| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2737 |
Name | GLI3 |
Synonym | ACLS|GCPS|GLI3-190|GLI3FL|PAP-A|PAPA|PAPA1|PAPB|PHS|PPDIV;GLI family zinc finger 3;GLI3;GLI family zinc finger 3 |
Definition | GLI-Kruppel family member GLI3|glioma-associated oncogene family zinc finger 3|oncogene GLI3|transcriptional activator GLI3|zinc finger protein GLI3 |
Position | 7p13 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Hedgehog signaling pathway;PANTHER;P00025 |
Pathway | Hedgehog signaling events mediated by Gli proteins;PID Curated;200147 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Basal cell carcinoma;KEGG PATHWAY;hsa05217 |
Pathway | Hedgehog signaling pathway;KEGG PATHWAY;hsa04340 |
Disease | Acrocallosal syndrome;OMIM |
Disease | Polydactyly, preaxial, type IV;OMIM |
Disease | talipes equinovarus;GAD |
Disease | Congenital abnormality;FunDO |
Disease | Greig cephalopolysyndactyly syndrome;OMIM |
Disease | Hypothalamic hamartomas, somatic;OMIM |
Disease | Pallister-Hall syndrome;OMIM |
Disease | DEVELOPMENTAL;GAD |
Disease | Polydactyly, postaxial, types A1 and B;OMIM |
Disease | Intractable epilepsy;FunDO |
External Links | |
Links to Entrez Gene | 2737 |
Links to all GeneRIF Items | 2737 |
Links to iHOP | 2737 |
Sequence Information | |
Nucleotide Sequence | >2737 : length: 8442 GCAGCACTCCAAGTTTTCCCAACTTCGCCCCCTGCGGCGGCAGGCGTCCTGCTGCTCAGC GCGTCCCCTCCGAGCCCGAGAGTGGCTGAAAGAAAAGGGACTGGGCGGGGGCCGGGGCGG AGGAAGAGAGAGTGCGAGGGAGCGAGGAGAGTCCGGCAACATCTGTTAAAACTTGGGGGA GGAGGAGCGCGGGGAGGAGGAGGAAGAGGAGGAGAGAAGGGAAGGAGGGAGCGCGCGGGA GGGGAGCGCGGAGCCGAGGGACAACTTTTCCACCCCGGCATTTTTGGTCGAAGAGAGCTG AAGTAATGAGAAGACATCATGGAGGCCCAGTCCCACAGCTCCACGACCACTGAAAAGAAA AAAGTTGAGAATTCCATAGTGAAGTGCTCCACTCGAACAGATGTGAGCGAGAAAGCCGTT GCCTCCAGCACCACTTCTAATGAGGATGAAAGTCCTGGACAGACTTATCACAGAGAGAGA AGAAACGCAATCACTATGCAGCCACAGAATGTCCAGGGGCTCAGCAAAGTCAGTGAGGAA CCTTCAACATCGAGTGACGAGAGGGCCTCATTGATCAAGAAAGAGATCCATGGGTCCCTG CCACACGTGGCGGAGCCCTCTGTGCCGTACCGCGGGACGGTGTTTGCCATGGACCCCAGG AATGGTTACATGGAGCCCCACTACCACCCTCCTCATCTTTTCCCTGCCTTCCATCCTCCT GTACCAATTGATGCCAGACATCATGAGGGCCGTTACCATTACGATCCATCTCCGATTCCT CCATTGCATATGACTTCCGCCTTATCTAGTAGCCCTACGTATCCGGACCTGCCCTTCATT AGGATCTCCCCACACCGGAACCCCACTGCTGCTTCCGAGTCTCCCTTCAGCCCTCCACAT CCCTACATTAATCCCTACATGGACTATATCCGCTCCTTGCACAGCAGCCCATCGCTCTCC ATGATCTCAGCAACCCGTGGGCTGAGCCCTACAGATGCGCCCCATGCAGGAGTCAGCCCA GCAGAATACTATCATCAGATGGCCCTGCTAACTGGCCAGCGCAGCCCCTATGCAGACATT ATTCCCTCAGCTGCCACCGCCGGCACGGGGGCCATCCACATGGAATATCTTCATGCTATG GATAGCACCAGATTCTCCAGCCCCAGGCTGTCAGCCAGGCCGAGCCGAAAACGTACACTG TCCATATCACCACTCTCCGATCATAGCTTTGACCTTCAGACCATGATAAGGACGTCTCCC AACTCCTTGGTCACGATTCTCAATAATTCCCGTAGCAGCTCTTCAGCAAGTGGCTCCTAT GGTCACTTATCTGCAAGTGCAATCAGCCCTGCCTTGAGCTTCACCTACTCTTCCGCGCCC GTCTCTCTCCACATGCATCAGCAGATCCTAAGCCGACAACAGAGCTTAGGTTCAGCCTTT GGACACAGCCCTCCACTCATCCACCCTGCCCCAACTTTTCCAACACAGAGGCCTATTCCA GGGATCCCTACGGTTCTGAACCCCGTCCAGGTCAGCTCCGGCCCTTCTGAGTCCTCACAG AACAAGCCCACGAGTGAGTCTGCAGTGAGCAGCACTGGTGACCCGATGCACAACAAGAGG TCCAAGATCAAACCCGATGAAGACCTCCCCAGCCCAGGGGCTCGGGGGCAGCAGGAACAG CCCGAAGGAACAACCCTTGTCAAGGAGGAAGGGGACAAAGATGAAAGCAAACAGGAGCCT GAAGTCATCTATGAGACAAACTGCCACTGGGAAGGCTGCGCGAGGGAGTTCGACACCCAA GAGCAGCTTGTGCACCATATAAATAACGACCATATTCATGGAGAGAAGAAGGAGTTCGTG TGCAGGTGGCTGGACTGCTCAAGAGAGCAGAAACCCTTCAAAGCCCAGTATATGTTGGTA GTGCATATGAGAAGACACACGGGCGAGAAGCCTCACAAATGCACTTTTGAAGGTTGCACA AAGGCCTACTCGAGACTAGAAAACTTGAAAACACACTTGAGATCTCACACTGGAGAGAAA CCATACGTCTGTGAGCACGAAGGTTGCAACAAGGCTTTCTCAAATGCCTCTGATCGCGCC AAACACCAAAACAGAACGCATTCCAATGAGAAACCATATGTGTGCAAAATCCCAGGCTGC ACTAAGCGTTACACAGACCCAAGCTCCCTCCGGAAACATGTGAAGACAGTGCATGGCCCA GAGGCTCATGTCACCAAGAAGCAGCGAGGGGACATCCATCCTCGGCCGCCACCCCCGAGA GATTCCGGCAGCCATTCACAGTCCAGGTCGCCTGGCCGACCGACTCAGGGAGCCCTTGGT GAGCAGCAGGACCTCAGCAACACTACCTCAAAGCGGGAAGAATGCCTCCAGGTGAAAACC GTCAAGGCAGAGAAGCCAATGACATCTCAGCCAAGCCCTGGTGGTCAGTCTTCATGCAGC AGCCAACAGTCCCCCATCAGCAACTATTCCAACAGTGGGCTCGAGCTTCCTCTGACCGAT GGAGGTAGTATAGGAGACCTCAGTGCCATCGATGAAACCCCAATCATGGACTCAACCATT TCCACTGCAACCACAGCCCTTGCTTTGCAAGCCAGGAGAAACCCGGCAGGGACCAAATGG ATGGAGCACGTAAAACTAGAAAGGCTAAAACAAGTGAATGGAATGTTTCCGCGACTGAAC CCCATTCTACCCCCTAAAGCCCCTGCGGTCTCTCCTCTCATAGGAAATGGCACACAGTCC AACAACACCTGCAGCTTGGGTGGGCCCATGACGCTTCTCCCGGGCAGAAGCGACCTCTCT GGGGTGGACGTCACTATGCTGAACATGCTCAACAGAAGGGACAGCAGCGCCAGCACCATC AGCTCGGCCTACCTGAGCAGCCGCCGCTCCTCAGGGATCTCGCCCTGCTTCTCCAGCCGC CGCTCCAGCGAGGCGTCACAGGCCGAGGGCCGGCCGCAGAACGTGAGCGTGGCCGACTCC TACGACCCCATCTCCACCGACGCCTCGCGCCGCTCCAGCGAAGCCAGCCAGAGCGACGGC CTGCCCAGCCTGCTCAGCCTCACGCCCGCCCAGCAGTACCGCCTCAAGGCCAAGTACGCG GCTGCCACAGGAGGGCCGCCGCCGACGCCCCTGCCCAACATGGAGAGGATGAGCCTGAAG ACGCGCCTGGCGCTGCTCGGGGATGCCCTCGAGCCTGGCGTGGCCCTGCCTCCAGTTCAT GCCCCGAGGAGGTGCAGCGACGGGGGAGCCCACGGCTACGGGCGGCGCCACCTGCAGCCG CACGATGCGCCGGGCCACGGCGTGAGGAGGGCCAGCGACCCGGTGCGGACAGGCTCCGAG GGCCTGGCCCTGCCTCGTGTGCCGCGCTTCAGCAGCCTCAGCAGCTGCAACCCCCCGGCG ATGGCCACGTCCGCGGAGAAGCGCAGTCTCGTGCTTCAGAATTACACGCGGCCCGAGGGC GGCCAGTCCCGAAACTTCCACTCGTCCCCCTGTCCTCCCAGCATCACCGAGAACGTCACC CTGGAGTCCCTGACCATGGACGCTGATGCCAACCTGAACGATGAGGATTTCCTGCCGGAC GACGTGGTGCAGTATTTAAATTCCCAGAACCAAGCAGGGTACGAGCAGCACTTCCCCAGC GCCCTCCCGGACGACAGCAAAGTGCCCCACGGGCCCGGTGACTTTGACGCGCCCGGGCTG CCAGACAGCCACGCTGGCCAGCAGTTCCATGCCCTCGAGCAGCCCTGCCCCGAGGGCAGC AAAACCGACCTGCCCATTCAGTGGAACGAAGTCAGCTCCGGAAGCGCCGACCTGTCCTCC TCCAAGCTCAAGTGTGGGCCGCGGCCCGCTGTGCCGCAGACTCGCGCCTTTGGGTTCTGC AACGGCATGGTCGTCCACCCGCAGAACCCCTTGAGGAGCGGGCCTGCTGGGGGCTATCAG ACCCTCGGGGAGAACAGCAACCCCTACGGTGGCCCAGAGCACTTGATGCTCCACAACAGC CCCGGAAGTGGCACCAGTGGAAACGCCTTCCATGAACAGCCCTGTAAGGCCCCGCAGTAT GGGAACTGTCTCAACAGGCAGCCAGTGGCCCCTGGTGCACTCGACGGTGCCTGTGGTGCC GGGATTCAAGCCTCAAAGCTGAAGAGCACCCCCATGCAAGGGAGCGGGGGCCAGCTGAAT TTCGGCCTGCCGGTAGCGCCAAATGAGTCAGCTGGCAGCATGGTGAATGGCATGCAGAAC CAGGACCCAGTGGGACAGGGGTACCTGGCTCACCAGCTCCTCGGCGACAGCATGCAGCAC CCGGGGGCAGGCCGCCCCGGTCAGCAGATGCTTGGGCAGATTAGTGCTACCTCACACATC AACATCTACCAAGGGCCAGAGAGCTGCCTGCCAGGGGCTCACGGCATGGGCAGCCAGCCG TCAAGCTTGGCAGTTGTCAGGGGCTACCAGCCATGTGCCAGCTTTGGGGGCAGCAGGCGC CAGGCTATGCCGAGGGACAGCCTTGCTCTGCAGTCAGGACAGCTCAGTGACACAAGTCAG ACCTGCAGGGTGAATGGTATCAAGATGGAGATGAAAGGGCAGCCCCATCCGCTGTGCTCT AATCTGCAGAATTACTCTGGTCAGTTCTATGACCAAACCGTGGGCTTCAGTCAGCAAGAC ACGAAAGCTGGTTCATTCTCTATTTCAGACGCCAGCTGCCTGCTACAGGGGACCAGCGCC AAAAACTCTGAGTTACTTTCCCCAGGTGCTAATCAGGTGACAAGCACAGTGGACAGCCTC GACAGCCATGACCTGGAAGGGGTACAGATTGACTTCGATGCCATCATAGACGATGGGGAC CACTCCAGCCTGATGTCGGGGGCCCTGAGCCCAAGTATCATTCAGAACCTTTCCCATAGC TCCTCCCGCCTCACCACGCCTCGGGCGTCCCTCCCATTCCCAGCGCTGTCCATGAGCACC ACCAACATGGCTATCGGGGACATGAGTTCTTTGCTGACCTCCCTAGCGGAAGAAAGCAAA TTCCTTGCAGTTATGCAATAGGCTTTAGGAAAAAAAGACTGCAACCAACGGAAATCAATA GGAGTTGAAGAGATTAAACTGACTTTGTTTTGGCTGTTTTTTTAGTTCTGTATGTATTTT AGCAATCTCATCTCACCTAACTGAGATGTGTTTCAATTATATTCCTTTTATGGAAAAGGA CTCTGAAAAACCCTAAAGTATTCTAGGGAGAAACTGTCTTCCATTTCAGTTTTGAATCAG TATTGTTACACTCAAACCACCCTCTTTTTAAAAAAAAAAAAAAAAACTGTAAGCCCCGCC CCCTTTTTAGTAAACCGATGTAAATTTGTGATGTGCATATTCTTCTTTCTTTTAGAAGAG CAGTCAAATTAAAGGATTTGACATGTTTTGCTGTTGCTCAAAGGAAATAGGAGTTGGTGT GCTTGTGACCAAGGGGTTACACTTCCAGCTTTTAAAATTCTCCTTTACATGTGCTCAGTG TTTTGTTTTGTGTTTTGGTTTCTGTTTTTTATTTTAATTCCCACATTGGGCACAAGAATC AGAATATGGATAGCTAGTTTAAGAAACTTTTGTGGGTGCACTGTAGCATAGATGACAGAA TATTGATGTTCCCCCCATCTCCAATTCAGTTCAGGGCATTCCACAGTTAAACAGAAATGG GAACGTGGGGCTCTTATAAATGAAATGGGCGCTCACAGTTTTGGTTTTCAGCTCTTCATG TCTGTAAGTGTGCTTTGGGGGAGGCTATGTCTGTATGGTCGATTCTCAGTTATCACATTT GCCTCTCCTCCCACTACCTTCATGAACATTCAGTGCTGTTTCGCACTGCAGTTAGAGAGA AGGGACGGACAGTTGGTGACACTCAGCCACATTGCTACTTTTATCTGTTCTGGTAAGAAG TTAGATAGATGGTAGATTGAAGCAATTGGGTAGAATTAGTTGGGGGAATATTTATGAGTT GCTGTGTTTGTTGATTAGTTCCATCTCTTTCCCATTTTAACTGAGAATTGATTATATATA GCTCTAAGTATATAGGTATTTAAACAACCCCACAAGCGGCTGTATCAGTAACATTTATTA ATTCCACTATAGTGAGGGAGGATTTCCATTCTAAATACCTTATTTTGAGGGATTTATAAA ACTTAGTTGTAAAAGAGAAAGCCCACATAGTGGGAATAAATTGCTTCAGCCATTTTTAGT ATTTGAGAGCACTAGGGAAGATGTTTAGTAGCTGTGTGGATGCCTTTTTTCACACCCTGT CTATTGAATGCTGCATCCATTCACGAAGTTAAATGTTACATGCAGTTAGTCCTTAATGTG GACTGGATCTGTACTTTTGTTTTGGATTAAAACATTTAAAGATTTTTGAAGTGCAGCTAC TCCCCACGTGCATTTGATACACATAAAAGTCATACTGTGTGTGCACAAAGAGTACATGGA TTTTCCAGCATATTGCTTTAAAAAATTATATAAACTGTTAAAATATTAACACCTCAGGCT ACCTGCTGTATTCTGTCCCATTGACCCCTGGAATTGGATTTACTGCAAGTGATTGATAAT TCAATTATGTGGCTTTTCCCCTTTAATCTTGCCATTTAAATTACAGTAGAAAGACAAAAT CAAGTAAAATAAAGTGTTAGATAATAGAAAGAGTGTTAAGACCAGCCCACTTTTCTCATG TTTATGTTCTTTCATTTGGACCAAGAATCTCCGCATGGAGGTTGATTTGCCACTGGGGAC TTTGGCTAAGACTATTAGGTTTGCTTTCAACTAGATGTTCCTGAGACAAGCAGAGGGACA CTGCAATTCCCCTTCCATGCCTGCTGTTCTCCCCCATGTAAGTCTTCTTTGAAATTAACG GATGTGTCTCCTTTGGAACAGCCCCATAACAAAAGAGAACTACTGATCTGAGCATAGGAA AGTAGAGGCTCTACCACTTTTCAGTTGAAAAAGCAAGACTTTCTCTGTGTTTCTGAAACA AGGCATAATGTTGTCACAGAATCAGAGATCCAGTCTCACTTTTCCACAAATCTCCAAATC TCCAGTCTTATCTTGTGTGCTCTAATGGTTTGGTTCAATCCCTTTCCAACTCTTGTTTTC AAAGCATGGGGCCTGAGTGTTCTCCACTCCTCCTAAGAAAGGAGCTTGGGTGGAAGGGAC CATGCTGACCTCCTCCATCAGAGGGCTCTTCCAGTAGTATTCTCGGATGCAACCTCCATT TCTCAGTTACCATTATTTCCTGTATCAGCTTTGTCCTTCCTGGAGGGATGCACAGTGATC CGGCCCACCACTGTTGTTGTCTTGTGCTTCTGCTCTTTCCTATGGTTTCAGGTTATTTTC TGGGTTTCCCCTATTCTTCTTTTATTTCTTTTTTTTTTTATATTTGCTTTCCTTTCTACT GCTTTTAGATTTGCAGGAGATGCAAGTTTCAGCTCAATGTTTGGCTTCTCTCAATATGGA AATTTCAGAAGGACAGAGGAGAGGAGGGAGGAAGAAGAAAGTATACTCCTCCAGAATTTC AGTGATCTGTTGTGGCAGTCCAGTGGAAGGAAGGTCTTTTGAGGTCACTTAGAAGCATCT TTTTGGGACATCCTTTTGGGATCTCTGTAGGCTAGGCATCTCATATCTTGAGACTCACCC CCAGCCTCCAAGCCTCTCTCCATTTCTCTAACCTATGCATTTTAGAGCGAGAGGACCGCC TCACTAGTGTCACCATCCTGCCTTTTCTAAAACATGCAGGCTCACACATTCTACTCCTGC TTAATGTCTGTGTTAAACGTTTTCTAACCATTTTTGTTTTATTTTTCTGAAAAAGTTAAC CCCTCCCAACTCCTCACACATTGGCTCTTCCTCTTGAGCCACAAAGTTTTGATTCTTGCG ATGTATGTGCCTTATTTTATGTTAATCTTGTCAATGAGAGGGACCAGTTGGTGTTGCCCA ATCAGCACTCCAAGGCTGTGTGTGCACCAGCCAGAGAGCGCACGGTGGTAGCAGAGTCGA GGCTGTCTTGTATCCTGGTTTCATGTGTTGTTTTGAACTGATAGGAGGATGTTCTCTTCT GACAAGTTACCCTTGTGTATCCTGCAGACATGTAAAATAAAATACAAGTTCATTTTTTTC ACCTTTTTTAGATTTTTTTAAAAAATAAAATGTGTAATCCTTTTTTTAAAAGAAACACAT GTAAATACATTTAAGTATTGTAGGCATAGCGTTCAGATGTGACTGGCCCAGGCGTTCCTC GGACAAGCCTGCATTCCCCGTGATCACGCCCACCTCAAGCCCAGGGGCTGCAGCCCAGCC ACAGATGAACTCTACCTTTGCTTTCAGAACCACTTAGTCCTTTTGTAACAAAGAAAAAAA AATGTTTCTTACAATGTCAATAAAAAATTCTTTGTATGGAAA |
Protein Sequence | >2737 : length: 1580 MEAQSHSSTTTEKKKVENSIVKCSTRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITM QPQNVQGLSKVSEEPSTSSDERASLIKKEIHGSLPHVAEPSVPYRGTVFAMDPRNGYMEP HYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHR NPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRGLSPTDAPHAGVSPAEYYHQ MALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLS DHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMH QQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSE SAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYET NCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRH TGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRT HSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHS QSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPI SNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKL ERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTM LNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPIST DASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALL GDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPR VPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTM DADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAG QQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVH PQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNR QPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQDPVGQ GYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVV RGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYS GQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLE GVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIG DMSSLLTSLAEESKFLAVMQ |