| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5530 |
Name | PPP3CA |
Synonym | CALN|CALNA|CALNA1|CCN1|CNA1|PPP2B;protein phosphatase 3, catalytic subunit, alpha isozyme;PPP3CA;protein phosphatase 3, catalytic subunit, alpha isozyme |
Definition | CAM-PRP catalytic subunit|calcineurin A alpha|calmodulin-dependent calcineurin A subunit alpha isoform|protein phosphatase 2B, catalytic subunit, alpha isoform|protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform|serine/threonine-protein |
Position | 4q24 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | signaling pathway from g-protein families;PID BioCarta;100153 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | effects of calcineurin in keratinocyte differentiation;PID BioCarta;100222 |
Pathway | Alzheimer's disease;KEGG PATHWAY;hsa05010 |
Pathway | role of mef2d in t-cell apoptosis;PID BioCarta;100109 |
Pathway | t cell receptor signaling pathway;PID BioCarta;100022 |
Pathway | regulation of pgc-1a;PID BioCarta;100075 |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Opioid Signalling;Reactome;REACT:15295 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Amyotrophic lateral sclerosis (ALS);KEGG PATHWAY;hsa05014 |
Pathway | nitric oxide signaling pathway;PID BioCarta;100092 |
Pathway | VEGF signaling pathway;KEGG PATHWAY;hsa04370 |
Pathway | B cell activation;PANTHER;P00010 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | bcr signaling pathway;PID BioCarta;100227 |
Pathway | fmlp induced chemokine gene expression in hmc-1 cells;PID BioCarta;100162 |
Pathway | nfat and hypertrophy of the heart ;PID BioCarta;100098 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Pathway | regulation of ck1/cdk5 by type 1 glutamate receptors;PID BioCarta;100201 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | endocytotic role of ndk phosphins and dynamin;PID BioCarta;100099 |
Pathway | Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650 |
External Links | |
Links to Entrez Gene | 5530 |
Links to all GeneRIF Items | 5530 |
Links to iHOP | 5530 |
Sequence Information | |
Nucleotide Sequence | >5530 : length: 4676 AGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGG CGGCCGCGGCACCAGCGGCGGCGCTCTGTGTGGAGAAGCAGGGGCAGCGGCAGCAGCAAC AGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCCGGGGACGCC AAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCT TCCCCATGTGATCGGTCTTAATCCTGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGG TGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCCATCCCCCTT CCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCAC ACACGCGCAGCCCGGAGCGAGTCGGCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGG CGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAGCTCAGAGCC TAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGT GTCTGGCCCGCCGGTCCGGTCGGGGTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTC CTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGAC AGGGTGGTGAAAGCTGTTCCATTTCCTCCAAGTCACCGGCTTACAGCAAAAGAAGTGTTT GATAATGATGGAAAACCTCGTGTGGATATCTTAAAGGCGCATCTTATGAAGGAGGGAAGG CTGGAAGAGAGTGTTGCATTGAGAATAATAACAGAGGGTGCATCAATTCTTCGACAGGAA AAAAATTTGCTGGATATTGATGCGCCAGTCACTGTTTGTGGGGACATTCATGGACAATTC TTTGATTTGATGAAGCTCTTTGAAGTCGGGGGATCTCCTGCCAACACTCGCTACCTCTTC TTAGGGGACTATGTTGACAGAGGGTACTTCAGTATTGAATGTGTGCTGTATTTGTGGGCC TTGAAAATTCTCTACCCCAAAACACTGTTTTTACTTCGTGGAAATCATGAATGTAGACAT CTAACAGAGTATTTCACATTTAAACAAGAATGTAAAATAAAGTATTCAGAACGCGTATAT GATGCCTGTATGGATGCCTTTGACTGCCTTCCCCTGGCTGCCCTGATGAACCAACAGTTC CTGTGTGTGCATGGTGGTTTGTCTCCAGAGATTAACACTTTAGATGATATCAGAAAATTA GACCGATTCAAAGAACCACCTGCATATGGACCTATGTGTGATATCCTGTGGTCAGACCCC CTGGAAGATTTTGGAAATGAGAAGACTCAGGAACATTTCACTCACAACACAGTCAGGGGG TGTTCATACTTCTACAGTTACCCGGCTGTATGTGAATTCTTACAGCACAATAACTTGTTA TCTATACTCCGAGCCCACGAAGCCCAAGATGCAGGGTACCGCATGTACAGGAAAAGCCAA ACAACAGGCTTCCCTTCTCTAATTACAATTTTTTCAGCACCAAATTACTTAGATGTATAC AATAACAAAGCTGCAGTATTGAAGTATGAGAACAATGTTATGAATATCAGGCAATTCAAC TGTTCTCCTCATCCATACTGGCTTCCAAATTTCATGGATGTTTTTACTTGGTCCCTTCCA TTTGTTGGGGAAAAAGTGACTGAGATGCTGGTAAATGTCCTCAACATCTGCTCAGATGAT GAACTAGGGTCAGAAGAAGATGGATTTGATGGTGCAACAGCTGCAGCCCGGAAAGAGGTG ATAAGGAACAAGATCCGAGCAATAGGCAAAATGGCCAGAGTGTTCTCAGTGCTCAGAGAA GAGAGTGAGAGTGTGCTGACGCTGAAAGGCTTGACCCCAACTGGCATGCTCCCCAGCGGA GTACTTTCTGGAGGGAAGCAAACCCTGCAAAGCGCTACTGTTGAGGCTATTGAGGCTGAT GAAGCTATCAAAGGATTTTCACCACAACATAAGATCACTAGCTTCGAGGAAGCCAAGGGC TTAGACCGAATTAATGAGAGGATGCCGCCTCGCAGAGATGCCATGCCCTCTGACGCCAAC CTTAACTCCATCAACAAGGCTCTCACCTCAGAGACTAACGGCACGGACAGCAATGGCAGT AATAGCAGCAATATTCAGTGACCACTTCCTGTTCACTTTTTTTTTTTTTTTTTTTTTTTT TTTTTGAGCTGCGGGGCATGATGGGGATTGCTGCATATCAGCAGTTGGATGTTCTTGCCT CTGACAGTAGCTTATTTGCTCTGGGGGCCAGGAATTGGATTCAGTTTACACTATCATTAA AAAAGAGGGAGAGAGATAATAAACTATATTTTGGTGGGGATGGTGATTAAACACCTCTTT TGGGTATGCCTTTTAAAAATGCTTATAGAGAAAAAAAATTTTAAAAAGAAAGCTAATGCT AGTATATACTGCAATGTTAGGGGAATGAACATGTTTTCCTACTGCATTGGGGACTTCTAG ATAGGTTAATGAAAGGCCTTTTATTCTGTTACTGGACATGAAAACTTTGTCTAATTTCTT ACTCTATTGTACGTTTACAGTCGCAGCACTAAAAATGGATGACATCAAACATTTTTAACA AAATGATGTACAAACTAAGGACTATTTATTGATAATGTTTTGCTACTCTTGTCAGACAAT GGCTATAAACTGAATTAGGCAGTCTTAAAAAAAAAAAAAAACAGAAAAAGAAAAAAAAGA ACGTTGCAAATTTGTTAAAATGCCAAAAAGGACAGTTTAATTTTGTACAGATTATGCTTA CCTCAGGTTTCTTTAGTGTGCTTGAATGCCCTTCTTTCCATATAACACTTATCTTCTTCT TAATTCGGCAATGGAATATCTTTTAAGTTTTAAAAAAACTGGAATAATTATATCTATCTT TTTTGCCGTTTATATTTAGGGGTTTTTGTTGATAAAATCAAGTCTTGGTTGTGGCTTGCT GAATTAAATATTTATGAGTGGTGCATTTTTAAGTATAGTGAACAAGACACCATATTAAGT ACAGTGATAAAGCATCTATATTCTGTAAAAAAAAAAAAAATCTGCCTATGCATGTTTTTT AAGAAAAAAAAAATGGCTGTATCGGCCTGTATGGGACTGTAATGCGCTTAGTGGTCTGAC ATATACTGGAAATGTATGTATACTGGCGTACTTTATATTCTCTAAAATGCTTAATGCCTT TGAAATTTTGTAATCAAAAAAAAGCTTTGAAAAAATCTAAAGGGGAGAGTATTCTTTAAA GTTTTTAACATAAGCTTGTCAATGCACATGTAGATGGTTAGCATGTTTAGCAAACCTTGT GAAATTATAATAAGTTTGTAGTTACATGTGAAACTCTAAATGCATGGCAACTGTTAATGT CATAACAGTTTAGTTATTTTGTTCTGTTCTGTCATGTGCCACAAAATATGTACTTTTTTC ACTTTTTTCCCTTTGTATATCAGTTACGGGTTACAACTGGTTCATTCTGAAAACAACAAC AACAAAAGTCCATTCATATTTTTTAACAATTGTATAAGTGCCCAAGTAATTCACTACAGC CTAAAGCCTTGCCTTTGTAATTTGACTTCTGACATGTTGGCAATCAAAGCATGCACTTGT AACAATGAAAAAGAAAAAGCATTTTATATTACTACTCAATAAAATGTGCATGAACTTACA GAATTCTCATCCTTCCACTGAGTCCGCTGAAGGGATTTATGTGCACAACCACCATGTGTC TTCTAGGTGCTGGCCCACCACCACACATCACAGGCTGATTTCCACAGGCTTCTTCCTAGG GGCCTCGTGATCTGAGGGGTGGTGCCTACTTCCACTGTAAGAAAGAATCTTGGTGGATTT GTGTCTCAAATCAGATAAGAGAAGCCTGTTTAAAGAGCAGATGCCATCTTCTGGCTTCCT CAAGGAGCCAGTTAAAAAACCAGAGCATTCCTTTTTATTGAAAAATAAAATTAATTTGTT ATCAGGTTGTTTCAGTTGTATTGGATGCCCTATCTATCTGCTAAAGCAAAAAGTACTAGG CTACTAAGTGCATTTTCATCACAGAAAAGAGTTGCATTTGTATTAACAAGAAATTTGTAT ACCCACGCTTCAGCTACTATCTAATCATCACCCGAAGATTTAAGATACACCAAATTTCAG TTTGTTTGTAACATTGTTCATCTTTAGTGCACTTTGTTTTATATAATAAAGTATGCCTGT TATATTAAATAATAAGAATATGGCAATTAGCGATATAGCATACCCAAACAAAGATGTTCT CGATACAGTCTGGCAAAGACTATCCCAAGGTTATTTTAATGAATTCAGACATTTTTTCCT GTGGATATTTCTCCATCCTAAAAAAAGTGGCAACCAAGGAAAATATTTAGATGCAACTTA CTAGAGTGATGATGTGAAAGAAATGGTGATTCTGGTATCATGGTGTTTATTTTCTTTCTT ATAACTGCAGAGAAAATATCCTGACTAAAAAAAATTCATTTTTTTGGATTCCTTTCTTTT ACAAATTGTGCTGAGGCAACTATGGCATAGAAATAAACATTTGACATTAAAATAAG |
Protein Sequence | >5530 : length: 521 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ |