| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5167 |
Name | ENPP1 |
Synonym | ARHR2|COLED|M6S1|NPP1|NPPS|PC-1|PCA1|PDNP1;ectonucleotide pyrophosphatase/phosphodiesterase 1;ENPP1;ectonucleotide pyrophosphatase/phosphodiesterase 1 |
Definition | E-NPP 1|Ly-41 antigen|alkaline phosphodiesterase 1|ectonucleotide pyrophosphatase/phosphodiesterase family member 1|membrane component chromosome 6 surface marker 1|membrane component, chromosome 6, surface marker 1|phosphodiesterase I/nucleotide pyrophos |
Position | 6q22-q23 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Nicotinate and nicotinamide metabolism;KEGG PATHWAY;hsa00760 |
Pathway | Pantothenate and CoA biosynthesis;KEGG PATHWAY;hsa00770 |
Pathway | Starch and sucrose metabolism;KEGG PATHWAY;hsa00500 |
Pathway | Purine metabolism;KEGG PATHWAY;hsa00230 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Metabolism of vitamins and cofactors;Reactome;REACT:11193 |
Pathway | Vitamin B2 (riboflavin) metabolism;PID Reactome;500885 |
Pathway | Riboflavin metabolism;KEGG PATHWAY;hsa00740 |
Pathway | regulators of bone mineralization;PID BioCarta;100089 |
Disease | lipids;GAD |
Disease | Obesity, susceptibility to;OMIM |
Disease | PC-1 protein content;GAD |
Disease | obesity;GAD |
Disease | Diabetes;KEGG DISEASE |
Disease | ossification of the posterior longitudinal ligament of the spine;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | nephropathy in other diseases;GAD |
Disease | glucose;GAD |
Disease | osteoarthritis;GAD |
Disease | Hypophosphatemic rickets, autosomal recessive, 2;OMIM |
Disease | METABOLIC;GAD |
Disease | Diabetes mellitus, non-insulin-dependent, susceptibility to;OMIM |
Disease | Insulin Resistance;GAD |
Disease | diabetes, type 2;GAD |
Disease | Type II diabetes mellitus;KEGG DISEASE;H00409 |
Disease | CARDIOVASCULAR;GAD |
Disease | insulin;GAD |
Disease | Ossification of posterior longitudinal ligament of spine;OMIM |
Disease | insulin left ventricular mass;GAD |
Disease | lipoprotein;GAD |
Disease | systolic blood pressure;GAD |
Disease | nephropathy, diabetic;GAD |
Disease | Metabolic diseases;KEGG DISEASE |
Disease | cholesterol;GAD |
Disease | body mass;GAD |
Disease | Arterial calcification, generalized, of infancy;OMIM |
Disease | metabolic syndrome;GAD |
Disease | ossification of the posterior longitudinal ligament of the spine (OPLL);GAD |
Disease | glucose insulin obesity;GAD |
Disease | RENAL;GAD |
External Links | |
Links to Entrez Gene | 5167 |
Links to all GeneRIF Items | 5167 |
Links to iHOP | 5167 |
Sequence Information | |
Nucleotide Sequence | >5167 : length: 7442 CCGGAGCGGCCGGGGCCACGATGGAGCGCGACGGCTGCGCGGGGGGCGGGAGCCGCGGCG GCGAGGGCGGGCGCGCTCCCCGGGAGGGCCCGGCGGGGAACGGCCGCGATCGGGGCCGCA GCCACGCTGCCGAGGCGCCCGGGGACCCGCAGGCGGCCGCGTCCTTGCTGGCCCCTATGG ACGTGGGGGAGGAGCCGCTGGAGAAGGCGGCGCGCGCCCGCACTGCCAAGGACCCCAACA CCTATAAAGTACTCTCGCTGGTATTGTCAGTATGTGTGTTAACAACAATACTTGGTTGTA TATTTGGGTTGAAACCAAGCTGTGCCAAAGAAGTTAAAAGTTGCAAAGGTCGCTGTTTCG AGAGAACATTTGGGAACTGTCGCTGTGATGCTGCCTGTGTTGAGCTTGGAAACTGCTGTT TAGATTACCAGGAGACGTGCATAGAACCAGAACATATATGGACTTGCAACAAATTCAGGT GTGGTGAGAAAAGGTTGACCAGAAGCCTCTGTGCCTGTTCAGATGACTGCAAGGACAAGG GCGACTGCTGCATCAACTACAGTTCTGTGTGTCAAGGTGAGAAAAGTTGGGTAGAAGAAC CATGTGAGAGCATTAATGAGCCACAGTGCCCAGCAGGGTTTGAAACGCCTCCTACCCTCT TATTTTCTTTGGATGGATTCAGGGCAGAATATTTACACACTTGGGGTGGACTTCTTCCTG TTATTAGCAAACTAAAAAAATGTGGAACATATACTAAAAACATGAGACCGGTATATCCAA CAAAAACTTTCCCCAATCACTACAGCATTGTCACCGGATTGTATCCAGAATCTCATGGCA TAATCGACAATAAAATGTATGATCCCAAAATGAATGCTTCCTTTTCACTTAAAAGTAAAG AGAAATTTAATCCTGAGTGGTACAAAGGAGAACCAATTTGGGTCACAGCTAAGTATCAAG GCCTCAAGTCTGGCACATTTTTCTGGCCAGGATCAGATGTGGAAATTAACGGAATTTTCC CAGACATCTATAAAATGTATAATGGTTCAGTACCATTTGAAGAAAGGATTTTAGCTGTTC TTCAGTGGCTACAGCTTCCTAAAGATGAAAGACCACACTTTTACACTCTGTATTTAGAAG AACCAGATTCTTCAGGTCATTCATATGGACCAGTCAGCAGTGAAGTCATCAAAGCCTTGC AGAGGGTTGATGGTATGGTTGGTATGCTGATGGATGGTCTGAAAGAGCTGAACTTGCACA GATGCCTGAACCTCATCCTTATTTCAGATCATGGCATGGAACAAGGCAGTTGTAAGAAAT ACATATATCTGAATAAATATTTGGGGGATGTTAAAAATATTAAAGTTATCTATGGACCTG CAGCTCGATTGAGACCCTCTGATGTCCCAGATAAATACTATTCATTTAACTATGAAGGCA TTGCCCGAAATCTTTCTTGCCGGGAACCAAACCAGCACTTCAAACCTTACCTGAAACATT TCTTACCTAAGCGTTTGCACTTTGCTAAGAGTGATAGAATTGAGCCCTTGACATTCTATT TGGACCCTCAGTGGCAACTTGCATTGAATCCCTCAGAAAGGAAATATTGTGGAAGTGGAT TTCATGGCTCTGACAATGTATTTTCAAATATGCAAGCCCTCTTTGTTGGCTATGGACCTG GATTCAAGCATGGCATTGAGGCTGACACCTTTGAAAACATTGAAGTCTATAACTTAATGT GTGATTTACTGAATTTGACACCGGCTCCTAATAACGGAACTCATGGAAGTCTTAACCACC TTCTAAAGAATCCTGTTTATACGCCAAAGCATCCCAAAGAAGTGCACCCCCTGGTACAGT GCCCCTTCACAAGAAACCCCAGAGATAACCTTGGCTGCTCATGTAACCCTTCGATTTTGC CGATTGAGGATTTTCAAACACAGTTCAATCTGACTGTGGCAGAAGAGAAGATTATTAAGC ATGAAACTTTACCCTATGGAAGACCTAGAGTTCTCCAGAAGGAAAACACCATCTGTCTTC TTTCCCAGCACCAGTTTATGAGTGGATACAGCCAAGACATCTTAATGCCCCTTTGGACAT CCTATACCGTGGACAGAAATGACAGTTTCTCTACGGAAGACTTCTCCAACTGTCTGTACC AGGACTTTAGAATTCCTCTTAGTCCTGTCCATAAATGTTCATTTTATAAAAATAACACCA AAGTGAGTTACGGGTTCCTCTCCCCACCACAACTAAATAAAAATTCAAGTGGAATATATT CTGAAGCTTTGCTTACTACAAATATAGTGCCAATGTACCAGAGTTTTCAAGTTATATGGC GCTACTTTCATGACACCCTACTGCGAAAGTATGCTGAAGAAAGAAATGGTGTCAATGTCG TCAGTGGTCCTGTGTTTGACTTTGATTATGATGGACGTTGTGATTCCTTAGAGAATCTGA GGCAAAAAAGAAGAGTCATCCGTAACCAAGAAATTTTGATTCCAACTCACTTCTTTATTG TGCTAACAAGCTGTAAAGATACATCTCAGACGCCTTTGCACTGTGAAAACCTAGACACCT TAGCTTTCATTTTGCCTCACAGGACTGATAACAGCGAGAGCTGTGTGCATGGGAAGCATG ACTCCTCATGGGTTGAAGAATTGTTAATGTTACACAGAGCACGGATCACAGATGTTGAGC ACATCACTGGACTCAGCTTCTATCAACAAAGAAAAGAGCCAGTTTCAGACATTTTAAAGT TGAAAACACATTTGCCAACCTTTAGCCAAGAAGACTGATATGTTTTTTATCCCCAAACAC CATGAATCTTTTTGAGAGAACCTTATATTTTATATAGTCCTCTAGCTACACTATTGCATT GTTCAGAAACTGTCGACCAGAGTTAGAACGGAGCCCTCGGTGATGCGGACATCTCAGGGA AACTTGCGTACTCAGCACAGCAGTGGAGAGTGTTCCTGTTGAATCTTGCACATATTTGAA TGTGTAAGCATTGTATACATTGATCAAGTTCGGGGGAATAAAGACAGACCACACCTAAAA CTGCCTTTCTGCTTCTCTTAAAGGAGAAGTAGCTGTGAACATTGTCTGGATACCAGATAT TTGAATCTTTCTTACTATTGGTAATAAACCTTGATGGCATTGGGCAAACAGTAGACTTAT AGTAGGGTTGGGGTAGCCCATGTTATGTGACTATCTTTATGAGAATTTTAAAGTGGTTCT GGATATCTTTTAACTTGGAGTTTCATTTCTTTTCATTGTAATCAAAAAAAAAATTAACAG AAGCCAAAATACTTCTGAGACCTTGTTTCAATCTTTGCTGTATATCCCCTCAAAATCCAA GTTATTAATCTTATGTGTTTTCTTTTTAATTTTTTGATTGGATTTCTTTAGATTTAATGG TTCAAATGAGTTCAACTTTGAGGGACGATCTTTGAATATACTTACCTATTATAAAATCTT ACTTTGTATTTGTATTTAAAAAAGAAAAATATTCCTATCCTGCTCACTGGTAATTAACAT AGGTTTAAAATGGCTTCAAATGTGGCCCTATAGACGGTTAAAATTGTACCTTATCTTGGC AAAACTTCAGAGCACCAGTCAGTGCATGCAAGGTGCCATTTTTTATTGAGATGCTTAGAA TGTTTCTTTCTGTGCACAAGACTTACCCTACCAGCAGCAGAGCCATTCTCTGTTGAGTGG TTCATTTTGAAGTTCCACAGATTGAAGAGAACATGCCACCAATCACCTCACATCTTCTTG GTGGACATGATAAATGACACAATGAACTTGATTTCTTTACTACCTTGACTGTAGCTTTTT ATCCCTACCTGTGAACCTTCAAAGACTGCATTAACTTTTAGGCTACATAGGTCCAATTGA GGTATAATATCAGTACACCAAAGATTTTTATATGTCCTTCGTGTGACCATTCTTCAACGG CCTAAGGGCCAGCTGCAAAGACTTTTGGAAAATACAATTTACAACTCAAAATTATTTAAT AATTTAGGAAGTTGCTTTTTTTTTTTTTTTTTTTCAGTCCTGCAGTTTCCTGAAGCTCTG TATATGATATTTTTTTCAGCCTGCTTCTCTCTGTTGTTCAGATTAGGTAATTTTATTCTT CTGTCTCGAAGCTCACTGATTCTTTATTCTGTCTAATCTGTTCTGCTGTTGAGCCCATTT ATTCCTGATTTTTATATTTTAGTTATTGTATGTTTTATTTCTAAAATTTCCATTCAGTTT TTCTTTATATCTTCTATTTGCTGAGAATTTCTGTCTCTTTGCTGAGACTTTCTACGTTTT CATTTGTTTCAAGTGCATTTATACTTGCTTGTTGAAGAATTTTTATGATGGCTGCTGTAA AATCCTTATCAGATAATTCCAACATCTGTCACCTCATTGTTTGCATCTACTGATGGTCTT TTTTCCATTCGGAAACATTTTCCTGTTTCTTGGTGTGTGGAATGATTTTTTATTGAAACC TGGATATTTTTAGGTATTATGTTATGAGACTATGGGTCTTATTTAAACCTTCTGCTTTAG CCAACTTTCTCAGATACCACCACAGCAGGGGAATTGGGAGCACTGCTTCATTATTACCAG GTGTGGCTAGGAGTCCAGGTTCCCCAGTCAGCCTCCCTTTATACTGAGTAACAGGGTCCC CTCATTACTACTGGGCAAGGTGAGAATTCAGTTTCCCATTAGGTCTTTATTGATTCTTCC CTGGCTGGAATGTGCAGCGGCACCTTTTGGTGCACCCTGGGAATCTCCACTAATGCTATG GGACAGAGTGACCAGGAAGAGCTTCATTACACCAGGTGGGAATGAAATTCCCAGTAGCCT ACACAGCCTTCTCCGACACCACTCTGGAGTTGTATTCTTCCAGCACACAAACATACACAA TTTAACTCAAAGCATCTTAGCAGAGCTTAATTAAATGGATAGATGCCTGTTCCCTTTGCT GGATACCAAGAATACAAAAGTCAGGGAGTTGGGGCACCTCTTTACAGCTTGGTGAGAGTG TAAGTCTGGACTCCCCACTCAGCATTTGCTGGTATGGGTGGGGCCATGGTGTTTTTCCAT GGTGTTTGGTTGGAGTACAGCCTTTTTTACCCTTGCTTGGCTACCCTTTTCTGGTCCTTT GGCAGGAGAGAGCAGGACTCTCTTAGGGCTTTTTTTTCCCCTGCATTTATTGACATTTCC AGGTTGCTGACTTTTTCAGCTCCAAGTTGGAAATATATGAGCTGAAAAGAAAATGTAGGG AACTCATCACAGTGTTGTTACTTGGGCCCCAATGTTCCTAGCCTATTTTCTGTCTACTAT TCAGAGTCTTGCTGTGTTTTAATATAATATCCAGGATTTTTATATGCATTTAGCAGAAGG ATGTCTACTCTGCCTTTGTAGAAGTGTCTCACTGATTTTTACATATTTTTCCAGCACACA AACATACACAATTTAACTCAAAGCATCTTAGCAGAGCTTAATTAAATGGATAGATGTCTG TTCCCTTTGCTGGACGCCAAGAATACAAAAAAGAACAAGTGACAATTTTCTCTGTCTTAG GGAGAAGAGACAGCAGAAGTGTAAATGATCCCTAAAGAGTGATAGATGTTATCATGAAGC CACAGGAGGGGTGCCAGGCTGCACAAAAGAGACACTGGATGCTTCTTGGTAGTAGAGGCA GTGGCTTCCCAGCCTTGGGGCTAAGGCTTGTAGGGTGAATTGGAACTTTTCAGATGAGCA AGGCAAAGAAGGGACCTTCTAACATTCCTTGGATGGAACATTTTTGACATTTTCCCATTT ACAGCTACTTATATTTTCTACAAGTGTCACTGTGACCAACTTATGTACACATACTTTTTC TTGCTTAGTTATAATAATCTGTTCTTAAAGAAAATGTCAGTCTCTACATTCTATGCTGAC TGTTAAGGAAAGAGCACCCACATCTGCTCCTACTTAGCTTTTTTTCTGTGGTTCTTACAC AGTATTCCTTTTTTTCTTTTCTTGAAAGAGACTCCTCCTTTCTTTTCTTTTCTTGAAAGA GTTTTAAACAGATAAGATGGCAAAAGTGACTGATCTCTACTCCCCCAGTTTGAATGGTAA ATTTGAATGGTAAATTCCCATGAACATATATGGAAATGTCTTTATCCTACTTTCTCCAAT AAAGGCTGTTCTTAGCTTTTCAAATGCAAAGTGAAACCTTTATTTATCTTGATTTCTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGCTCTGTCACCCAGGCTGGAGTGCAGTGG CAAGATCTTGGCTCACTGCAAGCTCCGCCTCCCAGGTTCACGCCATTCTCCTGGCTCAGC CTCCCGAGTAACTGGGACTACAGGCACCTGCCGTCACGCCTGGCTAATTTTTTGTATTTT TAGTAGAGAATGGAGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTTGTGA TCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCTCGAGCCACTGCCTCCAGCC TATCCTGATTTCTACTGTCATGCCTCACATCAGTCCTTTTTTTTTTTTTTGAGACAGAGT CTCGCTCTGTGGCCCAGGCTAGACTGCAGTGGCATGATCTCGGCTCACTGCAACCTCCAC CTCCGGGGTTCTAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTATAGGCGCA TGCCACACCTGGCTTTTTGTATTTTAGTGGAGATGGGGTTTCACTGTGTTGCTCAGGCTG GTCTTGATCTCCTGAGCTCAGACAATCCCCCCGCCTTGGCCTCCCAAAGTGCTAGGATTA TAGGCGAGAGCTGCTGTGTGCTTCTTAAGTGAGGTAAGTAACTTCCATAGAAAATTTCCA TCAGTTCATTCATGAAAGAACAAAGAACCTGGCAAAACTTAAAAAAACGTTTCCAAGAAT CAGATAAAAGAGGACAAACCTTAGGGAGAAGAAGGCAGCTGCTCATTTCCAGCAGGGGAA GTAGCTGCATAGAGTACAAGGACTGGTAGGCCTGTTGGCTGTTCCTGTTTAAGGAGACAA GATGGGCATGGAACAGGGACCACCCCCTCCTCTGGGAGAAGCTGTTACCCCCTTCACTTT TCCTCCTCTGTCATTACCCACAATCACTCTCCTTCTTTGCGCTATGGTAGGTGTTTACCC ATCATAGGAATGGGCATTTGAACTTTGAAACTGAATGTGGTGATTACACTTCATGCTGAA GCTTTTCACATGAGTGCTTTCATAAGCATTAAGTAAAATTTTATAATGACTGCAGTCCAA GGACATTTTCCCTGGTTTTTGGCCAGTCTAAATATTGTAAGAGAGAGAGAAGAAAAGTGT ACGGAATATAATTGTCTCTAAGCTAAGAAATGTGGATGTTCAAATAAAACATACGTACAG AA |
Protein Sequence | >5167 : length: 925 MERDGCAGGGSRGGEGGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAPMDVGEEPL EKAARARTAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFGNC RCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINY SSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKK CGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEW YKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLP KDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLIL ISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSC REPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNV FSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVY TPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYG RPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPL SPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTL LRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKD TSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSF YQQRKEPVSDILKLKTHLPTFSQED |