| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4322 |
Name | MMP13 |
Synonym | CLG3|MANDP1|MMP-13;matrix metallopeptidase 13;MMP13;matrix metallopeptidase 13 |
Definition | collagenase 3|matrix metallopeptidase 13 (collagenase 3)|matrix metalloproteinase 13 (collagenase 3) |
Position | 11q22.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Alzheimer disease-presenilin pathway;PANTHER;P00004 |
Pathway | Plasminogen activating cascade;PANTHER;P00050 |
Disease | Melanoma;FunDO |
Disease | Peripheral nerve sheath cancer;FunDO |
Disease | Polyarthritis;FunDO |
Disease | Oral cancer;FunDO |
Disease | Breast cancer;FunDO |
Disease | Mucocutaneous lymph node syndrome;FunDO |
Disease | Alveolar bone loss;FunDO |
Disease | IMMUNE;GAD |
Disease | Rheumatoid arthritis;FunDO |
Disease | esophageal cancer gastric cardiac cancer;GAD |
Disease | rheumatoid arthritis;GAD |
Disease | Colon cancer;FunDO |
Disease | Periodontal disease;FunDO |
Disease | Spondyloepimetaphyseal dysplasia, Missouri type;OMIM |
Disease | CARDIOVASCULAR;GAD |
Disease | Stroke;FunDO |
Disease | CANCER;GAD |
Disease | Metaphyseal anadysplasia 1;OMIM |
Disease | Lyme disease;FunDO |
Disease | Endometriosis;FunDO |
Disease | Heart failure;FunDO |
Disease | Squamous cell cancer;FunDO |
Disease | Metastasis to lymph nodes;FunDO |
Disease | Osteoporosis;FunDO |
Disease | gastric cardia adenocarcinoma and esophageal squamous cell carcinoma;GAD |
Disease | Atherosclerosis;GAD |
Disease | Myelofibrosis;FunDO |
External Links | |
Links to Entrez Gene | 4322 |
Links to all GeneRIF Items | 4322 |
Links to iHOP | 4322 |
Sequence Information | |
Nucleotide Sequence | >4322 : length: 2735 ACAACAGTCCCCAGGCATCACCATTCAAGATGCATCCAGGGGTCCTGGCTGCCTTCCTCT TCTTGAGCTGGACTCATTGTCGGGCCCTGCCCCTTCCCAGTGGTGGTGATGAAGATGATT TGTCTGAGGAAGACCTCCAGTTTGCAGAGCGCTACCTGAGATCATACTACCATCCTACAA ATCTCGCGGGAATCCTGAAGGAGAATGCAGCAAGCTCCATGACTGAGAGGCTCCGAGAAA TGCAGTCTTTCTTCGGCTTAGAGGTGACTGGCAAACTTGACGATAACACCTTAGATGTCA TGAAAAAGCCAAGATGCGGGGTTCCTGATGTGGGTGAATACAATGTTTTCCCTCGAACTC TTAAATGGTCCAAAATGAATTTAACCTACAGAATTGTGAATTACACCCCTGATATGACTC ATTCTGAAGTCGAAAAGGCATTCAAAAAAGCCTTCAAAGTTTGGTCCGATGTAACTCCTC TGAATTTTACCAGACTTCACGATGGCATTGCTGACATCATGATCTCTTTTGGAATTAAGG AGCATGGCGACTTCTACCCATTTGATGGGCCCTCTGGCCTGCTGGCTCATGCTTTTCCTC CTGGGCCAAATTATGGAGGAGATGCCCATTTTGATGATGATGAAACCTGGACAAGTAGTT CCAAAGGCTACAACTTGTTTCTTGTTGCTGCGCATGAGTTCGGCCACTCCTTAGGTCTTG ACCACTCCAAGGACCCTGGAGCACTCATGTTTCCTATCTACACCTACACCGGCAAAAGCC ACTTTATGCTTCCTGATGACGATGTACAAGGGATCCAGTCTCTCTATGGTCCAGGAGATG AAGACCCCAACCCTAAACATCCAAAAACGCCAGACAAATGTGACCCTTCCTTATCCCTTG ATGCCATTACCAGTCTCCGAGGAGAAACAATGATCTTTAAAGACAGATTCTTCTGGCGCC TGCATCCTCAGCAGGTTGATGCGGAGCTGTTTTTAACGAAATCATTTTGGCCAGAACTTC CCAACCGTATTGATGCTGCATATGAGCACCCTTCTCATGACCTCATCTTCATCTTCAGAG GTAGAAAATTTTGGGCTCTTAATGGTTATGACATTCTGGAAGGTTATCCCAAAAAAATAT CTGAACTGGGTCTTCCAAAAGAAGTTAAGAAGATAAGTGCAGCTGTTCACTTTGAGGATA CAGGCAAGACTCTCCTGTTCTCAGGAAACCAGGTCTGGAGATATGATGATACTAACCATA TTATGGATAAAGACTATCCGAGACTAATAGAAGAAGACTTCCCAGGAATTGGTGATAAAG TAGATGCTGTCTATGAGAAAAATGGTTATATCTATTTTTTCAACGGACCCATACAGTTTG AATACAGCATCTGGAGTAACCGTATTGTTCGCGTCATGCCAGCAAATTCCATTTTGTGGT GTTAAGTGTCTTTTTAAAAATTGTTATTTAAATCCTGAAGAGCATTTGGGGTAATACTTC CAGAAGTGCGGGGTAGGGGAAGAAGAGCTATCAGGAGAAAGCTTGGTTCTGTGAACAAGC TTCAGTAAGTTATCTTTGAATATGTAGTATCTATATGACTATGCGTGGCTGGAACCACAT TGAAGAATGTTAGAGTAATGAAATGGAGGATCTCTAAAGAGCATCTGATTCTTGTTGCTG TACAAAAGCAATGGTTGATGATACTTCCCACACCACAAATGGGACACATGGTCTGTCAAT GAGAGCATAATTTAAAAATATATTTATAAGGAAATTTTACAAGGGCATAAAGTAAATACA TGCATATAATGAATAAATCATTCTTACTAAAAAGTATAAAATAGTATGAAAATGGAAATT TGGGAGAGCCATACATAAAAGAAATAAACCAAAGGAAAATGTCTGTAATAATAGACTGTA ACTTCCAAATAAATAATTTTCATTTTGCACTGAGGATATTCAGATGTATGTGCCCTTCTT CACACAGACACTAACGAAATATCAAAGTCATTAAAGACAGGAGACAAAAGAGCAGTGGTA AGAATAGTAGATGTGGCCTTTGAATTCTGTTTAATTTTCACTTTTGGCAATGACTCAAAG TCTGCTCTCATATAAGACAAATATTCCTTTGCATATTATAAAGGATAAAGAAGGATGATG TCTTTTTATTAAAATATTTCAGGTTCTTCAGAAGTCACACATTACAAAGTTAAAATTGTT ATCAAAATAGTCTAAGGCCATGGCATCCCTTTTTCATAAATTATTTGATTATTTAAGACT AAAAGTTGCATTTTAACCCTATTTTACCTAGCTAATTATTTAATTGTCCAGTTTGTCTTG GATATATAGGCTATTTTCTAAAGACTTGTATAGCATGAAATAAAATATATCTTATAAAGT GGAAGTATGTATATTAAAAAAGAGACATCCAAATTTTTTTTTAAAGCAGTCTACTAGATT GTGATCCCTTGAGATATGGAAGGATGCCTTTTTTTCTCTGCATTTAAAAAAATCCCCCAG CACTTCCCACAGTGCCTATTGATACTTGGGGAGGGTGCTTGGCACTTATTGAATATATGA TCGGCCATCAAGGGAAGAACTATTGTGCTCAGAGACACTGTTGATAAAAACTCAGGCAAA GAAAATGAAATGCATATTTGCAAAGTGTATTAGGAAGTGTTTATGTTGTTTATAATAAAA ATATATTTTCAACAGACAAAAAAAAAAAAAAAAAA |
Protein Sequence | >4322 : length: 471 MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENA ASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTY RIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDG PSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALM FPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGET MIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGY DILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLI EEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC |