| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 38 |
Name | ACAT1 |
Synonym | ACAT|MAT|T2|THIL;acetyl-CoA acetyltransferase 1;ACAT1;acetyl-CoA acetyltransferase 1 |
Definition | acetoacetyl Coenzyme A thiolase|acetoacetyl-CoA thiolase|acetyl-CoA acetyltransferase, mitochondrial|acetyl-Coenzyme A acetyltransferase 1|mitochondrial acetoacetyl-CoA thiolase |
Position | 11q22.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | tryptophan degradation III (eukaryotic);BioCyc;TRYPTOPHAN-DEGRADATION-1 |
Pathway | Valine, leucine and isoleucine degradation;KEGG PATHWAY;hsa00280 |
Pathway | superpathway of cholesterol biosynthesis;BioCyc;PWY66-5 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | glutaryl-CoA degradation;BioCyc;PWY-5177 |
Pathway | Butanoate metabolism;KEGG PATHWAY;hsa00650 |
Pathway | ketolysis;BioCyc;PWY66-368 |
Pathway | Pyruvate metabolism;KEGG PATHWAY;hsa00620 |
Pathway | Propanoate metabolism;KEGG PATHWAY;hsa00640 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | isoleucine degradation I;BioCyc;ILEUDEG-PWY |
Pathway | Metabolism of amino acids and derivatives;Reactome;REACT:13 |
Pathway | Synthesis and degradation of ketone bodies;KEGG PATHWAY;hsa00072 |
Pathway | Terpenoid backbone biosynthesis;KEGG PATHWAY;hsa00900 |
Pathway | Fatty acid metabolism;KEGG PATHWAY;hsa00071 |
Pathway | Lysine degradation;KEGG PATHWAY;hsa00310 |
Pathway | ketogenesis;BioCyc;PWY66-367 |
Pathway | mevalonate pathway I;BioCyc;PWY-922 |
Pathway | superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate);BioCyc;PWY-5910 |
Pathway | Tryptophan metabolism;KEGG PATHWAY;hsa00380 |
Disease | Alpha-methylacetoacetic aciduria;OMIM |
Disease | Yersinia infection;FunDO |
External Links | |
Links to Entrez Gene | 38 |
Links to all GeneRIF Items | 38 |
Links to iHOP | 38 |
Sequence Information | |
Nucleotide Sequence | >38 : length: 2149 GGCCGCTAGGGGTGCGGGGTTGGGGAGGAGGCCGCTAGTCTACGCCTGTGGAGCCGATAC TCAGCCCTCTGCGACCATGGCTGTGCTGGCGGCACTTCTGCGCAGCGGCGCCCGCAGCCG CAGCCCCCTGCTCCGGAGGCTGGTGCAGGAAATAAGATATGTGGAACGGAGTTATGTATC AAAACCCACTTTGAAGGAAGTGGTCATAGTAAGTGCTACAAGAACACCCATTGGATCTTT TTTAGGCAGCCTTTCCTTGCTGCCAGCCACTAAGCTTGGTTCCATTGCAATTCAGGGAGC CATTGAAAAGGCAGGGATTCCAAAAGAAGAAGTGAAAGAAGCATACATGGGTAATGTTCT ACAAGGAGGTGAAGGACAAGCTCCTACAAGGCAGGCAGTATTGGGTGCAGGCTTACCTAT TTCTACTCCATGTACCACCATAAACAAAGTTTGTGCTTCAGGAATGAAAGCCATCATGAT GGCCTCTCAAAGTCTTATGTGTGGACATCAGGATGTGATGGTGGCAGGTGGGATGGAGAG CATGTCCAATGTTCCATATGTAATGAACAGAGGATCAACACCATATGGTGGGGTAAAGCT TGAAGATTTGATTGTAAAAGACGGGCTAACTGATGTCTACAATAAAATTCATATGGGCAG CTGTGCTGAGAATACAGCAAAGAAGCTGAATATTGCACGAAATGAACAGGACGCTTATGC TATTAATTCTTATACCAGAAGTAAAGCAGCATGGGAAGCTGGGAAATTTGGAAATGAAGT TATTCCTGTCACAGTTACAGTAAAAGGTCAACCAGATGTAGTGGTGAAAGAAGATGAAGA ATATAAACGTGTTGATTTTAGCAAAGTTCCAAAGCTGAAGACAGTTTTCCAGAAAGAAAA TGGCACAGTAACAGCTGCCAATGCCAGTACACTGAATGATGGAGCAGCTGCTCTGGTTCT CATGACGGCAGATGCAGCGAAGAGGCTCAATGTTACACCACTGGCAAGAATAGTAGCATT TGCTGACGCTGCTGTAGAACCTATTGATTTTCCAATTGCTCCTGTATATGCTGCATCTAT GGTTCTTAAAGATGTGGGATTGAAAAAAGAAGATATTGCAATGTGGGAAGTAAATGAAGC CTTTAGTCTGGTTGTACTAGCAAACATTAAAATGTTGGAGATTGATCCCCAAAAAGTGAA TATCAATGGAGGAGCTGTTTCTCTGGGACATCCAATTGGGATGTCTGGAGCCAGGATTGT TGGTCATTTGACTCATGCCTTGAAGCAAGGAGAATACGGTCTTGCCAGTATTTGCAATGG AGGAGGAGGTGCTTCTGCCATGCTAATTCAGAAGCTGTAGACAACCTCTGCTATTTAAGG AGACAACCCTATGTGACCAGAAGGCCTGCTGTAATCAGTGTGACTACTGTGGGTCAGCTT ATATTCAGATAAGCTGTTTCATTTTTTATTATTTTCTATGTTAACTTTTAAAAATCAAAA TGATGAAATCCCAAAACATTTTGAAATTAAAAATAAATTTCTTCTTCTGCTTTTTTCTTG GTAACCTTGAAAAGTTTGATACATTTTTGCATTCTGAGTCTATACTTATCGAAATATGGT AGAAATACCAATGTGTAATATTAGTGACTTACATAAGTAGCTAGAAGTTTCCATTTGTGA GAACACATTTATATTTTTGAGGATTGTTAAAGGTCAAGTGAATGCTCTTTATAGGTAATT TACATTTAGTAAATTACGGTAAATTAAATTACTTCTCTTTACAGTAAGAGTTGGCTATTC TGGACAAACTAGCAGTGCTTCATATAATCACTCAAACCACAGTGTGTGCAGCAGTACTAG AAACAAGACAGAAGCCCATGTCCTCAGGGTCTAGAGTGGGGGCAATTTCTTATAACCTCA ACATTCAGGGTTGGGGGAGGTCAAGCAGAAAACCCTGGAGTTTGGGCTCTGAATTACTAT AGCAGCATAGAGAGTGGGAAGGGAGGTAGAAACTGATATGCTGAATGGATATATAAAAAA GGGAACAGATCACCACTTCCAATACACGACAATGCCTGTTCTTAAGCAGGACAGACTGTA ACAGAAGTATCTCGCATTGCATTTTATCTGGGAAAAAAAAAAAAAAAAA |
Protein Sequence | >38 : length: 427 MAVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLS LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADA AKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVV LANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGAS AMLIQKL |