| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 55742 |
Name | PARVA |
Synonym | CH-ILKBP|MXRA2;parvin, alpha;PARVA;parvin, alpha |
Definition | actopaxin|alpha-parvin|calponin-like integrin-linked kinase-binding protein|matrix-remodeling-associated protein 2 |
Position | 11p15.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Regulation of cytoskeletal remodeling and cell spreading by IPP complex components;PID Reactome;500125 |
Pathway | Cell-extracellular matrix interactions;PID Reactome;500123 |
Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Localization of the PINCH-ILK-PARVIN complex to focal adhesions;PID Reactome;500124 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Disease | Mortality among heart failure patients;NHGRI |
External Links | |
Links to Entrez Gene | 55742 |
Links to all GeneRIF Items | 55742 |
Links to iHOP | 55742 |
Sequence Information | |
Nucleotide Sequence | >55742 : length: 8719 AGCGAGGGAGGGAGCGAGGGAAGGGAAAGGCGAGCGTGAGCTGCCTCAAATGCTTGGAAT AATTCCGCTTCCGTTTGGAAAGCCGCAGCCTCAGTCCCGCCGCCGCCCGCTGCGTCCGCC CAGCGCCAGCTCCGCGTCCCGACCGGCCCGCGGCAGCCTGCGCCGCGCCATGGCCACCTC CCCGCAGAAGTCGCCTTCTGTCCCCAAGTCTCCCACTCCCAAGTCGCCCCCGTCCCGCAA GAAAGATGATTCCTTCTTGGGGAAACTCGGAGGGACCCTGGCCCGGAGGAAGAAAGCCAA GGAGGTGTCCGAGCTGCAGGAGGAGGGAATGAACGCCATCAACCTGCCCCTCAGCCCAAT TCCCTTTGAGCTGGACCCCGAGGACACGATGCTGGAGGAGAATGAGGTGCGAACAATGGT GGATCCAAACTCACGCAGTGACCCCAAGCTTCAAGAACTGATGAAGGTATTAATTGACTG GATTAATGATGTGTTGGTTGGAGAAAGAATCATTGTGAAAGACCTAGCTGAAGATTTGTA TGATGGACAAGTCCTGCAGAAGCTTTTCGAGAAACTGGAGAGTGAGAAGCTAAATGTGGC TGAGGTCACCCAGTCAGAGATTGCTCAGAAGCAAAAACTGCAGACTGTCCTGGAGAAGAT CAATGAAACCCTGAAACTTCCTCCCAGGAGCATCAAGTGGAATGTGGATTCTGTTCATGC CAAGAGCCTGGTGGCCATCTTACACCTGCTCGTTGCTCTGTCTCAGTATTTCCGCGCACC AATTCGACTCCCAGACCATGTTTCCATCCAAGTGGTTGTGGTCCAGAAACGAGAAGGAAT CCTCCAGTCTCGGCAAATCCAAGAGGAAATAACTGGTAACACAGAGGCTCTTTCCGGGAG GCATGAACGTGATGCCTTTGACACCTTGTTCGACCATGCCCCAGACAAGCTGAATGTGGT GAAAAAGACACTCATCACTTTCGTGAACAAGCACCTGAATAAACTGAACCTGGAGGTCAC AGAACTGGAAACCCAGTTTGCAGATGGGGTGTACCTGGTGCTGCTCATGGGGCTCCTGGA GGGCTACTTTGTGCCCCTGCACAGCTTCTTCCTGACCCCGGACAGCTTTGAACAGAAGGT CTTGAATGTCTCCTTTGCCTTTGAGCTCATGCAAGATGGAGGGTTGGAAAAGCCAAAACC GCGGCCAGAAGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCT CTTCACCAAGTACCGTAACGTGGAGTGAGGGGCTGCCCTGGGCCCACCACTGCCCAAGAG TTCTTGCTGTTGGCGTACTGGACCCTCCTCCGAACTGCCTTACCCTGCTTATTCCTGTCT CTTGCACTGTGCTCTCCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAAATTA GGAAGGAAATCATCAATAACTCAGTGGGCTGACCCATCCCTCCCAGGCGCTGGGGACCAA CCTAGCAATGAAGGTTGGGAAGGTTGTTCCCTTCCCGGTGCCAGGTCCAGATTTCCCTCC ATGATTTGGGAACCAGCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCCTAGT TACCATTCAAAGGATGCTAACTGTGTGTCAGGCCCCACACTAAGTGCTCTGCTCTGATAT ACTCAAGGCCATTAATCTTCAGGACTCCCATTGACGTAGGTGTTTCATTCCCCTTTTACA GATGAGGAAACTAAGGCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTTCCTC TTTGAACATAACCTCTCCCTTCTCCCTAAAGGTAACCACTATTCTGAGTCCAATCATCAA GGTTTTGCTTTTCTTTTTAGCTAAGTATGCATTCCTCAATAGTAGACAGTACAACATGTT TATAACAAGCCAATTACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGTGCAC ATCTGAGCACGTGCACATGTACACCTGAGCCAAAAACACGAGAACCCACTGATCTCACCA CTGGGGCAAGCTAGGTCAGAGCTTAGTGATTCACACTGAAATTGGCAAATTGGATTTAAC CCAATTAATAGTGTGTGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAATGAAA ATTACTCTTAATTCCTTCAGATTTATAATAACTCTGTACTTTGGTTTCAGGGTGACATTT GGGAAGGATTTTGTTTAGAATTAATGGAGTGGCACATTTTGCAGCCTTTTTGCTTGATTG CATGTAATGGAAATGCCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCGTTAA GCAAATGTACAATATGCTCAGGCACCGCAGAGAGCTGGGCACGGGCCCATGTGAGCATCA CTTTGGAAGTAGGGCTCTTCAACAGGGACCCTTGAACTTTAAAGAAAGGAACTTCTTTTT GCCTTCTAATTGATCATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACCGGCT AATTCAAGCGAGGAAAAATGTAAGTCATTTAGACCAAAGCCAAGCAGTTTCTTTGCGTGG GTTACTCAAGGGCTTGTGGTTACTTGTATCTCCTCTATGTGAACTTGACTTTGAAAGACA GAGCTCTAGTGTGCCAGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGGGTGG GCAGTGACTAGGGGACGAGAAGCATGGGGAAAATATTTGCACTCTAAACATACAGAGATA GAGGTGGGGCTTGTGGTACTTAACACTTGTAGCCATCAACTGACTGAGACCTTGGGCTAA ATAATCAATTGTGCTGATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGGTAGA CACCAGCCCAAGTACCCTCCTCCAGAAGTCTGTGACTACCTTGTCACTACTTTAGGCCCA TTCCACAAAGCCCATCTCTGGTTTGAGAATTCATTTTGATCTGTATCTACACCACCCAAA GTTAGGCCTCCTATAATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGTACTG TCTCTTACTGTACTGTCTATCTGCAGTAATTGAGGACCCATAAAATTTAGATAACTACAT GTCTTTGCTCTTAGAATTGTCACTCAGCATAATGAGCATTTAACATACAAAGGCAATGTA CTGTTTTGTGTTGATCTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAAATTT TATTTTTTATTAGGAAACACTAAATAGTGTAATATTTCTTTTGCTTTTAAAAAAATTCCT GGTAGCAAATCAAGATAAATAATTGCTTCATTTTCTTGAGCAATACTGAAGCAGGATGAA GTAAGAGGAATGCATTCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTTTGGT CTCTTTTTCTTATATTCAAGTTACAAATGTACAAGTATCCTTACTAAGAGTGCTCCTTTT GTATTTTACATATATACAGTATGAAAATACATTGGAACACTAGGAAAGTTTTTAAATAAC AGTTCTAATTTATCAGAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAGAATC CCAGGTCCTGGGCCTGGTTTTCTAATGCTGTCATCTCAGTTCGATATTTTACTTTAGAAC CTGGAATCTCCTACTTAATATATGACCATGACTTTGAAAGGCAAAAGAGGAATCAAGAAT AAATAAAACAAACTTAATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGAGAAT CAACACTTCATAGGCTCACTGGGTTTTCTTTTCTTTTCTGTTAATTTAAACTCAGTTATT TTTAATGCTTAATACATACATGGTGCAAAATTTAAAAAGCGCAAATAGGTATCTAGTGGA AAACCTAAGCCTCCCTCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTGTTTT GATCCATTTCTTACACACACTGCCAGAGATACTCTAGGCATGTAAAGCACAAACATACAT ATAAAATCTGCGGGCTTCAAAAAATATAAGTAGGATGTCATCTATACTGTCATACACTTT GTTTTTTATCACTTAATGTTATATCTTGGATATTGTATTACCCTGGGTATTAAAAAGAAC TCCTTTCACATTTTAAAATAACAATCTGAGCACTTCATAAATCCAAATGCGTATCTCCAG TCTGCTCGAGCTAGGAAAGGAAAAAAGCCCTAGCCGAAGGAGGAAAGGCTGCCTAGACAA TGATTTCAAAAGTAGAGTCTAAAACCTATGGGGTGCAGGACCAGAGGCTGGGGCACATTA TCAGAGGCATCCTCATGTGCCTCGAACCGAATGTTTTTAAGTCCTCTTTTGGAACCTTAT GGTGAATTGTATGCAGATTGATGAAGGTTTCATTTTTATATATTACCAGGACTACGAATT TGTAATCCACTAAGCATCACAAAGGTTACTACATACGCTATAATACTGTACTATAAAGTC TAGCTGCCAGCAATGCAGTGCTCGCCTGCTATATTAGAAGGCTCCAGTTTCACATGTGCA GGCACAGAGATGACATTTCCCGATCTGGGAGAAGGCTTCTTTATCAGCACATCATCAGTG TTGCCTCGAGTTGGTTGCAATTTTCAATTGCTGCTATTGGTGCTTTTTAATTATGAATTA CTGTTAGCTTGCATTATCATCAGTTTGTTTTGTTGTGGGTTGCTTGGTTAACCCTACAGA GTATACTTGAAGCTTATTTGCATCAACAGTATTCTGGAGCTGTAATTTTTCAATAACTAG ACTCTGAGACATGTATACATTGTGGTTCAAATAGGAATCATCCATAGTCCAGTGCTAGAA CAAATGTATACATAATCCACTCCCCACAAATTATCACTCATTTATTTTTCCACTGGAAAA TAAGACTAGATGGAGTCGGTAGGTGAAACAGTTTTGCCGTGCCTAAGTGGAGGCTGATCA AAACTAATTTGAGATCCGCTGCCTTTAATAGAGCTCCACCTCAGGAATCTTACCTTTATA ATACATCCTAGATAGGCAAGAGGGATATGTCCTGAAATCTTCACTAATTCCAAGATTGCG TGTCATTTCCCCCAAAAATTTGCTTAACTCTATTGGAAAATCCAAGAGAATTGCTGCAGC TGCTGAAAACAAGAGAGCTGCATTAAGCTGCAAGGCCGGGTAGGGTAGGTAGACTGACTC ACCACCTATGGGACCTGCCTCCACACATCAGCTTCCCAAATACTTGCAGATTTGGGTCTT ACCAAAAGAAAAGTCAGTATGAGTTACTCACAATCCTAACTACAAAGGCTACATTTACAA ATACCAGAGTTTCGACTGTGTTTTTACTCTCTGCTCCCTGAAAACTGTAACCCCAGGCTA GCTCCAAACTCTGCTTATAGCCCATGCTTTACTACAGTGGTGGTCGCATATGTGAACGTG TGCATGCGTGTTCACGTGTTCATGACAACAGCAATGCAGCCATGAGGGTGCTGCCCCCAA ACCAAGCCTGATGACCTTGAGAACCTCAGGCTTCCCAGTAGGATCCTGCAAGAAAGCATC TCTTAAAAATAAATTCTACAGGATATTAGTAAATGTTAGATGAAAAAAAAAGTCACGTTT AAATATGTTTAGGAAACATGAGGTGAAGAAAGTTAGCTTACTGACGCTTTTTGTTTTCTA GTTGGAGCGCACCTCAGAGTCCCCTACATAATGCGTATTAGGACTTTCTAAGGGAAGACG GGGTACGATGGGTCCCAATCTTGTTTGATCACAGGATGTATCTGTCCCCTGAGAAATTTC TAGGATGAGTACTCTGAACTCAGGACTTCATTTAGTCATATATTCGGCAAGTATGTGTTG AGTGCAGCATGTCCAAGGGTGAGTGAGAGATTATAGCTAGCAGGGGAGACAGATGAAAAA TAACTATGAATCGACGTTAGTTACAAATTGTGACTGTCGCGATGGAGAAGTACTAAAATC TATGAAAGAGTTCTAATGTAGATTTAAGGTCATGAGAAGTCTCCGGCAAAGTGGCATTTT AAAGTAATCCCTCAGTCGTGGAGCTACTCCAATGAGAAGCCTGCCACTCCAGGGCGCACC ACGGAGGAGGATCCCCAGACAAGAAGACCTGGCTCCCCAGAGGAGTGCGGAAAGCCAGCA TGGCTAGAGGACACAGAATGAGGGAGAAGACGGATCCGATCGCAGGCATCGGGAGTGCTG ATTTTTCTCCTTTGAAAAACAGGTTGCCATCTACCTTTTTAAATGTCCCACTGTGTAGGA AAACTCTGGGGAAAGCTACGTCAGCAATATGGAGTCTGGGGTTGCCTTTCTCATGTCATA CCATGGTCCTGGCTGGGGAGCGGAGGAGACCAGGAGAGGAGATCAGACCTCTGCCCACCC CAACACCAATCTGGTCTTAGCAACCTCTGGGCATCCCATAGCTCCTCCTAACCTGCTGCT GCTGATGGACAGGAACTCCTGGACTACCCCCAGCCTCTCCACAATGTGTCCTGAGAAGAG CTAGGGGAACTGGACAGAGTGGACGAGGCTGCATGTGTGGAGGGAATGAAATAAGGGGCC TACCAGGCCAGAACGCTGATCCATGGAGACCAGTGCTTCCAGCCCTCTCACCTCGGAGGA GGACTCCTGTTTTACCAACGGCAGGAGCAGGAATCCCACCATTCAGCCTGTGGGCTTGAC AAACTATAAGCAAGCCTCCTGGATGTGGAATAATACATTTTCAAAATTCATACTAATCAG CATGAACTATAACTGCTCCAATGCCCACCACATTATATAAAATCTACCAAAAGGGGGTCA CTTAATGTTTCACAATGTTTGGTGAAACAACTTTCATATGAAAGTACGGTTGATCCTTGA ATGATATGGGCACCGACCCCTGAGCAGCTGAAAATTTGCATGTAACTTGACTCCCCCAAA ACGTAACTATAATACTAATAGCCTTACTGAACACGGTCAATTAACACATAGCTAGTATGT TATGTGCATTATATACTATATCCTTACCATACGGTAAGCTAGAGAAAAAATGTTACTAAG AAAAACATAAGCAAGAGAAAATATATTTACTATTAAGTGAAAGCAGGTCATCATAAAGTC CTCATCCTCATGGTCATCACATTGAGTAGGCGGAGGAGGAGGAGGAGGAGGAGGAGTAGG GGTTGGTCTTGCTGTCTGAGGGGTGGCAGAGGCAGAAAAAAAATCCATGGGCCGAGCACG GTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGACAGATCACAAGGTCA GGAGATTGAGACTATCCTGGCTAATATGGTGAAACCCCGTCTGTACTAAAAATACAAAAA ATTAGCCAGGTGTGGTGGTGCGTGCCTGTAATCCCAGCTACTCAGGGGGCTGAGGCAGAA GTATTGCTTGAACCCAGGAGGCAGAGGTTGCAATGAGCTGAGATCGCATCACTGCACTCA AGCCTGGGCAACAGAGCAAGACTGCGTCTCAAAAAAACAAAACAAAACAAAACAAAAATC CATGAACAAGTGGACCTGCCCAGTTCAAATCATTGTTGTTCAAGGGTCAATTGTATATTA TTTTCACTGGAAGTTTTGAAATTCCAGAAATATGCTTGGAAATCCCCGCTTGAAATCTCC TTGGTTGGAAACCAGTCCAGTGGGTGACTGGCCCAGAATGATGCTTCTCCTCGGTGGACC CCCTGGGCTGAGCAGCCTGTGTTCCTGCCTCAACTCCCCTGAACCCTCCTGAACTTTCTA CACACATGTGGGCACTGGCTTTGATACTGGCATTTGGAAGGGCACTTGGGAAATTCAGAG AAGTACCCATTATTAAGATAAATGATGTTTTATCAATGAAGCAGACTTTTCATTTCTTTT TATTGATCTTCATGTTTTCACATCTTGAGATGCAATTTGTTAGCACAGGCTGTCATTCCA AGACACACAAATGTCATTAAGGCAACCGCTTAAAGGAGTGTGATATTTTATTGAGGTAGA CAGGACAATAGATAAATATTTAATCTGTTACATGTTTGCTCTGTGTGGAGCCAGGGTTGG GGCTGCACAACTCTCTGGCTGCTATGTGTCTTCCTGGAAACCCTGTCAAAGGCCTTACCG CCTGCCTGGAGAAACACAGTGCCTGCCCTTGGCAAATATATGTTGGTGTATCTGAAAAAC AGCTCCTGGAAGCTTTTTCTCATTCAGGCTTTAGGGGTTACCCCATCTTTCCTTATGTGT GTAATATTGGAGAATGTACACTCTCACTGAACTGGGGATGTTTGACTTAAAATGATGGAC AATAAGATAGTGAGCAGTAAGTGTGCTCTAGGCTAGGCTACGAGAGGCCATGAGCTCCTC ATCTCTTCTCTGTTCTGAGCTCTCTGATCCACTGCACTTGGGGCAGGGGGTGCATTCTCT GTGCCTCTCCTGAGTCTACTTTCTGCATCATTGGTTCTCCCAGCTCACTTCCATAATGTC CTCCTAGGCTGCATTGGAATTGTGTGTTGTCTAGACCCATGGCCAAGACTGTCATTGCCT GTGAGGGAGACCAAGCTCACCACCAAGGGCTTTTGCCAGATTGCTTTCATTTACAGAATT TGCCCATTCATGTGTCTTTGTGTTTATGGATTAAATGGCTTTCTGACCAGCATCCCTTTG GTGTGCTTTGTCAATAAGA |
Protein Sequence | >55742 : length: 412 MLGIIPLPFGKPQPQSRRRPLRPPSASSASRPARGSLRRAMATSPQKSPSVPKSPTPKSP PSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEV RTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEK LNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQY FRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDK LNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSF EQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE |