| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3984 |
Name | LIMK1 |
Synonym | LIMK|LIMK-1;LIM domain kinase 1;LIMK1;LIM domain kinase 1 |
Definition | LIM motif-containing protein kinase |
Position | 7q11.23 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | CDC42 signaling events;PID Curated;200057 |
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | Sema3A PAK dependent Axon repulsion;PID Reactome;500076 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | role of mal in rho-mediated activation of srf;PID BioCarta;100114 |
Pathway | ccr3 signaling in eosinophils;PID BioCarta;100215 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Sema4D induced cell migration and growth-cone collapse;PID Reactome;500074 |
Pathway | rho cell motility signaling pathway;PID BioCarta;100041 |
Pathway | Caspase cascade in apoptosis;PID Curated;200148 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | RhoA signaling pathway;PID Curated;200007 |
Pathway | CXCR4-mediated signaling events;PID Curated;200083 |
Pathway | RAC1 signaling pathway;PID Curated;200190 |
Pathway | rac1 cell motility signaling pathway;PID BioCarta;100056 |
Pathway | Cytoskeletal regulation by Rho GTPase;PANTHER;P00016 |
Disease | brain aneurysm;GAD |
Disease | Breast cancer;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | Prostate cancer;FunDO |
External Links | |
Links to Entrez Gene | 3984 |
Links to all GeneRIF Items | 3984 |
Links to iHOP | 3984 |
Sequence Information | |
Nucleotide Sequence | >3984 : length: 3398 ACAGGCCCCGCCTCGGTCCGCCCCTCCGCTCGCTCCCCAAGCCGCCGCGGCGCCGAGCCG GTTTCCCCGCCGGTGTCCGAGAGGCGCCCCCGGCCCGGCCCGGCCCGGCCCGCGCCCTCC GCCCCCGCCTCCCCGGGCCGGCGGCGGTGGGCGAGCTCGCGGGCCCGGCCGCCCCCAGCC CCAGCCCCGCCGGGCCCCGCCCCCCGTCGAGTGCATGAGGTTGACGCTACTTTGTTGCAC CTGGAGGGAAGAACGTATGGGAGAGGAAGGAAGCGAGTTGCCCGTGTGTGCAAGCTGCGG CCAGAGGATCTATGATGGCCAGTACCTCCAGGCCCTGAACGCGGACTGGCACGCAGACTG CTTCAGGTGTTGTGACTGCAGTGCCTCCCTGTCGCACCAGTACTATGAGAAGGATGGGCA GCTCTTCTGCAAGAAGGACTACTGGGCCCGCTATGGCGAGTCCTGCCATGGGTGCTCTGA GCAAATCACCAAGGGACTGGTTATGGTGGCTGGGGAGCTGAAGTACCACCCCGAGTGTTT CATCTGCCTCACGTGTGGGACCTTTATCGGTGACGGGGACACCTACACGCTGGTGGAGCA CTCCAAGCTGTACTGCGGGCACTGCTACTACCAGACTGTGGTGACCCCCGTCATCGAGCA GATCCTGCCTGACTCCCCTGGCTCCCACCTGCCCCACACCGTCACCCTGGTGTCCATCCC AGCCTCATCTCATGGCAAGCGTGGACTTTCAGTCTCCATTGACCCCCCGCACGGCCCACC GGGCTGTGGCACCGAGCACTCACACACCGTCCGCGTCCAGGGAGTGGATCCGGGCTGCAT GAGCCCAGATGTGAAGAATTCCATCCACGTCGGAGACCGGATCTTGGAAATCAATGGCAC GCCCATCCGAAATGTGCCCCTGGACGAGATTGACCTGCTGATTCAGGAAACCAGCCGCCT GCTCCAGCTGACCCTCGAGCATGACCCTCACGATACACTGGGCCACGGGCTGGGGCCTGA GACCAGCCCCCTGAGCTCTCCGGCTTATACTCCCAGCGGGGAGGCGGGCAGCTCTGCCCG GCAGAAACCTGTCTTGAGGAGCTGCAGCATCGACAGGTCTCCGGGCGCTGGCTCACTGGG CTCCCCGGCCTCCCAGCGCAAGGACCTGGGTCGCTCTGAGTCCCTCCGCGTAGTCTGCCG GCCACACCGCATCTTCCGGCCGTCGGACCTCATCCACGGGGAGGTGCTGGGCAAGGGCTG CTTCGGCCAGGCTATCAAGGTGACACACCGTGAGACAGGTGAGGTGATGGTGATGAAGGA GCTGATCCGGTTCGACGAGGAGACCCAGAGGACGTTCCTCAAGGAGGTGAAGGTCATGCG ATGCCTGGAACACCCCAACGTGCTCAAGTTCATCGGGGTGCTCTACAAGGACAAGAGGCT CAACTTCATCACTGAGTACATCAAGGGCGGCACGCTCCGGGGCATCATCAAGAGCATGGA CAGCCAGTACCCATGGAGCCAGAGAGTGAGCTTTGCCAAGGACATCGCATCAGGGATGGC CTACCTCCACTCCATGAACATCATCCACCGAGACCTCAACTCCCACAACTGCCTGGTCCG CGAGAACAAGAATGTGGTGGTGGCTGACTTCGGGCTGGCGCGTCTCATGGTGGACGAGAA GACTCAGCCTGAGGGCCTGCGGAGCCTCAAGAAGCCAGACCGCAAGAAGCGCTACACCGT GGTGGGCAACCCCTACTGGATGGCACCTGAGATGATCAACGGCCGCAGCTATGATGAGAA GGTGGATGTGTTCTCCTTTGGGATCGTCCTGTGCGAGATCATCGGGCGGGTGAACGCAGA CCCTGACTACCTGCCCCGCACCATGGACTTTGGCCTCAACGTGCGAGGATTCCTGGACCG CTACTGCCCCCCAAACTGCCCCCCGAGCTTCTTCCCCATCACCGTGCGCTGTTGCGATCT GGACCCCGAGAAGAGGCCATCCTTTGTGAAGCTGGAACACTGGCTGGAGACCCTCCGCAT GCACCTGGCCGGCCACCTGCCACTGGGCCCACAGCTGGAGCAGCTGGACAGAGGTTTCTG GGAGACCTACCGGCGCGGCGAGAGCGGACTGCCTGCCCACCCTGAGGTCCCCGACTGAGC CAGGGCCACTCAGCTGCCCCTGTCCCCACCTCTGGAGAATCCACCCCCACCAGATTCCTC CGCGGGAGGTGGCCCTCAGCTGGGACAGTGGGGACCCAGGCTTCTCCTCAGAGCCAGGCC CTGACTTGCCTTCTCCCACCCCGTGGACCGCTTCCCCTGCCTTCTCTCTGCCGTGGCCCA GAGCCGGCCCAGCTGCACACACACACCATGCTCTCGCCCTGCTGTAACCTCTGTCTTGGC AGGGCTGTCCCCTCTTGCTTCTCCTTGCATGAGCTGGAGGGCCTGTGTGAGTTACGCCCC TTTCCACACGCCGCTGCCCCAGCAACCCTGTTCACGCTCCACCTGTCTGGTCCATAGCTC CCTGGAGGCTGGGCCAGGAGGCAGCCTCCGAACCATGCCCCATATAACGCTTGGGTGCGT GGGAGGGCGCACATCAGGGCAGAGGCCAAGTTCCAGGTGTCTGTGTTCCCAGGAACCAAA TGGGGAGTCTGGGGCCCGTTTTCCCCCCAGGGGGTGTCTAGGTAGCAACAGGTATCGAGG ACTCTCCAAACCCCCAAAGCAGAGAGAGGGCTGATCCCATGGGGCGGAGGTCCCCAGTGG CTGAGCAAACAGCCCCTTCTCTCGCTTTGGGTCTTTTTTTTGTTTCTTTCTTAAAGCCAC TTTAGTGAGAAGCAGGTACCAAGCCTCAGGGTGAAGGGGGTCCCTTGAGGGAGCGTGGAG CTGCGGTGCCCTGGCCGGCGATGGGGAGGAGCCGGCTCCGGCAGTGAGAGGATAGGCACA GTGGACCGGGCAGGTGTCCACCAGCAGCTCAGCCCCTGCAGTCATCTCAGAGCCCCTTCC CGGGCCTCTCCCCCAAGGCTCCCTGCCCCTCCTCATGCCCCTCTGTCCTCTGCGTTTTTT CTGTGTAATCTATTTTTTAAGAAGAGTTTGTATTATTTTTTCATACGGCTGCAGCAGCAG CTGCCAGGGGCTTGGGATTTTATTTTTGTGGCGGGCGGGGGTGGGAGGGCCATTTTGTCA CTTTGCCTCAGTTGAGCATCTAGGAAGTATTAAAACTGTGAAGCTTTCTCAGTGCACTTT GAACCTGGAAAACAATCCCAACAGGCCCGTGGGACCATGACTTAGGGAGGTGGGACCCAC CCACCCCCATCCAGGAACCGTGACGTCCAAGGAACCAAACCCAGACGCAGAACAATAAAA TAAATTCCGTACTCCCCACCCAAAAAAAAAAAAAAAAA |
Protein Sequence | >3984 : length: 647 MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLS HQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGD GDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSV SIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEID LLIQETSRLLQLTLEHDPHDTLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSID RSPGAGSLGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRE TGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGT LRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFG LARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLC EIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL EHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD |