| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3394 |
Name | IRF8 |
Synonym | H-ICSBP|ICSBP|ICSBP1|IMD32A|IMD32B|IRF-8;interferon regulatory factor 8;IRF8;interferon regulatory factor 8 |
Definition | interferon consensus sequence binding protein 1 |
Position | 16q24.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Pathway | GMCSF-mediated signaling events;PID Curated;200015 |
Disease | Carcinoma;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | multiple sclerosis;GAD |
Disease | IMMUNE;GAD |
Disease | Infection;FunDO |
Disease | Chronic lymphocytic leukemia;NHGRI |
Disease | Chronic lymphocytic leukemia;GAD |
Disease | Lymphoma;FunDO |
Disease | Leukemia;FunDO |
Disease | CANCER;GAD |
Disease | Multiple sclerosis;NHGRI |
External Links | |
Links to Entrez Gene | 3394 |
Links to all GeneRIF Items | 3394 |
Links to iHOP | 3394 |
Sequence Information | |
Nucleotide Sequence | >3394 : length: 2678 AGCGCGGCAGCAAGCGTGGGAACGCGGGCGGCGAGACGGCGGCAGGACGGCGGCAGGATG TGTGACCGGAATGGTGGTCGGCGGCTTCGACAGTGGCTGATCGAGCAGATTGACAGTAGC ATGTATCCAGGACTGATTTGGGAGAATGAGGAGAAGAGCATGTTCCGGATCCCTTGGAAA CACGCTGGCAAGCAAGATTATAATCAGGAAGTGGATGCCTCCATTTTTAAGGCCTGGGCA GTTTTTAAAGGGAAGTTTAAAGAAGGGGACAAAGCTGAACCAGCCACTTGGAAGACGAGG TTACGCTGTGCTTTGAATAAGAGCCCAGATTTTGAGGAAGTGACGGACCGGTCCCAACTG GACATTTCCGAGCCATACAAAGTTTACCGAATTGTTCCTGAGGAAGAGCAAAAATGCAAA CTAGGCGTGGCAACTGCTGGCTGCGTGAATGAAGTTACAGAGATGGAGTGCGGTCGCTCT GAAATCGACGAGCTGATCAAGGAGCCTTCTGTGGACGATTACATGGGGATGATCAAAAGG AGCCCTTCCCCGCCGGAGGCCTGTCGGAGTCAGCTCCTTCCAGACTGGTGGGCGCAGCAG CCCAGCACAGGCGTGCCGCTGGTGACGGGGTACACCACCTACGACGCGCACCATTCAGCA TTCTCCCAGATGGTGATCAGCTTCTACTATGGGGGCAAGCTGGTGGGCCAGGCCACCACC ACCTGCCCCGAGGGCTGCCGCCTGTCCCTGAGCCAGCCTGGGCTGCCCGGCACCAAGCTG TATGGGCCCGAGGGCCTGGAGCTGGTGCGCTTCCCGCCGGCCGACGCCATCCCCAGCGAG CGACAGAGGCAGGTGACGCGGAAGCTGTTCGGGCACCTGGAGCGCGGGGTGCTGCTGCAC AGCAGCCGGCAGGGCGTGTTCGTCAAGCGGCTGTGCCAGGGCCGCGTGTTCTGCAGCGGC AACGCCGTGGTGTGCAAAGGCAGGCCCAACAAGCTGGAGCGTGATGAGGTGGTCCAGGTC TTCGACACCAGCCAGTTCTTCCGAGAGCTGCAGCAGTTCTATAACAGCCAGGGCCGGCTT CCTGACGGCAGGGTGGTGCTGTGCTTTGGGGAAGAGTTTCCGGATATGGCCCCCTTGCGC TCCAAACTCATTCTCGTGCAGATTGAGCAGCTGTATGTCCGGCAACTGGCAGAAGAGGCT GGGAAGAGCTGTGGAGCCGGCTCTGTGATGCAGGCCCCCGAGGAGCCGCCGCCAGACCAG GTCTTCCGGATGTTTCCAGATATTTGTGCCTCACACCAGAGATCATTTTTCAGAGAAAAC CAACAGATCACCGTCTAAGTGCGTCGCTTGGGCGCCCCACCCCGTCTGCGTCCTGCATCC ATCTCCCTGTTACAGTGGCCCGCATCATGATTAAAGAATGTGGATCCCTCTGTCTGGGGT GGGATGCCTTACTTTGCACTTAATTTAATAAGGGCATTCTCGGAGGAGTAGACGTTTAAT ACGAAGTGGCGGCATAGCCCTGCCGAGATGTCGGTGATGGCCTGGATGCTGTAACCACAA CCTGTGGCTAAAAATTTTATTTTCTATCCTTTACCCGTCATTATCATTAGTTGCTATGAT TCTTTCTGCATTTTCGGTTAACTATCATTTCCAAAGACTTGTCATTCAGTAATATTAGCA GATAGCTGCTTCGATAAAGGAATTTGGAGTTTAAAAATCAACTTGTGAAAACAAGGTTGT TTTTGTCTTTATCGTTTGTTAGAGTTATAGATTTATGATTTCATAGGCTTGATTCTATGT GAAATATCTTTTTACTTTTATGCATTTTAATAAGATTTAAAAATATTTAGATTAAAGCCC CCTTTAATGAGTACAAGAAAAACTCTTGGCTTGTTAGAAGAAAGTATATTCTTTCTAGAA TTTGGTGCAGGAATATGTGTTCATATCCAGGCAAACGGGTGTGTTTTTATCTTCAGACAA TGAAACCTTCTCCTCTGGGGCTTTGTTGCCAGGAAGATTAGAACTAAATTTATTTTTTTC ATTTCTGTCATGAAATCATTCCAGATACCTCTTTTCTTCTTTCCAAATGGTTTTCACATG TGTTTGAAATATTTGTACTTCGAATTGTCGGATTTTCCATGTCCTCCTTTCTCCTTTGTG CCCAGCCTGAGTCAGCACCAATCCCGCATTCAGAACCTCCCAGTGAAAGGGCAGCCTTCA TTTTGAGAAGGTGGAAGGTGTTAGGGTTTGGGAGACAGCTCATCCAATCTCCCAAGTCTC ATGGTGGATTTGTGACTGTGAGAGTTTCCGGTTTAAAATCTGAAAAGCCAGATATGCCTG TTTCCTTTTCCCAGCACCATGCCTGTGGAGGGGACAGTCAGACCCAGAGGTCCTTTACGT GTGGATGGAGTTCACAGGCGAATAGAGGAGAGGACCAGGGGACGTGGCTTGTCCCTTTTG TCCAACAAAGCATTATATTTTTAAGAATGGCAGACCTGTTTGCTGAAGTGTTCATAAGAT AACAATAGGCTTGAATCTCCAATTCAAATGAATGTCAAAGCACATATCTTTAATATGCTG AATGAATATTTATTTTTGTATCCATTAAAACAGTATATTGATCTCTTTTATTCTTTATTA AAATAAAATGCTCTTTTTTAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >3394 : length: 426 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW AVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKC KLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQ QPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTK LYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCS GNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPL RSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRE NQQITV |