| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2356 |
Name | FPGS |
Synonym | folylpolyglutamate synthase;FPGS;folylpolyglutamate synthase |
Definition | folylpoly-gamma-glutamate synthetase|folylpolyglutamate synthase, mitochondrial|tetrahydrofolate synthase|tetrahydrofolylpolyglutamate synthase |
Position | 9q34.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Metabolism of folate and pterines;PID Reactome;501009 |
Pathway | Folate biosynthesis;KEGG PATHWAY;hsa00790 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Metabolism of vitamins and cofactors;Reactome;REACT:11193 |
Pathway | Tetrahydrofolate biosynthesis;PANTHER;P02742 |
Pathway | folate polyglutamylation I;BioCyc;PWY-2161 |
External Links | |
Links to Entrez Gene | 2356 |
Links to all GeneRIF Items | 2356 |
Links to iHOP | 2356 |
Sequence Information | |
Nucleotide Sequence | >2356 : length: 2364 AGACTATAGCGTCCCCGCCCCGGGTTGGGAAGTGGGAAGTGGCACAGGAGCTAGGATCCA GAAGCCCAGAGGCTCAGCGGTGCTTCTGGAGTTCCAGTGATCCCGGAGTCTGAACCGGCA GTGAGAGTGGGGAAAGAGGGCTAGGCTAACAGTGCTGGCATGGCAGGCGGGCCTGGTACT GGCCTTGTTGCCCTGGCTTGGCCACTGGTCTGCTGGCTGTCTCTGTGCCTGTGGACCCTG AGTGAGCCTTAACCTACTATCTGGGCACTGTGGTTGCCAGGATGCCGTGCGCATGCTCAA TACCCTGCAGACCAATGCCGGCTACCTGGAGCAGGTGAAGCGCCAGCGGGGTGACCCTCA GACACAGTTGGAAGCCATGGAACTGTACCTGGCACGGAGTGGGCTGCAGGTGGAGGACTT GGACCGGCTGAACATCATCCACGTCACTGGGACGAAGGGGAAGGGCTCCACCTGTGCCTT CACGGAATGTATCCTCCGAAGCTATGGCCTGAAGACGGGATTCTTTAGCTCTCCCCACCT GGTGCAGGTTCGGGAGCGGATCCGCATCAATGGGCAGCCCATCAGTCCTGAGCTCTTCAC CAAGTACTTCTGGCGCCTCTACCACCGGCTGGAGGAGACCAAGGATGGCAGCTGTGTCTC CATGCCCCCCTACTTCCGCTTCCTGACACTCATGGCCTTCCACGTCTTCCTCCAAGAGAA GGTGGACCTGGCAGTGGTGGAGGTGGGCATTGGCGGGGCTTATGACTGCACCAACATCAT CAGGAAGCCTGTGGTGTGCGGAGTCTCCTCTCTTGGCATCGACCACACCAGCCTCCTGGG GGATACGGTGGAGAAGATCGCATGGCAGAAAGGGGGCATCTTTAAGCAAGGTGTCCCTGC CTTCACTGTGCTCCAACCTGAAGGTCCCCTGGCAGTGCTGAGGGACCGAGCCCAGCAGAT CTCATGTCCTCTATACCTGTGTCCGATGCTGGAGGCCCTCGAGGAAGGGGGGCCGCCGCT GACCCTGGGCCTGGAGGGGGAGCACCAGCGGTCCAACGCCGCCTTGGCCTTGCAGCTGGC CCACTGCTGGCTGCAGCGGCAGGACCGCCATGGTGCTGGGGAGCCAAAGGCATCCAGGCC AGGGCTCCTGTGGCAGCTGCCCCTGGCACCTGTGTTCCAGCCCACATCCCACATGCGGCT CGGGCTTCGGAACACGGAGTGGCCGGGCCGGACGCAGGTGCTGCGGCGCGGGCCCCTCAC CTGGTACCTGGACGGTGCGCACACCGCCAGCAGCGCGCAGGCCTGCGTGCGCTGGTTCCG CCAGGCGCTGCAGGGCCGCGAGAGGCCGAGCGGTGGCCCCGAGGTTCGAGTCTTGCTCTT CAATGCTACCGGGGACCGGGACCCGGCGGCCCTGCTGAAGCTGCTGCAGCCCTGCCAGTT TGACTATGCCGTCTTCTGCCCTAACCTGACAGAGGTGTCATCCACAGGCAACGCAGACCA ACAGAACTTCACAGTGACACTGGACCAGGTCCTGCTCCGCTGCCTGGAACACCAGCAGCA CTGGAACCACCTGGACGAAGAGCAGGCCAGCCCGGACCTCTGGAGTGCCCCCAGCCCAGA GCCCGGTGGGTCCGCATCCCTGCTTCTGGCGCCCCACCCACCCCACACCTGCAGTGCCAG CTCCCTCGTCTTCAGCTGCATTTCACATGCCTTGCAATGGATCAGCCAAGGCCGAGACCC CATCTTCCAGCCACCTAGTCCCCCAAAGGGCCTCCTCACCCACCCTGTGGCTCACAGTGG GGCCAGCATACTCCGTGAGGCTGCTGCCATCCATGTGCTAGTCACTGGCAGCCTGCACCT GGTGGGTGGTGTCCTGAAGCTGCTGGAGCCCGCACTGTCCCAGTAGCCAAGGCCCGGGGT TGGAGGTGGGAGCTTCCCACACCTGCCTGCGTTCTCCCCATGAACTTACATACTAGGTGC CTTTTGTTTTTGGCTTTCCTGGTTCTGTCTAGACTGGCCTAGGGGCCAGGGCTTTGGGAT GGGAGGCCGGGAGAGGATGTCTTTTTTAAGGCTCTGTGCCTTGGTCTCTCCTTCCTCTTG GCTGAGATAGCAGAGGGGCTCCCCGGGTCTCTCACTGTTGCAGTGGCCTGGCCGTTCAGC CTGTCTCCCCCAACACCCCGCCTGCCTCCTGGCTCAGGCCCAGCTTATTGTGTGCGCTGC CTGGCCAGGCCCTGGGTCTTGCCATGTGCTGGGTGGTAGATTTCCTCCTCCCAGTGCCTT CTGGGAAGGGAGAGGGCCTCTGCCTGGGACACTGCGGGACAGAGGGTGGCTGGAGTGAAT TAAAGCCTTTGTTTTTTAAAGAAA |
Protein Sequence | >2356 : length: 587 MSRARSHLRAALFLAAASARGITTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGGPPLTLGLEGE HQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW PGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRVLLFNATGDRD PAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDEE QASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSP PKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ |