| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2776 |
Name | GNAQ |
Synonym | CMC1|G-ALPHA-q|GAQ|SWS;guanine nucleotide binding protein (G protein), q polypeptide;GNAQ;guanine nucleotide binding protein (G protein), q polypeptide |
Definition | guanine nucleotide-binding protein G(q) subunit alpha|guanine nucleotide-binding protein alpha-q |
Position | 9q21 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270 |
Pathway | pertussis toxin-insensitive ccr5 signaling in macrophage;PID BioCarta;100214 |
Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway;PANTHER;P00027 |
Pathway | angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling;PID BioCarta;100236 |
Pathway | thrombin signaling and protease-activated receptors;PID BioCarta;100082 |
Pathway | Metabotropic glutamate receptor group I pathway;PANTHER;P00041 |
Pathway | effects of calcineurin in keratinocyte differentiation;PID BioCarta;100222 |
Pathway | 5HT2 type receptor mediated signaling pathway;PANTHER;P04374 |
Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway;PANTHER;P00042 |
Pathway | Alzheimer's disease;KEGG PATHWAY;hsa05010 |
Pathway | Thyrotropin-releasing hormone receptor signaling pathway;PANTHER;P04394 |
Pathway | Salivary secretion;KEGG PATHWAY;hsa04970 |
Pathway | Huntington's disease;KEGG PATHWAY;hsa05016 |
Pathway | Amoebiasis;KEGG PATHWAY;hsa05146 |
Pathway | Melanogenesis;KEGG PATHWAY;hsa04916 |
Pathway | Cortocotropin releasing factor receptor signaling pathway;PANTHER;P04380 |
Pathway | pkc-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase;PID BioCarta;100100 |
Pathway | Endothelin signaling pathway;PANTHER;P00019 |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | PI3 kinase pathway;PANTHER;P00048 |
Pathway | signaling pathway from g-protein families;PID BioCarta;100153 |
Pathway | Histamine H1 receptor mediated signaling pathway;PANTHER;P04385 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | links between pyk2 and map kinases;PID BioCarta;100057 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | g-protein signaling through tubby proteins;PID BioCarta;100009 |
Pathway | GnRH signaling pathway;KEGG PATHWAY;hsa04912 |
Pathway | actions of nitric oxide in the heart;PID BioCarta;100094 |
Pathway | Chagas disease;KEGG PATHWAY;hsa05142 |
Pathway | cxcr4 signaling pathway;PID BioCarta;100192 |
Pathway | Pancreatic secretion;KEGG PATHWAY;hsa04972 |
Pathway | Gap junction;KEGG PATHWAY;hsa04540 |
