| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 50943 |
Name | FOXP3 |
Synonym | AIID|DIETER|IPEX|JM2|PIDX|XPID;forkhead box P3;FOXP3;forkhead box P3 |
Definition | FOXP3delta7|forkhead box protein P3|immune dysregulation, polyendocrinopathy, enteropathy, X-linked|immunodeficiency, polyendocrinopathy, enteropathy, X-linked|scurfin |
Position | Xp11.23 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | IL2 signaling events mediated by STAT5;PID Curated;200158 |
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Disease | Other well-defined immunodeficiency syndromes;KEGG DISEASE;H00107 |
Disease | diabetes, type 1;GAD |
Disease | IMMUNE;GAD |
Disease | Immune system diseases;KEGG DISEASE |
Disease | Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked;OMIM |
Disease | Diabetes mellitus, type I, susceptibility to;OMIM |
Disease | Primary immunodeficiency;KEGG DISEASE |
External Links | |
Links to Entrez Gene | 50943 |
Links to all GeneRIF Items | 50943 |
Links to iHOP | 50943 |
Sequence Information | |
Nucleotide Sequence | >50943 : length: 4136 CAGAGGGCCAATGGGCAGCCATGCACGGATGACGTACAGCGAATTGAGAGCCGGAGAAGC ACGCAGCCAATGGGGATGCCCGGGAGTGGGCGGTGTAGGGGGCGGGATGATCGAGGAATC AATGGAGAGGCCGGAATGGGGGTGGTGCGAAATCCATGATGAAGAAAACAGAAGCAGACA GCTAATGCGGAAGTCTGAGCGAGAGAGGTCTGAAGCCAGTCTTGTAGAGGGCTGGAGTGG TTGTTGGACGACTAGAACCCTGGGCTTTGCAGGGTGCTGGGAGCTGGAAGTCTTCACCAT GGCCTGTCAGGAGAAGCCCCTGGGGGCTGGTCTACCATGCTGACCAGTGGTTGAATAGAG TGCCTGCTGAGGTCAAGAGATGCAGCCGCCAATTCCTGGACAACCTAAAAGCCTCACAAG CTTCAAGTCTCCAAGGACTCTCCAAATCCCAGGATCTCCCTGCCATCACATCCTAGAATT TAAAACCTGAGAACATCAAGTTCAGGAAAGCTTGGGGATTTCAAAGCCCAGCACCAAAGA AAGCGGGACCCACACTCGCCAGCTCTGTGATCTTGGGCAAGTTGCTTGACTACTTATACC TCCGTTTCCCTCATCTGTATAACAGGAATACAATAATGATGAGATGGAGCTCAAGGGGCC ATGGTGAGGATTGAACATGATCACTTGTGAGACATGTTCAGCACTGTATCTGACCCATGG AAAATTCAAGATAAACATCAGCTACTGAGATGATGGCGGATATTTGGAATCCTAAATCCT TGGAAACTGGGGCTTTTTGAAGTAAAAGACCCCAAAGGCTGAGGGCCTCAGAAGCATCAG GCCATGATGTTCCTGAAACAAGAGGGTCAGGGTCCCAATGGGCCTCTGGGGTTCATCGTG AGGATGGATGCATTAATATTGGGGACCTGCTAGGGACCTTCCCAGTGGGACAGTGGCTGG GTCAGGGCACTCAAGCCCTAAAACGTGATGAGGCGAGACTTTTCTCTCTTTCCTCATTCA GTAACTGTCAGTAGATTCTGGGAGCCAGGGATTCTCCGACTCTTCAAGTCCATGAATTTT AGGGGATGACAGTGGGCTCTCCGCTTTCTCCTCCATGAAGTAACTTACATGCCCCTCACC CTCTGTGGGAGGGGTGTTGCAGGGGGTGCAGAACTCCCCTCGCCGGGTAGTTCAAGCAAT GGGGACCATATCAATTCCATCTATAGGGAAACTGAGGCCTGGAGTAGGGCGAGGCCTCTG GGAACCCAGCCCTATTCTGTCTCTTTCCCTGGCATTTCCCATCCACACATAGAGCTTCAG ATTCTCTTTCTTTCCCCAGAGACCCTCAAATATCCTCTCACTCACAGAATGGTGTCTCTG CCTGCCTCGGGTTGGCCCTGTGATTTATTTTAGTTCTTTTCCCTTGTTTTTTTTTTTTCA AACTCTATACACTTTTGTTTTAAAAACTGTGGTTTCTCATGAGCCCTATTATCTCATTGA TACCTCTCACCTCTGTGGTGAGGGGAAGAAATCATATTTTCAGATGACTCGTAAAGGGCA AAGAAAAAAACCCAAAATTTCAAAATTTCCGTTTAAGTCTCATAATCAAGAAAAGGAGAA ACACAGAGAGAGAGAAAAAAAAAACTATGAGAACCCCTCCCCACCCCGTGATTATCAGCG CACACACTCATCGAAAAAAATTTGGATTATTAGAAGAGAGAGGTCTGCGGCTTCCACACC GTACAGCGTGGTTTTTCTTCTCGGTATAAAAGCAAAGTTGTTTTTGATACGTGACAGTTT CCCACAAGCCAGGCTGATCCTTTTCTGTCAGTCCACTTCACCAAGCCTGCCCTTGGACAA GGACCCGATGCCCAACCCCAGGCCTGGCAAGCCCTCGGCCCCTTCCTTGGCCCTTGGCCC ATCCCCAGGAGCCTCGCCCAGCTGGAGGGCTGCACCCAAAGCCTCAGACCTGCTGGGGGC CCGGGGCCCAGGGGGAACCTTCCAGGGCCGAGATCTTCGAGGCGGGGCCCATGCCTCCTC TTCTTCCTTGAACCCCATGCCACCATCGCAGCTGCAGCTCTCAACGGTGGATGCCCACGC CCGGACCCCTGTGCTGCAGGTGCACCCCCTGGAGAGCCCAGCCATGATCAGCCTCACACC ACCCACCACCGCCACTGGGGTCTTCTCCCTCAAGGCCCGGCCTGGCCTCCCACCTGGGAT CAACGTGGCCAGCCTGGAATGGGTGTCCAGGGAGCCGGCACTGCTCTGCACCTTCCCAAA TCCCAGTGCACCCAGGAAGGACAGCACCCTTTCGGCTGTGCCCCAGAGCTCCTACCCACT GCTGGCAAATGGTGTCTGCAAGTGGCCCGGATGTGAGAAGGTCTTCGAAGAGCCAGAGGA CTTCCTCAAGCACTGCCAGGCGGACCATCTTCTGGATGAGAAGGGCAGGGCACAATGTCT CCTCCAGAGAGAGATGGTACAGTCTCTGGAGCAGCAGCTGGTGCTGGAGAAGGAGAAGCT GAGTGCCATGCAGGCCCACCTGGCTGGGAAAATGGCACTGACCAAGGCTTCATCTGTGGC ATCATCCGACAAGGGCTCCTGCTGCATCGTAGCTGCTGGCAGCCAAGGCCCTGTCGTCCC AGCCTGGTCTGGCCCCCGGGAGGCCCCTGACAGCCTGTTTGCTGTCCGGAGGCACCTGTG GGGTAGCCATGGAAACAGCACATTCCCAGAGTTCCTCCACAACATGGACTACTTCAAGTT CCACAACATGCGACCCCCTTTCACCTACGCCACGCTCATCCGCTGGGCCATCCTGGAGGC TCCAGAGAAGCAGCGGACACTCAATGAGATCTACCACTGGTTCACACGCATGTTTGCCTT CTTCAGAAACCATCCTGCCACCTGGAAGGTGAGCTCCTCTGAGGTGGCGGTGACTGGGAT GGCCTCAAGTGCCATCGCAGCTCAAAGTGGGCAGGCCTGGGTCTGGGCTCATAGGCACAT TGGGGAGGAACGGGATGTGGGTTGTTGGTGGTGGCTGCTGGCCTCAGAGGTTGACGCCCA CCTGCTCCCTGTCCCCGGCCTTCCACAGAACGCCATCCGCCACAACCTGAGTCTGCACAA GTGCTTTGTGCGGGTGGAGAGCGAGAAGGGGGCTGTGTGGACCGTGGATGAGCTGGAGTT CCGCAAGAAACGGAGCCAGAGGCCCAGCAGGTGTTCCAACCCTACACCTGGCCCCTGACC TCAAGATCAAGGAAAGGAGGATGGACGAACAGGGGCCAAACTGGTGGGAGGCAGAGGTGG TGGGGGCAGGGATGATAGGCCCTGGATGTGCCCACAGGGACCAAGAAGTGAGGTTTCCAC TGTCTTGCCTGCCAGGGCCCCTGTTCCCCCGCTGGCAGCCACCCCCTCCCCCATCATATC CTTTGCCCCAAGGCTGCTCAGAGGGGCCCCGGTCCTGGCCCCAGCCCCCACCTCCGCCCC AGACACACCCCCCAGTCGAGCCCTGCAGCCAAACAGAGCCTTCACAACCAGCCACACAGA GCCTGCCTCAGCTGCTCGCACAGATTACTTCAGGGCTGGAAAAGTCACACAGACACACAA AATGTCACAATCCTGTCCCTCACTCAACACAAACCCCAAAACACAGAGAGCCTGCCTCAG TACACTCAAACAACCTCAAAGCTGCATCATCACACAATCACACACAAGCACAGCCCTGAC AACCCACACACCCCAAGGCACGCACCCACAGCCAGCCTCAGGGCCCACAGGGGCACTGTC AACACAGGGGTGTGCCCAGAGGCCTACACAGAAGCAGCGTCAGTACCCTCAGGATCTGAG GTCCCAACACGTGCTCGCTCACACACACGGCCTGTTAGAATTCACCTGTGTATCTCACGC ATATGCACACGCACAGCCCCCCAGTGGGTCTCTTGAGTCCCGTGCAGACACACACAGCCA CACACACTGCCTTGCCAAAAATACCCCGTGTCTCCCCTGCCACTCACCTCACTCCCATTC CCTGAGCCCTGATCCATGCCTCAGCTTAGACTGCAGAGGAACTACTCATTTATTTGGGAT CCAAGGCCCCCAACCCACAGTACCGTCCCCAATAAACTGCAGCCGAGCTCCCCACA |
Protein Sequence | >50943 : length: 564 MTRKGQRKKPKISKFPFKSHNQEKEKHREREKKNYENPSPPRDYQRTHSSKKIWIIRRER SAASTPYSVVFLLGIKAKLFLIRDSFPQARLILFCQSTSPSLPLDKDPMPNPRPGKPSAP SLALGPSPGASPSWRAAPKASDLLGARGPGGTFQGRDLRGGAHASSSSLNPMPPSQLQLS TVDAHARTPVLQVHPLESPAMISLTPPTTATGVFSLKARPGLPPGINVASLEWVSREPAL LCTFPNPSAPRKDSTLSAVPQSSYPLLANGVCKWPGCEKVFEEPEDFLKHCQADHLLDEK GRAQCLLQREMVQSLEQQLVLEKEKLSAMQAHLAGKMALTKASSVASSDKGSCCIVAAGS QGPVVPAWSGPREAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHNMRPPFTYATLIR WAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKVSSSEVAVTGMASSAIAAQSGQAWV WAHRHIGEERDVGCWWWLLASEVDAHLLPVPGLPQNAIRHNLSLHKCFVRVESEKGAVWT VDELEFRKKRSQRPSRCSNPTPGP |