| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3945 |
Name | LDHB |
Synonym | HEL-S-281|LDH-B|LDH-H|LDHBD|TRG-5;lactate dehydrogenase B;LDHB;lactate dehydrogenase B |
Definition | L-lactate dehydrogenase B chain|LDH heart subunit|epididymis secretory protein Li 281|lactate dehydrogenase H chain|renal carcinoma antigen NY-REN-46 |
Position | 12p12.2-p12.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Pyruvate metabolism and Citric Acid (TCA) cycle;Reactome;REACT:1046 |
Pathway | pyruvate fermentation to lactate;BioCyc;PWY-5481 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Pyruvate metabolism;KEGG PATHWAY;hsa00620 |
Pathway | Propanoate metabolism;KEGG PATHWAY;hsa00640 |
Pathway | Cysteine and methionine metabolism;KEGG PATHWAY;hsa00270 |
Pathway | Glycolysis / Gluconeogenesis;KEGG PATHWAY;hsa00010 |
Disease | Brain tumor;FunDO |
Disease | Lactate dehydrogenase-B deficiency;OMIM |
External Links | |
Links to Entrez Gene | 3945 |
Links to all GeneRIF Items | 3945 |
Links to iHOP | 3945 |
Sequence Information | |
Nucleotide Sequence | >3945 : length: 1539 TCCGCACGACTGTTACAGAGGTCTCCAGAGCCTTCTCTCTCCTGGTAGGTTTCGGCTCAG GACCCTGAATCCTGGCCCACAGGCAAGCCTGATGGGACGTGCGGGGTAGTACTTGTATGG GGAGACGCGGGAAGGAGGAAGAAGCACATCTGTCCTCCGCGGCCTTTAGCTCTGAGCATC CGGCCGCGGGCCCTGACTTTGCCGCTCAGTTTGGGGCGCAGGGGGGGCCGTGCCCTGGCG GAGGAGCAGAAGGCAGAGGGTAGCAGCTGCGGCTCAGCGGAGAGACTTGTTGCATTTGCA GCTAAAACCAGGCCCTACTTGTCCTTGTGCAAAATGGCAACTCTTAAGGAAAAACTCATT GCACCAGTTGCGGAAGAAGAGGCAACAGTTCCAAACAATAAGATCACTGTAGTGGGTGTT GGACAAGTTGGTATGGCGTGTGCTATCAGCATTCTGGGAAAGTCTCTGGCTGATGAACTT GCTCTTGTGGATGTTTTGGAAGATAAGCTTAAAGGAGAAATGATGGATCTGCAGCATGGG AGCTTATTTCTTCAGACACCTAAAATTGTGGCAGATAAAGATTATTCTGTGACCGCCAAT TCTAAGATTGTAGTGGTAACTGCAGGAGTCCGTCAGCAAGAAGGGGAGAGTCGGCTCAAT CTGGTGCAGAGAAATGTTAATGTCTTCAAATTCATTATTCCTCAGATCGTCAAGTACAGT CCTGATTGCATCATAATTGTGGTTTCCAACCCAGTGGACATTCTTACGTATGTTACCTGG AAACTAAGTGGATTACCCAAACACCGCGTGATTGGAAGTGGATGTAATCTGGATTCTGCT AGATTTCGCTACCTTATGGCTGAAAAACTTGGCATTCATCCCAGCAGCTGCCATGGATGG ATTTTGGGGGAACATGGCGACTCAAGTGTGGCTGTGTGGAGTGGTGTGAATGTGGCAGGT GTTTCTCTCCAGGAATTGAATCCAGAAATGGGAACTGACAATGATAGTGAAAATTGGAAG GAAGTGCATAAGATGGTGGTTGAAAGTGCCTATGAAGTCATCAAGCTAAAAGGATATACC AACTGGGCTATTGGATTAAGTGTGGCTGATCTTATTGAATCCATGTTGAAAAATCTATCC AGGATTCATCCCGTGTCAACAATGGTAAAGGGGATGTATGGCATTGAGAATGAAGTCTTC CTGAGCCTTCCATGTATCCTCAATGCCCGGGGATTAACCAGCGTTATCAACCAGAAGCTA AAGGATGATGAGGTTGCTCAGCTCAAGAAAAGTGCAGATACCCTGTGGGACATCCAGAAG GACCTAAAAGACCTGTGACTAGTGAGCTCTAGGCTGTAGAAATTTAAAAACTACAATGTG ATTAACTCGAGCCTTTAGTTTTCATCCATGTACATGGATCACAGTTTGCTTTGATCTTCT TCAATATGTGAATTTGGGCTCACAGAATCAAAGCCTATGCTTGGTTTAATGCTTGCAATC TGAGCTCTTGAACAAATAAAATTAACTATTGTAGTGTGC |
Protein Sequence | >3945 : length: 353 MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKVRQTTTKCNMISRIVFYKKIH LKRLRPDKIIVQGYFCLSKFYVNYSHFPTEVLDSKGRKLRESKTFNRLLSFFI |