| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2521 |
Name | FUS |
Synonym | ALS6|ETM4|FUS1|HNRNPP2|POMP75|TLS;FUS RNA binding protein;FUS;FUS RNA binding protein |
Definition | 75 kDa DNA-pairing protein|RNA-binding protein FUS|fus-like protein|fused in sarcoma|fusion gene in myxoid liposarcoma|heterogeneous nuclear ribonucleoprotein P2|oncogene FUS|oncogene TLS|translocated in liposarcoma protein |
Position | 16p11.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | mRNA Splicing - Major Pathway;PID Reactome;500866 |
Pathway | Gene Expression;Reactome;REACT:71 |
Pathway | mRNA Processing;Reactome;REACT:1675 |
Disease | Amyotrophic lateral sclerosis;KEGG DISEASE;H00058 |
Disease | Cancers;KEGG DISEASE |
Disease | Amyotrophic lateral sclerosis 6, autosomal recessive;OMIM |
Disease | Cancers of soft tissues and bone;KEGG DISEASE |
Disease | Myxoid liposarcoma;KEGG DISEASE;H00049 |
Disease | Nervous system diseases;KEGG DISEASE |
Disease | Neurodegenerative diseases;KEGG DISEASE |
External Links | |
Links to Entrez Gene | 2521 |
Links to all GeneRIF Items | 2521 |
Links to iHOP | 2521 |
Sequence Information | |
Nucleotide Sequence | >2521 : length: 5119 ACTTAAGCTTCGACGCAGGAGGCGGGGCTGCTCAGTCCTCCAGGCGTCGGTACTCAGCGG TGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGAT TATACCCAACAAGCAACCCAAAGCTATGGGGCCTACCCCACCCAGCCCGGGCAGGGCTAT TCCCAGCAGAGCAGTCAGCCCTACGGACAGCAGAGTTACAGTGGTTATAGCCAGTCCACG GACACTTCAGGCTATGGCCAGAGCAGCTATTCTTCTTATGGCCAGAGCCAGAACACAGGC TATGGAACTCAGTCAACTCCCCAGGGATATGGCTCGACTGGCGGCTATGGCAGTAGCCAG AGCTCCCAATCGTCTTACGGGCAGCAGTCCTCCTACCCTGGCTATGGCCAGCAGCCAGCT CCCAGCAGCACCTCGGGAAGTTACGGTAGCAGTTCTCAGAGCAGCAGCTATGGGCAGCCC CAGAGTGGGAGCTACAGCCAGCAGCCTAGCTATGGTGGACAGCAGCAAAGCTATGGACAG CAGCAAAGCTATAATCCCCCTCAGGGCTATGGACAGCAGAACCAGTACAACAGCAGCAGT GGTGGTGGAGGTGGAGGTGGAGGTGGAGGTAACTATGGCCAAGATCAATCCTCCATGAGT AGTGGTGGTGGCAGTGGTGGCGGTTATGGCAATCAAGACCAGAGTGGTGGAGGTGGCAGC GGTGGCTATGGACAGCAGGACCGTGGAGGCCGCGGCAGGGGTGGCAGTGGTGGCGGCGGC GGCGGCGGCGGTGGTGGTTACAACCGCAGCAGTGGTGGCTATGAACCCAGAGGTCGTGGA GGTGGCCGTGGAGGCAGAGGTGGCATGGGCGGAAGTGACCGTGGTGGCTTCAATAAATTT GGTGGCCCTCGGGACCAAGGATCACGTCATGACTCCGAACAGGATAATTCAGACAACAAC ACCATCTTTGTGCAAGGCCTGGGTGAGAATGTTACAATTGAGTCTGTGGCTGATTACTTC AAGCAGATTGGTATTATTAAGACAAACAAGAAAACGGGACAGCCCATGATTAATTTGTAC ACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTTGATGACCCACCT TCAGCTAAAGCAGCTATTGACTGGTTTGATGGTAAAGAATTCTCCGGAAATCCTATCAAG GTCTCATTTGCTACTCGCCGGGCAGACTTTAATCGGGGTGGTGGCAATGGTCGTGGAGGC CGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGCAGTGGTGGTGGT GGCCGAGGAGGATTTCCCAGTGGAGGTGGTGGCGGTGGAGGACAGCAGCGAGCTGGTGAC TGGAAGTGTCCTAATCCCACCTGTGAGAATATGAACTTCTCTTGGAGGAATGAATGCAAC CAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGCTCTCACATGGGG GGTAACTACGGGGATGATCGTCGTGGTGGCAGAGGAGGCTATGATCGAGGCGGCTACCGG GGCCGCGGCGGGGACCGTGGAGGCTTCCGAGGGGGCCGGGGTGGTGGGGACAGAGGTGGC TTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGCAGGGAGAGGCCG TATTAATTAGCCTGGCTCCCCAGGTTCTGGAACAGCTTTTTGTCCTGTACCCAGTGTTAC CCTCGTTATTTTGTAACCTTCCAATTCCTGATCACCCAAGGGTTTTTTTGTGTCGGACTA TGTAATTGTAACTATACCTCTGGTTCCCATTAAAAGTGACCATTTTAGTTAAATTTTGTT CCTCTTCCCCCTTTTCACTTTCCTGGAAGATCGATGTCCCGATCAGGAAGGTAGAGAGTT TTCCTGTTCAGATTACCCTGCCCAGCAGGAACTGGAATACAGTGTTCGGGGAGAAGGCCA AATGATATCCTTGAGAGCAGAGATTAAACTTTTCTGTCATGGGGAAAGTTGGTGTATAAA TGAGAAATGAAGAACATGGGATGTCATGAGTGTTGGCCTAAATTTGCCCAGCTATGGGGA ATTTTTCCTTTACCACATTTATTTGCATACTGGTCTTAGTTTATTTGCAGCAGTTTATCC CTTTTTAAGAACTCTTTGATCTTTTGGCCCTTTTAATGGTGAGGCTCAAACAAACTACAT TTAAATGGGGCAGTATTCAGATTTGACCATGGTGGAGAGCGCTTAGCCACTCTGGGTCTT TCACAGGAAGGAGAGTAACTGAGTGCTGCAGGAGTTTGTGGAGTGGAGTCAGGATCTAGG AGGTGAGTGACTCCCTTCCTAGCTGCCCTGGTGAACAGCGCTTGGGTAGATACCTGCTAT AAGGAGACTGGTCTGGCTGGGTTACTTTCACATCCTGCCTGTACTCAGAGGGCTTGAGGT CATTGACATTATGAGATTTTAGGCTTGATCCCTTTTTGATTGGAGGGTGGAAGGCCCTCC TAAGGGAATGATAAGTGATAAGAGGGGGAAGGGGTTGCAGCCAATGAGTTAAAACCTTAG AGCAGTGCTCCTCAGCCTCTTACCATGTGGTTGTAAACTTGCACGTACCTGCCAACCAGT TATTTAGCATGCTTTTTATTTTAGTTACACAGAGCGTAACATTAACCCAAGAGCAGAAAG GTTTTATTTACAGGGTTTTCGAACTTGGTTTGTAAGACAGCTGCCATCACAAGCATAGCT TACAAATGTGCTGGGGACCCCTAATTGGGAAGTGCTTTCCTCTCAAATTTTTATTTTTTA TTTTTAGAGACAGAGTCTTGCTCTGTCATCCAGGCTGGAGTGCAGTGGCGTGATCTCGGC TCACTGTAGCCTCTGCCTCCTGAGTTTAAGCGATTCTCCTGCCTCAGGAGAATCCCAGCT TCTGAGTAGCTGAGACTACAGGCGTGGGCCACCATGCCCACCTAGTTTTTGCATTTTTAG TGGAGGTGTGGTTTCACTGTGTTGGCCAGGCTGGTCTCTTAACTCCTGACCTCAGGTGAT CCACCTGCCTTGGCCTCCCAAAGTGCTGGAATTACAGGCATGAGCCGCTGCATCTGGCCA TCCTCTCAAATTTTCAAGTGTTCCACAAGTATGTTCTCTACTGAAGAGTTGCTGCATCCT TGAATCTTGGGTGATTTGAGGCACAGAAACTATGACTTTATTTTTTGAGATGGAGTTTTG CTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGTTTTTCGGCTTACCGCAACTGCCGCCT CCTGGGTTCAAGCGATAGCTGGGATTACAGGCATGCGCCACCATGCCCAGCTAATTTATT TGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCCCGAC CTCAGGTGATGTGCACACCTCAGCCTCCCAATAAACCATGACTTTTAAGAGGAATAGCAG GTTTACTTCCCCTGCCAGCATTGGGGTGCTCTCTAAGCAACAGTAGGCGGAGAGTGGTCT GGCGTATTAAAAACAAAGGATCGTCAAGTGGGCCTTCCCAGGCATTGCTTTGACTTAGTA CATGTAGAGGATGTGGCAGTTCTCTCCGTCCCTGCCACTGCTGGTTTCTTTGTTAAATGT TTAGTTGAAATGGCCTGATACGATATTTGAGTAGTTCACTGTTGGTGCTTTGCCTAGCAG GATTCTAATCTTGCTTTGGTTGTGGTCCCCTGATGCCCTCCTGTTAGGAGTGGAGGAGGT CGAAGCTCCTTGTAAGATATGATTACTGGGACCATTAGTGTCAAGTTCCTGTGTCCTTCA AATGGCATATGTGATTGGCCTTGACCTTAAAAGGAAATAGGGTCCCAGGTGACTGTTTAG TGGGTAGGTCCAGTTTGGGGGGATCTTCCAGGAGAATGGATAGAGACACCTAGCAGCAGA GAGAACATTGGTGCCTCTCAAGCCAACCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTA CAGGTGCTTCCTCGCTACCACACCTGGGTAATTTTTTTTTTAATTACTTTTTTTTTTTTA AGAAACAGGGTTTCACTGGGTTGCCCAGGCTGGTCTTGAACTGGCCTCAAGTGACCTGCC TGCCTCAGCCTCCCAAAGTGCTGGGATCACAGGTGTGACCCACTGCGTTTGGCCAGAATA CTCTATTCTTACTGAATGATTGAAATCTGTCTTGAAGCATTAGGTGTCCCATTTTTGTGA GTTGGAATTGGGACAGGCTAAGTAGGAAGTGAGGAGGGTGGGGAGAGCTGTGCTGTAGGT CTGTTTGTCCCTTCCTTGATGTAGCCTTCAGTTAGCCCTTTCAGCTTTTTTCCCCATCTT GTGCCGGGCCTTCCTGGGTTTCAGTACTTGGATGTAGGGCTGCAGTTATGTCAGTGGTGG GTAGATTGACCAGGAATTAAGGTCTAGGGTCCAGCCCATGTGAGACTTGACTCACTGATC TACCTTTAGGCATGTCTTCCTTCCAGTCTCATCCTTTTTAAATTTTTTTTTTTTTTTTGA GACGGTCTCACTCTCACCCAGGCTGGATTGCAGTGGTGTGATCTCGACCAACTGCAACCT CTGCCTCCCACCCGCAAGCTATCTGCCCACCTCAGCCTCTGGAGTAGCTGGGACGGGACT ACAGGCACCTGCCACCATGACTGGCTAATTTTTTTTTGTATTTTTTGTGGAGATGGGGTC TTGCCATGTTGCTCAGGCTGGTCTGGTCTCAAAACTGCTCTGGGCTCAAGTGATTGTCCC ACTTTGGCCTCCCAGAGTGCTGGGATTAAGGTGTGAGATACTGTGTCCGGCTATGAAAAT TTTATTTTTAATTAACTTGTATATATTTATGGGGTACAATGTCCTATTTCTGTACATGTA CACATTGTGGAATCAAATCAGGCTAATATATCCATCACTTCATATCATTAGCATGAATGA GAACATACAAAGCCACTCTTAGAAAATTTTGAAATTTATGTTATTTCAGCCCTTTTATGC TGGAGGTTGCAAATGTTTTGTGAATAATCAGACCAAAAATAAAAACAAAAAATGATTGAC TTCAGTCATTCAGTAAGAA |
Protein Sequence | >2521 : length: 526 MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYE PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFS GNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY |