| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3084 |
Name | NRG1 |
Synonym | ARIA|GGF|GGF2|HGL|HRG|HRG1|HRGA|MST131|MSTP131|NDF|NRG1-IT2|SMDF;neuregulin 1;NRG1;neuregulin 1 |
Definition | glial growth factor|heregulin, alpha (45kD, ERBB2 p185-activator)|neu differentiation factor|pro-NRG1|pro-neuregulin-1, membrane-bound isoform|sensory and motor neuron derived factor |
Position | 8p12 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | ErbB receptor signaling network;PID Curated;200136 |
Pathway | Glypican 1 network;PID Curated;200021 |
Pathway | ErbB signaling pathway;KEGG PATHWAY;hsa04012 |
Pathway | ErbB4 signaling events;PID Curated;200009 |
Pathway | ErbB2/ErbB3 signaling events;PID Curated;200119 |
Disease | Hirschsprung's disease;NHGRI |
Disease | PSYCH;GAD |
Disease | hip geometry;GAD |
Disease | Hip geometry;NHGRI |
Disease | CARDIOVASCULAR;GAD |
Disease | schizophrenia;GAD |
Disease | psychoses schizophrenia;GAD |
Disease | METABOLIC;GAD |
Disease | Schizophrenia, susceptibility to;OMIM |
Disease | Atherosclerosis;GAD |
Disease | Hirschsprung's disease;GAD |
External Links | |
Links to Entrez Gene | 3084 |
Links to all GeneRIF Items | 3084 |
Links to iHOP | 3084 |
Sequence Information | |
Nucleotide Sequence | >3084 : length: 6771 GGCTTAACTGATGCCTGCCTGCCTCTCTTTGATTTGATGGCCTTTATTCCTTCTAATTGG ATAAAATAGGAAGTCACTGGCAGTCCTGTGTGGCTGGGGATACTGATTTTACTCAGACCA GCCTGCAGCTCTAGAGTGTGGGTAGAGAGCGGGGAGTGGGGGTTGGGAGAGGGGGAGGAA AGAGAGAGAGGAGAGAGGACGGGCTTGGATGAAGAAGGGAAAGAAAGAGAAAGAGACTGA AGCAGAGAAGAGCCGCAGAGGAAGAAAGTGAATGAGCACTCAAGAAGGACAAAGAGGAGT AGTCGGGGGTGGGGTGGAGGCAGGGCGGGGAAGGGAGTGACCGCCCCTCCTGGCTGCACT CTTGCCTCCGGAGCCCTCTGATCCTGTTTGCAGTGATGCTCCGAGGGCAGGCACCTGCTG CTCTGTAATGATTCAGCCCCTTTCAGCCGTCGTCGCGTTAACACAACAGGATGCTGTTGC TATTGTCACTACTGCCTCTCCTGCCGCCGCTGCTGCTGCCGCCGCCGCCACCGCCGCTGG TCCTCCTTCTGCTTTTACTTCTCCTGCATGACAGTTGTTTTCTTCATCTGAGCAGACACC AGCTTCAGATGCTCGAGGTGAGAAACATGCCTTTCAGTTTGGGCTACTGGTTTACTTAAT TAATCAGCCGGCAGCTCCGTCGATCTATTTTCGTCCCTGTCCTCTTGACGAGCCCGGGAT GGTTTGGAGTAGCATTTAAAAGAACTAGAAAAGTGGCCCAGAAACAGCAGCTTAAAGAAT TATTACGATATACTTTGATTTTGTAGTTGCTAGGAGCTTTTCTTCCCCCCTTGCATCTTT CTGAACTCTTCTTGATTTTAATAATGGCCTTGGACTTGGACGATTTATCGATTTCCCCCT GTAAGATGCTGTATCATTTGGTTGGGGGGGCCTCTGCGTGGTAATGGACCGTGAGAGCGG CCAGGCCTTCTTCTGGAGGTGAGCCGATGGAGATTTATTCCCCAGACATGTCTGAGGTCG CCGCCGAGAGGTCCTCCAGCCCCTCCACTCAGCTGAGTGCAGACCCATCTCTTGATGGGC TTCCGGCAGCAGAAGACATGCCAGAGCCCCAGACTGAAGATGGGAGAACCCCTGGACTCG TGGGCCTGGCCGTGCCCTGCTGTGCGTGCCTAGAAGCTGAGCGCCTGAGAGGTTGCCTCA ACTCAGAGAAAATCTGCATTGTCCCCATCCTGGCTTGCCTGGTCAGCCTCTGCCTCTGCA TCGCCGGCCTCAAGTGGGTATTTGTGGACAAGATCTTTGAATATGACTCTCCTACTCACC TTGACCCTGGGGGGTTAGGCCAGGACCCTATTATTTCTCTGGACGCAACTGCTGCCTCAG CTGTGTGGGTGTCGTCTGAGGCATACACTTCACCTGTCTCTAGGGCTCAATCTGAAAGTG AGGTTCAAGTTACAGTGCAAGGTGACAAGGCTGTTGTCTCCTTTGAACCATCAGCGGCAC CGACACCGAAGAATCGTATTTTTGCCTTTTCTTTCTTGCCGTCCACTGCGCCATCCTTCC CTTCACCCACCCGGAACCCTGAGGTGAGAACGCCCAAGTCAGCAACTCAGCCACAAACAA CAGAAACTAATCTCCAAACTGCTCCTAAACTTTCTACATCTACATCCACCACTGGGACAA GCCATCTTGTAAAATGTGCGGAGAAGGAGAAAACTTTCTGTGTGAATGGAGGGGAGTGCT TCATGGTGAAAGACCTTTCAAACCCCTCGAGATACTTGTGCAAGTGCCAACCTGGATTCA CTGGAGCAAGATGTACTGAGAATGTGCCCATGAAAGTCCAAAACCAAGAAAAGGCGGAGG AGCTGTACCAGAAGAGAGTGCTGACCATAACCGGCATCTGCATCGCCCTCCTTGTGGTCG GCATCATGTGTGTGGTGGCCTACTGCAAAACCAAGAAACAGCGGAAAAAGCTGCATGACC GTCTTCGGCAGAGCCTTCGGTCTGAACGAAACAATATGATGAACATTGCCAATGGGCCTC ACCATCCTAACCCACCCCCCGAGAATGTCCAGCTGGTGAATCAATACGTATCTAAAAACG TCATCTCCAGTGAGCATATTGTTGAGAGAGAAGCAGAGACATCCTTTTCCACCAGTCACT ATACTTCCACAGCCCATCACTCCACTACTGTCACCCAGACTCCTAGCCACAGCTGGAGCA ACGGACACACTGAAAGCATCCTTTCCGAAAGCCACTCTGTAATCGTGATGTCATCCGTAG AAAACAGTAGGCACAGCAGCCCAACTGGGGGCCCAAGAGGACGTCTTAATGGCACAGGAG GCCCTCGTGAATGTAACAGCTTCCTCAGGCATGCCAGAGAAACCCCTGATTCCTACCGAG ACTCTCCTCATAGTGAAAGACATAACCTTATAGCTGAGCTAAGGAGAAACAAGGCACACA GATCCAAATGCATGCAGATCCAGCTATCAGCAACTCATCTTAGATCTTCTTCCATTCCCC ATTTGGGCTTCATTCTCTAAGACCCCTTGGCCTTTAGGAAGGTATGTGTCAGCCATGACC ACCCCGGCTCGTATGTCACCTGTAGATTTCCACACGCCAAGCTCCCCCAAATCGCCCCCT TCGGAAATGTCTCCACCCGTGTCCAGCATGACGGTGTCCATGCCTTCCATGGCGGTCAGC CCCTTCATGGAAGAAGAGAGACCTCTACTTCTCGTGACACCACCAAGGCTGCGGGAGAAG AAGTTTGACCATCACCCTCAGCAGTTCAGCTCCTTCCACCACAACCCCGCGCATGACAGT AACAGCCTCCCTGCTAGCCCCTTGAGGATAGTGGAGGATGAGGAGTATGAAACGACCCAA GAGTACGAGCCAGCCCAAGAGCCTGTTAAGAAACTCGCCAATAGCCGGCGGGCCAAAAGA ACCAAGCCCAATGGCCACATTGCTAACAGATTGGAAGTGGACAGCAACACAAGCTCCCAG AGCAGTAACTCAGAGAGTGAAACAGAAGATGAAAGAGTAGGTGAAGATACGCCTTTCCTG GGCATACAGAACCCCCTGGCAGCCAGTCTTGAGGCAACACCTGCCTTCCGCCTGGCTGAC AGCAGGACTAACCCAGCAGGCCGCTTCTCGACACAGGAAGAAATCCAGGCCAGGCTGTCT AGTGTAATTGCTAACCAAGACCCTATTGCTGTATAAAACCTAAATAAACACATAGATTCA CCTGTAAAACTTTATTTTATATAATAAAGTATTCCACCTTAAATTAAACAATTTATTTTA TTTTAGCAGTTCTGCAAATAGAAAACAGGAAAAAAACTTTTATAAATTAAATATATGTAT GTAAAAATGTGTTATGTGCCATATGTAGCAATTTTTTACAGTATTTCAAAACGAGAAAGA TATCAATGGTGCCTTTATGTTATGTTATGTCGAGAGCAAGTTTTGTACAGTTACAGTGAT TGCTTTTCCACAGTATTTCTGCAAAACCTCTCATAGATTCAGTTTTTGCTGGCTTCTTGT GCATTGCATTATGATGTTGACTGGATGTATGATTTGCAAGACTTGCAACTGTCCCTCTGT TTGCTTGTAGTAGCACCCGATCAGTATGTCTTGTAATGGCACATCCATCCAGATATGCCT CTCTTGTGTATGAAGTTTTCTTTGCTTTCAGAATATGAAATGAGTTGTGTCTACTCTGCC AGCCAAAGGTTTGCCTCATTGGGCTCTGAGATAATAGTAGATCCAACAGCATGCTACTAT TAAATACAGCAAGAAACTGCATTAAGTAATGTTAAATATTAGGAAGAAAGTAATACTGTG ATTTAAAAAAAACTATATTATTAATCAGAAGACAGCTTGCTCTTACTAAAAGGAGCTCTC ATTTACTTTATTTGATTTTATTTTTCTTGACAAAAAGCAACAGTTTTAGGGATAGCTTAG AAAATGGGTTCTGGCTTGCTATCAGGGTAAATCTAACACCTTACAAGAGGACTGAGTGTC ACTTTCTCTCTGGGGGAATGATCCAGCAGCTTATCTAGTTGACAATCAAAACACGGCTGA TAAAGGTGCAATCATTTCTGACATGTATTTTTCACTGATTTTGAAGCTAGTGATTGGTTG TGTCTTCTTGGCTCAAAAAGAAGCATATTACGGCACAAAAAGCCCAGCCCAGACAGCACA TGCAGCATTTTGTCTGAAATACTTCTAGAGTCAAACGTGCCTGCTGTACATAGCGATGAC TTGTCATCATAGGGAAGTATTTCCATCGTAGAGTGTTCAGAAGGAGTGACTGTATAGGTG GAGAGAAGCTTAGTGACTCCGTTGAAATTTTAAAATGTGGATGACCACCCCTTTCTCCCC CTTATTTTTCTTTTATCTTTCCATGTTGCCTTGATCAGGTCATAACTATGCATGAACATT TTTTATCAGGAATGGCCGATGTGTATGTGATTTGTAATCACAAGTAATGATTCATCAGGA AATGTCAATCCTGTTGGAAAGATTGCACCTTTACTTGCAGAAGTGACCCCCACCTGTGTC CTGACCTCTCCATTTACAGGCTCTCTCACCCATTTCCCCCACCTCCTTTAATTTTTGCTT TACTGTCATAAAGTAGGACTAAGATTGGTCTAAGCATTGCATGTTCTTTTGTGATGGTAA ATCCAAAGGAAGGCCTATAAGTATTAACATTTGAAATAACTGCTAATTCAGGAAAATGGA AGAAAAAAAATTATTTGAAACACAGAACCCATTTCATGGCCTGCCTGATATCTGTGAAAT CAGGGCTGGAGCTTTACTTAGGATTCACATGGCCTCCTAGGAACCATGGGACAAATGGGA AACAGGTTATCGGGGGATTCATGAAGTCAGTGAGAGTAATTGCTTCTTTTTTGCGGGTGA ACTGAATGTATTTCTTCACCAAATCTTGATGTTAACAATTAAAAAGAAGAAATGACATGC AAGTAGGTCTTAGCAGAAAAATGCAGGCTGGGCATGAGTCATGTTGTTACCCTCCCACAT GCTCCTACAATCCACAGAGATGCCTGTCTGCAGGTTCTTGAAGTTATTGTTAGTATTTGG TATCTCAAATTTTTCGTCACTGTTCACATGCCACTTTCTCTGTGCACAGTGGTATCCTCA TTTGCTTTTTAACCTACACTGAGGAGTCTTTGTCAGGTTGCACTGATTTTCCAATTCTGC AGTAATGAGTAAGCTCACGGCATGGGGAAGAAGACAGTCAGTCCAATGAAGTTCTCTAAA TTATTTTAACATTGCCTTTGAAGGCCTTGACTCATCCTTAGCTATTTCAATGAAGAAATT CCTACCATGAATTTAAAACCCTAAAAATTCTGTTTCAAATTCTTTGGGCATTGGGGTACT CAGATATCCCATTGTGGAAGAATTTTAAGAATAAATAGAAGTTTCTGTTGAGAACCATGA GCAACATGTTTCTTACAATGAGAATTGCTATGCATTTTAAAATTGCAAATATATATGAAA ATTGAAGACAAGAGGAAATTGTATTTCTAACTTGATTCTGATCACTCACAGAGGTGGCAT ATTATTATAGTTGGGACATCCTTTGCACCCTTCATAAAAAAGGCCAGCTGACTGCTCAGC ATCACCTGCCAAGGCCACTAGATTTGTGTTTACAGGGGTATCTCTGTGATGCTTGTCACA TCACTCTTGACCACCTCTGTTAATAAATTCCGACAGTGCAGTGGCGATCGGAGTGTGAAC TTATGTTCCCAGCATATGGAAAGCTATCTTAGGTTTTAAGGTAGTAGAAATTGCCCAGGA GTTTGACAGCAACTTTGTTTCCCGGGTCTAAAATCGTATCCCACTGAGGTGTATGCAGTG GAGCATAATACATGCAAATACATGCAAAACTCCTTTTGTTTCACCTAAGATTCACTTTCT ATCTTACTTTCCCTTCCTGCCTAGTGTGACTTTTGCCCCCAAGAGTGCCTGGACAGCATT CTAGTTTCTACAAAATGGTCCTCTGTGTAGGTGAATGTGTCCCAAACCTGCTATCACTTT CTTGTTTCAGTGTGACTGTCTTGTTAGAGGTGAAGTTTATCCAGGGTAACTTGCTCACTA ACTATTCCTTTTTATGGCCTGGGGTTAAAGGGCGCATGGCTCACACTGGTGAAAATAAGG AAGGCCTGGTCTTATCTTGTATTAATAATACTGGCTGCATTCCACCAGCCAGAGATTTCT ATCTGCGAAGACCTATGAAACACTGAAGAGAAATGTAGGCAGAAGGAAATGGCCACATAT CACAAGTTCTATTATATATTCTTTTGTAAATACATATTGTATATTACTTGGATGTTTTCT TATATCATTTACTGTCTTTTTGAGTTAATGTCAGTTTTTACTCTCTCAACTTACTATGTA ACATTGTAAATAACATAATGTCCTTTATTATTTATATTTAAGCATCTAACATATAGAGTT GTTTTCATATAAGTTTAAGATAAATGTCAAAAATATATGTTCTTTTGTTTTTCTTTGCTT TAAAATTATGTATCTTTTCCTTTTCTTTTTTTTAAGAATAATTTATTGTTCAGGAGAAAG AATGTATATGTAACTGAAACTATCTGAAGAATGCACATTGAAGGCCGTGAGGTACTGATA AACTAAAGAATTTATTATTCAAAATACTAAGCAATAAGTAATTGTGATTTATTTAAAGTT TTGTCCATTTTCCATGAAAGACATACTGCAATAAAAATGCTACTCTGTGGA |
Protein Sequence | >3084 : length: 700 MEIYSPDMSEVAAERSSSPSTQLSADPSLDGLPAAEDMPEPQTEDGRTPGLVGLAVPCCA CLEAERLRGCLNSEKICIVPILACLVSLCLCIAGLKWVFVDKIFEYDSPTHLDPGGLGQD PIISLDATAASAVWVSSEAYTSPVSRAQSESEVQVTVQGDKAVVSFEPSAAPTPKNRIFA FSFLPSTAPSFPSPTRNPEVRTPKSATQPQTTETNLQTAPKLSTSTSTTGTSHLVKCAEK EKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQ KRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPN PPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHT ESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPH SERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLL VTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKK LANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLE ATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQDPIAV |