| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4773 |
Name | NFATC2 |
Synonym | NFAT1|NFATP;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2;NFATC2;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
Definition | NF-ATc2|NFAT pre-existing subunit|NFAT transcription complex, preexisting component|T cell transcription factor NFAT1|T-cell transcription factor NFAT1|nuclear factor of activated T-cells, cytoplasmic 2|nuclear factor of activated T-cells, preexisting com |
Position | 20q13.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | VEGF signaling pathway;KEGG PATHWAY;hsa04370 |
Pathway | Axon guidance mediated by netrin;PANTHER;P00009 |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Downstream signaling in naive CD8+ T cells;PID Curated;200184 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Noncanonical Wnt signaling pathway;PID Curated;200016 |
Pathway | Role of Calcineurin-dependent NFAT signaling in lymphocytes;PID Curated;200076 |
Pathway | Fc-epsilon receptor I signaling in mast cells;PID Curated;200003 |
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650 |
Pathway | B cell activation;PANTHER;P00010 |
Pathway | Validated transcriptional targets of AP1 family members Fra1 and Fra2;PID Curated;200044 |
Disease | Colon cancer;FunDO |
Disease | Breast cancer;FunDO |
Disease | Aplastic anemia;FunDO |
Disease | Leukoencephalopathy;FunDO |
Disease | Lymphoma;FunDO |
External Links | |
Links to Entrez Gene | 4773 |
Links to all GeneRIF Items | 4773 |
Links to iHOP | 4773 |
Sequence Information | |
Nucleotide Sequence | >4773 : length: 7530 AGCAGGAAGCTCGCGCCGCCGTCGCCGCCGCCGCTCAGCTTCCCCGGGCGCGTCCAGGAC CCGCTGCGCCAGGCGCGCCGTCCCCGGACCCGGCGTGCGTCCCTACGAGGAAAGGGACCC CGCCGCTCGAGCCGCCTCCGCCAGCCCCACTGCGAGGGGTCCCAGAGCCAGCCGCGCCCG CCCTCGCCCCCGGCCCCGCAGCCTTCCCGCCCTGCGCGCCATGAACGCCCCCGAGCGGCA GCCCCAACCCGACGGCGGGGACGCCCCAGGCCACGAGCCTGGGGGCAGCCCCCAAGACGA GCTTGACTTCTCCATCCTCTTCGACTATGAGTATTTGAATCCGAACGAAGAAGAGCCGAA TGCACATAAGGTCGCCAGCCCACCCTCCGGACCCGCATACCCCGATGATGTCCTGGACTA TGGCCTCAAGCCATACAGCCCCCTTGCTAGTCTCTCTGGCGAGCCCCCCGGCCGATTCGG AGAGCCGGATAGGGTAGGGCCGCAGAAGTTTCTGAGCGCGGCCAAGCCAGCAGGGGCCTC GGGCCTGAGCCCTCGGATCGAGATCACTCCGTCCCACGAACTGATCCAGGCAGTGGGGCC CCTCCGCATGAGAGACGCGGGCCTCCTGGTGGAGCAGCCGCCCCTGGCCGGGGTGGCCGC CAGCCCGAGGTTCACCCTGCCCGTGCCCGGCTTCGAGGGCTACCGCGAGCCGCTTTGCTT GAGCCCCGCTAGCAGCGGCTCCTCTGCCAGCTTCATTTCTGACACCTTCTCCCCCTACAC CTCGCCCTGCGTCTCGCCCAATAACGGCGGGCCCGACGACCTGTGTCCGCAGTTTCAAAA CATCCCTGCTCATTATTCCCCCAGAACCTCGCCAATAATGTCACCTCGAACCAGCCTCGC CGAGGACAGCTGCCTGGGCCGCCACTCGCCCGTGCCCCGTCCGGCCTCCCGCTCCTCATC GCCTGGTGCCAAGCGGAGGCATTCGTGCGCCGAGGCCTTGGTTGCCCTGCCGCCCGGAGC CTCACCCCAGCGCTCCCGGAGCCCCTCGCCGCAGCCCTCATCTCACGTGGCACCCCAGGA CCACGGCTCCCCGGCTGGGTACCCCCCTGTGGCTGGCTCTGCCGTGATCATGGATGCCCT GAACAGCCTCGCCACGGACTCGCCTTGTGGGATCCCCCCCAAGATGTGGAAGACCAGCCC TGACCCCTCGCCGGTGTCTGCCGCCCCATCCAAGGCCGGCCTGCCTCGCCACATCTACCC GGCCGTGGAGTTCCTGGGGCCCTGCGAGCAGGGCGAGAGGAGAAACTCGGCTCCAGAATC CATCCTGCTGGTTCCGCCCACTTGGCCCAAGCCGCTGGTGCCTGCCATTCCCATCTGCAG CATCCCAGTGACTGCATCCCTCCCTCCACTTGAGTGGCCGCTGTCCAGTCAGTCAGGCTC TTACGAGCTGCGGATCGAGGTGCAGCCCAAGCCACATCACCGGGCCCACTATGAGACAGA AGGCAGCCGAGGGGCTGTCAAAGCTCCAACTGGAGGCCACCCTGTGGTTCAGCTCCATGG CTACATGGAAAACAAGCCTCTGGGACTTCAGATCTTCATTGGGACAGCTGATGAGCGGAT CCTTAAGCCGCACGCCTTCTACCAGGTGCACCGAATCACGGGGAAAACTGTCACCACCAC CAGCTATGAGAAGATAGTGGGCAACACCAAAGTCCTGGAGATACCCTTGGAGCCCAAAAA CAACATGAGGGCAACCATCGACTGTGCGGGGATCTTGAAGCTTAGAAACGCCGACATTGA GCTGCGGAAAGGCGAGACGGACATTGGAAGAAAGAACACGCGGGTGAGACTGGTTTTCCG AGTTCACATCCCAGAGTCCAGTGGCAGAATCGTCTCTTTACAGACTGCATCTAACCCCAT CGAGTGCTCCCAGCGATCTGCTCACGAGCTGCCCATGGTTGAAAGACAAGACACAGACAG CTGCCTGGTCTATGGCGGCCAGCAAATGATCCTCACGGGGCAGAACTTTACATCCGAGTC CAAAGTTGTGTTTACTGAGAAGACCACAGATGGACAGCAAATTTGGGAGATGGAAGCCAC GGTGGATAAGGACAAGAGCCAGCCCAACATGCTTTTTGTTGAGATCCCTGAATATCGGAA CAAGCATATCCGCACACCTGTAAAAGTGAACTTCTACGTCATCAATGGGAAGAGAAAACG AAGTCAGCCTCAGCACTTTACCTACCACCCAGTCCCAGCCATCAAGACGGAGCCCACGGA TGAATATGACCCCACTCTGATCTGCAGCCCCACCCATGGAGGCCTGGGGAGCCAGCCTTA CTACCCCCAGCACCCGATGGTGGCCGAGTCCCCCTCCTGCCTCGTGGCCACCATGGCTCC CTGCCAGCAGTTCCGCACGGGGCTCTCATCCCCTGACGCCCGCTACCAGCAACAGAACCC AGCGGCCGTACTCTACCAGCGGAGCAAGAGCCTGAGCCCCAGCCTGCTGGGCTATCAGCA GCCGGCCCTCATGGCCGCCCCGCTGTCCCTTGCGGACGCTCACCGCTCTGTGCTGGTGCA CGCCGGCTCCCAGGGCCAGAGCTCAGCCCTGCTCCACCCCTCTCCGACCAACCAGCAGGC CTCGCCTGTGATCCACTACTCACCCACCAACCAGCAGCTGCGCTGCGGAAGCCACCAGGA GTTCCAGCACATCATGTACTGCGAGAATTTCGCACCAGGCACCACCAGACCTGGCCCGCC CCCGGTCAGTCAAGGTCAGAGGCTGAGCCCGGGTTCCTACCCCACAGTCATTCAGCAGCA GAATGCCACGAGCCAAAGAGCCGCCAAAAACGGACCCCCGGTCAGTGACCAAAAGGAAGT ATTACCTGCGGGGGTGACCATTAAACAGGAGCAGAACTTGGACCAGACCTACTTGGATGA TGAGCTGATAGACACACACCTTAGCTGGATACAAAACATATTATGAAACAGAATGACTGT GATCTTTGATCCGAGAAATCAAAGTTAAAGTTAATGAAATTATCAGGAAGGAGTTTTCAG GACCTCCTGCCAGAAATCAGACGTAAAAGAAGCCATTATAGCAAGACACCTTCTGTATCT GACCCCTCGGAGCCCTCCACAGCCCCTCACCTTCTGTCTCCTTTCATGTTCATCTCCCAG CCCGGAGTCCACACGCGGATCAATGTATGGGCACTAAGCGGACTCTCACTTAAGGAGCTC GCCACCTCCCTCTAAACACCAGAGAGAACTCTTCTTTTCGGTTTATGTTTTAAATCCCAG AGAGCATCCTGGTTGATCTTAATGGTGTTCCGTCCAAATAGTAAGCACCTGCTGACCAAA AGCACATTCTACATGAGACAGGACACTGGAACTCTCCTGAGAACAGAGTGACTGGAGCTT GGGGGGATGGACGGGGGACAGAAGATGTGGGCACTGTGATTAAACCCCAGCCCTTGCGTT