| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2768 |
Name | GNA12 |
Synonym | NNX3|RMP|gep;guanine nucleotide binding protein (G protein) alpha 12;GNA12;guanine nucleotide binding protein (G protein) alpha 12 |
Definition | G-protein subunit alpha-12|WUGSC:H_GS165O14.2|g alpha-12|guanine nucleotide-binding protein subunit alpha-12 |
Position | 7p22.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270 |
Pathway | LPA receptor mediated events;PID Curated;200011 |
Pathway | S1P3 pathway;PID Curated;200035 |
Pathway | S1P5 pathway;PID Curated;200063 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Endothelins;PID Curated;200004 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | rho-selective guanine exchange factor akap13 mediates stress fiber formation;PID BioCarta;100248 |
Pathway | pkc-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase;PID BioCarta;100100 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | S1P2 pathway;PID Curated;200181 |
Pathway | Long-term depression;KEGG PATHWAY;hsa04730 |
Pathway | S1P4 pathway;PID Curated;200043 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Sphingosine 1-phosphate (S1P) pathway;PID Curated;200104 |
Disease | Height;NHGRI |
Disease | Prostate cancer;FunDO |
Disease | Azoospermia;FunDO |
Disease | height;GAD |
Disease | Leukemia;FunDO |
Disease | Hyperaldosteronism;FunDO |
Disease | Breast cancer;FunDO |
Disease | DEVELOPMENTAL;GAD |
Disease | Congenital abnormality;FunDO |
Disease | Neoplasm metastasis;FunDO |
External Links | |
Links to Entrez Gene | 2768 |
Links to all GeneRIF Items | 2768 |
Links to iHOP | 2768 |
Sequence Information | |
Nucleotide Sequence | >2768 : length: 4398 GGGCGACGAGTGCGGGCCTCGGAGCGACTGCAGCGGCGGCGGCGGACGCGGCCTGAGGCG AGCGGCGGGGCGTGGGGCGGTGCCTCGGCCCGGGCTCGCCCTCGCCGGCGGGAGCGTCCA TGGCCCCCGGGCGCCGGCGGGGCGCGGCCGCGGCCTGAGGGGCCATGTCCGGGGTGGTGC GGACCCTCAGCCGCTGCCTGCTGCCGGCCGAGGCCGGCGGGGCCCGCGAGCGCAGGGCGG GCAGCGGCGCGCGCGACGCGGAGCGCGAGGCCCGGAGGCGTAGCCGCGACATCGACGCGC TGCTGGCCCGCGAGCGGCGCGCGGTCCGGCGCCTGGTGAAGATCCTGCTGCTGGGCGCGG GCGAGAGCGGCAAGTCCACGTTCCTCAAGCAGATGCGCATCATCCACGGCCGCGAGTTCG ACCAGAAGGCGCTGCTGGAGTTCCGCGACACCATCTTCGACAACATCCTCAAGGGCTCAA GGGTTCTTGTTGATGCACGAGATAAGCTTGGCATTCCTTGGCAGTATTCTGAAAATGAGA AGCATGGGATGTTCCTGATGGCCTTCGAGAACAAGGCGGGGCTGCCTGTGGAGCCGGCCA CCTTCCAGCTGTACGTCCCGGCCCTGAGCGCACTCTGGAGGGATTCTGGCATCAGGGAGG CTTTCAGCCGGAGAAGCGAGTTTCAGCTGGGGGAGTCGGTGAAGTACTTCCTGGACAACT TGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTGCTGGCTAGGA AAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGG TGGATGTGGGCGGCCAGCGGTCCCAGCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCA CGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATGGAGGACAGGC GCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCT TCTTCAACGTCTCCATCATTCTCTTCCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGA AGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCACAGGCTGGAGG ACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCAC TCTTCCACCACTTCACCACCGCCATCGACACCGAGAACGTCCGCTTCGTGTTCCATGCTG TGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGAGCGAGGAAGC CCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGTGTGTG TTGTCTGTGTGGTCCTTGAGTGGGTTTCTCGGATCCGTGCCCTGGAATACCTGGCTCAGG AATGCTGTCAGACCAGCCAGCCAGCGAGCTCTAGGCAAAAGGACATGGAAACTGTCACGT TAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTTGTGAA TACGGAACACCTAATCACACAGCTTGCTTTGCTTTTACAGAAACGTTCCTCTTTTTCTGA CGCAGTTTAATTGAGGACCGTGTTGTGTGTGTATGTGTGTACACACGCTCTGTCTTTAAT GACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTCTTCCC TGAGACAGACTAACCTGAAAGCTTTGCCTAACAGTAGCTTGTAGAGATCCAGTGCACGCC GATGCTGCTAAACTCAGTGCCTGAGCCCGGCCCTGCAGCCCCAGCCGCAGTGTCTGAAGG CCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAGAGCCC CTAGTCCAAGCCTCTCAGATGAAGCTGAGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTG AGGACGGGCTGCAGAGCTCTGCAGGTGTGGATTCACCTTACGCCCCTACAGCAGGCTCAG CCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCCCACGG TGACTGCCGCTCCGTCCGTGCACACACAGCGGTGCTCTTCTCCCCTTAGCCACCCACTGC CCAACCCAACGGCAAAGACACAGAAACCAGGTCCCCTTGCAGACGGCTCTCCCATCTTCC TGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGAAACAT TCCTCTTCTGGGGCTTCAGAAAGCTGGCAAGGCCACTAGCAGAGCTTTTGTTAATGCCCC AGCTGCTTGGCGAGCTAACAGCTGACCTTTCGGGAAGCCCACAGACGCTGGAGGAATCTT GAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGCCGCTC TCCCTAAGTCTGATTCTCATCGAGGCCCCTCGCTTCTATGACTGTGCTTGCAGAAGAGTA AACACTCTCGGATGCCGCTGTCCTGGGGGAGCCCGCGGGAGCCTGTGAATGTTGATACGA GCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCACTGTG TTTAAAATACATTGCATTCCAAGCTGGTCCCCTCTGTGTATCACTCTACTGAGAAATCCT GCCTAGTGTGTTTTGGGATGTGTCCTAGCATTTACAAGAAAATGAAAAGCGTCCTCTTAA TTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGAGGCCG TGCTGCCCCGAGCCCCGAGCCCCTCTGCAGCTCACCCTTGGCTTGTTTTCCGCAAACCCG GTAAACGCAAGCCCTTGGGGCAGATGCAGAAGCAGAAGAGGGAGGGGAAACCTGCCTCTG GGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCGCAGTG CTCGAGGCTGTGTGTCAGTGTTTGCTGGGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAA GTCGCTGTTTTTGTACTGCTTCTGTGGCTCTTCACAGACCTCACGGATGTGACCGGAGAT GAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGGGGTGG TCTCAGGTCCCATTTGCAGTCTGCAACAGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAG CTTTGTTTGCCTTCTGGGTCAGCTTTCGCTGTGTCTCCTGTGTGTGTTAGAATCCAGAGC CCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCTGTTGG CGACAGCAGCGCTGTGATTCGCGTAGCAGGGGAGTTGTTTGAAACACCTTCCTGAGTAGT CCGGCCTTGTCAATGAGTGCTTGTTTTCCTTTAAACAGTCTGACATATTTACTCGTCACT TTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATAGAAAG CGCAGGGGGATGGCCCCCGGCGCGGGCTCTTGACCCGCTCAGCGCTGACCCCACCGCCCT GGCCGAGGCACTTGGCCTTGCTGAGCTGGACTTCCTCCTCCTCCTCCTCATGACCGGGGT GAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATTGGAGA AGAAGGAAACTCTGCAAGGCTAAACTGTCATTCACAACTTGGCTACACATAGACTCTAGT CAGTTTTGTCTCCAGAACCTTAGGCTTTTGTATTTTTTAATTTTAATTTCACTGTTAATC CTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAATTATTG CAAAAATGTAACAATAAAGTTCCTCAAAATAAGATCTGTTCCTCATAGCTATACTGTGTA CACATAAGACGCATATAGGGTTTTACTGAAATCTATTTTTAACTCTTATGTTCGTAGAGA AATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAATTCTTA TTGTAATTTTCCTACTTCTTTGATAAAAGAAAAATAAGTCAGATTGTTAACTCCAAGATT GAAAAAAAAAACTCTTGAAAGAAGATTATTAGTTGTAACTAATTTAGGGGTTCTGGGCAC AGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCCGGGTC AGTTGTTCATGGTGTAAGCTTTGCACAGTGTATTAACATTGGGAGGGTCTGGCTTGAAAA TTTGGCCACCCTCAGCCTCTGAATGTTTATTAAAATAAATTTAGTCTTTCTTTGCTTAAT ATAAAAAAAAAAAAAAAA |
Protein Sequence | >2768 : length: 381 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR FVFHAVKDTILQENLKDIMLQ |