| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5337 |
Name | PLD1 |
Synonym | phospholipase D1, phosphatidylcholine-specific;PLD1;phospholipase D1, phosphatidylcholine-specific |
Definition | choline phosphatase 1|phosphatidylcholine-hydrolyzing phospholipase D1|phospholipase D1 |
Position | 3q26 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Pancreatic cancer;KEGG PATHWAY;hsa05212 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | metabolism of anandamide an endogenous cannabinoid;PID BioCarta;100217 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | phospholipases;BioCyc;LIPASYN-PWY |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Alpha-synuclein signaling;PID Curated;200187 |
Pathway | Glycerophospholipid metabolism;KEGG PATHWAY;hsa00564 |
Pathway | rac1 cell motility signaling pathway;PID BioCarta;100056 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | Ether lipid metabolism;KEGG PATHWAY;hsa00565 |
Pathway | choline biosynthesis III;BioCyc;PWY-3561 |
Pathway | Ras Pathway;PANTHER;P04393 |
Pathway | GnRH signaling pathway;KEGG PATHWAY;hsa04912 |
Pathway | ras signaling pathway;PID BioCarta;100047 |
Pathway | CDC42 signaling events;PID Curated;200057 |
Disease | Brain tumor;FunDO |
Disease | Melanoma;FunDO |
Disease | Breast cancer;FunDO |
External Links | |
Links to Entrez Gene | 5337 |
Links to all GeneRIF Items | 5337 |
Links to iHOP | 5337 |
Sequence Information | |
Nucleotide Sequence | >5337 : length: 6025 CCCTCCCTCCCGCTGAGCTCCAGCTGTGCCAGAGGCACCCGAGCCCTGAGAGTCCGCCGC CAACGCGCAGGTGCTAGCGGCCCCTTCGCCCTGCAGCCCCTTTGCTTTTACTCTGTCCAA AGTTAACATGTCACTGAAAAACGAGCCACGGGTAAATACCTCTGCACTGCAGAAAATTGC TGCTGACATGAGTAATATCATAGAAAATCTGGACACGCGGGAACTCCACTTTGAGGGAGA GGAGGTAGACTACGACGTGTCTCCCAGCGATCCCAAGATACAAGAAGTGTATATCCCTTT CTCTGCTATTTATAACACTCAAGGATTTAAGGAGCCTAATATACAGACGTATCTCTCCGG CTGTCCAATAAAAGCACAAGTTCTGGAAGTGGAACGCTTCACATCTACAACAAGGGTACC AAGTATTAATCTTTACACTATTGAATTAACACATGGGGAATTTAAATGGCAAGTTAAGAG GAAATTCAAGCATTTTCAAGAATTTCACAGAGAGCTGCTCAAGTACAAAGCCTTTATCCG CATCCCCATTCCCACTAGAAGACACACGTTTAGGAGGCAAAACGTCAGAGAGGAGCCTCG AGAGATGCCCAGTTTGCCCCGTTCATCTGAAAACATGATAAGAGAAGAACAATTCCTTGG TAGAAGAAAACAACTGGAAGATTACTTGACAAAGATACTAAAAATGCCCATGTATAGAAA CTATCATGCCACAACAGAGTTTCTTGATATAAGCCAGCTGTCTTTCATCCATGATTTGGG ACCAAAGGGCATAGAAGGTATGATAATGAAAAGATCTGGAGGACACAGAATACCAGGCTT GAATTGCTGTGGTCAGGGAAGAGCCTGCTACAGATGGTCAAAAAGATGGTTAATAGTGAA AGATTCCTTTTTATTGTATATGAAACCAGACAGCGGTGCCATTGCCTTCGTCCTGCTGGT AGACAAAGAATTCAAAATTAAGGTGGGGAAGAAGGAGACAGAAACGAAATATGGAATCCG AATTGATAATCTTTCAAGGACACTTATTTTAAAATGCAACAGCTATAGACATGCTCGGTG GTGGGGAGGGGCTATAGAAGAATTCATCCAGAAACATGGCACCAACTTTCTCAAAGATCA TCGATTTGGGTCATATGCTGCTATCCAAGAGAATGCTTTAGCTAAATGGTATGTTAATGC CAAAGGATATTTTGAAGATGTGGCAAATGCAATGGAAGAGGCAAATGAAGAGATTTTTAT CACAGACTGGTGGCTGAGTCCAGAAATCTTCCTGAAACGCCCAGTGGTTGAGGGAAATCG TTGGAGGTTGGACTGCATTCTTAAACGAAAAGCACAACAAGGAGTGAGGATCTTCATAAT GCTCTACAAAGAGGTGGAACTCGCTCTTGGCATCAATAGTGAATACACCAAGAGGACTTT GATGCGTCTACATCCCAACATAAAGGTGATGAGACACCCGGATCATGTGTCATCCACCGT CTATTTGTGGGCTCACCATGAGAAGCTTGTCATCATTGACCAATCGGTGGCCTTTGTGGG AGGGATTGACCTGGCCTATGGAAGGTGGGACGACAATGAGCACAGACTCACAGACGTGGG CAGTGTGAAGCGGGTCACTTCAGGACCGTCTCTGGGTTCCCTCCCACCTGCCGCAATGGA GTCTATGGAATCCTTAAGACTCAAAGATAAAAATGAGCCTGTTCAAAACCTACCCATCCA GAAGAGTATTGATGATGTGGATTCAAAACTGAAAGGAATAGGAAAGCCAAGAAAGTTCTC CAAATTTAGTCTCTACAAGCAGCTCCACAGGCACCACCTGCACGACGCAGATAGCATCAG CAGCATTGACAGCACCTCCAGTTATTTTAATCACTATAGAAGTCATCACAATTTAATCCA TGGTTTAAAACCCCACTTCAAACTCTTTCACCCGTCCAGTGAGTCTGAGCAAGGACTCAC TAGACCTCATGCTGATACCGGGTCCATCCGTAGTTTACAGACAGGTGTGGGAGAGCTGCA TGGGGAAACCAGATTCTGGCATGGAAAGGACTACTGCAATTTCGTCTTCAAAGACTGGGT TCAACTTGATAAACCTTTTGCTGATTTCATTGACAGGTACTCCACGCCCCGGATGCCCTG GCATGACATTGCCTCTGCAGTCCACGGGAAGGCGGCTCGTGATGTGGCACGTCACTTCAT CCAGCGCTGGAACTTCACAAAAATTATGAAATCAAAATATCGGTCCCTTTCTTATCCTTT TCTGCTTCCAAAGTCTCAAACAACAGCCCATGAGTTGAGATATCAAGTGCCTGGGTCTGT CCATGCTAACGTACAGTTGCTCCGCTCTGCTGCTGATTGGTCTGCTGGTATAAAGTACCA TGAAGAGTCCATCCACGCCGCTTACGTCCATGTGATAGAGAACAGCAGGCACTATATCTA TATCGAAAACCAGTTTTTCATAAGCTGTGCTGATGACAAAGTTGTGTTCAACAAGATAGG CGATGCCATTGCCCAGAGGATCCTGAAAGCTCACAGGGAAAACCAGAAATACCGGGTATA TGTCGTGATACCACTTCTGCCAGGGTTCGAAGGAGACATTTCAACCGGCGGAGGAAATGC TCTACAGGCAATCATGCACTTCAACTACAGAACCATGTGCAGAGGAGAAAATTCCATCCT TGGACAGTTAAAAGCAGAGCTTGGTAATCAGTGGATAAATTACATATCATTCTGTGGTCT TAGAACACATGCAGAGCTCGAAGGAAACCTAGTAACTGAGCTTATCTATGTCCACAGCAA GTTGTTAATTGCTGATGATAACACTGTTATTATTGGCTCTGCCAACATAAATGACCGCAG CATGCTGGGAAAGCGTGACAGTGAAATGGCTGTCATTGTGCAAGATACAGAGACTGTTCC TTCAGTAATGGATGGAAAAGAGTACCAAGCTGGCCGGTTTGCCCGAGGACTTCGGCTACA GTGCTTTAGGGTTGTCCTTGGCTATCTTGATGACCCAAGTGAGGACATTCAGGATCCAGT GAGTGACAAATTCTTCAAGGAGGTGTGGGTTTCAACAGCAGCTCGAAATGCTACAATTTA TGACAAGGTTTTCCGGTGCCTTCCCAATGATGAAGTACACAATTTAATTCAGCTGAGAGA CTTTATAAACAAGCCCGTATTAGCTAAGGAAGATCCCATTCGAGCTGAGGAGGAACTGAA GAAGATCCGTGGATTTTTGGTGCAATTCCCCTTTTATTTCTTGTCTGAAGAAAGCCTACT GCCTTCTGTTGGGACCAAAGAGGCCATAGTGCCCATGGAGGTTTGGACTTAAGAGATATT CATTGGCAGCTCAAAGACTTCCACCCTGGAGACCACACTGCACACAGTGACTTCCTGGGG ATGTCATAGCCAAAGCCAGGCCTGACGCATTCTCGTATCCAACCCAAGGACCTTTTGGAA TGACTGGGGAGGGCTGCAGTCACATTGATGTAAGGACTGTAAACATCAGCAAGACTTTAT AATTCCTTCTGCCTAACTTGTAAAAAGGGGGCTGCATTCTTGTTGGTAGCATGTACTCTG TTGAGTAAAACACATATTCAAATTCCGTATACCAAAATCCATTTCCTTTGTAACAAGAAT TTACCAGTAACTGTGATCTAGGTTGCCAAAAGTTGTCTGAATCTCCTTATTCTTCTCTGA TCTTCATTTATGCAGCCAATGTCTAGCTGGACCTGCCCTCATCTTGCAGTTCATACAGGC ACTGTTTGAGAGATTGTTTATTATTAGATGTTGTAATGCTGCTTCAAGATTCTTCATGGT TACATGGGATGCCCCTGCTCATCTGGTCCTGAAGTAGTAACATTCACCCAAATGAGGATA TAGTCATTATTCCTTTTCAGTCACTGTACGAACACGGCAGACTTTAGCCTACACAGTAGA CTGTGTTAGGCACTTCTGGTAACATTGACACTGTATCTTGACACCACTAAGCAACAGGAA GGAATAAATTCCAATATTGAGACAGAGATTTATTTCATTTTGCTCCCAAAGGCACTGACA ACATGAGTCCTTGTGATTAGGCCCACCTGATCAAATGTAAAAACATGCATGGGATATTTG ATTACGTAACAACCAGCTAAAACTGAGAGCACACAGCCTTCGGAAACCCCCAAGGTGTCG AGGAGGATCAGATCCAGATAAGAGAAGATGATTCCTTCTAGTCCTGTAAAATTTCCTGTC ATCCTTAGCTGCTGGGTTGATTGAAATTTGATCTCTACATTTCAAAATCAAACTAGTGAA TACAGTTTGTCTTTCAAGAGAATCAGAGGCATCGTAACTCCTACCAAGTTAGTAAGTATG AGTCTAACCTTGTTTGACATTCAGGTCTTCTGCTACATTATCTTCTTTGAGAAAAATTAA TTGATTATAAAATATGTGCTACTTCACTTACATTATTAAATATGTATTAACGCCTCTCAC CAGGGCTTCCAGTGAAGTTACAATGCCCTAGTCTGTGAATTAGTCTGGAAACGTGTTTTT CCTTTTCGGATGTTAGAGTACCCTTTGATAAACTAAATTTTACTAAGCTGAACAACTCTG ACAGTCTAAAGAGCTAATGTGGGTTACCAAAAGGCCTGTACCTGTAAAACAAAATGCAGG TGTAATGATTATACATGTCTATGGATTACCTGGACATACTCTCATTTGGGTTGTTCTTCA AAGAAGCAAGCAGCCGATCCCTGTTTTCATAAAGCTAATACTTCAGTTGGAAAAATTAAA CAGGAGCACAAAGTCAGGGATAGGGGTTAGCAGAAGAGAGAAATAGTGTCACATCAAGGG CAGGATCTCATAGCTAGGGAACATTTCACAAATAAGGTGAGATTTTGTAACCAATAATAA AAATGAATGTTTTTATAAGTAAATAACTTATTTTTCATATGGCTAAAGATGGTAAAATGA CTTCATTCTATAGCCATTGTAAATAAGAATTTGCTATTGATGAAAGAAGTTCAGATTGGC ATTTGAAGTATTGAGTGTATGGGATCTCTAAGGATTTCTTAGATTTTATATTTAAATATT TTTTAAACCTTAGAGGAGTCAACAAACTGGCTCTTGATTTTCAGCACCCTACTCTCATGA AAAAAGCCTGAAAGGACCCTTTCCCTTATAAGTAATTTAATCCAATTTCTCCCCATTTTA TAGATGAGGAAACTGAGGCTCAGATCAGATGAGAACTCACTTAAATCCACTCAATGTGTA GATGGTAGAGCTGGGACTAGCAACATTGCTGCAGCCCATTGTTGGCCTCTCTCTTCACTT TATCATTGCCCAAGAATGAGGATATGCAGTAAACAGAATTCAGGCAAGATACCTCTAAGC TGTTTTGAACCCTCTGATATTTTGTATTTATGTGTTTGTCTGTCTCCCCCTACTAGAATG TAAGCTCCATGGGGCAGGGACTTCACTGTATTTTGTTCATAGTGTATCCCCAGAGCCTGG ACCAGTGCTTGGCACATAGGAGATGGCAATAAATGCTTGTAGAATTAATAAACAAGGTGA AGGAGAGAGCTAATGAAATGAAAATCTTAGTCTCATATAAGAAGTCTTACTACTGCTTTC TATGGCAAGTTCCTTTTCTATTGCATCTTCCCAAAGACAAGATGCTCATCTGCAAAGGGG TGATAAGATTTACTTGGAGGGATTTTATGGAAAATTCAGTGCAATAATTGCTTTTTTTTT TTTTTTTGCAGTAGCAGTTTACATAGTACAGCATTCTGCAAAAATTGCATGAAATGTGGA CACAAGATGTACTGTATGACTTAATTACCTGTCATTCTCTGACACCATTACTACCTACTA GAAGTTCAAATAATTTATCTTTAACATTGCAATATCTGATAAACTTTTTAAAATGTAAAT AATTCAAAGCCTTGAAAATCTATCATGAATCTGCTCAACATTTCAAAGTGACTATTTTGA AATGCCTATAAATGCTATATACCTG |
Protein Sequence | >5337 : length: 1074 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT |