| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3685 |
Name | ITGAV |
Synonym | CD51|MSK8|VNRA|VTNR;integrin, alpha V;ITGAV;integrin, alpha V |
Definition | antigen identified by monoclonal antibody L230|integrin alpha-V|integrin alphaVbeta3|integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)|vitronectin receptor subunit alpha |
Position | 2q31-q32 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Small cell lung cancer;KEGG PATHWAY;hsa05222 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Signaling events mediated by VEGFR1 and VEGFR2;PID Curated;200161 |
Pathway | Cell adhesion molecules (CAMs);KEGG PATHWAY;hsa04514 |
Pathway | ECM-receptor interaction;KEGG PATHWAY;hsa04512 |
Pathway | PDGFR-alpha signaling pathway;PID Curated;200140 |
Pathway | Integrin cell surface interactions;Reactome;REACT:13552 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | PECAM1 interactions;PID Reactome;500307 |
Pathway | Integrin cell surface interactions;PID Reactome;500004 |
Pathway | Osteopontin-mediated events;PID Curated;200042 |
Pathway | Nectin adhesion pathway;PID Curated;200053 |
Pathway | Hypertrophic cardiomyopathy (HCM);KEGG PATHWAY;hsa05410 |
Pathway | Signaling events mediated by focal adhesion kinase;PID Curated;200192 |
Pathway | Arrhythmogenic right ventricular cardiomyopathy (ARVC);KEGG PATHWAY;hsa05412 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | phospholipids as signalling intermediaries;PID BioCarta;100183 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Phagosome;KEGG PATHWAY;hsa04145 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Integrins in angiogenesis;PID Curated;200109 |
Pathway | Dilated cardiomyopathy;KEGG PATHWAY;hsa05414 |
Disease | Drug abuse;FunDO |
Disease | Herpes;FunDO |
Disease | Pleural effusion, Malignant;FunDO |
Disease | IMMUNE;GAD |
Disease | Rheumatoid arthritis;FunDO |
Disease | Cancer;FunDO |
Disease | rheumatoid arthritis;GAD |
Disease | Alzheimer's disease;FunDO |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 3685 |
Links to all GeneRIF Items | 3685 |
Links to iHOP | 3685 |
Sequence Information | |
Nucleotide Sequence | >3685 : length: 7053 AGCCTCAGACGCTGCGTGGAGCGGCGGAGCCGGAGGGAAGCAAAGGACCGTCTGCGCTGC TGTCCCCGCCCCGCGCGCTCTGCGCCCCTCGTCCCTGGCGGTCGCTCCGAAGCTCAGCCC TCTTGCCTGCCCCGGAGCTGTCCCGGGCTAGCCGAGAAGAGAGCGGCCGGCAAGTTTGGG CGCGCGCAGGCGGCGGGCCGCGGGCACTGGGCGCCTCGCTGGGGCGGGGGGAGGTGGCTA CCGCTCCCGGCTTGGCGTCCCGCGCGCACTTCGGCGATGGCTTTTCCGCCGCGGCGACGG CTGCGCCTCGGTCCCCGCGGCCTCCCGCTTCTTCTCTCGGGACTCCTGCTACCTCTGTGC CGCGCCTTCAACCTAGACGTGGACAGTCCTGCCGAGTACTCTGGCCCCGAGGGAAGTTAC TTCGGCTTCGCCGTGGATTTCTTCGTGCCCAGCGCGTCTTCCCGGATGTTTCTTCTCGTG GGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAA TGTGACTGGTCTTCTACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGA GATTATGCCAAGGATGATCCATTGGAATTTAAGTCCCATCAGTGGTTTGGAGCATCTGTG AGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATG AAACAGGAGCGAGAGCCTGTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAG TATGCTCCATGTAGATCACAAGATATTGATGCTGATGGACAGGGATTTTGTCAAGGAGGA TTCAGCATTGATTTTACTAAAGCTGACAGAGTACTTCTTGGTGGTCCTGGTAGCTTTTAT TGGCAAGGTCAGCTTATTTCGGATCAAGTGGCAGAAATCGTATCTAAATACGACCCCAAT GTTTACAGCATCAAGTATAATAACCAATTAGCAACTCGGACTGCACAAGCTATTTTTGAT GACAGCTATTTGGGTTATTCTGTGGCTGTCGGAGATTTCAATGGTGATGGCATAGATGAC TTTGTTTCAGGAGTTCCAAGAGCAGCAAGGACTTTGGGAATGGTTTATATTTATGATGGG AAGAACATGTCCTCCTTATACAATTTTACTGGCGAGCAGATGGCTGCATATTTCGGATTT TCTGTAGCTGCCACTGACATTAATGGAGATGATTATGCAGATGTGTTTATTGGAGCACCT CTCTTCATGGATCGTGGCTCTGATGGCAAACTCCAAGAGGTGGGGCAGGTCTCAGTGTCT CTACAGAGAGCTTCAGGAGACTTCCAGACGACAAAGCTGAATGGATTTGAGGTCTTTGCA CGGTTTGGCAGTGCCATAGCTCCTTTGGGAGATCTGGACCAGGATGGTTTCAATGATATT GCAATTGCTGCTCCATATGGGGGTGAAGATAAAAAAGGAATTGTTTATATCTTCAATGGA AGATCAACAGGCTTGAACGCAGTCCCATCTCAAATCCTTGAAGGGCAGTGGGCTGCTCGA AGCATGCCACCAAGCTTTGGCTATTCAATGAAAGGAGCCACAGATATAGACAAAAATGGA TATCCAGACTTAATTGTAGGAGCTTTTGGTGTAGATCGAGCTATCTTATACAGGGCCAGA CCAGTTATCACTGTAAATGCTGGTCTTGAAGTGTACCCTAGCATTTTAAATCAAGACAAT AAAACCTGCTCACTGCCTGGAACAGCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGC TTAAAGGCAGATGGCAAAGGAGTACTTCCCAGGAAACTTAATTTCCAGGTGGAACTTCTT TTGGATAAACTCAAGCAAAAGGGAGCAATTCGACGAGCACTGTTTCTCTACAGCAGGTCC CCAAGTCACTCCAAGAACATGACTATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTG ATAGCGTATCTGCGGGATGAATCTGAATTTAGAGACAAACTCACTCCAATTACTATTTTT ATGGAATATCGGTTGGATTATAGAACAGCTGCTGATACAACAGGCTTGCAACCCATTCTT AACCAGTTCACGCCTGCTAACATTAGTCGACAGGCTCACATTCTACTTGACTGTGGTGAA GACAATGTCTGTAAACCCAAGCTGGAAGTTTCTGTAGATAGTGATCAAAAGAAGATCTAT ATTGGGGATGACAACCCTCTGACATTGATTGTTAAGGCTCAGAATCAAGGAGAAGGTGCC TACGAAGCTGAGCTCATCGTTTCCATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGA AACAATGAAGCCTTAGCAAGACTTTCCTGTGCATTTAAGACAGAAAACCAAACTCGCCAG GTGGTATGTGACCTTGGAAACCCAATGAAGGCTGGAACTCAACTCTTAGCTGGTCTTCGT TTCAGTGTGCACCAGCAGTCAGAGATGGATACTTCTGTGAAATTTGACTTACAAATCCAA AGCTCAAATCTATTTGACAAAGTAAGCCCAGTTGTATCTCACAAAGTTGATCTTGCTGTT TTAGCTGCAGTTGAGATAAGAGGAGTCTCGAGTCCTGATCATATCTTTCTTCCGATTCCA AACTGGGAGCACAAGGAGAACCCTGAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCAC ATCTATGAGCTGAGAAACAATGGTCCAAGTTCATTCAGCAAGGCAATGCTCCATCTTCAG TGGCCTTACAAATATAATAATAACACTCTGTTGTATATCCTTCATTATGATATTGATGGA CCAATGAACTGCACTTCAGATATGGAGATCAACCCTTTGAGAATTAAGATCTCATCTTTG CAAACAACTGAAAAGAATGACACGGTTGCCGGGCAAGGTGAGCGGGACCATCTCATCACT AAGCGGGATCTTGCCCTCAGTGAAGGAGATATTCACACTTTGGGTTGTGGAGTTGCTCAG TGCTTGAAGATTGTCTGCCAAGTTGGGAGATTAGACAGAGGAAAGAGTGCAATCTTGTAC GTAAAGTCATTACTGTGGACTGAGACTTTTATGAATAAAGAAAATCAGAATCATTCCTAT TCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATT GAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCG CCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTG GCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAA GAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACT TAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATA GATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATT GGCATTAACCACAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGA CATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAA GGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAA AATAGTACCTCCTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGT TGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCT TTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAA AGACTTTATAACTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAA ACACATACATGATACCATCCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTT TAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTT ATTACATTTTTAACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAA ATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCA TAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTT TAGTCTGGCTATTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTG AGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGT TAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACT GAGAATGGGTCAAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACC CCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCT AGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATC AGTCTCGGCTGTCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAA AACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAA AAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAG AGGAATATATGATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTA TTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACT GCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTT TTAAAAATGATTGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAG CTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGG ACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAG TATAGATTTTTATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTAC CAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCC ACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACA GTCATTTCTGAAAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGC TTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATT GAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGT TTTGTATAATAGCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATAT GGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCAT GATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACT ACCATATTTGTGATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATC TGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGT AAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTT GAGAAAAATACATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGT AATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGT GTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAA CTCAAGTATTAATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAG TGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGC GATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTA ATGATGAGCTTGGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACC CATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAA TAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATG AAATTACTTAATACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTT TGAACGATAGAAATATGCAGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATAT ATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGT GCAATATAACAATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCC TAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTA TTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTAC CAGTTTTGAAACACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAAT TAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAG ACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAA CTGGTACAGTGTTCTGCTTGATTTACAACATGTAACTTGTGACTGTACAATAAACATAAG CATATGGTACCACAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >3685 : length: 1048 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF FKRVRPPQEEQEREQLQPHENGEGNSET |