACAGCAGTTTCCTTCAGGGTAGAAAGTGTGT TTTCTACATTGATTTAGTACAAAACAAAAAGAAAAGGGGATATTTCAAATTTTATAATTA TTTTTCTGCTAAGCTGATTCAGTGTGATTTAAGCATATTTTTCAAATCATGAATCTGATT CCATATACATATGTGCCTTATATTGTGATAATTTATTTTTAAGTGAAATATGCTATCATA GCCTGACTTTATGTATAGTGGTGACAACTTGCAGGATCGCATTTCTGTAACCAAACGGCC GACAGCTGAGGTGTAGATGCTTCCTATGGTCTGTAGAATAATCACTGGGCTTGTTCTCTA GCTATGTCTGTATGCAATCGCGACAGTGTTGATCAAAACCCATGATCATTCTCTCCAAAG GTCTTTGTCACTAAGCCACTAGGGATTCTGAAAAGTTCGTGAGCTGAAACAAATAAATTG AGTTGGAAGATTAAAAAAAAAA |
Protein Sequence | >586 : length: 398 MASPLRSAAALARQDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLV FGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKI RLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIG TEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYG SSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPG VTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGE TIHIPTMENGPKLASRILSKLTDIQYGREESDWTIVLS |