| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 25970 |
Name | SH2B1 |
Synonym | PSM|SH2B;SH2B adaptor protein 1;SH2B1;SH2B adaptor protein 1 |
Definition | SH2 domain-containing protein 1B|SH2 domain-containing putative adapter SH2-B|SH2-B signaling protein|SH2B adapter protein 1|pro-rich, PH and SH2 domain-containing signaling mediator |
Position | 16p11.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Disease | body fat leptin;GAD |
Disease | Body mass index;GAD |
Disease | Weight;NHGRI |
Disease | Body mass index;NHGRI |
Disease | weight;GAD |
Disease | METABOLIC;GAD |
External Links | |
Links to Entrez Gene | 25970 |
Links to all GeneRIF Items | 25970 |
Links to iHOP | 25970 |
Sequence Information | |
Nucleotide Sequence | >25970 : length: 4876 CGCGACCCGGCCCTGGCGCCCGAGAGGATTCCTGGGTGGGGGTGGGCGTGGAGGGCCGGG GGCTGGAGAGGCACTCGGCCCCGGAGAGTGCAGCAGACAGGGCTGGTCCCGAGGTGGATG CGGCCCCGGAAAATGGGCGGCTGGGGGGTGTCCAGGGAGTAGGGTCGGATCGGAGTATAT GGACCACCGGGCCCGGAGGGTCCGAGCCGAGAGCGGAGCCTGCACCCTCCACCTCCCGCC CTTCGGGAAATATCAGAACTGAGCCAGGAGGCAGGTGCACCGGGAAAATGTGTCTGAGTC CTGCTTGGCAGAAGAGAAACTGAGTCACCAGCTTAGGAGTCGCAGGGTCAGCGGGCCTGA AGGGGGCTGGGTCTGTCTGCGGTGCGGAGGATTGGGTGGGCCTGTGTGAGCCGAGGTGGC CGCTGGCTGGAGATTGGTTTGCACTTCTTGGCTGGGTTCCCCCGTGCTCCATGACTCCTG CATCTCCTGATTGTTTCTCGTTGGTTTGGAGTTGTCCCTGCGGTTGGAGCCATCTGAGCT TGTAGGGTCGAGGCCCAGGAGGAAGGGGAGGGTTCACCGACTTACAGCCTGGCTGTAGGT TTGAACAGGAGTCTGAGGTCGCTGAGGGTTTGGGGAGGCTTTCCTGAGCTGCTCTGGCCC CAGTCCTGGGGCTGTCACCTTCCAGTATTGCGTGGCGGGAGGAGCGCTAACAAGAGCCAA GGGTTGTAAATTCCACACCCAGCTCTGCCACTTTCTAGTTGTAAGACCTTGAGAGGGCTC CTCCTTTCTCTAATTTCTATTTTAGAAAATTGGAACAATAATATTCTTCTCCCACATGAA GATAGTAACAATGGCAGTCGTTCAGCGGATGCTTACTTTGCGTTCAGCGCTGACATACCC CATTCCATGTAATTCTCTCAACATTTCGAGGGGAGGGATCATTAGCTTTGTTTAACAGAT AGAAAAACGGAGGCTCAGAGAGGACGTGGAATTTGTTCAAGATAACATCGCTCATAAGGT GGCTGGACTGGGTGCTCATAAGGTGGTTTGAGCCCTGGTCTGACTCAAGTCCATGGCCTT AACCAGAAGGCTAACCTGCCTTTAGGGCATACTCCCCAGTGGGAGAAGAGGAAGGTGAAA AATCCTAGGGCCCCAGCTCTCCCTGTGATGTTTTGTTTACGTGAGGCCAGCAAAGACTTG ACCTGAGCCAACCCAGTTTCTCCTCTGGGGCCCCTGCGGCCTCTGGCCCCAGACTGAAGG GATACCAAAGAAGTGGGCTGTAGCTATTTCACATCTCCTTCACGCAGTGCGTGGGTGCTG GACTCTGGGGTCAGCTTTCAAGACAATTACTGTTTTGGTCCATCATGCATCCATCCTCAT TAATGAATCGGCCCCCTCCAAAGAGTTGGACCCTAAGATGCGTGAGGCAGGCTCTCTAAG GTCTAGAATCCCAGCTCCTCTCTAGCCCCCTGCGAGCTGGGGCGGTGAGGTGCTATGGCT GAGGCTGGCCCAGCCGGGCCCTGGGGACAGGGACTATGAAGTGGGGAAAACAGTAGACTT GGAGTTCTGAAACTTTTCTGAGCTTCGGTTTCCTCATCTGTTCGAGAGGTCTTTGAAACC TCTCAGGGAAAGGTAAGATAACCAAGTGGGAGCCTCTAGAATGGCTCATGGGAAGTGTGA CATGAATATTGGAGGATCCGATGTAGAGGGGGGGTGATCTGGAAAAGTTCCCTTTTTTAG GGGGAAGGTGCTCCAAAGCCCTCTACTGCTGGATCCAAAGCTAAGGAAAGTGGGGGCAAA TGTGGCAGGCTCGGGGCAGGTTAGACGCTGGGGAGCCAGTTGGCTGGGGCCTGCAGGGTG CCAGGATCTGGGAGAGGGAAGGGAGGTGTTGGGCTCCCTTCCCCATTGCTCTCTGCGGAG TCTGAAGTAGGGTCGGACGTCTCTGGCTGGGGGTGGGATGCAGCCTCCGGTGCGCCCTCA GCAGTGACCCTCGTGTGTGCCTCTCTCTTCCTTTCGCAGCTGCTGCCGCCCACCCCTCGT CTTCTGGCTGCCTCCCTCTTTGTGCCCCACAGGCTCCCCCTCTCCACCTCCTGGGGCCCA TCATGAATGGTGCCCCTTCCCCAGAGGACGGGGCCTCCCCCTCGTCTCCCCCGCTGCCCC CACCCCCGCCCCCTAGTTGGCGGGAGTTCTGTGAGTCCCACGCCCGGGCTGCGGCTCTGG ACTTTGCCCGCCGTTTTCGCCTCTACCTGGCCTCCCACCCCCAATATGCGGGGCCCGGGG CCGAGGCTGCCTTCTCCCGCCGTTTTGCTGAGCTCTTCCTGCAGCACTTTGAAGCCGAGG TGGCCCGGGCCTCTGGCTCCCTGTCGCCACCCATCCTGGCTCCCCTGAGCCCTGGTGCGG AGATTTCGCCACATGACCTGTCCCTTGAGAGCTGCAGGGTGGGTGGGCCCCTGGCTGTGC TGGGCCCTTCTCGATCATCTGAGGACCTGGCCGGCCCCCTCCCTTCCTCAGTCTCTTCCT CCTCTACAACCTCCTCCAAGCCGAAGCTCAAGAAGCGCTTTTCCCTGCGTTCAGTGGGTC GCTCTGTCCGAGGCTCAGTCCGTGGCATCCTGCAGTGGCGGGGGACCGTTGACCCTCCCT CCTCCGCTGGGCCCCTGGAGACCTCGTCAGGCCCCCCAGTCTTAGGTGGAAACAGCAACT CCAACTCCTCTGGCGGGGCTGGGACCGTTGGTAGGGGACTGGTCAGTGATGGAACGTCCC CTGGGGAAAGATGGACTCACCGTTTTGAGAGGCTGAGACTCAGTCGGGGAGGGGGCGCCT TGAAGGATGGAGCAGGGATGGTGCAGAGGGAAGAGCTGCTGAGTTTCATGGGGGCTGAGG AGGCAGCCCCTGACCCAGCCGGAGTGGGCCGGGGAGGAGGGGTGGCTGGGCCTCCTTCAG GGGGAGGAGGGCAGCCTCAGTGGCAGAAGTGTCGCCTGCTGCTTCGAAGTGAAGGAGAAG GAGGAGGAGGAAGTCGCCTGGAGTTCTTTGTACCACCCAAGGCCTCTCGGCCCCGACTCA GCATCCCCTGCTCTTCTATCACAGACGTCCGGACAACCACAGCCCTGGAGATGCCTGACC GGGAGAACACGTTTGTGGTTAAGGTGGAAGGTCCATCCGAGTATATCATGGAGACAGTGG ATGCCCAGCATGTGAAGGCCTGGGTGTCTGACATCCAAGAATGCCTGAGCCCAGGACCCT GCCCTGCTACCAGTCCCCGCCCCATGACCCTCCCTCTGGCCCCTGGGACCTCATTCCTTA CAAGGGAGAACACAGACAGCCTGGAGCTGTCCTGCCTGAATCACTCGGAGAGTCTACCCA GCCAGGACCTGCTGCTTGGACCCAGCGAGAGCAATGACCGCCTGTCGCAGGGGGCATATG GGGGCCTCTCAGACCGCCCCTCGGCATCCATCTCCCCCAGCTCTGCCTCCATTGCCGCCT CCCATTTTGACTCGATGGAACTGCTTCCCCCAGAGTTGCCCCCCCGCATCCCCATTGAAG AGGGACCCCCAACAGGGACAGTTCATCCCCTCTCAGCCCCCTACCCTCCCTTGGACACTC CGGAAACAGCCACAGGGTCCTTCCTGTTCCAGGGGGAGCCAGAGGGCGGTGAGGGGGACC AGCCCCTCTCAGGGTATCCTTGGTTCCACGGGATGCTCTCTCGGCTCAAGGCTGCACAGT TGGTGCTGACTGGCGGCACTGGCTCCCACGGTGTCTTCCTGGTGCGCCAGAGTGAGACAA GGCGGGGTGAATACGTCCTCACCTTCAACTTCCAGGGCAAGGCCAAGCACCTGCGTTTGT CGCTGAACGAGGAGGGTCAGTGCCGGGTCCAGCACCTGTGGTTCCAGTCCATTTTCGATA TGCTCGAGCACTTCCGGGTGCACCCCATCCCTTTGGAGTCGGGAGGCTCCAGTGATGTTG TCCTTGTCAGCTATGTCCCATCCTCCCAGCGACAGCAGGGCCGGGAGCAGGCTGGGAGCC ATGCGGGGGTGTGCGAGGGAGATGGATGCCACCCCGATGCCTCCTGCACCCTCATGCCCT TCGGAGCGAGTGACTGTGTAACCGACCACCTCCCATGACCCACCCCAGCCCCCTGAACCC CCTTCATGGACAGATCCCCCACAGCCTGGGGCAGAAGAGGCGTCGAGGGCGCCAGAAGTG GCGGCAGCAGCAGCCGCAGCAGCCAAAGAGAGGCAAGAGAAAGAGAAAGCGGGCGGTGGA GGGGTCCCGGAAGAGCTGGTCCCCGTGGTTGAGCTGGTCCCCGTGGTTGAATTGGAAGAG GCCATAGCCCCAGGCTCAGAGGCCCAGGGCGCTGGGTCTGGTGGGGACGCGGGGGTGCCC CCAATGGTGCAGCTGCAGCAGTCACCACTAGGGGGTGATGGAGAGGAAGGGGGCCACCCC AGGGCCATTAACAACCAGTACTCCTTCGTGTGAGCCAACCCCACCCGCTCCACCCTTTTT AAACCCCCCAGCCCTGCTCGTGAGATTGGGCTGGGTAGGGACAGAGGAGGCCGAAATCCC TCCCCCATGCTTCCTGACCCTTGTTGGCCAAGGGCATCTTTGATGGTACAAGCAGAGGCT CGGGAGAGGCTCCCGTCACACACTACAGGTCCCCTCCCCAGGGCAGGGGATTTGGGCTCC ATGAGCTCCTTGAGGGGCTCTTCTGGTCAGCCCCACCCTGGGGGCCATTTCCCCATTAAC TACCCCCAGCCCGAGGCAGGGTGAGGGGGAAGGGCTGTCAGTTACATTAAGGTGGTTGTT GTTGTTGTTTTAAACAAAATGGAGAAGCATAAATAAATAAAAAGGTTTATCTCGGTTCTA TCGTGAAAAAAAAAAA |
Protein Sequence | >25970 : length: 756 MNGAPSPEDGASPSSPPLPPPPPPSWREFCESHARAAALDFARRFRLYLASHPQYAGPGA EAAFSRRFAELFLQHFEAEVARASGSLSPPILAPLSPGAEISPHDLSLESCRVGGPLAVL GPSRSSEDLAGPLPSSVSSSSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGTVDPPS SAGPLETSSGPPVLGGNSNSNSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGAL KDGAGMVQREELLSFMGAEEAAPDPAGVGRGGGVAGPPSGGGGQPQWQKCRLLLRSEGEG GGGSRLEFFVPPKASRPRLSIPCSSITDVRTTTALEMPDRENTFVVKVEGPSEYIMETVD AQHVKAWVSDIQECLSPGPCPATSPRPMTLPLAPGTSFLTRENTDSLELSCLNHSESLPS QDLLLGPSESNDRLSQGAYGGLSDRPSASISPSSASIAASHFDSMELLPPELPPRIPIEE GPPTGTVHPLSAPYPPLDTPETATGSFLFQGEPEGGEGDQPLSGYPWFHGMLSRLKAAQL VLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDM LEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQEPTTSHDPPQPPEPPSWTDPPQPGAEEA SRAPEVAAAAAAAAKERQEKEKAGGGGVPEELVPVVELVPVVELEEAIAPGSEAQGAGSG GDAGVPPMVQLQQSPLGGDGEEGGHPRAINNQYSFV |