| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 26524 |
Name | LATS2 |
Synonym | KPM;large tumor suppressor kinase 2;LATS2;large tumor suppressor kinase 2 |
Definition | LATS (large tumor suppressor, Drosophila) homolog 2|LATS, large tumor suppressor, homolog 2|kinase phosphorylated during mitosis protein|large tumor suppressor homolog 2|serine/threonine kinase KPM|serine/threonine-protein kinase LATS2|serine/threonine-pr |
Position | 13q12.11 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Coregulation of Androgen receptor activity;PID Curated;200038 |
Disease | Brain tumor;FunDO |
Disease | Breast cancer;FunDO |
Disease | Lung cancer;FunDO |
Disease | Prostate cancer;FunDO |
External Links | |
Links to Entrez Gene | 26524 |
Links to all GeneRIF Items | 26524 |
Links to iHOP | 26524 |
Sequence Information | |
Nucleotide Sequence | >26524 : length: 5581 ATTCCCGTGCCCTAGTTTAGCGACGTGTGGGGGGTTTGGCTTTCTCTTCTGATGTAAGCT CACCTGCGCTTAGCTCCCCAGCCGGACTCTGGAGATGGGGATTCTGACATCATTCACATC TTGCCATCACATCCTTCAGCCCAACTCCAGAACTTCTGGGGAGCTTTCCCTCGGGGATGG AGTGCGGCCTGGAGCAAACCCGTTTGTGAAATGCAAGTCTCCAGTGTCCCGAGGGTTGGG AACGGGGGGCGAGGCGAGGAATGGACCCTGAAGAAGAGAGTGATAATCTTCAAAATGAAG ACTTTGGAAAATTTTAGGTTCTCTATAGGAACTACAAAAATGGAAGGAAAGAACATTTTC AAAAGGAAATTATTTTGAAAGTATGTTTACAACAAACTGATACTATTGACAGTTTTTTTT TTTAAATAATAAAACACTTTAAGAAGATTGTATTTATGGTAAAAGGAAACTGGACTAACA ATGAGGCCAAAGACTTTTCCTGCCACGACTTATTCTGGAAATAGCCGGCAGCGACTGCAA GAGATTCGTGAGGGGTTAAAACAGCCATCCAAGTCTTCGGTTCAGGGGCTACCCGCAGGA CCAAACAGTGACACTTCCCTGGATGCCAAAGTCCTGGGGAGCAAAGATGCCACCAGGCAG CAGCAGCAGATGAGAGCCACCCCAAAGTTCGGACCTTATCAGAAAGCCTTGAGGGAAATC AGATATTCCTTGTTGCCTTTTGCTAATGAATCGGGCACCTCTGCAGCTGCAGAAGTGAAC CGGCAAATGCTGCAGGAACTGGTGAACGCAGGATGCGACCAGGAGATGGCTGGCCGAGCT CTCAAGCAGACTGGCAGCAGGAGCATCGAGGCCGCCCTGGAGTACATCAGCAAGATGGGC TACCTGGACCCGAGGAATGAGCAGATTGTGCGGGTCATTAAGCAGACCTCCCCAGGAAAG GGGCTCATGCCAACCCCAGTGACGCGGAGGCCCAGCTTCGAAGGAACCGGCGATTCGTTT GCGTCCTACCACCAGCTGAGCGGTACCCCCTACGAGGGCCCAAGCTTCGGCGCTGACGGC CCCACGGCGCTGGAGGAGATGCCGCGGCCGTACGTGGACTACCTTTTCCCCGGAGTCGGC CCCCACGGGCCCGGCCACCAGCACCAGCACCCACCCAAGGGCTACGGTGCCAGCGTAGAG GCAGCAGGGGCACACTTCCCGCTGCAGGGCGCGCACTACGGGCGGCCGCACCTGCTGGTG CCTGGGGAACCCCTGGGCTACGGAGTGCAGCGCAGCCCCTCCTTCCAGAGCAAGACGCCG CCGGAGACCGGGGGTTACGCCAGCCTGCCCACGAAGGGCCAGGGAGGACCGCCAGGCGCC GGCCTCGCTTTCCCACCCCCTGCCGCCGGGCTCTACGTGCCGCACCCACACCACAAGCAG GCCGGTCCCGCGGCCCACCAGCTGCATGTGCTGGGCTCCCGCAGCCAGGTGTTCGCCAGC GACAGCCCCCCGCAGAGCCTGCTCACTCCCTCGCGGAACAGCCTCAACGTGGACCTGTAT GAATTGGGCAGCACCTCCGTCCAGCAGTGGCCGGCTGCCACCCTGGCCCGCCGGGACTCC CTGCAGAAGCCGGGCCTGGAGGCGCCGCCGCGCGCGCACGTGGCCTTCCGGCCTGACTGC CCAGTGCCCAGCAGGACCAACTCCTTCAACAGCCACCAGCCGCGGCCCGGTCCGCCTGGC AAGGCCGAGCCCTCCCTGCCCGCCCCCAACACCGTGACGGCTGTCACGGCCGCGCACATC TTGCACCCGGTGAAGAGCGTGCGTGTGCTGAGGCCGGAGCCGCAGACGGCTGTGGGGCCC TCGCACCCCGCCTGGGTGCCCGCGCCTGCCCCGGCCCCCGCCCCCGCCCCCGCCCCGGCT GCGGAGGGCTTGGACGCCAAGGAGGAGCATGCCCTGGCGCTGGGCGGCGCAGGCGCCTTC CCGCTGGACGTGGAGTACGGAGGCCCAGACCGGAGGTGCCCGCCTCCGCCCTACCCGAAG CACCTGCTGCTGCGCAGCAAGTCGGAGCAGTACGACCTGGACAGCCTGTGCGCAGGCATG GAGCAGAGCCTCCGTGCGGGCCCCAACGAGCCCGAGGGCGGCGACAAGAGCCGCAAAAGC GCCAAGGGGGACAAAGGCGGAAAGGATAAAAAGCAGATTCAGACCTCTCCCGTTCCCGTC CGCAAAAACAGCAGAGACGAAGAGAAGAGAGAGTCACGCATCAAGAGCTACTCGCCATAC GCCTTTAAGTTCTTCATGGAGCAGCACGTGGAGAATGTCATCAAAACCTACCAGCAGAAG GTTAACCGGAGGCTGCAGCTGGAGCAAGAAATGGCCAAAGCTGGACTCTGTGAAGCTGAG CAGGAGCAGATGCGGAAGATCCTCTACCAGAAAGAGTCTAATTACAACAGGTTAAAGAGG GCCAAGATGGACAAGTCTATGTTTGTCAAGATCAAAACCCTGGGGATCGGTGCCTTTGGA GAAGTGTGCCTTGCTTGTAAGGTGGACACTCACGCCCTGTACGCCATGAAGACCCTAAGG AAAAAGGATGTCCTGAACCGGAATCAGGTGGCCCACGTCAAGGCCGAGAGGGACATCCTG GCCGAGGCAGACAATGAGTGGGTGGTCAAACTCTACTACTCCTTCCAAGACAAAGACAGC CTGTACTTTGTGATGGACTACATCCCTGGTGGGGACATGATGAGCCTGCTGATCCGGATG GAGGTCTTCCCTGAGCACCTGGCCCGGTTCTACATCGCAGAGCTGACTTTGGCCATTGAG AGTGTCCACAAGATGGGCTTCATCCACCGAGACATCAAGCCTGATAACATTTTGATAGAT CTGGATGGTCACATTAAACTCACAGATTTCGGCCTCTGCACTGGGTTCAGGTGGACTCAC AATTCCAAATATTACCAGAAAGGGAGCCATGTCAGACAGGACAGCATGGAGCCCAGCGAC CTCTGGGATGATGTGTCTAACTGTCGGTGTGGGGACAGGCTGAAGACCCTAGAGCAGAGG GCGCGGAAGCAGCACCAGAGGTGCCTGGCACATTCACTGGTGGGGACTCCAAACTACATC GCACCCGAGGTGCTCCTCCGCAAAGGGTACACTCAACTCTGTGACTGGTGGAGTGTTGGA GTGATTCTCTTCGAGATGCTGGTGGGGCAGCCGCCCTTTTTGGCACCTACTCCCACAGAA ACCCAGCTGAAGGTGATCAACTGGGAGAACACGCTCCACATTCCAGCCCAGGTGAAGCTG AGCCCTGAGGCCAGGGACCTCATCACCAAGCTGTGCTGCTCCGCAGACCACCGCCTGGGG CGGAATGGGGCCGATGACCTGAAGGCCCACCCCTTCTTCAGCGCCATTGACTTCTCCAGT GACATCCGGAAGCAGCCAGCCCCCTACGTTCCCACCATCAGCCACCCCATGGACACCTCG AATTTCGACCCCGTAGATGAAGAAAGCCCTTGGAACGATGCCAGCGAAGGTAGCACCAAG GCCTGGGACACACTCACCTCGCCCAATAACAAGCATCCTGAGCACGCATTTTACGAATTC ACCTTCCGAAGGTTCTTTGATGACAATGGCTACCCCTTTCGATGCCCAAAGCCTTCAGGA GCAGAAGCTTCACAGGCTGAGAGCTCAGATTTAGAAAGCTCTGATCTGGTGGATCAGACT GAAGGCTGCCAGCCTGTGTACGTGTAGATGGGGGCCAGGCACCCCCACCACTCGCTGCCT CCCAGGTCAGGGTCCCGGAGCCGGTGCCCTCACAGGCCAATAGGGAAGCCGAGGGCTGTT TTGTTTTAAATTAGTCCGTCGATTACTTCACTTGAAATTCTGCTCTTCACCAAGAAAACC CAAACAGGACACTTTTGAAAACAGGACTCAGCATCGCTTTCAATAGGCTTTTCAGGACCT TCACTGCATTAAAACAATATTTTTGAAAATTTAGTACAGTTTAGAAAGAGCACTTATTTT GTTTATATCCATTTTTTCTTACTAAATTATAGGGATTAACTTTGACAAATCATGCTGCTG TTATTTTCTACATTTGTATTTTATCCATAGCACTTATTCACATTTAGGAAAAGACATAAA AACTGAAGAACATTGATGAGAAATCTCTGTGCAATAATGTAAAAAAAAAAAAAGATAACA CTCTGCTCAATGTCACGGAGACCATTTTATCCACACAATGGTTTTTGTTTTTTATTTTTT CCCATGTTTCAAAATTGTGATATAATGATATAATGTTAAAAGCTGCTTTTTTTGGCTTTT TGCATATCTAGTATAATAGGAAGTGTGAGCAAGGTGATGATGTGGCTGTGATTTCCGACG TCTGGTGTGTGGAGAGTACTGCATGAGCAGAGTTCTTCTATTATAAAATTACCATATCTT GCCATTCACAGCAGGTCCTGTGAATACGTTTTTACTGAGTGTCTTTAAATGAGGTGTTCT AGACAGTGTGCTGATAATGTATTGTGCGGGTGACCTCTTCGCTATGATTGTATCTCTTAC TGTTTTGTTAAAGAAATGCAGATGTGTAACTGAGAAGTGATTTGTGTGTGTGTCTTGGTT GTGATTGGATTCTTTGGGGGGGGGGAACTGAAACATTTGTCATATACTGAACTTATATAC ATCAAAAGGGATTAATACAGCGATGCCAAAAAGTTTAATCACGGACACATGTCCGTTTCT GTAGTCCGTATGCTCTTTCATTCTTGGTAGAGCTGGTATGTGGAATGCCATACCTCTGAC CCTACTACTTACCTTTTTACTGACAGACTGCCCACACTGAAAGCTTCAGTGAATGTTCTT AGTCCTGTTTTCTTCTGTTACTGTCAGGAAACTGAGTGATCTAATGGTTCTCTCACTTTT TTTTTGTTCTTTTAGTGTACTTTGAAGTATCAAATCTTAACTTGGTTTAAACAATACATA TTCCTAACCTTTGTAAAAAAGCAAAGATTCTTCAAAATGACATTGAAATAAAAAGTAAGC CATACGTATTTTCTTAGAAGTATAGATGTATGTGCGTGTATACACACACACACACACACA CAGAGATAAACACAATATTCCTTATTTCAAATTAGTATGATTCCTATTTAAAGTGATTTA TATTTGAGTAAAAAGTTCAATTCTTTTTTGCTTTTTAAAAAATCTGATGCTTCATAATTT TCATTATATTATTCCACATATTTTTCCTTGAAGTTCTTAGCATAATGTATCCATTACTTA GTATATATCTAGGCAACAACACTTAGAAGTTTATCAGTGTTTAAACTAAAAAAATAAAGA TTCCTGTGTACTGGTTTACATTTGTGTGAGTGGCATACTCAAGTCTGCTGTGCCTGTCGT CGTGACTGTCAGTATTCTCGCTATTTTATAGTCGTGCCATGTTGTTACTCACAGCGCTCT GACATACTTTCATGTGGTAGGTTCTTTCTCAGGAACTCAGTTTAACTATTATTTATTGAT ATATCATTACCTTTGAAAAGCTTCTACTGGCACAATTTATTATTAAAATTTTGAATCCAA A |
Protein Sequence | >26524 : length: 1088 MRPKTFPATTYSGNSRQRLQEIREGLKQPSKSSVQGLPAGPNSDTSLDAKVLGSKDATRQ QQQMRATPKFGPYQKALREIRYSLLPFANESGTSAAAEVNRQMLQELVNAGCDQEMAGRA LKQTGSRSIEAALEYISKMGYLDPRNEQIVRVIKQTSPGKGLMPTPVTRRPSFEGTGDSF ASYHQLSGTPYEGPSFGADGPTALEEMPRPYVDYLFPGVGPHGPGHQHQHPPKGYGASVE AAGAHFPLQGAHYGRPHLLVPGEPLGYGVQRSPSFQSKTPPETGGYASLPTKGQGGPPGA GLAFPPPAAGLYVPHPHHKQAGPAAHQLHVLGSRSQVFASDSPPQSLLTPSRNSLNVDLY ELGSTSVQQWPAATLARRDSLQKPGLEAPPRAHVAFRPDCPVPSRTNSFNSHQPRPGPPG KAEPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVPAPAPAPAPAPAPA AEGLDAKEEHALALGGAGAFPLDVEYGGPDRRCPPPPYPKHLLLRSKSEQYDLDSLCAGM EQSLRAGPNEPEGGDKSRKSAKGDKGGKDKKQIQTSPVPVRKNSRDEEKRESRIKSYSPY AFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKR AKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDIL AEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIE SVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSD LWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVG VILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLG RNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEESPWNDASEGSTK AWDTLTSPNNKHPEHAFYEFTFRRFFDDNGYPFRCPKPSGAEASQAESSDLESSDLVDQT EGCQPVYV |