CGTTTTTCCAGGTCACAGATACAGCTCCTGTACCTTTTGAAGGCAAGGAGTTCTCAGAGC AACCAAAGGAACGTGACCCAAGAGCCCAGCTTACAGGCTGAAGAAACCCAAAACCCTCGA TAGAGACAGAAACTGAACTGTCAGTCCTTAGAGCTCGCCCAGTCCATGCCACAACTGGGC CACAGCTAAAGCTTTATTTTTGAATTCTCATTCCAAAACCAAACTGTCTTGCCCAGACAA GATCACCTGTTAAGACTTCTTGGCGTTAAGTTATGACATGTATACGCGTTTGTTATTATT ATTTTTTCTGCTTTAAAAGGCTGACCAGGGCACCTAGCCCTGGAGCTGTCTTGGCGAGCT GTTCTTTAACCCCTGCAGCACGCAGTCCTGCTAACACAATTTCCATAGACTTGGGGGGCT GACCCAGGCTGCAGAGAGCAAGCACCTGTCTGCTGCAGCTGTACAACCTGGATGCTTTGC AAGGTTCCGGCTTGCTTTCTTCCTAGCAGCCAGAGTGCTTTTCCGTAAAGCGGTGGAGAA TCTCAAGCATGTGCATTTAATTGAGGAATAGCAGAAGGGCTAAAGCAACCAAGAAAAGAA GTGTGGGTATTTTTGTTAAGTAAAACAGCCCAAGTGCTTCTGGAGGTGGGTTTCTACCAA GATAGAGGAAAAGGGCTGAATTCCCTCTAAGTGGGACAGCCGAGCTCAGGATGTGCTTCC CAGCTTCACTGGTTAATTTGACCTGAACCTATTTAAAGATCCCTTCTGCCCCTGAAGACC TATCCGCACTCAAATTCTAACATGAAGAAATCTACTCGAATGCATCCTTTACTTTGAATG AGCTCTATTCGGTTGCATGTTATATGTGATTTCCTTCCTCCCAACTGTTTCCACTGAGCG CACCCAGTCTCCCCTAGTCTTCCTCTGTGGGTGTGATTTTTGTGATTTTTACAAACAAAA CCCTTGAAGTTCTTGGCAGATGTGTTTGTTTCTGTTTGCATGTACTGCAGATACCCCAGG ACAAGCGGGGGATTCATTTTTCAGCCATTCAGTTGTTTCCTCAATAATCCGCAGCAAAGT GAAAATATTCTTAGCACTCAGACTGTACTTAGAGTGTTTTCTCAGTCCAGTCTGTACAGT CTGTAGGCAGAAGGCCTCAGAAGAAAGTCATGGCCACTCAGTGCCCACTGTGGGCTTTGT AAGTCCTGGCTCTCCCGTCAAGGTTACCCAGAGGTAAAAGCTTCCTGGGAGTGGGGCCAG GTGTGTTTGGCACTCCAGATAGAAGGCAAAATGCTCAGATTCGGGCCTGTGCACTTGTAT GCAACCTGTCGGTCGATACCTAGCATTTATTTTTCCCTGACAATGAACGACCTTTCCCTC ACCCACCCTAAGCTCAAAGAGTTTAGCAAAATTCTCTTTTAAATAAACAGAATGCCAGTA AGAGGTTGACCCCTACCATGGAACTTCTGGGATGCTAAATACTTCCTCATGAACAAAATA AGTTCCTTATTATAAGTTCCTTATACTAGCAGCTTCACCTAAAGAATTTTCTCTCCAGCA ATATTGACTTCACTGGGGAAAAGCCAAGAGTGTGTGGTGAGTGATTTGTTCTCACTCGAC CTGGCTAGGACTGGCTAGGAGCTGTTTTTTGTACATGAGGGAATTTGGGCTTTCCTCAGT TATCTGAATGTTTTACCCAAGTGCCTTCCTGCTATTGTAGCAAAGTAGCTCAGCTTCCTT GTCCACAGGGTGAAAAAGGACTAATGCATTTTCCATCAGTTTTCTAACTATGTTAGCAAA AACGGCCTCCTGGTAGCTCAACCTCCTGTACGCGTGTGTGTGTGTAATACACACACAAAT AAACCCCTCTGTTTTTCTAAGACATCTTAGCTGGATATTATAGGAAGCACTTTCATAAAC AACTGTAACAAATCGCAAAGGAAAGAGAAACAAAAGCATTAGATTTGAGACATAAACAGG CAAGAGAAAGTGTATTAGGAACTGACAGCTATCAAGGAAGTTTTGTCAGTTACAAATGCT AGGAGGAAATTTTGCCAAGAAGGATGGCTCATGAAATATTTCCAGTACGGGAAGAGGCAA TAAGATCCTCTAAGAGAATGAGAAAGTAGGGGTGTCTAAATGGTAAAGATGGGTGTGTTG CACGTGTGTTAGAAGGATCTCAGTTGAGTGAAGGTTTGCACTGCTACATCTAAGTTAATG TAAATATGTAGCACTCTGACAGGTCTACCGTGTTGCTGAATGTAGTATATTTCCAAAGTT TGCAAGTCTTCCTGTATTGTACAAAGATGCTGCTGCTTGATAATATGTATAGCAATCCAG ATTAGTATGTTATTAAATTTTATTTTCTTACCTGTATTTTTATGCTTTTTACCTGTCCTC AAAATATTACACCCCTGTTGGAATTAGATTTATATTTATAAATGGTCAGAAATCTTTTTA AGTGTCTCTTTTTACACATAGGTTGATTTTTTTTTCTTAAGAGAAATGATGTATTCTTGA AACATTTGTTACTCATTCCAGGAAACAAAAACCCATATAATAAAACCCCCACTCAGAGCC TGTTAGTCACCTCTCTAGAAGATGGCATCTCAGGAGAAGGAATGGCTTTGTGGAAGAAGG AATCACCTTTTTCTTGCTCAAGAATTATGCTGACTTCAGCCCTGAGCCTGGATCTGGTCA CTGAGAATCATCAAGTGTCTAGATCCTCCCCCCAAAATAACTAATTTAGTAGGTGATTTT GATTTTAAAAAATTGACACCAAAACCCTGCCTGCATTGTAATGGAATTCGAAAAGAATTC ATGTTCACAGAACTCAACGTTCAGGCTAATATTTACAGAAGGGACCAAATCTAAATCCTG GTAGATAACTCCTGTATGCTTTATCCAAAGGACACCCACAGTTTTCCAGCATAGATATAA CCAAGGATGAATTGATTCCTTCAAAGAACTGGGAGGCACGGATATTGCATTTTTTGTTTA CATCCAGTAGCCAAGACGCCTCAGTGAGCCAGTCTTGGGCAGAGGCTGTCACATTTAGGC AGATTGGAAGTTGGTATGTTCTAATTCTCACTCTGGACTACAGTGAGGCTGAATTTATCA TGTCAAAAAAAAAAAAAAAAAAAGACCTTTCCAAGTGCTTTCTATTGCTCAGAATTGAAA GAATGTTTTCATTTCAAGTTTACAAGAGGCATGGATGGAGTTGTGACGTTCTTGACAAGC TGGGCTAACCTTTCCCGAACTTGTTTCCCGGAGGCAAGGTGCTCGGTGACCCAGCGCATC TTAACCTTGGGTCTCCTAGGCTCGAGGCTAGGGCATTACGTTTCGTGGAACCAAAGCAGC CAATTGCATAGCAAGTATTTTCCTGCATTCCAATTAAATGCTTAAGAAAAAGCAGCATCC TATAAAATTGTGATCATAAACATCCATTTCCCTCAGCTTTTGTGAGTGCCTTGACTTACA GCCAACATCACTGTTTAACTCAGTCTGTTTAAAAACAAACTTTTCTGGTGGTTGATAACA GAGAGTTGCTCCCTGAGCCATCAGGGTCCTGGGAGCTGGAAGTGAAAGGGTTATTAACAT TCTACCTTTATGCAGCTGTTGGCTGACCAGAATAAACTCCCTGCTGAGTTCAAGCTTTGA ATGGAATGGATGCAAATGATGTTGTTTCCATTAGAGCAGGTGCTCACAGCATTCTGATTG GCCTGAGCAGACCGAGGCTATGGCTGTTGGGACAAGCTTAGCATCCTGGACATCTTGTCA AAGAACCTCACTCACCCCTCTGGCCTCTACAGCCCTCAGAGGAGAGAAAACCAATTCTCC AACAAACAGGTCTCTCCAACATGGTGGTGCTGGCAGGCTTAGGTTTAGAAAATCCTGACT GTTAAAGGCGTTTGAATACATCACATTCCTATGCAAATGTTTTTAATCTCCAGTTTAATG TAGTTTATTTTTCCTATATGTAAAGTATTTTTATACGGCTTGTATCATGATAGTTTAGCA ATAAAACAGTTGGAAGCAACATCTAAAAAA |
Protein Sequence | >4773 : length: 940 MNAPERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAY PDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHE LIQAVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFIS DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPR PASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGS AVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGER RNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHH RAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRIT GKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNT RVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTG QNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYV INGKRKRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPTHGGLGSQPYYPQHPMVAESPSC LVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADA HRSVLVHAGSQGQSSALLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPG TTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNL DQTYLDDDFTDFTHSGFLSGPIRRLNCAPITEVPHISKAH |