| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 23239 |
Name | PHLPP1 |
Synonym | PHLPP|PLEKHE1|SCOP;PH domain and leucine rich repeat protein phosphatase 1;PHLPP1;PH domain and leucine rich repeat protein phosphatase 1 |
Definition | PH domain leucine-rich repeat-containing protein phosphatase 1|PH domain-containing family E member 1|SCN circadian oscillatory protein|pleckstrin homology domain containing, family E (with leucine rich repeats) member 1|suprachiasmatic nucleus circadian |
Position | 18q21.33 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
External Links | |
Links to Entrez Gene | 23239 |
Links to all GeneRIF Items | 23239 |
Links to iHOP | 23239 |
Sequence Information | |
Nucleotide Sequence | >23239 : length: 6411 CCGCGACCCGGGCGGGGAGGGCGTGTGTCGGGGGGGCGGTGGCGGCGAGGCGGGCGCGCG GGATGGAACACTGAGACACCGACGGAATGCTCCGAATCGCCACATAATCCCCTGGAACGG CCGCGCACAACGCCATTGGCTTCTCCCTTCTCCGCGCGCCGCCGCCGTCTCCCACCTCCG CCTCATCGCCTCCCTCTCCGCCCGCTGCCTCCGGAGCTGGGGGGGAAACGCGAAGCCCCA CTGCAATGGAGCCCGCCGCCGCGGCCACGGTACAGCGACTCCCCGAGCTCGGCAGGGAGG ACCGAGCTTCGGCTCCGGCGGCCGCCGCTGCGGCAGCAGCAGCAGCAGCGGCGGCCGCGG CGGCTCTGGCGGCGGCGGCCGGGGGCGGCCGGAGTCCGGAGCCCGCGCTGACCCCGGCGG CCCCGAGCGGCGGGAACGGCAGCGGCAGCGGGGCGCGGGAAGAGGCCCCAGGCGAGGCGC CGCCGGGGCCGCTGCCGGGCAGAGCGGGGGGTGCCGGGCGCAGGAGGCGGCGCGGGGCGC CCCAGCCCATTGCCGGCGGGGCTGCCCCCGTACCCGGGGCCGGCGGCGGCGCCAACTCCC TCCTGCTGAGGAGAGGGCGGCTGAAGAGGAATCTGTCCGCGGCCGCCGCGGCCGCCTCCT CGTCGTCGTCGTCCTCGGCCGCTGCTGCCTCGCACTCCCCCGGCGCTGCCGGCCTCCCCG CCTCCTGCTCGGCCTCGGCGTCGCTGTGCACCCGGAGCCTGGACAGGAAGACGCTGCTTC TGAAGCACCGGCAGACGCTGCAGCTGCAGCCGTCGGACCGGGACTGGGTGAGGCACCAGC TCCAGCGCGGCTGCGTGCACGTCTTCGACCGCCACATGGCCTCGACCTACCTGCGCCCGG TGCTCTGCACACTGGACACCACGGCCGGCGAGGTGGCCGCCCGCCTGCTGCAGCTGGGCC ACAAAGGCGGCGGCGTGGTGAAGGTGCTGGGCCAGGGGCCCGGAGCCGCCGCCGCCCGGG AGCCCGCTGAACCGCCCCCCGAGGCCGGCCCCCGGCTGGCGCCCCCGGAGCCGCGGGACT CGGAGGTACCGCCCGCGAGGAGCGCGCCGGGTGCCTTCGGGGGGCCTCCGCGCGCGCCCC CCGCCGACCTACCCCTGCCCGTCGGCGGCCCGGGCGGGTGGTCGCGCCGCGCCAGCCCAG CGCCCTCGGACTCCAGCCCCGGCGAGCCGTTCGTTGGGGGCCCTGTCTCTTCGCCCCGCG CCCCACGGCCTGTGGTCTCCGACACCGAGAGCTTCAGTCTGAGTCCCAGCGCCGAGAGCG TGTCTGACCGGTTGGACCCCTACAGCAGCGGCGGCGGCTCCTCGTCGTCGTCGGAAGAGC TCGAGGCCGACGCAGCCTCGGCCCCGACGGGGGTCCCGGGCCAGCCCCGCCGTCCCGGCC ACCCCGCGCAGCCCCTCCCGCTTCCCCAGACGGCTTCCTCGCCTCAGCCGCAGCAGAAAG CCCCGAGGGCCATTGACAGCCCGGGCGGGGCCGTCCGCGAGGGGTCGTGCGAGGAGAAGG CAGCGGCAGCCGTGGCCCCGGGAGGCCTCCAGTCTACCCCCGGGAGGAGCGGGGTGACCG CGGAGAAGGCGCCTCCGCCGCCCCCGCCGCCCACCCTGTACGTGCAGCTCCACGGAGAGA CCACCCGGCGCTTGGAGGCGGAGGAGAAGCCATTGCAGATCCAAAATGACTACCTCTTCC AACTGGGATTTGGGGAGCTGTGGAGGGTGCAGGAGGAAGGCATGGACTCGGAGATTGGCT GCCTCATCCGCTTCTATGCAGGAAAACCTCACAGCACGGGTAGCTCTGAACGGATTCAGC TCTCAGGAATGTATAATGTCCGTAAAGGCAAGATGCAGTTGCCAGTGAACCGATGGACAA GACGCCAAGTCATCCTATGTGGGACCTGCCTGATAGTATCATCTGTGAAAGACAGCTTGA CCGGAAAGATGCATGTTCTGCCACTAATTGGTGGAAAAGTAGAAGAAGTGAAAAAGCACC AACACTGTTTAGCATTTAGCTCCTCTGGACCCCAAAGCCAGACTTACTACATTTGCTTTG ATACTTTCACAGAATACTTAAGGTGGCTGCGACAAGTCTCCAAGGTTGCATCCCAGCGCA TTAGCTCAGTGGACCTCTCGTGTTGTAGCCTGGAACATCTGCCTGCCAACCTCTTCTACA GCCAAGACCTCACTCATCTCAATTTAAAACAAAACTTCCTAAGGCAGAACCCTAGCCTTC CAGCTGCCAGGGGGCTTAATGAACTGCAAAGGTTCACCAAGTTGAAGAGTCTTAACCTTT CCAATAATCATTTAGGGGACTTCCCACTGGCAGTCTGCAGTATTCCAACCCTGGCAGAGC TGAACGTGTCCTGCAATGCCCTGCGATCAGTCCCGGCAGCCGTTGGAGTGATGCACAACT TACAGACATTTTTGTTGGATGGAAACTTTCTCCAATCCCTTCCTGCTGAGTTGGAGAACA TGAAGCAGCTTAGTTATCTGGGTCTTTCTTTCAATGAATTTACTGACATTCCCGAAGTAT TGGAGAAATTGACTGCTGTGGATAAACTTTGTATGTCTGGAAACTGTGTGGAGACCCTTA GGCTACAGGCTTTAAGAAAAATGCCTCACATTAAACATGTGGATCTAAGGTTGAACGTAA TTAGGAAGCTGATAGCAGATGAAGTGGACTTTCTACAGCATGTTACTCAGCTTGACCTAC GAGACAATAAGCTTGGTGATCTAGATGCTATGATTTTCAACAACATTGAAGTTTTACACT GTGAAAGGAATCAACTGGTCACATTAGACATCTGTGGCTATTTCCTAAAAGCGCTCTATG CCTCTTCTAATGAACTTGTTCAACTTGATGTTTACCCAGTTCCAAATTATCTGTCCTACA TGGATGTTTCAAGGAACCGCTTAGAAAATGTGCCTGAGTGGGTATGTGAAAGCCGAAAGC TAGAAGTTTTGGATATTGGCCATAATCAAATATGTGAACTTCCTGCCCGCTTATTTTGTA ATAGCAGTCTCCGGAAACTACTGGCAGGACACAACCAGTTGGCAAGGCTGCCTGAAAGGC TAGAAAGAACCTCGGTGGAGGTCTTGGATGTGCAACACAACCAGCTCCTTGAGCTCCCAC CTAACCTTCTGATGAAGGCTGACAGCCTGAGATTCCTGAACGCCTCTGCGAACAAACTGG AAAGCCTTCCTCCAGCCACGCTTTCCGAAGAGACAAACAGTATCTTACAAGAGTTGTATT TGACAAATAACAGCCTCACAGACAAATGTGTGCCCTTGTTAACGGGACACCCCCATTTGA AGATCCTTCACATGGCCTATAACCGACTTCAGAGTTTTCCAGCAAGTAAAATGGCGAAAC TGGAGGAACTTGAAGAAATTGATCTCAGTGGGAATAAGCTGAAAGCCATCCCAACAACGA TCATGAATTGCAGGCGCATGCACACCGTGATTGCTCACTCCAACTGCATCGAGGTCTTTC CCGAAGTTATGCAGCTCCCAGAGATCAAGTGTGTGGACCTGAGCTGTAATGAGCTAAGTG AAGTCACATTACCAGAAAACCTGCCTCCCAAACTGCAGGAGCTAGACCTGACTGGAAACC CGCGCCTTGTCCTTGATCACAAAACCCTGGAACTACTGAATAATATCCGCTGTTTCAAGA TTGATCAGCCTTCTACAGGAGACGCTTCCGGAGCCCCAGCTGTATGGAGTCATGGTTACA CTGAAGCTTCGGGGGTAAAAAACAAGTTGTGTGTCGCAGCCCTGTCGGTGAATAACTTCT GTGACAACCGCGAAGCCCTGTATGGTGTGTTTGACGGAGACCGGAATGTGGAGGTGCCCT ACCTTCTCCAGTGCACTATGAGTGACATTTTGGCTGAAGAGCTGCAAAAAACAAAAAACG AAGAAGAATACATGGTCAATACATTCATTGTCATGCAAAGGAAACTTGGAACTGCTGGGC AGAAGCTTGGTGGTGCCGCTGTCCTTTGTCATATCAAGCATGACCCTGTGGATCCAGGAG GATCCTTCACCTTGACCTCTGCTAATGTGGGCAAGTGCCAAACAGTTCTCTGTCGAAATG GAAAGCCGCTGCCTCTGTCCAGATCTTACATCATGAGCTGTGAAGAAGAGCTGAAGAGGA TTAAACAGCACAAGGCCATTATCACTGAGGATGGCAAGGTGAACGGAGTGACTGAGTCCA CGCGCATCCTGGGCTACACCTTCCTCCATCCCAGTGTGGTGCCTCGCCCCCACGTGCAGT CCGTGCTCCTGACTCCCCAGGATGAGTTCTTCATCCTAGGCAGTAAGGGGTTGTGGGACA GCCTGTCCGTCGAGGAGGCCGTGGAAGCCGTGCGCAACGTGCCCGATGCCCTGGCTGCTG CCAAGAAGCTGTGTACCCTGGCCCAGAGCTACGGCTGCCACGACAGCATCAGCGCTGTGG TGGTGCAGCTCAGTGTCACTGAGGACAGCTTCTGCTGCTGCGAGCTCAGCGCCGGTGGGG CTGTGCCACCACCCAGTCCTGGCATCTTTCCTCCCTCAGTGAACATGGTGATCAAGGATC GGCCCTCAGATGGGCTGGGCGTGCCGTCCTCCAGCAGCGGCATGGCTTCCGAGATTAGCA GTGAGCTCTCCACTTCTGAGATGAGCAGCGAGGTGGGGTCAACAGCCTCCGATGAGCCCC CGCCCGGAGCCCTAAGCGAGAACAGCCCTGCCTACCCCAGTGAGCAGCGCTGCATGCTCC ACCCCATCTGTCTGTCCAACTCCTTCCAGCGCCAGCTATCCAGCGCCACGTTCTCTAGCG CCTTCTCCGACAACGGCCTTGACAGTGACGATGAGGAGCCCATCGAGGGCGTCTTCACCA ACGGCAGCCGGGTGGAGGTGGAGGTGGACATCCACTGCAGCCGGGCCAAGGAGAAGGAGA AACAGCAGCACCTGCTTCAGGTGCCAGCAGAGGCCAGTGATGAGGGCATTGTCATCAGCG CCAACGAGGATGAGCCAGGTCTGCCCAGGAAGGCAGACTTCTCTGCCGTTGGGACCATTG GGCGCCGGAGGGCCAATGGCTCTGTTGCGCCCCAGGAAAGGAGCCACAATGTGATAGAGG TGGCTACAGACGCACCTCTTCGAAAGCCTGGAGGCTATTTTGCTGCCCCGGCTCAGCCGG ATCCTGATGATCAGTTTATCATACCCCCGGAGCTGGAAGAGGAGGTCAAAGAAATCATGA AGCATCACCAGGAGCAACAGCAGCAGCAGCAGCCGCCACCACCCCCTCAGCTCCAGCCGC AGCTGCCGCGGCACTACCAGCTGGACCAGCTGCCAGATTATTACGACACGCCACTATGAC CCAGCCGAGCTGTTTAACAAATAAACTAACCACAAAAGACTGAGTTGCAAGAGTCTCCCA GGCTCACATTAAACCAGGGGTTTTACTCCACATCCTTCCCCCAGACACTGTTCCCAACCT GTCATCGCAGCTAATCTGTAGGTTCTCTTTCTTTGGGTTATTTTTTTAAGTAATCACCAC TTTCTTCTAGTGATGCTTTACCAATATGATTTACATTTGTTAACTTCTCCCCCTAACATA TCAGATATGTAAAGACAAAGAACAAAAGGTTTAATATATTACAGAGAAACAGTTAATGAT AATGTAATATTTTTTAAAATGGCTTTTTGTTGTTTGTTTGGAAGGCAGGGCAGGCTGCCG TTGCTAAATGATTTAATAATATTGTAATTCTGTATTTCTTTGGGGGGAAAAGGCTTTTGT TTTGTTTTGTTTTGTTTTGTTTTGTTTTTGTCTTGAAAATAATAGACATTTGTAGAATAT GGAGACTAACTCCTAGGAGTTGCTTTACTCTGTCAGGTGACTTAAGTCACTGGGATTCAC TAATTTTCTCTGAGAGAACAGCTGATTGAGAATTTCCATTGTAAATAGCTCAGTGTTGTA TAGTGAGGCTTACGATGTTTTGTAGTCTTGGCGTAAGGACACAGCCCAAGTAACTGACGT TTCCCCTCCCCCTCCCCTCTGAGGAGCCTGCCTGCCTCACAACTCACCCTCACTTCACTG AATGAGGAGGCTGAGCAGCTGCAGTGTTTCTGTCCGGAGGAAATGGATCTTAGGCCACTG GACAAGAACCTGCACCCAAGGGCCCTGAACCCATTTTCCTCCCCTGTCCCAGCCTTCCCA CTTTGACAGACACTTTTAACTGTGTTCCTTACTGCTGCCACAATCAGCATGGTTGTATAG TGCCCCATTAGGCCATTTACATACCCAGAGTTATACTCAAGCAGAATGCACAAATGGACA TGTCATAATTTTTGTTACAATAAATATGAAATTTACAAGTATTTACAAGTA |
Protein Sequence | >23239 : length: 1717 MEPAAAATVQRLPELGREDRASAPAAAAAAAAAAAAAAAALAAAAGGGRSPEPALTPAAP SGGNGSGSGAREEAPGEAPPGPLPGRAGGAGRRRRRGAPQPIAGGAAPVPGAGGGANSLL LRRGRLKRNLSAAAAAASSSSSSSAAAASHSPGAAGLPASCSASASLCTRSLDRKTLLLK HRQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDTTAGEVAARLLQLGHK GGGVVKVLGQGPGAAAAREPAEPPPEAGPRLAPPEPRDSEVPPARSAPGAFGGPPRAPPA DLPLPVGGPGGWSRRASPAPSDSSPGEPFVGGPVSSPRAPRPVVSDTESFSLSPSAESVS DRLDPYSSGGGSSSSSEELEADAASAPTGVPGQPRRPGHPAQPLPLPQTASSPQPQQKAP RAIDSPGGAVREGSCEEKAAAAVAPGGLQSTPGRSGVTAEKAPPPPPPPTLYVQLHGETT RRLEAEEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLS GMYNVRKGKMQLPVNRWTRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKHQH CLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQ DLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELN VSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLE KLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRD NKLGDLDAMIFNNIEVLHCERNQLVTLDICGYFLKALYASSNELVQLDVYPVPNYLSYMD VSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLE RTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLT NNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIM NCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGNPR LVLDHKTLELLNNIRCFKIDQPSTGDASGAPAVWSHGYTEASGVKNKLCVAALSVNNFCD NREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMVNTFIVMQRKLGTAGQK LGGAAVLCHIKHDPVDPGGSFTLTSANVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIK QHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSL SVEEAVEAVRNVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAV PPPSPGIFPPSVNMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPP GALSENSPAYPSEQRCMLHPICLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNG SRVEVEVDIHCSRAKEKEKQQHLLQVPAEASDEGIVISANEDEPGLPRKADFSAVGTIGR RRANGSVAPQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKH HQEQQQQQQPPPPPQLQPQLPRHYQLDQLPDYYDTPL |