| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3133 |
Name | HLA-E |
Synonym | EA1.2|EA2.1|HLA-6.2|MHC|QA1;major histocompatibility complex, class I, E;HLA-E;major histocompatibility complex, class I, E |
Definition | HLA class I histocompatibility antigen, E alpha chain|HLA class I histocompatibility antigen, alpha chain E|MHC HLA-E alpha-1|MHC HLA-E alpha-2.1|MHC class I antigen E|lymphocyte antigen |
Position | 6p21.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Antigen processing and presentation;KEGG PATHWAY;hsa04612 |
Pathway | Type I diabetes mellitus;KEGG PATHWAY;hsa04940 |
Pathway | Allograft rejection;KEGG PATHWAY;hsa05330 |
Pathway | Viral myocarditis;KEGG PATHWAY;hsa05416 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Cell adhesion molecules (CAMs);KEGG PATHWAY;hsa04514 |
Pathway | Graft-versus-host disease;KEGG PATHWAY;hsa05332 |
Pathway | Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650 |
Pathway | Phagosome;KEGG PATHWAY;hsa04145 |
Pathway | Autoimmune thyroid disease;KEGG PATHWAY;hsa05320 |
Disease | nasopharyngeal cancer;GAD |
Disease | Type 1 diabetes;NHGRI |
Disease | Plasma eosinophil count;NHGRI |
Disease | IMMUNE;GAD |
Disease | Psoriasis;NHGRI |
Disease | HIV;GAD |
Disease | bone marrow transplantation;GAD |
Disease | Schizophrenia;NHGRI |
Disease | graft-versus-host disease;GAD |
Disease | CANCER;GAD |
Disease | Rheumatoid arthritis;NHGRI |
Disease | Ankylosing spondylitis;NHGRI |
Disease | Ulcerative colitis;NHGRI |
Disease | INFECTION;GAD |
Disease | Cognitive test performance;NHGRI |
Disease | Bone mineral density (spine);NHGRI |
External Links | |
Links to Entrez Gene | 3133 |
Links to all GeneRIF Items | 3133 |
Links to iHOP | 3133 |
Sequence Information | |
Nucleotide Sequence | >3133 : length: 2679 GCAGACTCAGTTCTCATTCCCAATGGGTGTCGGGTTTCTAGAGAAGCCAATCAGCGTCGC CACGACTCCCGACTATAAAGTCCCCATCCGGACTCAAGAAGTTCTCAGGACTCAGAGGCT GGGATCATGGTAGATGGAACCCTCCTTTTACTCCTCTCGGAGGCCCTGGCCCTTACCCAG ACCTGGGCGGGCTCCCACTCCTTGAAGTATTTCCACACTTCCGTGTCCCGGCCCGGCCGC GGGGAGCCCCGCTTCATCTCTGTGGGCTACGTGGACGACACCCAGTTCGTGCGCTTCGAC AACGACGCCGCGAGTCCGAGGATGGTGCCGCGGGCGCCGTGGATGGAGCAGGAGGGGTCA GAGTATTGGGACCGGGAGACACGGAGCGCCAGGGACACCGCACAGATTTTCCGAGTGAAT CTGCGGACGCTGCGCGGCTACTACAATCAGAGCGAGGCCGGGTCTCACACCCTGCAGTGG ATGCATGGCTGCGAGCTGGGGCCCGACGGGCGCTTCCTCCGCGGGTATGAACAGTTCGCC TACGACGGCAAGGATTATCTCACCCTGAATGAGGACCTGCGCTCCTGGACCGCGGTGGAC ACGGCGGCTCAGATCTCCGAGCAAAAGTCAAATGATGCCTCTGAGGCGGAGCACCAGAGA GCCTACCTGGAAGACACATGCGTGGAGTGGCTCCACAAATACCTGGAGAAGGGGAAGGAG ACGCTGCTTCACCTGGAGCCCCCAAAGACACACGTGACTCACCACCCCATCTCTGACCAT GAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGG CAGCAGGATGGGGAGGGCCATACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCAGGG GATGGAACCTTCCAGAAGTGGGCAGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATAC ACGTGCCATGTGCAGCATGAGGGGCTACCCGAGCCCGTCACCCTGAGATGGAAGCCGGCT TCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGATCTGTG GTCTCTGGAGCTGTGGTTGCTGCTGTGATATGGAGGAAGAAGAGCTCAGGTGGAAAAGGA GGGAGCTACTCTAAGGCTGAGTGGAGCGACAGTGCCCAGGGGTCTGAGTCTCACAGCTTG TAAAGCCTGAGACAGCTGCCTTGTGTGCGACTGAGATGCACAGCTGCCTTGTGTGCGACT GAGATGCAGGATTTCCTCACGCCTCCCCTATGTGTCTTAGGGGACTCTGGCTTCTCTTTT TGCAAGGGCCTCTGAATCTGTCTGTGTCCCTGTTAGCACAATGTGAGGAGGTAGAGAAAC AGTCCACCTCTGTGTCTACCATGACCCCCTTCCTCACACTGACCTGTGTTCCTTCCCTGT TCTCTTTTCTATTAAAAATAAGAACCTGGGCAGAGTGCGGCAGCTCATGCCTGTAATCCC AGCACTTAGGGAGGCCGAGGAGGGCAGATCACGAGGTCAGGAGATCGAAACCATCCTGGC TAACACGGTGAAACCCCGTCTCTACTAAAAAATACAAAAAATTAGCTGGGCGCAGAGGCA CGGGCCTGTAGTCCCAGCTACTCAGGAGGCGGAGGCAGGAGAATGGCGTCAACCCGGGAG GCGGAGGTTGCAGTGAGCCAGGATTGTGCGACTGCACTCCAGCCTGGGTGACAGGGTGAA ACGCCATCTCAAAAAATAAAAATTGAAAAATAAAAAAAGAACCTGGATCTCAATTTAATT TTTCATATTCTTGCAATGAAATGGACTTGAGGAAGCTAAGATCATAGCTAGAAATACAGA TAATTCCACAGCACATCTCTAGCAAATTTAGCCTATTCCTATTCTCTAGCCTATTCCTTA CCACCTGTAATCTTGACCATATACCTTGGAGTTGAATATTGTTTTCATACTGCTGTGGTT TGAATGTTCCCTCCAACACTCATGTTGAGACTTAATCCCTAATGTGGCAATACTGAAAGG TGGGGCCTTTGAGATGTGATTGGATCGTAAGGCTGTGCCTTCATTCATGGGTTAATGGAT TAATGGGTTATCACAGGAATGGGACTGGTGGCTTTATAAGAAGAGGAAAAGAGAACTGAG CTAGCATGCCCAGCCCACAGAGAGCCTCCACTAGAGTGATGCTAAGTGGAAATGTGAGGT GCAGCTGCCACAGAGGGCCCCCACCAGGGAAATGTCTAGTGTCTAGTGGATCCAGGCCAC AGGAGAGAGTGCCTTGTGGAGCGCTGGGAGCAGGACCTGACCACCACCAGGACCCCAGAA CTGTGGAGTCAGTGGCAGCATGCAGCGCCCCCTTGGGAAAGCTTTAGGCACCAGCCTGCA ACCCATTCGAGCAGCCACGTAGGCTGCACCCAGCAAAGCCACAGGCACGGGGCTACCTGA GGCCTTGGGGGCCCAATCCCTGCTCCAGTGTGTCCGTGAGGCAGCACACGAAGTCAAAAG AGATTATTCTCTTCCCACAGATACCTTTTCTCTCCCATGACCCTTTAACAGCATCTGCTT CATTCCCCTCACCTTCCCAGGCTGATCTGAGGTAAACTTTGAAGTAAAATAAAAGCTGTG TTTGAGCATCATTTGTATTTCAAAAAAAAAAAAAAAAAA |
Protein Sequence | >3133 : length: 358 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL |