| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3575 |
Name | IL7R |
Synonym | CD127|CDW127|IL-7R-alpha|IL7RA|ILRA;interleukin 7 receptor;IL7R;interleukin 7 receptor |
Definition | CD127 antigen|IL-7 receptor subunit alpha|IL-7R subunit alpha|IL-7RA|interleukin 7 receptor alpha chain|interleukin 7 receptor isoform H5-6|interleukin-7 receptor subunit alpha |
Position | 5p13 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Hematopoietic cell lineage;KEGG PATHWAY;hsa04640 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Primary immunodeficiency;KEGG PATHWAY;hsa05340 |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | Diabetes mellitus;FunDO |
Disease | type 1 diabetes;GAD |
Disease | IMMUNE;GAD |
Disease | Immune system diseases;KEGG DISEASE |
Disease | T-B+ Severe combined immunodeficiencies;KEGG DISEASE;H00091 |
Disease | Multiple sclerosis;FunDO |
Disease | Severe combined immunodeficiency, T-cell negative, B-cell/natural killer cell-positive type;OMIM |
Disease | Congenital abnormality;FunDO |
Disease | Cancer;FunDO |
Disease | Multiple sclerosis;NHGRI |
Disease | multiple sclerosis;GAD |
Disease | allergy;GAD |
Disease | HIV infection;FunDO |
Disease | Type 1 diabetes;NHGRI |
External Links | |
Links to Entrez Gene | 3575 |
Links to all GeneRIF Items | 3575 |
Links to iHOP | 3575 |
Sequence Information | |
Nucleotide Sequence | >3575 : length: 4617 ATCTAAGCTTCTCTGTCTTCCTCCCTCCCTCCCTTCCTCTTACTCTCATTCATTTCATAC ACACTGGCTCACACATCTACTCTCTCTCTCTATCTCTCTCAGAATGACAATTCTAGGTAC AACTTTTGGCATGGTTTTTTCTTTACTTCAAGTCGTTTCTGGAGAAAGTGGCTATGCTCA AAATGGAGACTTGGAAGATGCAGAACTGGATGACTACTCATTCTCATGCTATAGCCAGTT GGAAGTGAATGGATCGCAGCACTCACTGACCTGTGCTTTTGAGGACCCAGATGTCAACAT CACCAATCTGGAATTTGAAATATGTGGGGCCCTCGTGGAGGTAAAGTGCCTGAATTTCAG GAAACTACAAGAGATATATTTCATCGAGACAAAGAAATTCTTACTGATTGGAAAGAGCAA TATATGTGTGAAGGTTGGAGAAAAGAGTCTAACCTGCAAAAAAATAGACCTAACCACTAT AGTTAAACCTGAGGCTCCTTTTGACCTGAGTGTCGTCTATCGGGAAGGAGCCAATGACTT TGTGGTGACATTTAATACATCACACTTGCAAAAGAAGTATGTAAAAGTTTTAATGCACGA TGTAGCTTACCGCCAGGAAAAGGATGAAAACAAATGGACGCATGTGAATTTATCCAGCAC AAAGCTGACACTCCTGCAGAGAAAGCTCCAACCGGCAGCAATGTATGAGATTAAAGTTCG ATCCATCCCTGATCACTATTTTAAAGGCTTCTGGAGTGAATGGAGTCCAAGTTATTACTT CAGAACTCCAGAGATCAATAATAGCTCAGGGGAGATGGATCCTATCTTACTAACCATCAG CATTTTGAGTTTTTTCTCTGTCGCTCTGTTGGTCATCTTGGCCTGTGTGTTATGGAAAAA AAGGATTAAGCCTATCGTATGGCCCAGTCTCCCCGATCATAAGAAGACTCTGGAACATCT TTGTAAGAAACCAAGAAAAAATTTAAATGTGAGTTTCAATCCTGAAAGTTTCCTGGACTG CCAGATTCATAGGGTGGATGACATTCAAGCTAGAGATGAAGTGGAAGGTTTTCTGCAAGA TACGTTTCCTCAGCAACTAGAAGAATCTGAGAAGCAGAGGCTTGGAGGGGATGTGCAGAG CCCCAACTGCCCATCTGAGGATGTAGTCATCACTCCAGAAAGCTTTGGAAGAGATTCATC CCTCACATGCCTGGCTGGGAATGTCAGTGCATGTGACGCCCCTATTCTCTCCTCTTCCAG GTCCCTAGACTGCAGGGAGAGTGGCAAGAATGGGCCTCATGTGTACCAGGACCTCCTGCT TAGCCTTGGGACTACAAACAGCACGCTGCCCCCTCCATTTTCTCTCCAATCTGGAATCCT GACATTGAACCCAGTTGCTCAGGGTCAGCCCATTCTTACTTCCCTGGGATCAAATCAAGA AGAAGCATATGTCACCATGTCCAGCTTCTACCAAAACCAGTGAAGTGTAAGAAACCCAGA CTGAACTTACCGTGAGCGACAAAGATGATTTAAAAGGGAAGTCTAGAGTTCCTAGTCTCC CTCACAGCACAGAGAAGACAAAATTAGCAAAACCCCACTACACAGTCTGCAAGATTCTGA AACATTGCTTTGACCACTCTTCCTGAGTTCAGTGGCACTCAACATGAGTCAAGAGCATCC TGCTTCTACCATGTGGATTTGGTCACAAGGTTTAAGGTGACCCAATGATTCAGCTATTTA AAAAAAAAAGAGGAAAGAATGAAAGAGTAAAGGAAATGATTGAGGAGTGAGGAAGGCAGG AAGAGAGCATGAGAGGAAAGAAAGAAAGGAAAATAAAAAATGATAGTTGCCATTATTAGG ATTTAATATATATCCAGTGCTTTGCAAGTGCTCTGCGCACCTTGTCTCACTCCATCCTGA CAATAATCCTGGGAGGTGTGTGCAATTACTACGACTACTCTCTTTTTTATAGATCATTAA ATTCAGAACTAAGGAGTTAAGTAACTTGTCCAAGTTGTTCACACAGTGAAGGGAGGGGCC AAGATATGATGGCTGGGAGTCTAATTGCAGTTCCCTGAGCCATGTGCCTTTCTCTTCACT GAGGACTGCCCCATTCTTGAGTGCCAAACGTCACTAGTAACAGGGTGTGCCTAGATAATT TATGATCCAAACTGAGTCAGTTTGGAAAGTGAAAGGGAAACTTACATATAATCCCTCCGG GACAATGAGCAAAAACTAGGACTGTCCCCAGACAAATGTGAACATACATATCATCACTTA AATTAAAATGGCTATGAGAAAGAAAGAGGGGGAGAAACAGTCTTGCGGGTGTGAAGTCCC ATGACCAGCCATGTCAAAAGAAGGTAAAGAAGTCAAGAAAAAGCCATGAAGCCCATTTGG TTTCATTTTTCTGAAAATAGGCTCAAGAGGGAATAAATTAGAAACTCACAATTTCTCTTG TTTGTTACCAAGACAGTGATTCTCTTGCTGCTACCACCCAACTGCATCCGTCCATGATCT CAGAGGAAACTGTCGCTGACCCTGGACATGGGTACGTTTGACGAGTGAGAGGAGGCATGA CCCCTCCCATGTGTATAGACACTACCCCAACCTAAATTCATCCCTAAATTGTCCCAAGTT CTCCAGCAATAGAGGCTGCCACAAACTTCAGGGAGAAAGAGTTACAAGTACATGCAATGA GTGAACTGACTGTGGCTACAATCTTGAAGATATACGGAAGAGACGTATTATTAATGCTTG ACATATATCATCTTGCCTTTCTTGGTCTAGACTGACTTCTAATGACTAACTCAAAGTCAA GGCAACTGAGTAATGTCAGCTCAGCAAAGTGCAGCAAACCCATCTCCCACAGGCCTCCAA ACCCTGGCTGTTCACAGAACCACAAAGGGCAGATGCTGCACAGAAAACTAGAGAAGGGGT CATAGGTTCATGGTTTTGTTTGAGATTTGTTGCTACTGTTTTTCTGTTTTGAATTTTCTT CTTTGTTCTGTTTTTACTTTATTTAGGGGGACTAGGTGTTTCTGATATTTTAGTTTTCTT GTTTGTTTTGTTTTGTGTTGTCTGTGAATGGGGTTTTAACTGTGGATGAATGGACCTTAT CTGTTGGCTTAAAGGACTGGTAAGATCAGACCATCTTATTCTTCAGGTGAATGTTTTACT TTCCAAAGTGCTCTCCTCTGCACCAGCAGTAATAAATACAATGCCATAATCCCTTAGGTT TGCCTAGTGCTTTTGCAATTTTCAAAGCACTTCCATAAGCATTCCTTCCACCTCCTTGAT AGGCATTTATGGAAAGCCTGCTACATGTCAATCATACTGTTAGGCACAGGGGACCTAAAG ACACATAAAAGGATGGCATTCTGCCTCATAAATTGCAAAACCTAATGAAAGTGACTGCTT GGTAAACAAATTATTATTATATTATAAAATGCTATAAAAGAGCCATATTGAAAGTGCCCT GTTGGAGACAGGGCAAATGCCACAAAAATGATGTAAATTTACATGGAGGAAAAGTAGAAT CTGCCTGGTTTGTAGGCAGCAGAAGACATTTTTCATCAGTGGGCAGGTGTTCTTTACCTT TTGTAGAAATGGGAGTCAAGTCTCAAATAGGAGGCTCCACAAAATCTCATGCCAGGTCTC TGATACCTTATTCACAGAAGTTCTTTGAAGTATTTATTGTTATTTTCTTTGACTTATGGG AAAACTGGGACACAGGAAGACAGGTAAATTACCCAACCTCACACGTTAAGTCAGAACTGG GAGCCATAATTTTGTATCCCTGGTATAAATAGACAATCTCTTGAAGAAATGAAGAGATGA CCATAGAAAAACATCGAGATATCTCCAGCTCTAAAATCCTTTGTTTCAATGTTGTTTGGC ATATGTTATCTTTGGAATTTAGTGTCTGAGCCTCTGTCTGTTACTGTAGTATTTAAAATG CATGTATTATAATCATATAATCATAACTGCTGTTAATTCTTGATTATATACCTAGGGACA ATGTGTAATGTAAGATTACTAATTGGTTCTGCCCAATCTCCTTTCAGATTTTATTAGGAA AAAAAAATAAACCTCCTGATCGGAGACAATGTATTAATCAGAAGTGTAAACTGCCAGTTC TATATAGCATGAAATGAAAAGACAGCTAATTTGGTCCAACAAACATGACTGGGTCTAGGG CACCCAGGCTGATTCAGCTGATTTCCTACCAGCCTTTGCCTCTTCCTTCAATGTGGTTTC CATGGGAATTTGCTTCAGAAAAGCCAAGTATGGGCTGTTCAGAGGTGCACACCTGCATTT TCTTAGCTCTTCTAGAGGGGCTAAGAGACTTGGTACGGGCCAGGAAGAATATGTGGCAGA GCTCCTGGAAATGATGCAGATTAGGTGGCATTTTTGTCAGCTCTGTGGTTTATTGTTGGG ACTATTCTTTAAAATATCCATTGTTCACTACAGTGAAGATCTCTGATTTAACCGTGTACT ATCCACATGCATTACAAACATTTCGCAGAGCTGCTTAGTATATAAGCGTACAATGTATGT AATAACCATCTCATATTTAATTAAATGGTATAGAAGAACAAAAAAAAAAAAAAAAAA |
Protein Sequence | >3575 : length: 459 MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYSQLEVNGSQHSLTCAFE DPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKK IDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTH VNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSSGEMDP ILLTISILSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNVSFNP ESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPNCPSEDVVITPES FGRDSSLTCLAGNVSACDAPILSSSRSLDCRESGKNGPHVYQDLLLSLGTTNSTLPPPFS LQSGILTLNPVAQGQPILTSLGSNQEEAYVTMSSFYQNQ |