| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4982 |
Name | TNFRSF11B |
Synonym | OCIF|OPG|TR1;tumor necrosis factor receptor superfamily, member 11b;TNFRSF11B;tumor necrosis factor receptor superfamily, member 11b |
Definition | osteoclastogenesis inhibitory factor|osteoprotegerin|tumor necrosis factor receptor superfamily member 11B |
Position | 8q24 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Disease | Bone Mineral Density;GAD |
Disease | fractures;GAD |
Disease | Bone mineral density (spine);GAD |
Disease | Paget disease, juvenile;OMIM |
Disease | Bone mineral density (hip);GAD |
Disease | Paget's disease;GAD |
Disease | Bone mineral density;NHGRI |
Disease | vascular function;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Osteoporosis;GAD |
Disease | bone density;GAD |
Disease | Osteoporosis;NHGRI |
Disease | osteoporotic fractures;GAD |
Disease | METABOLIC;GAD |
Disease | left ventricular hypertrophy;GAD |
Disease | Bone mineral density (spine);NHGRI |
Disease | vascular morphology;GAD |
Disease | Bone mineral density (hip);NHGRI |
External Links | |
Links to Entrez Gene | 4982 |
Links to all GeneRIF Items | 4982 |
Links to iHOP | 4982 |
Sequence Information | |
Nucleotide Sequence | >4982 : length: 2354 TTTTTTTCCCCTGCTCTCCCAGGGGCCAGACACCACCGCCCCACCCCTCACGCCCCACCT CCCTGGGGGATCCTTTCCGCCCCAGCCCTGAAAGCGTTAACCCTGGAGCTTTCTGCACAC CCCCCGACCGCTCCCGCCCAAGCTTCCTAAAAAAGAAAGGTGCAAAGTTTGGTCCAGGAT AGAAAAATGACTGATCAAAGGCAGGCGATACTTCCTGTTGCCGGGACGCTATATATAACG TGATGAGCGCACGGGCTGCGGAGACGCACCGGAGCGCTCGCCCAGCCGCCGCCTCCAAGC CCCTGAGGTTTCCGGGGACCACAATGAACAACTTGCTGTGCTGCGCGCTCGTGTTTCTGG ACATCTCCATTAAGTGGACCACCCAGGAAACGTTTCCTCCAAAGTACCTTCATTATGACG AAGAAACCTCTCATCAGCTGTTGTGTGACAAATGTCCTCCTGGTACCTACCTAAAACAAC ACTGTACAGCAAAGTGGAAGACCGTGTGCGCCCCTTGCCCTGACCACTACTACACAGACA GCTGGCACACCAGTGACGAGTGTCTATACTGCAGCCCCGTGTGCAAGGAGCTGCAGTACG TCAAGCAGGAGTGCAATCGCACCCACAACCGCGTGTGCGAATGCAAGGAAGGGCGCTACC TTGAGATAGAGTTCTGCTTGAAACATAGGAGCTGCCCTCCTGGATTTGGAGTGGTGCAAG CTGGAACCCCAGAGCGAAATACAGTTTGCAAAAGATGTCCAGATGGGTTCTTCTCAAATG AGACGTCATCTAAAGCACCCTGTAGAAAACACACAAATTGCAGTGTCTTTGGTCTCCTGC TAACTCAGAAAGGAAATGCAACACACGACAACATATGTTCCGGAAACAGTGAATCAACTC AAAAATGTGGAATAGATGTTACCCTGTGTGAGGAGGCATTCTTCAGGTTTGCTGTTCCTA CAAAGTTTACGCCTAACTGGCTTAGTGTCTTGGTAGACAATTTGCCTGGCACCAAAGTAA ACGCAGAGAGTGTAGAGAGGATAAAACGGCAACACAGCTCACAAGAACAGACTTTCCAGC TGCTGAAGTTATGGAAACATCAAAACAAAGACCAAGATATAGTCAAGAAGATCATCCAAG ATATTGACCTCTGTGAAAACAGCGTGCAGCGGCACATTGGACATGCTAACCTCACCTTCG AGCAGCTTCGTAGCTTGATGGAAAGCTTACCGGGAAAGAAAGTGGGAGCAGAAGACATTG AAAAAACAATAAAGGCATGCAAACCCAGTGACCAGATCCTGAAGCTGCTCAGTTTGTGGC GAATAAAAAATGGCGACCAAGACACCTTGAAGGGCCTAATGCACGCACTAAAGCACTCAA AGACGTACCACTTTCCCAAAACTGTCACTCAGAGTCTAAAGAAGACCATCAGGTTCCTTC ACAGCTTCACAATGTACAAATTGTATCAGAAGTTATTTTTAGAAATGATAGGTAACCAGG TCCAATCAGTAAAAATAAGCTGCTTATAACTGGAAATGGCCATTGAGCTGTTTCCTCACA ATTGGCGAGATCCCATGGATGAGTAAACTGTTTCTCAGGCACTTGAGGCTTTCAGTGATA TCTTTCTCATTACCAGTGACTAATTTTGCCACAGGGTACTAAAAGAAACTATGATGTGGA GAAAGGACTAACATCTCCTCCAATAAACCCCAAATGGTTAATCCAACTGTCAGATCTGGA TCGTTATCTACTGACTATATTTTCCCTTATTACTGCTTGCAGTAATTCAACTGGAAATTA AAAAAAAAAAACTAGACTCCATTGTGCCTTACTAAATATGGGAATGTCTAACTTAAATAG CTTTGAGATTTCAGCTATGCTAGAGGCTTTTATTAGAAAGCCATATTTTTTTCTGTAAAA GTTACTAATATATCTGTAACACTATTACAGTATTGCTATTTATATTCATTCAGATATAAG ATTTGTACATATTATCATCCTATAAAGAAACGGTATGACTTAATTTTAGAAAGAAAATTA TATTCTGTTTATTATGACAAATGAAAGAGAAAATATATATTTTTAATGGAAAGTTTGTAG CATTTTTCTAATAGGTACTGCCATATTTTTCTGTGTGGAGTATTTTTATAATTTTATCTG TATAAGCTGTAATATCATTTTATAGAAAATGCATTATTTAGTCAATTGTTTAATGTTGGA AAACATATGAAATATAAATTATCTGAATATTAGATGCTCTGAGAAATTGAATGTACCTTA TTTAAAAGATTTTATGGTTTTATAACTATATAAATGACATTATTAAAGTTTTCAAATTAT TTTTTAAAAAAAAA |
Protein Sequence | >4982 : length: 401 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKT VCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLK HRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNAT HDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERI KRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLME SLPGKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALKHSKTYHFPKT VTQSLKKTIRFLHSFTMYKLYQKLFLEMIGNQVQSVKISCL |