Pathway | Oxytocin receptor mediated signaling pathway;PANTHER;P04391 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | ccr3 signaling in eosinophils;PID BioCarta;100215 |
Pathway | Integration of energy metabolism;Reactome;REACT:1505 |
Pathway | Arf6 signaling events;PID Curated;200060 |
Pathway | activation of pkc through g-protein coupled receptors;PID BioCarta;100073 |
Pathway | Long-term depression;KEGG PATHWAY;hsa04730 |
Pathway | Gastric acid secretion;KEGG PATHWAY;hsa04971 |
Disease | Bleeding diathesis due to GNAQ deficiency;OMIM |
External Links | |
Links to Entrez Gene | 2776 |
Links to all GeneRIF Items | 2776 |
Links to iHOP | 2776 |
Sequence Information | |
Nucleotide Sequence | >2776 : length: 6343 AGACTATCCGCTCCCACCGCGCCCCCGGCCCACCTGGTGGCCCCGGCCCTGGCCGCCGCC CCCGCGGCGGTTCCCGGAGCTCGTCCCGGACGCGCGCCCGGGCGGCGGGGGCTCGGCGGC CACCGCTGCCTCGGGGGAGCGAGGGCGGGAGGGTGTGTGTGCGCGCTGTGAGCAGGGGGT GCCGGCGGGGCTGCAGCGGAGGCACTTTGGAAGAATGACTCTGGAGTCCATCATGGCGTG CTGCCTGAGCGAGGAGGCCAAGGAAGCCCGGCGGATCAACGACGAGATCGAGCGGCAGCT CCGCAGGGACAAGCGGGACGCCCGCCGGGAGCTCAAGCTGCTGCTGCTCGGGACAGGAGA GAGTGGCAAGAGTACGTTTATCAAGCAGATGAGAATCATCCATGGGTCAGGATACTCTGA TGAAGATAAAAGGGGCTTCACCAAGCTGGTGTATCAGAACATCTTCACGGCCATGCAGGC CATGATCAGAGCCATGGACACACTCAAGATCCCATACAAGTATGAGCACAATAAGGCTCA TGCACAATTAGTTCGAGAAGTTGATGTGGAGAAGGTGTCTGCTTTTGAGAATCCATATGT AGATGCAATAAAGAGTTTATGGAATGATCCTGGAATCCAGGAATGCTATGATAGACGACG AGAATATCAATTATCTGACTCTACCAAATACTATCTTAATGACTTGGACCGCGTAGCTGA CCCTGCCTACCTGCCTACGCAACAAGATGTGCTTAGAGTTCGAGTCCCCACCACAGGGAT CATCGAATACCCCTTTGACTTACAAAGTGTCATTTTCAGAATGGTCGATGTAGGGGGCCA AAGGTCAGAGAGAAGAAAATGGATACACTGCTTTGAAAATGTCACCTCTATCATGTTTCT AGTAGCGCTTAGTGAATATGATCAAGTTCTCGTGGAGTCAGACAATGAGAACCGAATGGA GGAAAGCAAGGCTCTCTTTAGAACAATTATCACATACCCCTGGTTCCAGAACTCCTCGGT TATTCTGTTCTTAAACAAGAAAGATCTTCTAGAGGAGAAAATCATGTATTCCCATCTAGT CGACTACTTCCCAGAATATGATGGACCCCAGAGAGATGCCCAGGCAGCCCGAGAATTCAT TCTGAAGATGTTCGTGGACCTGAACCCAGACAGTGACAAAATTATCTACTCCCACTTCAC GTGCGCCACAGACACCGAGAATATCCGCTTTGTCTTTGCTGCCGTCAAGGACACCATCCT CCAGTTGAACCTGAAGGAGTACAATCTGGTCTAATTGTGCCTCCTAGACACCCGCCCTGC CCTTCCCTGGTGGGCTATTGAAGATACACAAGAGGGACTGTATTTCTGTGGAAAACAATT TGCATAATACTAATTTATTGCCGTCCTGGACTCTGTGTGAGCGTGTCCACAGAGTTTGTA GTAAATATTATGATTTTATTTAAACTATTCAGAGGAAAAACAGAGGATGCTGAAGTACAG TCCCAGCACATTTCCTCTCTATCTTTTTTTTAGGCAAAACCTTGTGACTCAGTGTATTTT AAATTCTCAGTCATGCACTCACAAAGATAAGACTTGTTTCTTTCTGTCTCTCTCTCTTTT TCTTTTCTATGGAGCAAAACAAAGCTGATTTCCCTTTTTTCTTCCCCCGCTAATTCATAC CTCCCTCCTGATGTTTTTCCCAGGTTACAATGGCCTTTATCCTAGTTCCATTCTTGGTCA AGTTTTTCTCTCAAATGATACAGTCAGGACACATCGTTCGATTTAAGCCATCATCAGCTT AATTTAAGTTTGTAGTTTTTGCTGAAGGATTATATGTATTAATACTTACGGTTTTAAATG TGTTGCTTTGGATACACACATAGTTTCTTTTTTAATAGAATATACTGTCTTGTCTCACTT TGGACTGGGACAGTGGATGCCCATCTAAAAGTTAAGTGTCATTTCTTTTAGATGTTTACC TTCAGCCATAGCTTGATTGCTCAGAGAAATATGCAGAAGGCAGGATCAAAGACACACAGG AGTCCTTTCTTTTGAAATGCCACGTGCCATTGTCTTTCCTCCCTTCTTTGCTTCTTTTTC TTACCCTCTCTTTCAATTGCAGATGCCAAAAAAGATGCCAACAGACACTACATTACCCTA ATGGCTGCTACCCAGAACCTTTTTATAGGTTGTTCTTAATTTTTTTGTTGTTGTTGTTCA AGCTTTTCCTTTCTTTTTTTTCTTGGTGTTTGGGCCACGATTTTAAAATGACTTTTATTA TGGGTATGTGTTGCCAAAGCTGGCTTTTTGTCAAATAAAATGAATACGAACTTAAAAAAT AAAAGCTGGTATCTTAAAATGTAAGAGAGTAAGACTGTGAAGCCTAAAATGACTGGCTGA GAATGAACCAGAAATGCCATTTGCCAAACAGTTGTAACTAGAAATTTGATTCTCACGGTC CATTCTTTTCTTTGTCCTTAAGATGACATTGTTAGTGTTCACGTCCCATGTTCAGTGTCC AAACCGGCAATGTAAAAAGTATCCTGTGTGGTTTAACAGGAAATCTGTTTATGTCTCTTT ATTTGAAACCAGTTTTACTCTCAGTGGTTCTTTAAGTTCAATGAAGTCTGCCAGGAACAT TGGTTGGTAGTATTATTCCGACACCTTTAATTTCCAAAATCTGAAGTTCCTGCTAGTTTA CCACCTTCATGATCTTCTTGAACTGGTAACTGATTAGGTTGAACTTATGGAAGATTTGTG GACTTAACTCAAAAGTAACCTCTCAGTGTTCTATAGAACATGTATTTGTGTAACTGAACC TACCAGGAGAAATGTTTGGAATTCTATATGTGCAATTTTTCAACAAATGCAAAAAAAATA CAGCACATGTATTGACAAGCTTCTGTCAAGCAGCTTGAGTTGAAATTTGATTTAAGAAAA TAAATCATGATTGTTCAAAGCTGCTGGGACGTTAGAATTAGGCCATGATACTGGTCTCAT TTTAACTACAGTGGTATTTGGCACTAGTGTAAACTTCCATATAAATCACTCTTTTGGAAC AACAAAGGGGGAGGGAGAAAAATCACGGCCTGTTAAATGAGTACCAAAGCCGCCCAACAG TAATGAGATGTTCTCATCCTTGATTCTCCCAGCCTCAAACAACACAGCTTACTTTTTTTT TCCCTTGCTCAGAAAGTACCTGTAATTTAACAAACAGACTGCCTGTAGGTATAGTGCAAT TACAAATGCTCTAATCATTGTACATACATCTCTCTTGATATTGCAGCATCCATACTGGCT TTGTAATCATTAATTTTTTGGCAGATTGAATGTGCTGTATTGATATGTATCTATGTAATT GTATTGTATGTCTATAGCTAATTCACGTTTTGAATAATGTTATTTTATTTACTTTTTTAA GAGAGGAGAATGTAAATTTGTCAGTTTATTTCTGACTAGGGATATTTTCTTTCCATTTAG AAAAGAAGAAAAAAAAAAAACCTTACTGTCATACAGAGCGGTACTAGCGTCGTGCTGTAT AAAATCATTTGCACATTCCTGAGTAGAGGTATACTGATTATAAGACCCAAAGGTAATTTC ATAGCAAAATACATAAAATCAGTCGGAGCTTTTATACAAACATGGAAACCAACTTTGTAG AACTTTTGCCATTTGATCTAGGATTGGAATATGAGCTTTTATACAATTCATATTCTTATT TGGCAAATGCACAGTTTAGTATTACCTCTCTGATGGCCTTTACTAGAAAGGCAGTTTTAG AAGCTATTGTGATCCACTAAGGAAATGTTTTAACAGCTAGAGACCACTGCTTGCCTGAAA GGGCGTTCTTAAATTTGGTGCAGCAAAAAAAAAAAAAAAAAAAAAAAAAATTAAACAACA ACATTTGAAGGCCTACAGTGTGTATAGAGAAAACCTCATCACAAGATCATAAGTGTTACA GTTTTAGGGAATCAAGATATTCTATTTAATAGAGCTATAGTAAATGTAGTCAATTAAACC TGATCTCAAAGCTTGAAGAAGCTGAGCAAAACAGGGAAAGATTGTTATATTTGTCTTTAT GAAATTGGGATGGAATTTGCTATGCAGAATTGAGGTTTGTGGCTTCGCTGTTCCTGTAGG GTGCATGACAAGATCCCTTCTCTTGAGAAAGGAAAAAATTGATCACCCTAGCAGCAGTGA TGCATAGAAACCTAATTTTAGCCACACCAGTCAATCGAAGCTAAAGGATTTTCTTTTTTG TTTCTTCGGGGTTTTATTGAAGGGGCTAGGGGCGGGACGGGATTCTTTTCAGTTTTGTAT AAAAACAAAGTTTACTCATGCTTTATATTATATTGTGATTGCAAGCGTTATAAGCGTGTG CCACTGGCCTCCTATTGTTGATGCTTAGGTAATGGAGGCCTGTGGTGAGTTTTATGGTGA CTTGGGCATGTCTTATTCAAAAACAAAAACATAAAACACAGAAACCTTTCTTCAGCATAC CAAGGCAAGCAGCCATTTCATGACTCACTTAACACATTGCAGTGTACCAGTTTACAGATG ATTTTTCCCTTTTTGCGTGACATGGCAGTTCTAACCCCCAGAGAATTCCTTATTTGTAAA TTGGAAGTTTCTACTATGCCTTACAGAGCTTAAATTCAGAAGTTTGTGCCTCATATCTGA AACAAAGGGAAATAACACACCCATTCAAAAGTAAATAAATCTCCTAGAAGTTTTTGTTTT TAACATTTCCATATAAAGAGCTCTGTTGAATGTCATGAATAGACTGGAAAAAAAAATTTT AAGAACCTGCATATGTTGTTTACTAGCAGATGACAACTACAAAAGGAATCTGAAGAACAC GTAAAACTTGTATTTTTTTTTTTTTGGTAGATTAACTAGCAGGCCTATTTTAAAAAGGTA ATTCAGCTAAAGGGCAATTTACTTTTTTGTACTTCAGACTATCTTGATTGTCAAAGTGTA CGAACTGTAATTTTAAAATTTATACTGCCACATGATTGTAAATTTTAGTTGTCTTAAGTT AGGAATTGGTGAAAAGCTATTTATGCTGGATTTGGGTCAAAATGACTTATTTGCAAAAAA ATAAATAATGGGAAGAAAGGGCTGTATAATGAAATACTGCAAGACTCACATATTGGTTGG AAATTTCCCTCAAATCACCTACCGATTACCCTTGATTTCCCTTTGTTTTCAGTTTCTCAA AACGAATGAAATGAAATATAGCAGAATGTTAACCCATATAAAAATAAAGTGTACCCAAAT ATTGTAATGTATATTGCTGCTCTTCTTCAAATTAAATAAGGGTTTAAAACCACTTAATTG GTAATCAACATCTCAATTGATACAAATAAGGTGTGCTTGGTATACATTAATATTTTCTTC CAAAGATATATCTTTGGTTAGAAACACAAAAAAATAAAACTAGTAATATTGTATGTTTAT CTATCTCTACATATTTCCAGCATATGTAGCGTTAATAGATCTGTCCTGGTAACTGTGTCT TTGGGATTTCATTTTGGTTCCATCAAATTAGGAAAAGAAATGGCTTAGTTGTATATGATT AGCTAGAGATTTTTGGAGCCAGACACCTGCTGTTTAGTAGATAACTTAGTACAGACCCTA AACTTGTCATTTGTTTTTCTCACAGAATAGCCATTTCCTGCTGTCTTCCCAATGATCACT GCCCTTTCAATAACACTCTTGCCTCTAGAATCATATGTTCAAAGTATGAATACACACCTA GCACATAGTAGGTGCTCAAATATTAATTTCCTCCTTGCCTTCCTTATCTACCCTGTGTCC TCCATTTCCCCGTATGATTCCAACCCAATATAGCAAATGACATTTACATGTTATGAAAAC ATCTATTGGGTAAAATCAGATCTTGGATAAAGAAATTCTGACTTTTATATAAGCTTTTGG TAGACAGAAAAAACAGAAAGGTATTCGTTGGTAGAACATTTTTAAGTTCAGGAAAGAAAG CTGGAATAATACTACGTAACTTTGTCCAGGTTACTTTGACTGAAACACGTTTTTGGTGGA TTTCTTTTCCTCAAAGAACTCTCTAAATGCAACTCCTTGCTGGATTCCTCACCCATCATC CTGTTGGAAACCCTTACTAGACCTATGTATTTAGGGAGTTTTGTCAGAAAACATTTTTAA CTTGCAGTATTTAAAAGAATATTTACTGTTCCTAAAATGTCATTCAAATGCATGTACTGT CTATTGTTTGGGGATGGGAACTAGTTTTGCAAAAAACACCTAATGTTGTATAATAATGCC CCAATGATCTTGCTGGTTAAAAATACAGTATTTTTGGCCATAA |
Protein Sequence | >2776 : length: 359 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK VSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVL RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV |