| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 55294 |
Name | FBXW7 |
Synonym | AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4;F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase;FBXW7;F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
Definition | F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)|F-box protein FBW7|F-box protein FBX30|F-box protein SEL-10|F-box/WD repeat-containing protein 7|archipelago|homolog of C elegans sel-10 |
Position | 4q31.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Notch signaling pathway;PANTHER;P00045 |
Pathway | Metabolism of proteins;Reactome;REACT:17015 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | C-MYC pathway;PID Curated;200093 |
External Links | |
Links to Entrez Gene | 55294 |
Links to all GeneRIF Items | 55294 |
Links to iHOP | 55294 |
Sequence Information | |
Nucleotide Sequence | >55294 : length: 5100 TCTGGAGTGAGGCGAGAGCCCCGCACAGAGCGAGGGAGACAGCGAGCTGAGCTCCGGGCG CTGCCGCTGCCGCTGCCGCCGCCGCCGCCGCTGAGACTGAGAGCGAAGGAGCATCCGAGA GATCCAGTCCCCCTGCACTGGCCGCCGCCGAGACCTTCGCTCTCACCTGGGCCAGCGGGA GCCGCGGCCGCACTCCTTTCCCCCCCTCACCTTCCCGGCCGGCAGCGGCGGCTGCACACG CCGGAGCCGGAGCCAGAGCCGGAGCCCGAGCCTGAGCCGGAGCCGGCGGCTTGGGGGGCA GGGAGGCGGCTACCACGGGCCGGGAGTGGGTAGCTGCTCCGCGGTGAGAGAACGCTGAGG AGGCGCCAGAGCTTCTGCCTCGTCCCGTGGGGCGTGGGGCGAGACCCCCAAGGTGTAGGG AGGGGGGTCCCAGCCGCAGCGACACATGCGGGAGCCGGGAGCGGGGGCGGCGCCGAGCGG AGCCGGCCGGGTCCCTCGCCTTGCCGCCGACTCGGCCACCCGCCCGGGGCCGTAGCATCT TGCCCCGGAGTGTATGAACCGGGGCCCCAACCAAGCTCGGCAACCACCCCCCGGCCGGGG GGGCGGGGACCCCGATGTGAAGCGGCGGCTGGGGCGGCGGAGAGAACAGGACCGACGCCG CCGTCCTTTCCTCACCTTCCCCCTCCCCTCAGCCCCCTCCGGGGGTCTTCTCCCTTGGCC AGTCGCCGGCCCCCCGGCTCCTTGGCTGGACTCCGGGAGGAGTTCCTAGAGCCCCCCTCC CCCGCCCCAGTCCCGAGGGCGGCGGGGCCGGGGGGGACCCGGGGGGCCGGCCGCAGCCTC CACCCAGAGGAAACTTTACAAAAACAAAATCCGGAGTCTCCCAAACCTGACTGTCCCGGG AGAAGTGGCCCTGGACGGGCAGAAGCCGCAGCCTGAAAAGACCCAGGAAGAGGAAAAGAG GAGTACCGCGCCGGAGCCTTCCGCAGCTGCCGCTTCAGTCCGAAGGAGGAAGGGAACCAA CCCACTTTCTCGGCGCCGCGGCTCTTTTCTAAAAGTGATTACTTCCTTAGGATAGATTGC CAGAAGTGGAGTTACTGGGTCAGAGGAATGTGAAAACCTTTGCATCTTCTGATAGTCTAG CCAAGGTCCAAGAAGTAGCAAGCTGGCTTTTGGAAATGAATCAGGAACTGCTCTCTGTGG GCAGCAAAAGACGACGAACTGGAGGCTCTCTGAGAGGTAACCCTTCCTCAAGCCAGGTAG ATGAAGAACAGATGAATCGTGTGGTAGAGGAGGAACAGCAACAGCAACTCAGACAACAAG AGGAGGAGCACACTGCAAGGAATGGTGAAGTTGTTGGAGTAGAACCTAGACCTGGAGGCC AAAATGATTCCCAGCAAGGACAGTTGGAAGAAAACAATAATAGATTTATTTCGGTAGATG AGGACTCCTCAGGAAACCAAGAAGAACAAGAGGAAGATGAAGAACATGCTGGTGAACAAG ATGAGGAGGATGAGGAGGAGGAGGAGATGGACCAGGAGAGTGACGATTTTGATCAGTCTG ATGATAGTAGCAGAGAAGATGAACATACACATACTAACAGTGTCACGAACTCCAGTAGTA TTGTGGACCTGCCCGTTCACCAACTCTCCTCCCCATTCTATACAAAAACAACAAAAAGAG TATTCGTCAACCAAGAGGAGTTTTAAAATGTCAAAACCGGGAAAACCTACTCTAAACCAT GGCTTGGTTCCTGTTGATCTTAAAAGTGCAAAAGAGCCTCTACCACATCAAACTGTGATG AAGATATTTAGCATTAGCATCATTGCCCAAGGCCTCCCTTTTTGTCGAAGACGGATGAAA AGAAAGTTGGACCATGGTTCTGAGGTCCGCTCTTTTTCTTTGGGAAAGAAACCATGCAAA GTCTCAGAATATACAAGTACCACTGGGCTTGTACCATGTTCAGCAACACCAACAACTTTT GGGGACCTCAGAGCAGCCAATGGCCAAGGGCAACAACGACGCCGAATTACATCTGTCCAG CCACCTACAGGCCTCCAGGAATGGCTAAAAATGTTTCAGAGCTGGAGTGGACCAGAGAAA TTGCTTGCTTTAGATGAACTCATTGATAGTTGTGAACCAACACAAGTAAAACATATGATG CAAGTGATAGAACCCCAGTTTCAACGAGACTTCATTTCATTGCTCCCTAAAGAGTTGGCA CTCTATGTGCTTTCATTCCTGGAACCCAAAGACCTGCTACAAGCAGCTCAGACATGTCGC TACTGGAGAATTTTGGCTGAAGACAACCTTCTCTGGAGAGAGAAATGCAAAGAAGAGGGG ATTGATGAACCATTGCACATCAAGAGAAGAAAAGTAATAAAACCAGGTTTCATACACAGT CCATGGAAAAGTGCATACATCAGACAGCACAGAATTGATACTAACTGGAGGCGAGGAGAA CTCAAATCTCCTAAGGTGCTGAAAGGACATGATGATCATGTGATCACATGCTTACAGTTT TGTGGTAACCGAATAGTTAGTGGTTCTGATGACAACACTTTAAAAGTTTGGTCAGCAGTC ACAGGCAAATGTCTGAGAACATTAGTGGGACATACAGGTGGAGTATGGTCATCACAAATG AGAGACAACATCATCATTAGTGGATCTACAGATCGGACACTCAAAGTGTGGAATGCAGAG ACTGGAGAATGTATACACACCTTATATGGGCATACTTCCACTGTGCGTTGTATGCATCTT CATGAAAAAAGAGTTGTTAGCGGTTCTCGAGATGCCACTCTTAGGGTTTGGGATATTGAG ACAGGCCAGTGTTTACATGTTTTGATGGGTCATGTTGCAGCAGTCCGCTGTGTTCAATAT GATGGCAGGAGGGTTGTTAGTGGAGCATATGATTTTATGGTAAAGGTGTGGGATCCAGAG ACTGAAACCTGTCTACACACGTTGCAGGGGCATACTAATAGAGTCTATTCATTACAGTTT GATGGTATCCATGTGGTGAGTGGATCTCTTGATACATCAATCCGTGTTTGGGATGTGGAG ACAGGGAATTGCATTCACACGTTAACAGGGCACCAGTCGTTAACAAGTGGAATGGAACTC AAAGACAATATTCTTGTCTCTGGGAATGCAGATTCTACAGTTAAAATCTGGGATATCAAA ACAGGACAGTGTTTACAAACATTGCAAGGTCCCAACAAGCATCAGAGTGCTGTGACCTGT TTACAGTTCAACAAGAACTTTGTAATTACCAGCTCAGATGATGGAACTGTAAAACTATGG GACTTGAAAACGGGTGAATTTATTCGAAACCTAGTCACATTGGAGAGTGGGGGGAGTGGG GGAGTTGTGTGGCGGATCAGAGCCTCAAACACAAAGCTGGTGTGTGCAGTTGGGAGTCGG AATGGGACTGAAGAAACCAAGCTGCTGGTGCTGGACTTTGATGTGGACATGAAGTGAAGA GCAGAAAAGATGAATTTGTCCAATTGTGTAGACGATATACTCCCTGCCCTTCCCCCTGCA AAAAGAAAAAAAGAAAAGAAAAAGAAAAAAATCCCTTGTTCTCAGTGGTGCAGGATGTTG GCTTGGGGCAACAGATTGAAAAGACCTACAGACTAAGAAGGAAAAGAAGAAGAGATGACA AACCATAACTGACAAGAGAGGCGTCTGCTGTCTCATCACATAAAAGGCTTCACTTTTGAC TGAGGGCAGCTTTGCAAAATGAGACTTTCTAAATCAAACCAGGTGCAATTATTTCTTTAT TTTCTTCTCCAGTGGTCATTGGGCAGTGTTAATGCTGAAACATCATTACAGATTCTGCTA GCCTGTTCTTTTACCACTGACAGCTAGACACCTAGAAAGGAACTGCAATAATATCAAAAC AAGTACTGGTTGACTTTCTAATTAGAGAGCATCTGCAACAAAAAGTCATTTTTCTGGAGT GGAAAAGCTTAAAAAAATTACTGTGAATTGTTTTTGTACAGTTATCATGAAAAGCTTTTT TTTTTTTTTTTTTGCCAACCATTGCCAATGTCAATCAATCACAGTATTAGCCTCTGTTAA TCTATTTACTGTTGCTTCCATATACATTCTTCAATGCATATGTTGCTCAAAGGTGGCAAG TTGTCCTGGGTTCTGTGAGTCCTGAGATGGATTTAATTCTTGATGCTGGTGCTAGAAGTA GGTCTTCAAATATGGGATTGTTGTCCCAACCCTGTACTGTACTCCCAGTGGCCAAACTTA TTTATGCTGCTAAATGAAAGAAAGAAAAAAGCAAATTATTTTTTTTTATTTTTTTTCTGC TGTGACGTTTTAGTCCCAGACTGAATTCCAAATTTGCTCTAGTTTGGTTATGGAAAAAAG ACTTTTTGCCACTGAAACTTGAGCCATCTGTGCCTCTAAGAGGCTGAGAATGGAAGAGTT TCAGATAATAAAGAGTGAAGTTTGCCTGCAAGTAAAGAATTGAGAGTGTGTGCAAAGCTT ATTTTCTTTTATCTGGGCAAAAATTAAAACACATTCCTTGGAACAGAGCTATTACTTGCC TGTTCTGTGGAGAAACTTTTCTTTTTGAGGGCTGTGGTGAATGGATGAACGTACATCGTA AAACTGACAAAATATTTTAAAAATATATAAAACACAAAATTAAAATAAAGTTGCTGGTCA GTCTTAGTGTTTTACAGTATTTGGGAAAACAACTGTTACAGTTTTATTGCTCTGAGTAAC TGACAAAGCAGAAACTATTCAGTTTTTGTAGTAAAGGCGTCACATGCAAACAAACAAAAT GAATGAAACAGTCAAATGGTTTGCCTCATTCTCCAAGAGCCACAACTCAAGCTGAACTGT GAAAGTGGTTTAACACTGTATCCTAGGCGATCTTTTTTCCTCCTTCTGTTTATTTTTTTG TTTGTTTTATTTATAGTCTGATTTAAAACAATCAGATTCAAGTTGGTTAATTTTAGTTAT GTAACAACCTGACATGATGGAGGAAAACAACCTTTAAAGGGATTGTGTCTATGGTTTGAT TCACTTAGAAATTTTATTTTCTTATAACTTAAGTGCAATAAAATGTGTTTTTTCATGTTA |
Protein Sequence | >55294 : length: 707 MNQELLSVGSKRRRTGGSLRGNPSSSQVDEEQMNRVVEEEQQQQLRQQEEEHTARNGEVV GVEPRPGGQNDSQQGQLEENNNRFISVDEDSSGNQEEQEEDEEHAGEQDEEDEEEEEMDQ ESDDFDQSDDSSREDEHTHTNSVTNSSSIVDLPVHQLSSPFYTKTTKMKRKLDHGSEVRS FSLGKKPCKVSEYTSTTGLVPCSATPTTFGDLRAANGQGQQRRRITSVQPPTGLQEWLKM FQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKD LLQAAQTCRYWRILAEDNLLWREKCKEEGIDEPLHIKRRKVIKPGFIHSPWKSAYIRQHR IDTNWRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH TGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRD ATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGH TNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNAD STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNL VTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK |