| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2668 |
Name | GDNF |
Synonym | ATF1|ATF2|HFB1-GDNF|HSCR3;glial cell derived neurotrophic factor;GDNF;glial cell derived neurotrophic factor |
Definition | ATF|astrocyte-derived trophic factor|glial cell line-derived neurotrophic factor |
Position | 5p13.1-p12 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | TGF-beta signaling pathway;PANTHER;P00052 |
Pathway | Signaling events regulated by Ret tyrosine kinase;PID Curated;200058 |
Disease | Drug abuse;FunDO |
Disease | Neurofibromatosis;FunDO |
Disease | Neuroblastoma;FunDO |
Disease | PSYCH;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | Neurodegenerative disorder;FunDO |
Disease | Hirschsprung disease;OMIM |
Disease | Major depressive disorder;NHGRI |
Disease | Huntington disease;FunDO |
Disease | Lung cancer;FunDO |
Disease | Retinal disease;FunDO |
Disease | Pancreas cancer;FunDO |
Disease | schizophrenia;GAD |
Disease | Schizophrenia;FunDO |
Disease | major depressive disorder;GAD |
Disease | Central hypoventilation syndrome;OMIM |
Disease | Pheochromocytoma, modifier of;OMIM |
External Links | |
Links to Entrez Gene | 2668 |
Links to all GeneRIF Items | 2668 |
Links to iHOP | 2668 |
Sequence Information | |
Nucleotide Sequence | >2668 : length: 3830 CCAAAGCGTCCGAGACTGGGTACAGTCGTCCAGGCGTGACGGGGGCGCGGGGAGCCAGTG ACTCCTCTGGGAGGGGAAGGGATTAGGGCCAGAATCTCTCAAAGGTGCAAAAATCCAGTC AAGAGAGGGTTTTCGGGTATACCACGGAGGATTAAAACTTTCAAGACAAATGCAGTCTTT GCCTAACAGCAATGGTGCCGCCGCCGGACGGGACTTTAAGATGAAGTTATGGGATGTCGT GGCTGTCTGCCTGGTGCTGCTCCACACCGCGTCCGCCTTCCCGCTGCCCGCCGGTAAGAG GCCTCCCGAGGCGCCCGCCGAAGACCGCTCCCTCGGCCGCCGCCGCGCGCCCTTCGCGCT GAGCAGTGACTCAAATATGCCAGAGGATTATCCTGATCAGTTCGATGATGTCATGGATTT TATTCAAGCCACCATTAAAAGACTGAAAAGGTCACCAGATAAACAAATGGCAGTGCTTCC TAGAAGAGAGCGGAATCGGCAGGCTGCAGCTGCCAACCCAGAGAATTCCAGAGGAAAAGG TCGGAGAGGCCAGAGGGGCAAAAACCGGGGTTGTGTCTTAACTGCAATACATTTAAATGT CACTGACTTGGGTCTGGGCTATGAAACCAAGGAGGAACTGATTTTTAGGTACTGCAGCGG CTCTTGCGATGCAGCTGAGACAACGTACGACAAAATATTGAAAAACTTATCCAGAAATAG AAGGCTGGTGAGTGACAAAGTAGGGCAGGCATGTTGCAGACCCATCGCCTTTGATGATGA CCTGTCGTTTTTAGATGATAACCTGGTTTACCATATTCTAAGAAAGCATTCCGCTAAAAG GTGTGGATGTATCTGACTCCGGCTCCAGAGACTGCTGTGTATTGCATTCCTGCTACAGTG CAAAGAAAGGGACCAAGGTTCCCAGGAAATGTTTGCCCAGAATGGAAGATGAGGACCAAG GAGGCGGAGGAGGAGGAAGAAGAAGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAA GGCAGCCATCATGGGAGCCTGGTAGAGGGAGATCCAGCTACAGACAACTGGACAGGAGAG AGAGAAAACAGCCCTCTGGATTCTCCAGGATGGCAGCCGATGTCACTAGAAGCTCAGGGC TGATGTTCCTGGTTGGCTATTGCCACCATTTCAGCTGATACAGTCCACCATCACTGATTA CCGGCGCGGTTGCGGTGGATGCACTTGAACCAAACCAGTGTATCTCCTGTGATTTGTTTT CATGTGTCCGAAGACACCAGGGAAACAGAGATCCTGGTGTTGTTCCTTGTTATTACGTTT TACTGCTGAAAGTAAGAGGTTTATTTTTCTGTCACTCAGTGGAGACATACCCTGGAAAGG AGAGGGGAAAAAAAAAGCAAAGATACAAGAGATAATCACCTTTGCATTTGAAAGTTGAGG CCCGAGGTTTACTACAACCAGCATTTTTGCCAACGGTTGGTGATTGATTTCCATCACGGT GTGTGGGGTGGGAAGAAGTTGGCTAGGAACCAAAAAGGCTGTGCTCATGATTAAACACAA ACCTGAAGGTATTTCCTTTATGTCCTTGGAAACAGGAAACGAGTTGTGGTTTTCGCCAGC ATTCTTGTAGGAGAGAATCGGGGAAGGCCCCGAACTGCCCCCGGGCAGGGAGAGCCCCTC AGGCCTGTTGGTTTACAGAGAGACAGATGTTACATAACCAGCTCCGTTGATGCGTGGTCA CCAGTGACCAGAGAAGCTACTCGATGCAATGCATCTGTTTCAGATACAGAAATATAGAGA AGATATTTATTGAAATTTAAGTTATTGTTATTTATTACCGTTCACTAATGAATTTCTCTT TTTTCCCTTATTTATTAAAGTTTCTTTTCAAAGGTGCCAAAGTATATGTGCTCGCAAAAT GCAAAGAAAGGTGACAAAAGGAAATTTGAATTGGGAACAAGGGTCCATGCTTTTCAAAGT ATTAAAAAGTTTTTTGCCAGGCAAAAATCACTTACTTTACCTTTTTAAGAAAATTTGTCA TTAATTTTCCCCAGATTTCAGCATTTTTCCCAATTTTTATTTGTGGAGCATCTCAGGCAA GCCCCCTTTCCTGGAGCAGCGTGCAGAGACCACTGGCACTTGACTTTATTTCTTCCTTGC TCCATTGCTGAACAGAAATGTCGTGGGCTCCACTTCCTGTTGTCTTTAAGCTCTTAGTCC CCTCCACGTATACCTATCTGTACTATGCATAACCATATGTAGAAAAGGTTCAGTTCCTTT TAGTAGGTAGTCCTGGATTTAATGCTGACCTAAAAGTAATGTCGACAATGCTGTCAGGTA GCTGCCGTTCTACCGACTCCCTCCATCCCTGCCCACCCACTGCCCTCCCGAGAATATGCT GGCTGCCCAGTGCAGCCCGGGAGACACAGGGGCCTTCCAGAGGTAGGGTCTACCAGGTCC TGTACAACCCCTGGGCTGTCACCGGGGGTCAACAGCTGCTGCTCCTATATACCCAAACAC CTGACAGCTCCCTGGGGAGCAGATGGCTGAGAAGGGTGCTGAGGAAGCCATATTGGGACC AGCCACAGCCACACACATGGAGCCTCATACTTAGGAGCGTGCTGCCTTTAAATGAAGGTG GTCGGGGCCAGTGCAGCGGCTCACACCCATAATCCCAACACTTTGGAAAGCCAAGGTGGG AGGATCTCTTGAACCCAGGAGTTTGAGACCAGCTTGGGCAACATAGGGAGACCCTGTCTC TACAGAAACTTTAAAAATTAGGCAGGCATGATGGTGCACACCTGTGGTCCCAGCTACTCA AGAGGCTGAAGGAGGATCACTTGAGTCCAGAAGGTCGAGGCTGCAGTGAGCTGTGATCAT GCCACTGCACTCCAGCCTAAGTGACAGTGCGGTACCCTGTCTCAAAAAAAAAAAAAAAAA AAAAAAGAGGTTGGAGCAGGAGGAAGCATAGGGGCGGGAACAGCCACCTCCTCCATGCCC TAGATTGTGAATTTATCGGGCAGCCAACACATGTATGACACACTAGGCCCTGTATTACAG CTTGTTACGCATTTCATAAAAGGGATTTTCATTAAGGAGATAATCTATTACTACCTACCT TAGTGGCTACTAGTATAAAACTATGACAGATTTAGCAATTAAATGAAATACTGGCCTCCA TCAAATAATCATAGTAACAAGAAGCAGCAGTTACCAGACATCTGATCCCCTTCCCCCAAA ATACCCAAATTCTTCATGGTTCTGCCCTTCTCTGTCCTTTCTGCTCCCCTTGCTCGCCTG GGAAATGGAGGAAAGGCCTTCCCTCTCACACTGTCTTGGGATCTTGCTGAGAATTCAGAC TGCTCGAAACAGTGACAAACCCCAGCCATCCAGTCATTCGTGGAGCACAATTTGGATGTG GCCCCAGGGGCATCTGTCCCATTCAGAGAACCTTGGCAGTGCGATGGCCACTGTTCCCAG GCTTCAACCTCAGTGACCCCCCCCAACAACTCCCCATGGAGAGTCCCTGCCCAAAAAAGC TGTAGGATCCAAGGGGTGTCAATAGCTCGTTCCCGGCATCACCTACACACCACAAGCAGG TTTTAATGGAAGCAAGTTGCTCCACCAAATCCACAAAAGGGTAAAGTTTGTGATTTTTCT TTATCATTGCGATCACCATCTGATACCGTAAGGAGTGCACTTGTTTGGAAGTTCTGACTT CTCTGATCTGTCTTGGTCGTTTGTGTTATAAAACCAAAGTTCTCTACAGACTTTATTTTT GTACAATATCATTTTGTAACTTTTTACAAATAAAAACTCATTTCTATTGC |
Protein Sequence | >2668 : length: 228 MQSLPNSNGAAAGRDFKMKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRA PFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI |