| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 468 |
Name | ATF4 |
Synonym | CREB-2|CREB2|TAXREB67|TXREB;activating transcription factor 4;ATF4;activating transcription factor 4 |
Definition | DNA-binding protein TAXREB67|cAMP response element-binding protein 2|cAMP-dependent transcription factor ATF-4|cAMP-responsive element-binding protein 2|cyclic AMP-dependent transcription factor ATF-4|cyclic AMP-responsive element-binding protein 2|tax-re |
Position | 22q13.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Prostate cancer;KEGG PATHWAY;hsa05215 |
Pathway | PERK regulated gene expression;PID Reactome;500132 |
Pathway | Validated transcriptional targets of AP1 family members Fra1 and Fra2;PID Curated;200044 |
Pathway | Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141 |
Pathway | GnRH signaling pathway;KEGG PATHWAY;hsa04912 |
Disease | Embryoma;FunDO |
Disease | Bipolar disorder;FunDO |
External Links | |
Links to Entrez Gene | 468 |
Links to all GeneRIF Items | 468 |
Links to iHOP | 468 |
Sequence Information | |
Nucleotide Sequence | >468 : length: 2041 AGCCATTTCTACTTTGCCCGCCCACAGATGTAGTTTTCTCTGCGCGTGTGCGTTTTCCCT CCTCCCCGCCCTCAGGGTCCACGGCCACCATGGCGTATTAGGGGCAGCAGTGCCTGCGGC AGCATTGGCCTTTGCAGCGGCGGCAGCAGCACCAGGCTCTGCAGCGGCAACCCCCAGCGG CTTAAGCCATGGCGTGAGTACCGGGGCGGGTCGTCCAGCTGTGCTCCTGGGGCCGGCGCG GGTTTTGGATTGGTGGGGTGCGGCCTGGGGCCAGGGCGGTGCCGCCAAGGGGGAAGCGAT TTAACGAGCGCCCGGGACGCGTGGTCTTTGCTTGGGTGTCCCCGAGACGCTCGCGTGCCT GGGATCGGGAAAGCGTAGTCGGGTGCCCGGACTGCTTCCCCAGGAGCCCTACAGCCCTCG GACCCCGAGCCCCGCAAGGGTCCCAGGGGTCTTGGCTGTTGCCCCACGAAACGTGGCAGG AACCAAGATGGCGGCGGCAGGGCGGCGGCGCGGGCGTGAGTCAAGGGCGGGCGGTGGGCG GGGCGCGGCCGCCCTGGCCGTATTTGGACGTGGGGACGGAGCGCTTTCCTCTTGGCGGCC GGTGGAAGAATCCCCTGGTCTCCGTGAGCGTCCATTTTGTGGAACCTGAGTTGCAAGCAG GGAGGGGCAAATACAACTGCCCTGTTCCCGATTCTCTAGATGGCCGATCTAGAGAAGTCC CGCCTCATAAGTGGAAGGATGAAATTCTCAGAACAGCTAACCTCTAATGGGAGTTGGCTT CTGATTCTCATTCAGGCTTCTCACGGCATTCAGCAGCAGCGTTGCTGTAACCGACAAAGA CACCTTCGAATTAAGCACATTCCTCGATTCCAGCAAAGCACCGCAACATGACCGAAATGA GCTTCCTGAGCAGCGAGGTGTTGGTGGGGGACTTGATGTCCCCCTTCGACCAGTCGGGTT TGGGGGCTGAAGAAAGCCTAGGTCTCTTAGATGATTACCTGGAGGTGGCCAAGCACTTCA AACCTCATGGGTTCTCCAGCGACAAGGCTAAGGCGGGCTCCTCCGAATGGCTGGCTGTGG ATGGGTTGGTCAGTCCCTCCAACAACAGCAAGGAGGATGCCTTCTCCGGGACAGATTGGA TGTTGGAGAAAATGGATTTGAAGGAGTTCGACTTGGATGCCCTGTTGGGTATAGATGACC TGGAAACCATGCCAGATGACCTTCTGACCACGTTGGATGACACTTGTGATCTCTTTGCCC CCCTAGTCCAGGAGACTAATAAGCAGCCCCCCCAGACGGTGAACCCAATTGGCCATCTCC CAGAAAGTTTAACAAAACCCGACCAGGTTGCCCCCTTCACCTTCTTACAACCTCTTCCCC TTTCCCCAGGGGTCCTGTCCTCCACTCCAGATCATTCCTTTAGTTTAGAGCTGGGCAGTG AAGTGGATATCACTGAAGGAGATAGGAAGCCAGACTACACTGCTTACGTTGCCATGATCC CTCAGTGCATAAAGGAGGAAGACACCCCTTCAGATAATGATAGTGGCATCTGTATGAGCC CAGAGTCCTATCTGGGGTCTCCTCAGCACAGCCCCTCTACCAGGGGCTCTCCAAATAGGA GCCTCCCATCTCCAGGTGTTCTCTGTGGGTCTGCCCGTCCCAAACCTTACGATCCTCCTG GAGAGAAGATGGTAGCAGCAAAAGTAAAGGGTGAGAAACTGGATAAGAAGCTGAAAAAAA TGGAGCAAAACAAGACAGCAGCCACTAGGTACCGCCAGAAGAAGAGGGCGGAGCAGGAGG CTCTTACTGGTGAGTGCAAAGAGCTGGAAAAGAAGAACGAGGCTCTAAAAGAGAGGGCGG ATTCCCTGGCCAAGGAGATCCAGTACCTGAAAGATTTGATAGAAGAGGTCCGCAAGGCAA GGGGGAAGAAAAGGGTCCCCTAGTTGAGGATAGTCAGGAGCGTCAATGTGCTTGTACATA GAGTGCTGTAGCTGTGTGTTCCAATAAATTATTTTGTAGGGAAAGTAAAAAAAAAAAAAA A |
Protein Sequence | >468 : length: 351 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC DLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL ELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP |